• 제목/요약/키워드: cross-over studies

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The Role of Milk Products in Metabolic Health and Weight Management

  • Zemel, Michael B.
    • Journal of Dairy Science and Biotechnology
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    • 제28권1호
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    • pp.17-28
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    • 2010
  • A substantial body of evidence has emerged over the last decade in support of the novel concept that dietary calcium and dairy foods play an important role in regulating energy metabolism and thereby promote healthy weight management and reduce obesity risk. This concept has been demonstrated in experimental animals studies, cross-sectional and prospective population studies and a number of randomized clinical trials. Notably, the effects of dairy foods in weight management are more consistent than the effects of supplemental calcium across clinical trials, and calcium per se is responsible for approximately 40-50% of the effects of dairy. The calcium component is only effective in individuals with chronically low calcium intake, as it serves to prevent the endocrine response to low calcium diets which otherwise favors adipocyte energy storage; calcium also serves to promote energy loss via formation of calcium soaps in the gastrointestinal tract and thereby reduce fat absorption. The calcium-independent anti-obesity bioactivity of dairy resides primarily in whey. The key components identified to date are leucine and bioactive peptides resulting from whey protein digestion. The high concentration of leucine in whey stimulates a repartitioning of dietary energy from adipose tissue to skeletal muscle where it provides the energy required for leucine-stimulated protein synthesis, resulting in increased loss of adipose tissue and preservation of skeletal muscle mass during weight loss. Finally, dairy rich diets suppress the oxidative and inflammatory responses to obesity and thereby attenuate the diabetes and cardiovascular disease risk associated with obesity.

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Identifying Effective Dispute Resolution Mechanisms for Intellectual Property Disputes in the International Context

  • Lee, Ju-Yeon
    • 한국중재학회지:중재연구
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    • 제25권3호
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    • pp.155-184
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    • 2015
  • This paper addresses the question of what kinds of dispute resolution choices can effectively handle complex intellectual property disputes, given the rising importance of IP, the increasing frequency and complexity of IP disputes, and the lack of research on dispute resolution strategies. For this analysis, the study adopted the analytic hierarchy process approach, which covers complex, multi-criteria decision problems, to quantify the expert's judgments on IP dispute resolution choice. Its results show that the effectiveness of resolution methods differs, depending on the type of IP dispute classified into seven issues, which are (i) requirement for validity of IP right, (ii) range and duration of IP right, (iii) transfer of IP right, (iv) licensing, (v) use of IP right, (vi) declaration of IP infringement, and (vii) estimation of damage. The disputes over IPR ownership and IP infringement remain challenging issues in due to strong requirement of the cross-border enforcement. Alternative dispute resolution (ADR), especially arbitration, is determined to be a more effective method to deal with international IP disputes, but various advanced types of ADR techniques should be further developed to deal with the increasing complexity of IP disputes.

향기요법이 간호대학생의 월경 곤란증, 월경통, 불안 및 우울에 미치는 효과 (The Effects of Aromatherapy on Dysmenorrhea, Menstrual Pain, Anxiety, and Depression in Nursing Students)

  • 서지영;김미예
    • 성인간호학회지
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    • 제20권5호
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    • pp.756-764
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    • 2008
  • Purpose: The purpose of this study was to examine the effects of aromatherapy on dysmenorrhea, menstrual pain, anxiety, and depression in female college students. Methods: A two-group cross-over design was used. The sample included a total of 20 female students who were enrolled in a 3 year nursing program. The treatments(aroma essential oil inhalation and the placebo inhalation) were given using a necklace. The data were analyzed by $x^2$-test, paired t-test, and Mann-Whitney test using SPSS/WIN 12.0 program. Results: The level of dysmenorrhea after the aroma treatment was not significantly different from the dysmenorrhea levels at pre-test and after the post-placebo treatment. The menstrual pain, anxiety and depression significantly improved after the aroma treatment. However, the levels of pain, anxiety, and depression after the aroma treatment were not significantly different from those after the placebo treatment. Conclusion: Aroma inhalation may be a effective in managing menstrual pain, anxiety, and depression. In order to further clarify the effect of aroma treatment on discomfort during menstruation, replication studies are necessary. Future studies need to examine the effects of different types of essential oils, administrating methods, and the lasting time of aroma treatment effect.

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국내 자동차산업의 근골격계질환 실태에 관한 연구 (A Study of Musculoskeletal Disorders at Automobile Industries in Korea)

  • 김철홍
    • 산업경영시스템학회지
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    • 제24권67호
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    • pp.1-10
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    • 2001
  • A series of studies with collaboration of university, research institute, and labor union were conducted to examine the situation and severity of work-related musculoskeletal disorders (MSDs) at an automobile company which is one of the three major car companies in Korea. As the first part of the study, a questionnaire survey was conducted on 4,000 employees at 2 different assembly sites and A/S centers over the country. The questionnaire was consisted of three parts; symptom survey, work environment information, and labor intensity survey. Among 4,000 questionnaires, 2,643 responses were considered for analysis. The result showed that 68.5% of the respondents complained pains on at least one part of the body and 48.8% on at least two parts of the body. After cross-sectional analysis of various information and risk factors such as severity of symptom, duration and frequency of pain, 31.5% of respondents were considered as at high risk of having MSDs. This high-risk rate showed similar result when compared with previous studies conducted at various manufacturing industries in Korea. Also the analysis of the work environment and job intensity survey supported the high-risk rate of MSDs.

