• 제목/요약/키워드: cumulative duration

검색결과 191건 처리시간 0.025초

소수력발전소의 수문학적 성능특성 분석 (Hydrologic Analysis Methods for Performance Characteristics of Small Hydro Power Plant)

  • 박완순;이철형;심명필
    • 대한토목학회논문집
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    • 제14권5호
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    • pp.1159-1166
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    • 1994
  • 본 연구는 소수력발전소의 성능분석 및 예측기법에 관한 것으로 소수력발전소에서의 유량지속곡선을 작성하기 위해서 Weibull 분포의 누가밀도함수를 사용하여 강수자료를 특성화하였고, 특성화된 유량지속함수를 이용한 성능분석모형을 개발하였다. 또한 한강수계에 위치한 안흥소수력발전소를 대상으로 개발된 성능분석모형을 이용하여 발전소의 성능특성을 분석하였다. 분석결과, 수문자료가 부족한 소수력발전소의 경우, 개발된 성능분석모형을 이용하여 기존 소수력발전소에 대한 성능분석 뿐만 아니라 발전소의 초기 설계시 설계유량, 설비용량, 연 평균가동율 및 연간 발전량 등의 성능 예측에도 효과적으로 이용할 수 있음을 확인하였다.

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Strain-based seismic failure evaluation of coupled dam-reservoir-foundation system

  • Hariri-Ardebili, M.A.;Mirzabozorg, H.;Ghasemi, A.
    • Coupled systems mechanics
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    • 제2권1호
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    • pp.85-110
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    • 2013
  • Generally, mass concrete structural behavior is governed by the strain components. However, relevant guidelines in dam engineering evaluate the structural behavior of concrete dams using stress-based criteria. In the present study, strain-based criteria are proposed for the first time in a professional manner and their applicability in seismic failure evaluation of an arch dam are investigated. Numerical model of the dam is provided using NSAD-DRI finite element code and the foundation is modeled to be massed using infinite elements at its far-end boundaries. The coupled dam-reservoir-foundation system is solved in Lagrangian-Eulerian domain using Newmark-${\beta}$ time integration method. Seismic performance of the dam is investigated using parameters such as the demand-capacity ratio, the cumulative inelastic duration and the extension of the overstressed/overstrained areas. Real crack profile of the dam based on the damage mechanics approach is compared with those obtained from stress-based and strain-based approaches. It is found that using stress-based criteria leads to conservative results for arch action while seismic safety evaluation using the proposed strain-based criteria leads to conservative cantilever action.

Temporal Changes in the Hepatic Fatty Liver in Mice Receiving Standard Lieber-DeCarli Diet

  • Yin, Hu-Quan;Lee, Byung-Hoon
    • Toxicological Research
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    • 제24권2호
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    • pp.113-117
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    • 2008
  • Chronic exposure to ethanol induces cumulative damage to the liver starting from fatty infiltration to cirrhosis depending on the dose and duration of exposure. The whole process leading to the development of alcoholic liver disease is very complex and the mechanisms involved are not fully understood. Among many experimental animal models, Lieber-DeCarli liquid diet provides moderate to severe pathophysiological outcome depending on the compositional changes. In the present study, we investigated the temporal changes in the early phase hepatic disease in rats fed with standard Lieber-DeCarli diet. Male Wistar rats were fed with Lieber-Decarli ethanol diet for 6 weeks and the liver samples were obtained after 2, 4 and 6 weeks. Mild fatty infiltration was observed in 2 weeks of feeding and it became evident in 4 and 6 week samples. The level of hepatic triglyceride showed a good agreement with the data obtained in the pathological analysis. Feeding mice with ethanol diet resulted in the maturation and translocation of SREBP-1 to nucleus in the liver. Western blot analysis of the pooled liver sample of control and ethanol fed animals showed a clear-cut time-dependent increase in the expression of nSREBP-1. These data provide important information for selecting proper time point in experimental intervention study in the field of drug development for alcoholic liver disease.

