• Journal of Pharmaceutical Investigation
• /
• v.5 no.4
• /
• pp.32-37
• /
• 1975

The intentional test of the clinical test on the mouse, which are orally administered salicylamide combined with chlorpheniramine maleate were made by writhing syndrome method of 0.7% acetic acid-saline solution and following effects were found. 1) The cross-over test of writhing syndrome method have intention in case of three days rest after the first examination. 2) The most active rate of salicylamide by administration combined with chlorpheniramine maleate is salicylamide 20mg/kg: chlorpheniramine maleate 20mg/kg (1:1) 3) The most active range of chlorpheniramine maleate used for assistant action of salicylamide is $15mg/kg{\sim}20mg/kg$

• Korean Journal of Clinical Pharmacy
• /
• v.10 no.1
• /
• pp.19-24
• /
• 2000

The effect of cimetidine on the pbarmacokinetic parameters of cyclosporine (intravenous administration) were determined in 6 healthy volunteers (22-48 years old, 48-62 kg) by cross-over design. Cyclosporine and cyclosporine metabolites in whole blood were analysed by fluororescence polarization immunoassay (TDx-FLX). The blood concentrations of cyclosporine After pretreatment with cimetidine (200 mg bid, for 3days) were increased significantly at 8-12 hrs compared to the control (p<0.05). The ratios of blood concentrations of cyclosporine metabolites (M1, M17) to parent drug were decreased significantly at 8-12 hrs (p<0.05). Total body clearance (CL) was also decreased significantly (p<0.05), and area under the curve $(AUC,\%)$ was increased but not significant.

• The Journal of Asian Finance, Economics and Business
• /
• v.9 no.2
• /
• pp.113-120
• /
• 2022

The goal of this study is to see if there's a relationship between employees' ambidextrous behaviors and macro facilitators of organizational empowerment (such as control over workplace decisions, dynamic structural framework, and fluidity in information sharing) (exploration and exploitation). To acquire data, this study uses survey methods. A cross-sectional survey was done to collect information from academics at five large public sector universities in Pakistan's Balochistan province. Control over workplace decisions boosts academics' engagement in exploration and exploitation, while a dynamic structural framework merely increases their engagement in exploration, according to the findings based on data from 240 respondents (n = 240). The findings also show that information sharing flexibility has little effect on exploration and exploitation behaviors. In conclusion, the results of this study imply that organizational empowerment is critical for academics' ambidextrous behaviors to thrive. As a result, specific organizational facilitators of empowerment (such as control over workplace decisions and a dynamic structural framework) are advised in higher education institutions. This research is significant because it develops and tests a model that explains hitherto unexplored connections between macro facilitators of organizational empowerment and employees' ambidextrous behaviors. In addition, the research provides important insights for managerial practice and research.

• Structural Engineering and Mechanics
• /
• v.78 no.1
• /
• pp.87-102
• /
• 2021

Long span cross-rope suspension structure is an innovative structural system evolved from typical Cross-Rope Suspension (CRS) guyed tower, a type of supporting system with short span suspension cable supporting overhead power transmission lines. In mountainous areas, the span length of suspension cable was designed to be extended to hundreds or over one thousand meters, which is applicable for crossing deep valleys. Vortex Induced Vibration (VIV) of overhead power transmission lines was considered to be one of the major factors of its fatigue and service life. In this paper, VIV and its controlling by Stockbridge damper for long span CRS was discussed. Firstly, energy balance method and finite element method for assessing VIV of CRS were presented. An approach of establishing FE model of long span CRS structure with dampers was introduced. The effect of Stockbridge damper for overall vibration of CRS was compared in both theoretical and numerical approaches. Results indicated that vibration characteristics of conductor in long span CRS compared with traditional tower-line system. Secondly, analysis on long span CRS including Stockbridge damper showed additional dampers installed were essential for controlling maximum dynamic bending stresses of conductors at both ends. Moreover, factors, including configuration and mass of Stockbridge damper, span length of suspension cable and conductor and number of spans of conductor, were assessed for further discussion on VIV controlling of long span CRS.

