• Title/Summary/Keyword: cross check

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Analytical Performance of Sensitivity and Specificity for Rapid Multiplex High Risk Human Papillomavirus Detection Kit: HPV ViroCheck (고위험군 HPV 검출을 위한 분석적 민감도와 특이도 성능평가)

  • Park, Sunyoung;Yoon, Hyeonseok;Bang, Hyeeun;Kim, Yeun;Choi, Seongkyung;Ahn, Sungwoo;Kim, Jungho;Lee, Suji;Yang, Ji Yeong;Lee, Dongsup
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.4
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    • pp.446-454
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    • 2017
  • Human papillomaviruses (HPVs) are major causes of cervical cancer. Sixteen high risk HPVs, including HPV 16, HPV 18, HPV31, HPV 33, HPV 35, HPV 39, HPV 45, HPV 51, HPV 52, HPV 53, HPV 56, HPV 58, HPV 59, HPV 66, HPV 68, and HPV 69 are found in cervical cancer. HPVs 16 and 18 are mainly presented in 70% of cervical cancer. Therefore, identifying the presence of these high-risk HPVs is crucial. The objective of this study is to establish the HPV ViroCheck for detecting 16 HR-HPVs and genotypes of HPVs 16 and 18, as well as to analyze the analytical performance of HPV ViroCheck. We performed the analytical sensitivity of HPV E6 / E7 genes of 16 high risk HPVs to confirm the limit of detection. Then, a cross reactivity of HPV ViroCheck with microorganisms and viruses related to the cervix were analyzed for analytical specificity. Analytical sensitivity of high risk HPV genotypes ranged from 1 to 100 copies when using cloned DNAs. The limit of detection was 10 cells for both SiHa and HeLa cells. Cervical-related microorganisms and viruses did not show cross-reactivity to HPV DNA. Moreover, the intra- and inter-assay coefficient variations (CVs) were below 5%. In conclusion, HPV Virocheck will be useful for the detection of 16 HR HPVs, as well as HPV 16 and HPV 18 genotypes rapidly.

The Effect of Turbulence Penetration on the Thermal Stratification Phenomenon Caused by Coolant Leaking in a T-Branch of Square Cross-Section

  • Choi, Young-Don;Hong, Seok-Woo;Park, Min-Soo
    • International Journal of Air-Conditioning and Refrigeration
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    • v.11 no.2
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    • pp.51-60
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    • 2003
  • In the nuclear power plant, emergency core coolant system (ECCS) is furnished at reactor coolant system (RCS) in order to cool down high temperature water in case of emergency. However, in this coolant system, thermal stratification phenomenon can occur due to coolant leaking in the check valve. The thermal stratification produces excessive thermal stresses at the pipe wall so as to yield thermal fatigue crack (TFC) accident. In the present study, effects of turbulence penetration on the thermal stratification into T-branches with square cross-section in the modeled ECCS are analysed numerically. Standard k-$\varepsilon$ model is employed to calculate the Reynolds stresses in momentum equations. Results show that the length and strength of thermal stratification are primarily affected by the leak flow rate of coolant and the Reynolds number of duct. Turbulence penetration into the T-branch of ECCS shows two counteracting effects on the thermal stratification. Heat transport by turbulence penetration from main duct to leaking flow region may enhance thermal stratification while the turbulent diffusion may weaken it.

Unsteady wind loading on a wall

  • Baker, C.J.
    • Wind and Structures
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    • v.4 no.5
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    • pp.413-440
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    • 2001
  • This paper presents an extensive analysis of unsteady wind loading data on a 18 m long and 2 m high wall in a rural environment, with the wind at a range of angles to the wall normal. The data is firstly analyzed using standard statistical techniques (moments of probability distributions, auto- and cross-correlations, auto- and cross-spectra etc.). The analysis is taken further using a variety of less conventional methods - conditional sampling, proper orthogonal decomposition and wavelet analysis. It is shown that, even though the geometry is simple, the nature of the unsteady flow is surprisingly complex. The fluctuating pressures on the front face of the wall are to a great extent caused by the turbulent fluctuations in the upstream flow, and reflect the oncoming flow structures. The results further suggest that there are distinct structures in the oncoming flow with a variety of scales, and that the second order quasi-steady approach can predict the pressure fluctuations quite well. The fluctuating pressures on the rear face are also influenced by the fluctuations in the oncoming turbulence, but also by unsteady fluctuations due to wake unsteadiness. These fluctuations have a greater temporal and spatial coherence than on the front face and the quasi-steady method over-predicts the extent of these fluctuations. Finally the results are used to check some assumptions made in the current UK wind loading code of practice.