Lethal Effects of Helianthemum lippii (L.) on Acanthamoeba castellanii Cysts in Vitro

  • Badria, F.A.;Hetta, M.H.;Sarhan, Rania M.;Ezz El-Din, H.M.
    • Parasites, Hosts and Diseases
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    • 제52권3호
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    • pp.243-249
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    • 2014
  • Acanthamoeba spp. commonly cause Acanthamoeba keratitis which is typically associated with the wear of contact lenses. Therefore, finding an economic, efficient, and safe therapy of natural origin is of outmost importance. This study examined the in vitro lethal potential of ethyl acetate and methanol extracts of Helianthemum lippii (L.) (sun roses) against Acanthamoeba castellanii cysts isolated from patients with amoebic keratitis. Both extracts proved to be potent as regard to their lethal effects on A. castellanii cysts with comparable results to chlorhexidine. The ethyl acetate was more promising with cumulative lethality. It showed a highly significant lethal percentage along the duration of treatment. The analysis of the more potent ethyl acetate extract revealed the presence of 2.96 mg/100 g of total phenolics, 0.289 mg/100 ml of total flavonoids and 37 mg/100 mg of total tannins which highlighted their phytomedicinal role.

Development of Calculating System of Solids Level to Harvest High Solids Potato (Solanum tuberosum L.)

  • Jung, Jae-Youn;Suh, Sang-Gon
    • 원예과학기술지
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    • 제31권1호
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    • pp.103-109
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    • 2013
  • Estimating the high tuber solids needs a simulation system on potato growth, and its development should be obtained by using agricultural elements which analyze the relationship between crop growth and agricultural factors. An accurate simulation to predict solids level against climatic change employs a calculation of in vivo energy consumption and bias for growth and induction shape in a slight environmental adaptation. So, to calculate in vivo energy consumption, this study took a concept of estimate of the amount of basal metabolism in each tuber. In the validation experiments, the results of measuring solid accumulation of potatoes harvested at dates suggested by simulation agreed with the actual measured values in each regional field during the growth period of years from 2006 till 2010. The mean values of tuber solids level and inter-annual level variation in validation experiments were predicted well by the simulation model. And also, the results of validation experiments represent that concentration of tuber solids were due mainly to the duration of sunshine, above 190 hours per a month, and the cumulative amount of radiation, above 2,200 $MJ{\cdot}m^{-2}$, of the effective growth period.

Risk Assessment for Toluene Diisocyanate and Respiratory Disease Human Studies

  • PARK, Robert M.
    • Safety and Health at Work
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    • 제12권2호
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    • pp.174-183
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    • 2021
  • Background: Toluene diisocyanate (TDI) is a highly reactive chemical that causes sensitization and has also been associated with increased lung cancer. A risk assessment was conducted based on occupational epidemiologic estimates for several health outcomes. Methods: Exposure and outcome details were extracted from published studies and a NIOSH Health Hazard Evaluation for new onset asthma, pulmonary function measurements, symptom prevalence, and mortality from lung cancer and respiratory disease. Summary exposure-response estimates were calculated taking into account relative precision and possible survivor selection effects. Attributable incidence of sensitization was estimated as were annual proportional losses of pulmonary function. Excess lifetime risks and benchmark doses were calculated. Results: Respiratory outcomes exhibited strong survivor bias. Asthma/sensitization exposure response decreased with increasing facility-average TDI air concentration as did TDI-associated pulmonary impairment. In a mortality cohort where mean employment duration was less than 1 year, survivor bias pre-empted estimation of lung cancer and respiratory disease exposure response. Conclusion: Controlling for survivor bias and assuming a linear dose-response with facility-average TDI concentrations, excess lifetime risks exceeding one per thousand occurred at about 2 ppt TDI for sensitization and respiratory impairment. Under alternate assumptions regarding stationary and cumulative effects, one per thousand excess risks were estimated at TDI concentrations of 10 - 30 ppt. The unexplained reported excess mortality from lung cancer and other lung diseases, if attributable to TDI or associated emissions, could represent a lifetime risk comparable to that of sensitization.

소아 Henoch-$Sch{\ddot{o}}nlein$ purpura에서 스테로이드 치료 기간에 따른 임상적 결과의 비교 (Comparison of Clinical Outcome According to the Duration of Corticosteroid Therapy in Childhood Henoch-$Sch{\ddot{o}}nlein$ Purpura: a Bicentric Study)

