• Title/Summary/Keyword: curvilinear

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Relationship between Plasma Concentrations of Haloperidol and Its Metabolite, Reduced Haloperidol, and Clinical Response in Schizophrenia (정신분열증 환자에서의 Haloperidol 및 Reduced Haloperidol의 혈장농도와 임상반응과의 상관성)

  • Park, Kyung-Ho;Kim, Mu-Jin;Lee, Myung-Gul;Shim, Chang-Koo;Lee, Min-Hwa
    • Journal of Pharmaceutical Investigation
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    • v.23 no.3
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    • pp.165-177
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    • 1993
  • The relationship between the plasma haloperidol (HP) concentration and clinical response, and the effects of its active metabolite, reduced haloperidol (RH) on clinical response of HP were investigated in schizophrenic patients. In clinical study I, with 17 schizophrenic patients (male 8, fermale 9) who were administered with three different fixed doses of HP (15, 30 and 50 mg/day) for 3 weeks, the concentrations of HP and RH in plasma and blood and clinical response had been checked before and every week during the study. The clinical response was evaluated by the method of brief psychiatric rating scale (BPRS), and relative improvement of clinical response based on baseline BPRS (before drug treatment) was calculated. The concentrations of HP and RH in plasma and blood were assayed by HPLC. In clinical study II, the plasma RH/HP concentration ratios were checked in 11 patients who were administered with high doses of HP, over 60 mg a day, because of the poor clinical response at usual doses of HP. Plasma HP concentration and relative improvement of BPRS at 3 week in schizophrenic patients showed a 'curvilinear' relationship, and the clinical response was improved relatively over 50% based on the baseline BPRS in the range of $5{\sim}57\;ng/ml $ of HP in plasma. Also, the plasma RH concentrations were increased nonlinearly as the plasma HP concentration increased, and in high plasma HP concentration, over 30 ng/mI, clinical response gradually decreased, while the plasma RH/HP concentration ratio increased nonlinearly. Blood partition coefficients of HP and RH were not changed according to daily HP dose and duration of drug therapy. From these results, it is noted that the higher plasma RH/HP concentration ratio, resulted from the accumulation of RH as HP concentration increased, might explain the 'curvilinear' decrease of HP clinical response.

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Conflict Management and Turnover Intention: Multi-level Curvilinearity and the Moderating Role of Trust in Leader (갈등관리와 이직의도: 다수준 비선형성과 리더신뢰의 조절효과)

  • Kim, Cheolyoung;Park, Jisung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.11
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    • pp.253-263
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    • 2018
  • This paper examined the U-shape curvilinear relationship between team level conflict management and individual level turnover intention by using exit-voice theory, bandwagon effect, and social loafing theory. In addition to the non-linear relationship between team-level conflict management and individual-level turnover intentions, we also examined how trust in leaders has a moderating effect on this relationship. The samples were collected from a South Korean manufacturing company with 331 team members from 48 teams and items were measured twice to avoid common method biases. The intercepts-as-outcomes model of hierarchical linear modelling was conducted to verify the hypothesis. Results supported the cross-level curvilinear hypothesis which indicated that employees' turnover intention sharply decreased if the activeness of group conflict management was small and increases slightly, but this tendency moderated as activeness increases. After passing the lowest point, their turnover intention increased in the end. However, the moderation effect of trust in leader on this relationship was not statistically significant and hypothesis 2 was rejected. This paper explained the effects of group dynamics of conflict management on individual turnover intention. Such evidence may elucidate the importance of managing the social loafing behavior on conflict management process. This paper examined the sequential, multi-level, and curvilinear relationship between conflict management and turnover intention. Organizations and managers will benefit from avoiding the human resource loss by managing the conflict management process.

How self-estimation bias in peer relationship relates to subjective well-being and to interpersonal behaviors: Testing the optimal margin hypothesis (또래관계에 대한 자기평가편향과 주관적 안녕감, 대인행동의 관계: 적정한계선 가설의 검증)

  • Lee, Eunju;Yeom, Hyeseon
    • Korean Journal of School Psychology
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    • v.17 no.3
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    • pp.263-286
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    • 2020
  • The purpose of this study was to explore how overly positive self-estimations in peer relationships relate to subjective well-being and to the occurrence of interpersonal behaviors supporting basic psychological needs among elementary school students. This study tested the optimal margin hypothesis of positive illusion by examining the curvilinear relationship between these variables. The sample consisted of 346 fifth and sixth grade students. The self-criterion residual method was used to derive self-estimation bias scores by regressing the real peer relations index (i.e., In-degree) on their perceived peer relationship qualities. The results showed that girls more strongly overestimated the quality of their peer relationships than boys. Self-estimation biases had a positive curvilinear relationship with negative affects and a negative curvilinear relationship with relatedness needs supporting interpersonal behaviors. These results supported the existence of the optimal margin of positive illusion because overestimations of the quality of peer relationships were associated with lower levels of negative affects and relatedness needs-supporting interpersonal behaviors, though these benefits flattened out and no further benefit was observed after an optimal level of overestimation. However, self-estimation bias was linearly associated with positive affect, autonomy needs-supporting interpersonal behaviors, and competence needs-supporting interpersonal behaviors. These results indicated that optimal margin hypothesis was not supported for all outcome variables.