A Study of Accuracy Improvement for Scattering Analysis of FMM Method (FMM 기법의 산란해석 정확도 향상 연구)

  • Kim, Young-joo;Cho, Young-Ki;Son, Hyun
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.12 no.6
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    • pp.972-982
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    • 2001
  • FMM(Fast Multipole Method) is suitable numerical method for radar cross section calculation of arbitrary large conducting bodies due to reduction of computation time. The accuracy of the numerical results, however, can influenced by selection of grouping method and segment length, in particular, far the case that cross section of the scatter is of the narrow width elliptical type. So, we describe the FMM method which can be deal effectively with such difficulties for both TM and TE polarization case. In order to check the present method the results are compared with those obtained by Method of Moments.

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A Study on a Radar Absorbing Structure for Aircraft Leading Edge Application

  • Baek, Sang Min;Lee, Won Jun;Joo, Young Sik
    • International Journal of Aeronautical and Space Sciences
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    • v.18 no.2
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    • pp.215-221
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    • 2017
  • An electromagnetic (EM) wave absorber reduces the possibility of radar detection by minimizing the radar cross section (RCS) of structures. In this study, a radar absorbing structure (RAS) was applied to the leading edge of a blended wing body aircraft to reduce RCS in X-band (8.2~12.4GHz) radar. The RAS was composed of a periodic pattern resistive sheet with conductive lossy material and glass-fiber/epoxy composite as a spacer. The applied RAS is a multifunctional composite structure which has both electromagnetic (EM) wave absorbing ability and load-bearing ability. A two dimensional unit absorber was designed first in a flat-plate shape, and then the fabricated leading edge structure incorporating the above RAS was investigated, using simulated and free-space measured reflection loss data from the flat-plate absorber. The leading edge was implemented on the aircraft, and its RCS was measured with respect to various azimuth angles in both polarizations (VV and HH). The RCS reduction effect of the RAS was evaluated in comparison with a leading edge of carbon fabric reinforced plastics (CFRP). The designed leading edge structure was examined through static structural analysis for various aircraft load cases to check structural integrity in terms of margin of safety. The mechanical and structural characteristics of CFRP, RAS and CFRP with RAM structures were also discussed in terms of their weight.

Validation Study of Korean Version of the Rothbart's Children's Behavior Questionnaire (한국판 Rothbart 유아용 기질 척도(Children's Behavior Questionnaire)의 타당화)

  • Lim, Ji-Young;Bae, Yun-Jin
    • Korean Journal of Human Ecology
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    • v.24 no.4
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    • pp.477-497
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    • 2015
  • The purpose of this study was to examine the psychometric property of the Children's Behavior Questionnaire(CBQ), including reliability, content validity, construct validity, cross validity, and concurrent validity with EAS(Emotionality, Activity, Sociability) scale. The CBQ is a caregiver report measure designed to provide a detailed assessment of temperament in children 3 to 7 years of age. In this study, two groups of participants were included to check cross validity. The first group of participants were 108 preschoolers, 3 to 7 years of age attending kindergartens or child care centers, and their mothers. The second group of participants were 168 preschoolers and their mothers. The CBQ subscales demonstrate adequate internal consistencies. Also, exploratory and confirmatory factor analyses of the CBQ scale reliably recover a three-factor solution indicating three broad dimension of temperament: extraversion/surgency, negative affectivity, and effortful control. Evidence for concurrent validity derives from results of correlation analysis with EAS scale.