  • 이수진;신재일;이종국;김기혁
    • Childhood Kidney Diseases
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    • 제12권2호
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    • pp.170-177
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    • 2008
  • 목 적 : Henoch-$Sch{\ddot{o}}nlein$ purpura (HSP) 환아에서 스테로이드 치료 기간에 따른 HSP의 재발이나 신장염 발생 빈도의 차이를 보기 위하여 본 연구를 시행하였다. 방 법: 일산에 위치한 두 종합 병원에 2000년부터 2003년까지 HSP로 진단 받은 186명 (평균 연령 6.3${\pm}$2.5 세, 남:여 = 104:82)의 환아 들에서 후향적 분석을 시행 하였다. 스테로이드 치료기간에 따른 예후의 차이를 보기 위하여 A 병원에서는 복통 및 관절통 증상이 경한 경우에는 경구 프레드니솔론을 투여 하였으며 복통 및 관절통이 심한 경우에는 정맥 내 덱사메타손을 투여 후에 경구 프레드니솔론을 복용하는 방법으로 치료를 시행하였는데 연구 전에 미리 계획한 대로 증상의 기간과 경중에 상관 없이 스테로이드 치료 기간은 최소 2주 이상 유지하였다. (A군, 94명) B 병원에서는 복통 및 관절통이 경한 경우에는 스테로이드제재 복용을 하지 않았으며, 심한 복통 및 관절통을 동반하는 경우 경구 프레드니솔론을 복용 하도록 하였으며 증상이 소실되면 즉시 용량을 감량하여 끊도록 하였다. (B군, 92명) 결 과 : 두 그룹간의 연령, 성별, 체중, 백혈구, 적혈구, 혈색소, 혈소판, 혈장 내 단백질, 알부민 수치는 통계적으로 차이가 없었다. 또한 복통(45%vs. 50%, P=0.557) 혹은 관절통(61% vs. 61%, P=1.0)의 발생 빈도도 두 군간에 차이가 없는 것으로 나타났다. 그러나 스테로이드 치료의 기간은 A군에서 B군 보다 길었으며(21.8${\pm}$8.4 vs. 6.1${\pm}$7.4 days, P<0.0001), 프레드니솔론의 누적 용량 또한 A군에서 높았다(20.2${\pm}$11.2 vs. 4.9${\pm}$5.9 mg, P<0.0001). 신장염의 발생은 A군에서 높게 나타났으며(23% vs. 10%, P=0.017), 반면에 재발률은 B군에서 높게 나타났다(10% vs 23%, P=0.017). 결 론 : 스테로이드의 사용 기간이 HSP 환자군의 신장 침범 발생률에 영향을 주지 못하였다. 그러므로 HSP 환아의 치료에서 스테로이드는 선별적으로 사용하여야 하며, 급성 증상이 조절되고 나면 즉시 용량을 줄여서 복용을 중단하는 것이 좋을 것으로 생각된다.

실지진하중의 액상화 발생특성에 기초한 액상화 상세평가법 (A New Detailed Assessment for Liquefaction Potential Based on the Liquefaction Driving Effect of the Real Earthquake Motion)

  • 최재순;강한수;김수일
    • 한국지반공학회논문집
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    • 제20권5호
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    • pp.145-159
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    • 2004
  • 본 연구에서는 지진시 지반의 안정성 평가시, 진동시험에 기초하여 액상화 발생가능성 여부를 판정하는 상세평가법을 개발하였다. 개발된 평가법에서는 기존의 평가법이 지진을 단순히 정현하중화하는 등가전단응력개념에 기초한점과는 달리, 지진의 최대가속도, 유효지속시간, 지진형태, 그리고 지진규모 등 다양한 지진영향인자가 고려될 수 있도록 실지진기록 입력의 지반응답해석을 포함하도록 하였다. 지반의 고유한 저항특성을 응력-변형률 시험 결과로부터 액상화 전환시점까지의 누적 소성 전단변형률로 하였으며 이와 연계하여 지진의 액상화 발생특성을 지반응답해석을 통해 획득 가능한 전단변형률 시간이력곡선에 기초하도록 하였다. 이때, 액상화를 유발시키는 실지진기록의 특성분석을 위해 실지진하중 재하의 진동삼축시험을 수행하였다. 시험결과, 충격형 지진인 경우, 지진기록의 최대하중이 재하된 직후, 과잉간극수압이 급진적으로 발전하며 액상화가 발생하는 것으로 나타났으며 진동형 지진의 경우에는 최대하중이 재하된 경우, 눈에 띄는 과잉간극수압의 변화가 관찰되었으며 이후, 일정수준 이상의 큰 하중재하시 액상화가 발생하였다. 이로부터 액상화 발생에 가장 큰 영향인자는 최대하중인 것을 알 수 있었으며 진동형 지진형태의 경우, 일정수준 이상의 후속하중에 대한 고려가 필요함을 알 수 있었다. 이상의 결과로부터 본 평가법에서는 우선적으로 충격형 지진에 한하여 사용할 것을 제안하며 이때, 최대 전단변형률까지의 시간이력곡선으로부터 소성 전단변형률을 누적계산하여 이를 해당입력지진의 액상화 발생특성치로 정하였다. 기존의 등가응력개념에 기초한 상세평가법과의 비교를 통한 타당성 분석결과, 본 평가법은 기존의 상세평가법보다 유효응력경로 및 응력-변형률 상관곡선 등 실제적인 지반거동변화에 관한 진동시험결과에 기초하여 지반의 고유특성을 결정하고 지반응답해석을 통해 증폭현상을 포함한 지반 내 지진거동변화와 지진시간이력이 보유하고 있는 지진특성을 충분히 반영하고 있으므로 신뢰성 높은 액상화 상세평가가 가능할 것으로 판단된다.