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ASEAN 국가들의 외국중재판정에 관한 승인 및 집행 - 말레이시아·싱가포르·인도네시아의 법제 및 판례를 중심으로 - (Recognition and Enforcement of Foreign Arbitration Awards in ASEAN)

  • 김영주
    • 한국중재학회지:중재연구
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    • 제25권2호
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    • pp.19-47
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    • 2015
  • International arbitration is an increasingly popular means of alternative dispute resolution for cross-border commercial transactions. The primary advantage of international arbitration over court litigation is enforceability. An international arbitration award is enforceable in most countries in the world. Especially, statistics indicate of ASEAN such as Malaysia and Singapore that the vast majority of defeated companies comply with the terms of international arbitral awards against them or settle soon after the award is rendered. Unlike Malaysia and Singapore, in Indonesia, there are several grounds for refusal of enforcement of an award including where both the nature of the dispute and the agreement to arbitrate do not meet the requirements set out in the Arbitration Law. Because Indonesia does not acknowledge decisions of foreign courts, theoretically they could enforce an international arbitral award which was set aside by the court in the seat of arbitration. This paper introduces the legal system and cases of recognition and enforcement of foreign arbitration awards in ASEAN, especially Malaysia, Singapore, and Indonesia. Secondly, by comparing their law and cases, the paper emphasized the international suitability and global fitness in involved in recognition and enforcement of foreign arbitration awards.

"A Very Sudden Thing": Recapturing Cold War History in Philip Roth's American Pastoral

  • Lew, Seunggu
    • 영미문화
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    • 제10권2호
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    • pp.49-72
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    • 2010
  • As the first of Philip Roth's recent series of novels that delve into American Cold War history deeply entwined with the post-war Jewish American experience, American Pastoral traces the tragic fall of a third-generation Jewish American named Seymour "Swede" Levov, whose dream of complete assimilation to the post-ethnic American paradise is irrecoverably disrupted when his young daughter blows up the local post office to protest against the Vietnam War. This essay proposes to examine Swede Levov's interrupted pursuit of the American dream by locating it within specific Cold War contexts and national imaginaries propagated particularly during the years from John F. Kennedy to Lyndon B. Johnson. In so doing, I will argue that Roth presents a paradoxical vision of Jewish American identity that could be acquired by performing perpetual self-effacement and submergence into the non-place of anonymity and doubleness, a mythic location of the post-ethnic Cold War American family. Levov's life becomes true part of the mythic narrative of American history when he realizes that his life, just like the nation's history, is a series of temporalities radically discontinued without any manageable detour ot divine bypass to cross over. Rather than indicating Roth's retraction from the postmodern understanding of subjectivity, the novel's historical realism, I will argue, serves to illuminate the postmodern conditions of American Cold War history and ethnic identity.

Effect of Masticating Chewing Gum on the Balance of Stroke Patients

  • Gim, Mina;Choi, Junghyun
    • 국제물리치료학회지
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    • 제12권2호
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    • pp.2370-2374
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    • 2021
  • Background: Masticating is an activity that is free from temporal or spatial constraints, with an advantage that it can be combined easily with other treatment methods. While several studies have reported a positive effect of the intervention of chewing using the jaw on postural stability, only a few studies were conducted on stroke patients. Objectives: To investigated the effects of masticating chewing gum on the static and dynamic balancing of stroke patients. Design: Randomized cross-over study design. Methods: Nineteen stroke patients were randomly assigned to the chewing group or control group. BT4 was used to measure the static and dynamic balancing abilities. Pre-test measurements were taken before mastication of chewing gum, and post-test measurements were taken after 2 days. The stroke patients in the chewing group were guided to sit on a chair and chew gum for 3 min, and their balancing abilities were simultaneously measured. The balancing abilities of the control group patients were measured while they sat at rest without masticating chewing gum. Results: The chewing group showed significant increases in the measures of static balance (i.e., C90 area, trace length, X mean, and Y mean). In the between-group comparison, the measures of static balance were significantly higher in the chewing group than in the control group. Conclusion: These findings suggest that masticating chewing gum enhanced the static balancing ability of stroke patients. Thus, gum chewing should be considered a viable clinical intervention to control posture in stroke patients.