The perceptual judgment of sound prolongation: Equal-appearing interval and direct magnitude estimation (연장음 길이에 따른 비유창성 정도 평가: 등간척도와 직접크기평정 비교 연구)

  • Jin Park;Hwajung Cha;Sejin Bae
    • Phonetics and Speech Sciences
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    • v.15 no.3
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    • pp.59-67
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    • 2023
  • This study aimed to propose an appropriate evaluation method for the perceived level of speech disfluency based on sound prolongation (i.e., increased duration of segments). To this end, 34 Korean-speaking adults (9 males, 25 females, average age: 32.9 yrs.) participated as raters in this study. The participants listened to sentences containing a total of 25 stimuli with the Korean voiceless fricative /s/ extended by 80-ms increments up to 2,000 ms (i.e., 285 ms, 365 ms., ..., 2,125 ms, 2,205 ms), and evaluated them using an equal-appearing interval scale (EAI, 1-7 points, where 1 represents "normal" and 7 represents "severe"). Subsequently, based on the interval-scale results, the sentence stimuli with the prolonged voiceless fricative corresponding to the mild-to-moderate level (rated as 4 points) were selected as the reference modulus for direct magnitude estimation (DME). After scatter plots were created for the two evaluation results, the relationship between the two measured mean values was analyzed using a curve estimation method for the observed data with the highest R2-value to determine whether a linear or curvilinear approximation fit the data better. A curvilinear relationship between the two evaluation results was indicated, suggesting that DME is a more appropriate evaluation method than the EAI scale for assessing the perceived level of disfluency based on sound prolongation.

A Study of Family Adaptability and Cohesion Evaluation Scale(FACES) (가족의 응집 및 적응 평가 척도에 관한연구)

  • 김수연
    • Journal of the Korean Home Economics Association
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    • v.35 no.1
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    • pp.59-74
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    • 1997
  • FACES II & III do not capture the high extremes of the dimension and are linear rather than curvilinear measure. FACES IV is the latest revision of FACES series and can capture two extreme dimension of Circumplex Model. The purpose of this study is to examine reliability and validity of reconstructed FACES using by FACES II, III, IV. Factor analysis showed that Cohesion and Adaptability consisted 3 factors (disengaged, connected, emmeshed/rigid, flexble, chaotic) Extremes on each dimension conceptually were opposite and they were uncorrelated with each other. FACES effectively predicted family function. Reliability coefficients of subscales ranged from 61~85 Reconstructed FACES had good internal consistency and construct and criterion related validity.

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A Study of Family Adaptability and Cohesion Evaluation Scale II (가족의 응집 및 적응 척도에 관한 연구 II)

  • 김수연
    • Journal of the Korean Home Economics Association
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    • v.35 no.6
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    • pp.205-219
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    • 1997
  • FACES II & III did not capture high extremes of Cohesion and Adaptability dimension, and were linear rather than curvilinear measure. The purpose of this study was to examine reliability and validity of revised FACES using by FACES II,III,IV. Factor analysis showed that Cohesion and Adaptability dimension consisted each 3 factors(disengaged, connected, enmeshed / rigid, flexible, chaotic). Extremes on each dimension conceptually were opposite and they were uncorrelated with each other. Revised FACES effectively predicted family function. Reliability coefficients of subscales ranged form .68~.82. Revised FACES had good internal consistency, and construct and criterion related validity.

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Evaluation of the Influence of a Convective Term Caused by Various Finite Difference Schemes in General Curvature Coordinate (일반곡선 좌표계 사용시 대류항의 차분스킴에 의한 영향 평가)

  • 이연원
    • Journal of Advanced Marine Engineering and Technology
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    • v.18 no.3
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    • pp.94-101
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    • 1994
  • To develope the new simulator for the analysis of fluid flow information, the influence of various convective difference schemes were evaluated. General curvilinear coordinate system with nonorthogonal grids was adopted for the successful analysis of various complex geometries. Computation results show that if we can not obtain full grid numbers within available computational environment, we need to use higher order finite difference schemes to keep the prediction accuracy.

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The development of mobile robot for hostile environment controlled by three motors (3개의 모터로 구동되는 극한작업용 이동로보트의 개발)

  • 권대갑;차영엽;염도성
    • 제어로봇시스템학회:학술대회논문집
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    • 1990.10a
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    • pp.704-709
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    • 1990
  • This study presents the structure and the gate control algorithm of KAMOBOT (KAIST Mobile Robot). The mobile robot has a six-legged, cylindrical configuration, each leg of which is equiped with a wheel at the bottom. The robot can go up and down stairs, go over obstacles, move along curvilinear paths and rotate around it's geometric center. Such maneuverability can be achieved by using only three electric motors.

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A Study on the Characteristic Analysis of Linear Induction Motor according to Transversal Displacement (횡방향 편의에 따른 선형 유도 전동기의 특성해석에 관한 연구)

  • 임달호;김완식;최창규;김규탁
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.38 no.10
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    • pp.811-819
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    • 1989
  • An analysis method about Transverse Edge Effect is suggested which can be applied even in transversal decline when the mover of linear induction motor runs along a curvilinear path. The criteria for linear induction motor design is proposed by indentifying the influence of the ratio of width and displacement of primary and secondary.

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The Analyses about Axisymmetric Deformation of a thin pressure vessel by orthotropic composites (Orthotropic 복합재료로 만든 두께가 얇은 압력용기의 변형에 관한 연구)

  • 김형원;최용규
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2003.05a
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    • pp.156-159
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    • 2003
  • The analytic solution of displacements of thin cylindrical pressure vessel made by carbon fiber T700/Epoxy was obtained using equilibrium equations of orthogonal curvilinear coordinate system. Equilibrium equations with the assumed displacement field were derived from a reasonable description of the behavior of thin elastic shells using principle of virtual work. Some analyses of the theoretical solution are presented and compared with the results of hydraulic tests of the pressure vessel.

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