신품종 '만풍배' 유목의 수형별 수체 생육특성과 생산성 비교 (Comparision of Growth Characteristics and Productivity of Young Trees of a New Cultivar 'Manpungbae' Trained to Trellis Systems)

  • 최장전;최진호;한점화;임순희;정석규;최현석
    • 원예과학기술지
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    • 제35권4호
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    • pp.393-401
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    • 2017
  • 최근 국내에 상업적으로 유통되고 있는 '만풍배' 배(Pyrus pyrifolia L.)나무 1년생을 재식(2001년)하여 정식 8년차까지 4가지 수형(Y자형, Y-II형, 평덕형, 평덕배상형)을 적용하여 남부지방에 적합한 수형을 제시하고자 본 시험을 수행하였다. Y자형과 평덕형은 수관점유율이 높게 형성되었고 8년차에는 70-80%의 점유율을 보였다. 8년간 주당 누적수량은 소식이면서 주지가 다른 수형보다 1개 더 많은 평덕배상형에서 가장 높았다. 재식 5년차와 8년차의 누적 수량이용효율은 Y-II형과 평덕형에서 높게 나타났다. 8년간 ha당 누적수량은 Y자형과 평덕형이 각각 103톤과 101톤으로 Y-II형과 평덕배상형보다 2배 가까이 높았다. 재식 8년차에 평덕형은 평균과중과 과육당도를 증가시켰고 순소득도 가장 높았다. Y자형과 평덕배상형은 전정량 증가에 의한 노동량 및 시간이 증가하여 생산성이 낮은 수형으로 평가되었다.

Controlling Factors of Feed Intake and Salivary Secretion in Goats Fed on Dry Forage

  • Sunagawa, K.;Ooshiro, T.;Nakamura, N.;Nagamine, I.;Shiroma, S.;Shinjo, A.
    • Asian-Australasian Journal of Animal Sciences
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    • 제18권10호
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    • pp.1414-1420
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    • 2005
  • The purpose of this research was to determine whether or not feeding induced hypovolemia (decreases in plasma volume) and decreases in plasma bicarbonate concentration caused by loss of $NaHCO_3$ from the blood, act to suppress feed intake and saliva secretion volumes during the initial stages of feeding in goats fed on dry forage. The animals were fed twice a day at 10:30 and at 16:00 for 2 h each time. Prior to the morning feeding, the collected saliva (3-5 kg) was infused into the rumen. During the morning 2 h feeding period (10:30 to 12:30), the animals were fed 2-3 kg of roughly crushed alfalfa hay cubes. At 16:00, the animals were fed again with 0.8 kg of alfalfa hay cubes, 200 g of commercial ground concentrate and 20 g of sodium bicarbonate. In order to compensate for water or $NaHCO_3$ lost through saliva during initial stages of feeding, a 3 h intravenous infusion (17-19 ml/min) of artificial mixed saliva (ASI) or mannitol solution (MI) was begun 1 h prior to the morning feeding and continued until the conclusion of the 2 h feeding period. The physiological state of the goats in the present experiment remained unchanged after parotid gland fistulation. Circulating plasma volume decreases caused by feeding (estimated by increases in plasma total protein concentration) were significantly suppressed by the ASI and MI treatments. During the first 1 h of the 2 h feeding period, plasma osmolality in the ASI treatment was the same as the NI (non-infusion control) treatment, while plasma osmolality in the MI treatment was significantly higher. In comparison to the NI treatment, cumulative feed intake levels for the duration of the 2 h feeding period in the ASI and MI treatments increased markedly by 56.6 and 88.3%, respectively. On the other hand, unilateral cumulative parotid saliva secretion volume following the termination of the 2 h feeding period in the ASI treatment was 50.7% higher than that in the NI treatment. MI treatment showed the same level as the NI treatment. The results of the present experiment proved that the humoral factors involved in the suppression of feeding and saliva secretion during the initial stages of feeding in goats fed on dry forage, are feeding induced hypovolemia and decrease in plasma $HCO_3^-$ concentration caused by loss of $NaHCO_3$ from the blood.