• Journal of Korean Academy of Nursing
• /
• v.49 no.1
• /
• pp.69-79
• /
• 2019

Purpose: This study aimed to identify the directionality of the causal relationship and interaction between depression and amount of smoking over time in hardcore smokers using longitudinal descriptive analysis. Methods: Secondary data from the Korean Welfare Panel Study were analyzed using autoregressive cross-lagged modeling. Participants included 342 hardcore smokers who participated in the 8th to 11th waves of the panel study. Results: Analyses revealed that change(s) in depression levels according to time had a significant positive relationship with the total amount of smoking per day (${\beta}=.29$, ${\beta}=.19$, ${\beta}=.17$, p<.001), while change(s) in total amount of smoking per day according to time had a significant positive relationship with depression (${\beta}=.43$, ${\beta}=.50$, ${\beta}=.38$, p<.001). Analysis of the cross-lagged effect between depression and total amount of smoking per day showed that depression at one time point had a significantly positive relationship with the total amount of smoking per day at the next time point (${\beta}=.14$, ${\beta}=.13$, ${\beta}=.13$, p=.021), and that the total amount of smoking per day at one time point had a significant positive relationship with depression at the next time point (${\beta}=.04$, ${\beta}=.04$, ${\beta}=.03$, p=.044). Conclusion: The findings in the present study confirmed a cross-interaction between depression and total amount of smoking per day in hardcore smokers. The present findings could be used to develop appropriate smoking-related interventions.

• Fashion & Textile Research Journal
• /
• v.8 no.1
• /
• pp.55-63
• /
• 2006

The purpose of this study examines difference of cunsumer satisfaction by expected selection attribute of wedding dress and bride make-up. It is looking into influencing variables in consumer satisfaction, and is supplying real information to wedding market. The subjects of this study were 241 women getting married within one year of Daegu. The data were analyzed by using frequency, mean, the standard deviation, ANOVA, duncan test, correlation analysis, cross-analysis. Conclusion obtained from the results and discussions of the research are as follows: 1) In the attribution of expected selection according to occupation, blue-collar women are concerned about cost factor but they are low content with the perceptual satisfaction factor. 2) When selecting places for wedding dresses and wedding make-up, in the attribute of expected selection about the number of visiting the shop for wedding dresses and make-up, people who visit over 7 dress shops are highly interested in the appearance fancy degree, advertisements effect factors. But they are concerned with advertisements effect factor, cost factor in the perceptual satisfaction factor about wedding dress. Besides, the more they get chances to visit many dress shops, they are concerned with advertisements, cost factors, and satisfied with both the effect of advertisements and appearance factor degree in the attribution of expected selection about wedding make-up. 3) In the attribution of expected selection about the cost of wedding dresses and make-up, the lower the cost paid, people are interested in price factor. Furthermore, in the attribution of expected selection about the wedding dress and make-up cost, those who spent over 150 million Won are interested in quality, others influence factor, and the case of less than 120~150 million Won, people are highly interested in the appearance fancy degree, advertisements effect factor, and the women are satisfied with the advertisement effect factor in the perceptual satisfaction factor of wedding make-up.

• Journal of Crop Science and Biotechnology
• /
• v.11 no.2
• /
• pp.151-156
• /
• 2008

The objective of this study is to identify main-effect QTLs, epistatic QTLs, and the interactions between QTL and the environment associated with grain appearances of brown rice. A genetic linkage map was created with 172 DNA markers spanning 12 rice chromosomes based on 120 DH lines, which derived from a cross between 'Samgang'(Tongil) and 'Nagdong'(Japonica). One thousandgrain weight, length, width, length-to-width ratio, and thickness were evaluated regarding the DH population. Twenty independent QTLs and fourteen epistatic QTLs were identified in using CIM by two programs, known as WinQTLcart2.5 and QTLMAPPER. The QTLs of qgw9.1 in an interval of RM434-RM242 on chromosome 9 and qgw11.1 at a peak marker of RM287 on chromosome 11 for one thousand-grain weight, qgwi2.2 for grain width at a peak marker of RM450, qlw2.1 for length-to-width ratio flanked by RM492 and RM324, and qgt2.1 for thickness flanked by 2009 and RM492 on chromosome 2 were detected over two years, which can be considered as stable QTLs. The epistatic effect might be an important component for genetic basis of one thousand-grain weight and width. The main-effect QTLs of grain width and length to width ratio were easily influenced by environments.