Intellectual Capital and Innovation Capability: A Strategy for Achieving Competitive Advantage

  • OYELAKIN, Oyekunle;ABBA, Maryam Tijjani;ADAMU, Ahmed;BABAN-MAIRAM, Munir;NA'ANMAN, Sallah Boniface;FAKAH, Henrietta
    • 4차산업연구
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    • 제2권2호
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    • pp.11-23
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    • 2022
  • Purpose - The ability to meet the high demand for education in Nigeria is lacking, making the region remain backwards in education. Given this reason, the study investigates the role of innovation capability in the relationship between intellectual capital and competitive advantage in tertiary institutions in Nigeria. Research design, data, and methodology - The study is cross-sectional research, a total of 427 questionnaires were administered to respondents. The study distributed its questionnaire across 12 faculties at the University of Ibadan using a random sampling technique. Data were analyzed using ADANCO 2.1.1. Result - The study reveals that human capital, structural capital, relational capital, and innovation capability positively affect competitive advantage. Innovation capability mediates the relationship between human capital and relational capital. However, structural capital was not mediated by innovation capability. Conclusion - The study concludes that intellectual capitals and innovation capability are crucial to maintaining a competitive advantage over their peers. Achieving more significant success in the variables mentioned earlier will help Nigeria's tertiary institutions compete locally and internationally.

Monitoring changes in the genetic structure of Brown Tsaiya duck selected for feeding efficiency by microsatellite markers

  • Yi-Ying Chang;Hsiu-Chou Liu;Chih-Feng Chen
    • Animal Bioscience
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    • 제36권3호
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    • pp.417-428
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    • 2023
  • Objective: Few studies have genetically monitored chickens over time, and no research has been conducted on ducks. To ensure the sustainable management of key duck breeds, we used microsatellite markers to monitor Brown Tsaiya ducks over time genetically. Methods: The second, fourth, sixth to eighth generations of the Brown Tsaiya duck selected for feeding efficiency and control lines were included in this study to investigate the genetic variations, effective population size, population structure and the differentiation between populations over time with 11 microsatellite markers derived from Brown Tsaiya duck. Results: The results showed there were a slight decrease in the genetic variations and an increase in within-population inbreeding coefficient (FIS) in both lines, but no consistent increase in FIS was observed in each line. The effective population size in the second and eighth generations was 27.2 for the selected line and 23.9 for the control line. The change in allele richness showed a downward trend over time, and the selected line was slightly lower than the control line in each generation. The number of private alleles (Np) in the selected line were higher than in the control line. Moderate differentiation was observed between the second and eighth generations in the selected line (FST = 0.0510) and the control line (FST = 0.0606). Overall, differentiation tended to increase with each generation, but genetic variation and structure did not change considerably after six generations in the two lines. Conclusion: This study provides a reference for poultry conservation and helps to implement cross-generation genetic monitoring and breeding plans in other duck breeds or lines to promote sustainable management.

A Declaration of Love all the Same: Chicago and Modern Boy

  • Lee, Yujung
    • 비교문화연구
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    • 제20권
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    • pp.241-274
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    • 2010
  • Due to the remarkable changes in the early twentieth century, the new invention and technology impacted peoples' everyday lives and people started to use the word, modern, to apply specifically to what pertained to present times and to designate a movement in what was new and not old-fashioned-a condition of newness. In the present day, however, the fantastic cultural changes of a century ago have now become commonplace, and what was once considered radically new is no longer a reason to marvel. This paper considers what it mean to be modern, once the new is no longer new. This question seems to remain as complicated and inappropriate to ponder because the consideration and impact of modernity cannot simply end with the end of an era. This paper investigates how the interconnected nature of popular culture provides apt illustrations to reveal the ambivalent nature of modernity and postmodernity. In doing so, first of all, this paper pays attentions to the notion of modernity and popular culture which emerged together in the early twentieth century when technology and mass consumer culture were promoted over the world. Also, it examines how popular culture represents a complex of mutually-interdependent perspectives and values that influence society and its institutions in various ways as the image of modernity continues to build in a postmodern era. That is, popular culture is identified as a large amount of intertextuality or collective experiences due to its intermingling of complementary distribution sources and techonology. Thus, this paper explores that popular culture devotes itself other images or narratives instead of referring to the real world and its output revisits the contemporary or past times in other places, being a means to produce and reproduce the accumulated images of the modern which shapes ceaseless simulacra of modernity over complexities of modernity. In order to find a critical juncture of the complex networks of modernity and popular culture, this paper considers two places, Chicago and Gyeongsung in the 1920s and 1930s in which the rapid modern experience took place and the modern movement forced the two societies to join the mass consumer culture whether willingly or not. Next, this paper considers two movies released in 2002 and 2008 that exemplify the complexities of modernity in Chicago and Gyeongung of the 1920s and 30s: Chicago and Modern Boy. Both films have common themes of the 1920s and 30s such as violence, adultery, femme fatal, and criminal themes with the forms of musical, dance, drama, and romance. Through the textual analysis of both Chicago and Modern Boy, two films are compared in observing the similar and different ways in which two films deal with the theme of modernity when they are represented from the contemporary perspectives. More specifically, this paper questions how modernity is present in contemporary cultural forms such as commercial and hybrid genre films; and how these movies create a new image of modern by embodying the double coding. Ultimately, this paper aims at realizing the paradox of double edged modernity and its ongoing discourse that controls people's consciousness through the medium of popular culture.