• Title/Summary/Keyword: cross-modification

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Cross-cultural Validation of Instruments Measuring Health Beliefs about Colorectal Cancer Screening among Korean Americans

  • Lee, Shin-Young;Lee, Eunice E.
    • Journal of Korean Academy of Nursing
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    • v.45 no.1
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    • pp.129-138
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    • 2015
  • Purpose: The purpose of this study was to report the instrument modification and validation processes to make existing health belief model scales culturally appropriate for Korean Americans (KAs) regarding colorectal cancer (CRC) screening utilization. Methods: Instrument translation, individual interviews using cognitive interviewing, and expert reviews were conducted during the instrument modification phase, and a pilot test and a cross-sectional survey were conducted during the instrument validation phase. Data analyses of the cross-sectional survey included internal consistency and construct validity using exploratory and confirmatory factor analysis. Results: The main issues identified during the instrument modification phase were (a) cultural and linguistic translation issues and (b) newly developed items reflecting Korean cultural barriers. Cross-sectional survey analyses during the instrument validation phase revealed that all scales demonstrate good internal consistency reliability (Cronbach's alpha=.72~.88). Exploratory factor analysis showed that susceptibility and severity loaded on the same factor, which may indicate a threat variable. Items with low factor loadings in the confirmatory factor analysis may relate to (a) lack of knowledge about fecal occult blood testing and (b) multiple dimensions of the subscales. Conclusion: Methodological, sequential processes of instrument modification and validation, including translation, individual interviews, expert reviews, pilot testing and a cross-sectional survey, were provided in this study. The findings indicate that existing instruments need to be examined for CRC screening research involving KAs.

Hydrophobic modification of PVDF hollow fiber membranes using polydimethylsiloxane for VMD process

  • Cui, Zhaoliang;Tong, Daqing;Li, Xue;Wang, Xiaozu;Wang, Zhaohui
    • Membrane and Water Treatment
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    • v.10 no.4
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    • pp.251-257
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    • 2019
  • Fabricating hydrophobic porous membrane is important for exploring the applications of membrane distillation (MD). In the present paper, poly(vinylidene fluoride) (PVDF) hollow fiber membrane was modified by coating polydimethylsiloxane (PDMS) on its surface. The effects of PDMS concentration, cross-linking temperature and cross-linking time on the performance of the composite membranes in a vacuum membrane distillation (VMD) process were investigated. It was found that the hydrophobicity and the VMD performance of the PVDF hollow fiber membrane were obviously improved by coating PDMS. The optimal PDMS concentration, cross-linking temperature and cross-linking time were 0.5 wt%, $80^{\circ}C$, and 9 hr, respectively.

The Optimum Modification of Dynamic Characteristics of Stiffened Plate Structure Including the Number of Stiffener (보강재의 수를 포함한 보강판 구조물의 동특성의 최적변경)

  • 박성현;고재용
    • Journal of the Korean Institute of Navigation
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    • v.25 no.4
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    • pp.461-469
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    • 2001
  • The purpose of this paper is the optimum modification of dynamic characteristics of stiffened plate structure including the number of stiffener. This paper shows the optimum structural modification method by dynamic sensitivity analysis and quasi-least squares method and considers it's validity. In the method of the optimization, finite element method, sensitivity analysis and optimum structural modification method are used. The change of natural frequency and total weight are made to be an objective function. Thickness of plate, the number of stiffener and cross section moment of stiffener become a design variable. The dynamic characteristics of stiffened plate structure is analyzed using finite element method. Next, rate of change of dynamic characteristics by the change of design variable is calculated using the sensitivity analysis. Then, amount of change of design variable is calculated using optimum structural modification method. It is shown that the results are effective in the optimum modification for dynamic characteristics of the stiffened plate structure including the number of stiffener.

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Study on the Optimum Modification and Modal Analysis of Stiffened Plate of Ship Hull Structure (신체의 Stiffened Plate 구조물의 모우드해석과 최적변경법에 관한 연구)

  • 박성현;박석주;고재용
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2000.10b
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    • pp.51-58
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    • 2000
  • The purpose of this study is the optimum modification of dynamic characteristics of stiffened plate structure. In the method of the optimization ,finite element method (FEM), sensitivity analysis and optimum structural modification method are used. To begin with, using FEM, the dynamic characteristics of stiffened plate structure is analyzed. Next, rate of change of dynamic characteristic by the change of design variable is calculated using the sensitivity analysis. Then, amount of change of design variable is calculated using this sensitivity value and optimum structural modification method. The change of natural frequency is made to be an objective function. Thickness of plate and cross section moment become a design variable. It is shown that the results are effective in the optimum modification for dynamic characteristics of the stiffened plate structure.

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A Composite of Metal and Polymer Films: Thin Nickel Film Coated on a Polypropylene Film after Atmospheric Plasma Induced Surface Modification

  • Song, Ho-Shik;Choi, Jin-Moon;Kim, Tae-Wan
    • Transactions on Electrical and Electronic Materials
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    • v.12 no.3
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    • pp.110-114
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    • 2011
  • Polymeric films of high chemical stability and mechanical strength covered with a thin metallic film have been extensively used in various fields as electric and electronic materials. In this study, we have chosen polypropylene (PP) as the polymer due to its outstanding chemical resistance and good creep resistance. We coated thin nickel film on PP films by the electroless plating process. The surfaces of PP films were pre-treated and modified to increase the adhesion strength of metal layer on PP films, prior to the plating process, by an environment-friendly process with atmospheric plasma generated using dielectric barrier discharges in air. The surface morphologies of the PP films were observed before and after the surface modification process using a scanning electron microscope (SEM). The static contact angles were measured with deionized water droplets. The cross-sectional images of the PP films coated with thin metal film were taken with SEM to see the combined state between metallic and PP films. The adhesion strength of the metallic thin films on the PP films was confirmed by the thermal shock test and the cross-cutting and peel test. In conclusion, we made a composite material of metallic and polymeric films of high adhesion strength.