• KDI Journal of Economic Policy
• /
• v.12 no.4
• /
• pp.21-46
• /
• 1990

This paper, a sequel to Yoo and Lee (1990), attempts to investigate the interindustry determinants of technical efficiency in Korea's manufacturing industries, and also to conduct an exploratory analysis on the stability of technical efficiency over time. The hypotheses set forth in this paper are most found in the existing literature on technical efficiency. They are, however, revised and shed a new light upon, whenever possible, to accommodate any Korea-specific conditions. The set of regressors used in the cross-sectional analysis are chosen and the hypotheses are posed in such a way that our result can be made comparable to those of similar studies conducted for the U.S. and Japan by Caves and Barton (1990) and Uekusa and Torii (1987), respectively. It is interesting to observe a certain degree of similarity as well as differentiation between the cross-section evidence on Korea's manufacturing industries and that on the U.S. and Japanese industries. As for the similarities, we can find positive and significant effects on technical efficiency of relative size of production and the extent of specialization in production, and negative and significant effect of the variations in capital-labor ratio within industries. The curvature influence of concentration ratio on technical efficiency is also confirmed in the Korean case. There are differences, too. We cannot find any significant effects of capital vintage, R&D and foreign competition on technical efficiency, all of which were shown to be robust determinants of technical efficiency in the U.S. case. We note, however, that the variables measuring capital vintage effect, R&D and the degree of foreign competition in Korean markets are suspected to suffer from serious measurement errors incurred in data collection and/or conversion of industrial classification system into the KSIC (Korea Standard Industrial Classification) system. Thus, we are reluctant to accept the findings on the effects of these variables as definitive conclusions on Korea's industrial organization. Another finding that interests us is that the cross-industry evidence becomes consistently strong when we use the efficiency estimates based on gross output instead of value added, which provides us with an ex post empirical criterion to choose an output measure between the two in estimating the production frontier. We also conduct exploratory analyses on the stability of the estimates of technical efficiency in Korea's manufacturing industries. Though the method of testing stability employed in this paper is never a complete one, we cannot find strong evidence that our efficiency estimates are stable over time. The outcome is both surprising and disappointing. We can also show that the instability of technical efficiency over time is partly explained by the way we constructed our measures of technical efficiency. To the extent that our efficiency estimates depend on the shape of the empirical distribution of plants in the input-output space, any movements of the production frontier over time are not reflected in the estimates, and possibilities exist of associating a higher level of technical efficiency with a downward movement of the production frontier over time, and so on. Thus, we find that efficiency measures that take into account not only the distributional changes, but also the shifts of the production frontier over time, increase the extent of stability, and are more appropriate for use in a dynamic context. The remaining portion of the instability of technical efficiency over time is not explained satisfactorily in this paper, and future research should address this question.

• Journal of Life Science
• /
• v.12 no.2
• /
• pp.213-218
• /
• 2002

The experiment was conducted to get basic information for cotton breeding program through four-variety diallel cross population. Additive, dominant, maternal, and reciprocal effect were observed significantly for days to maturity. Based on the Vr-Wr graphical analysis, the characters, number of bolls per plant, boll weight, seed and lint weight per boll, lint weight per boll, width of seed, 100-seed weight, days to flowering, and days to maturity were found to inherit incomplete dominance, and the characters of number of bolls per plant, width of seed, number of seeds per boll, and length of seed were assumed to inherit over dominance. The component of genetic variance analysis for boll weight, seed and lint weight per boll, lint weight per boll, number of seeds per boll, length of seed, and days to flowering showed that additive effects were higher than dominant effects. The narrow-sense heritability(h$_2$N) for boll weight, seed and lint weight per boll, lint weight per boll, days to flowering, and days to maturity showed high values as more than 43.19%. The estimate of broad-sense heritability(h$_2$B) value was higher than that of h$_2$N because of the low importance of dominance effects.

• Proceedings of the Korean Society for Information Management Conference
• /
• 2010.08a
• /
• pp.29-32
• /
• 2010

As a Korean national institute, KISTI has assigned and deposited DOIs to use Korean journals internationally as well as to enlarge the citation all over the world. In addition, KISTI has provided the service, Cited-by linking, which is to identify the citation among journals. In the paper, we would like to propose the way to expand the citation, finding the result of citation by using Cited-by linking based on DOIs in CrossRef for Scientific and technical journals deposited by KISTI.