Anatomical Characteristics of Bisected Compression Woods and Their Intervened Wood in a Stem of Pinus densiflora S. et Z. (소나무(Pinus densiflora S. et Z.)수간내(樹幹內)에 양분형성(兩分形成)된 압축이상재(壓縮異常材)와 그 사이에 존재(存在)하는 간재(間材)의 해부학적(解剖學的) 특성(特性))

  • Lee, Phil-Woo;Chung, Youn-Jib
    • Journal of the Korean Wood Science and Technology
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    • v.16 no.2
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    • pp.42-49
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    • 1988
  • Anatomical characteristics on abnormal type of bisected compression woods and light colored wood intervened between these dark colored compression woods on under part and their respective opposite woods on upper parts of cross section in Pinus densiflora S. et Z. stem were compared through optical microscopic investigation. and the obtained results were summarized as follows: 1. Tracheid length increased linearly as the number of rings from the pith increases in all investigated parts, but increasing tendency in tracheid length was similar within bisected two compression woods and their opposite woods. 2. Tracheids were the shortest in bisected two compression woods and tracheid length in intervened wood between these two compression woods was longer than in compression woods but shorter than in the opposite woods. 3. Bisected two compression woods and intervened wood between these two compression woods revealed similar features in tracheid transition from springwood to summerwood, intercellular space, tracheid entanglement, and cross sectional view of tracheid. but spiral check was observed only in these two compression woods, therefore the intervened wood between these two compression woods disclosed anatomical characteristics similar to, not typical of, compression woods.

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The Effect of Turbulence Penetration on the Thermal Stratification Phenomenon Caused by Leaking Flow in a T-Branch of Square Cross-Section (난류침투가 사각단면 T분기관 내 누설유동에 의해 발생한 열성층 현상에 미치는 영향)

  • 홍석우;최영돈;박민수
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.15 no.3
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    • pp.239-245
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    • 2003
  • In the nuclear power plant, emergency core coolant system (ECCS) is furnished at reactor coolant system (RCS) in order to cool down high temperature water in case of emergency. However, in this coolant system, thermal stratification phenomenon can occur due to coolant leaking in the check valve. The thermal stratification produces excessive thermal stresses at the pipe wall so as to yield thermal fatigue crack (TFC) accident. In the present study, effects of turbulence penetration on the thermal stratification into T-branches with square cross-section in the modeled ECCS are analysed numerically. $textsc{k}$-$\varepsilon$ model is employed to calculate the Reynolds stresses in momentum equations. Results show that the length and strength of thermal stratification are primarily affected by the leak flow rate of coolant and the Reynolds number of the main flow in the duct. Turbulence penetration into the T-branch of ECCS shows two counteracting effects on the thermal stratification. Heat transport by turbulence penetration from the main duct to leaking flow region may enhance thermal stratification while the turbulent diffusion may weaken it.

Design of a Dual-fed Microstrip Patch Antenna (이중급전 마이크로스트립 패치 안테나 설계)

  • Lee, Jong-Ig;Yeo, Junho;Kim, Gun-kyun;Rhee, Seung-Yeop
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2016.05a
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    • pp.79-80
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    • 2016
  • In this paper, we considered a design method for a microstrip patch antenna fed through two radiating edges by two feeding microstrip lines. Two feedlines are made to have a phase difference of 180 degree with each other in order to reduce cross-polarization level radiated from the antenna. The operation principle and design procedure for the considered antenna are explained using equivalent circuits. In order to check the validity of this study, the results for reflection coefficients of the antenna obtained by the proposed equivalent circuit method and the simulation using commercial antenna design tool are compared with each other.

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Research of Tan$\delta$ Measurement on Pole Transformers using DSP (DSP를 이용한 주상변압기 유전정접 측정기법 연구)

  • 김재철;이보호;김언석;최도혁;이수길
    • The Proceedings of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.11 no.2
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    • pp.110-118
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    • 1997
  • This paper describes the dissipation factor measuring techniques of insulating oil on operating pole transformers by using digital signal processor. After applying voltage to the condenser which is in¬stalled in a transformer, acquiring source voltage and current of condenser and using cross-correla¬tion techniques, we can check the dissipation factor of insulating oil. To improve measuring accuracy and the speed of process, we use hardware such as TMS320C31 DSP board and software such as cross -correlation techniques. We simulated the measuring accuracy and the degree of the noise effect of this new measuring techniques by using computer simulation, and compared the simplified measuring devices with Schering bridge on degraded insulating oil. The result showed that this measuring tech¬nique can be used as diagnostic method on the pole transformers.

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