Investigation of Transglutaminase-Induced Peptide Cross-Linking by Matrix-Assisted Laser Desorption / Ionization Time-of-Flight Mass Spectrometry

  • 김희준;임효섭
    • Bulletin of the Korean Chemical Society
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    • v.20 no.11
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    • pp.1299-1302
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    • 1999
  • Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) was used to demonstrate cross-linking of peptides induced by transglutaminase. The presence of ε-( Υ-glutamyl)lysine isopeptide cross-link in the acid hydrolysate of the cross-linking reaction mixture was also demonstrated by MALDI-TOF-MS without prior separation. MALDI-TOF-MS quickly provided peptide mass maps after pronase digestion of the cross-linked peptide adduct, which enabled us to monitor the hydrolytic sequence. Pronase appears to preferentially hydrolyze peptide bonds distant from the cross-link before hydrolyzing peptide bonds around the cross-link. The results suggest that pronase digestion followed by MALDI-TOF-MS could be used for determination of amino acid sequence around a modification site.

Recent Advances in Polybenzimidazole (PBI)-based Polymer Electrolyte Membranes for High Temperature Fuel Cell Applications

  • Vijayakumar, Vijayalekshmi;Kim, Kihyun;Nam, Sang Yong
    • Applied Chemistry for Engineering
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    • v.30 no.6
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    • pp.643-651
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    • 2019
  • Polybenzimidazole (PBI), an engineering polymer with well-known excellent thermal, chemical and mechanical stabilities has been recognized as an alternative to high temperature polymer electrolyte membranes (HT-PEMs). This review focuses on recent advances made on the development of PBI-based HT-PEMs for fuel cell applications. PBI-based membranes discussed were prepared by various strategies such as structural modification, cross-linking, blending and organic-inorganic composites. In addition, intriguing properties of the PBI-based membranes as well as their fuel cell performances were highligted.

Enigma of Small Peptides Ubiquitin and SUMO in Plants

  • Seo, Hak Soo
    • Korean Journal of Breeding Science
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    • v.42 no.4
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    • pp.339-343
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    • 2010
  • Post-translational covalent modifications by small molecules or peptides remodel target proteins. One such modification, made by ubiquitin or small ubiquitin-related modifier (SUMO), is a rapidly expanding field in cell signaling pathways. Ubiquitin attachment controls the turnover and degradation of target proteins while SUMO conjugation regulates their activity and function. Recent studies report many examples of cross-talk between ubiquitin and SUMO pathways, indicating that the boundary is no longer clear. Here, we review recent progress concerning how ubiquitin and SUMO participate in new regulatory roles in plant cell, and how ubiquitination and sumoylation control plant growth and development.

Design and Analysis to aluminize Car Cross Beam for Small Passenger Car (소형 승용차용 카 크로스 빔의 알루미늄화를 위한 설계 및 해석)

  • Shin, Hyun-Woo;Park, Joon-Gyu;Kong, Moon-Kyu
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.12 no.2
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    • pp.91-99
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    • 2013
  • Car cross beam made by aluminium for new car is designed for the substitution of steel and it can be verified the performance by computer simulations. The parts of car cross beam are designed to replace steel parts according to their manufacturing processes. At the first stage, the weight of the aluminium car cross beam can be reduced to 75% by comparing with that of steel car cross beam. But NVH performance of the aluminium car cross beam becomes slightly insufficient as compared with that of steel car cross beam. Taguchi method is adopted to optimize the design variables affecting NVH characteristics of car cross beam. New car cross beam is designed at the second stage by using these analysis results. Weight reduction can be obtained to 31.7% by design modification and material change of car cross beam in comparison with the original steel one. NVH characteristics of aluminium car cross beam become on an equal level with the steel car cross beam. By side impact analysis results, new car cross beam has higher performance as compared with the steel car cross beam.

Development of Modification Coefficient for Nonlinear Single Degree of Freedom System Considering Plasticity Range for Structures Subjected to Blast Loads (폭발 하중을 받는 구조물의 소성 범위를 고려한 비선형 단자유도 시스템의 수정계수 개발)

  • Tae-Hun Lim;Seung-Hoon Lee;Han-Soo Kim
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.37 no.3
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    • pp.179-186
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    • 2024
  • In this paper, a modification coefficient for equivalent single degree of freedom (SDOF), considering the plasticity range of the member subjected to shock wave type of blast load, was developed. The modification coefficient for the equivalent SDOF was determined through comparison with the analysis of a multi-degree of freedom (MDOF) system. The parameters influencing the equivalent SDOF system analysis were chosen as the boundary conditions of the member and the ratio of the duration of blast load to the natural period of the member. The modification coefficient was calculated based on the elastic load-mass transformation factor. The modification coefficient curve was derived using an elliptical equation to ensure it exists between the upper and lower parameter bounds. Using the modification coefficient on examples with varying cross sections and boundary conditions reduced the SDOF analysis error rate from 15% to 3%. This study shows that using the modification coefficient significantly improves the accuracy of SDOF analysis. The modification coefficient proposed in this study can be used for blast analysis.