• Nuclear Engineering and Technology
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• v.49 no.6
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• pp.1234-1239
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• 2017

Basic research on the accelerator-driven system is conducted by combining $^{235}U$-fueled and $^{232}Th$-loaded cores in the Kyoto University Critical Assembly with the pulsed neutron generator (14 MeV neutrons) and the proton beam accelerator (100 MeV protons with a heavy metal target). The results of experimental subcriticality are presented with a wide range of subcriticality level between near critical and 10,000 pcm, as obtained by the pulsed neutron source method, the Feynman-${\alpha}$ method, and the neutron source multiplication method.

• Journal of the Korean Society of Systems Engineering
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• v.17 no.2
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• pp.37-48
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• 2021

Improving the plant protection system against unforeseen changes/transients during operation is essential to maintain plant safety. Under this condition, it requires rapid and accurate signal processing. The use of an Intellectual Property (IP) core for floating point calculations for Safety Critical MMIS can make numerical computations easier and more precise, improving system accuracy. It can represent and manipulate rational numbers as well as a much broader range of values with dynamic range in nuclear power plant. Systems engineering approach (SE) is used through the development process, it helps to reduce complexity and avoid omissions and invalid assumptions as delivers a better understanding of the stakeholders needs. For the implementation on the FPGA target board, the 32-bit floating-point arithmetic with IEEE-754 standards has designed using Simulink model in Matlab for all operations of addition, subtraction, multiplication and division and VHDL code generated.

• Journal of Korean Critical Care Nursing
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• v.10 no.3
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• pp.1-8
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• 2017

Purpose : This study examined the status of critical care nursing education in bachelor of science in nursing (BSN) to suggest future directions. Methods : The target of the survey was 185 BSN programs that were certified by the Korean Accreditation Board of Nursing Education as of October 31, 2016. We structurally reviewed the curriculums and the course syllabi. Results : Forty-eight courses of 42 BSN programs were analyzed. Only five programs offered both theoretical and practical courses in critical care nursing; 22 offered theoretical courses and 26 offered practical courses. Most courses were offered as electives with 1 or 2 credits, and were taught by faculty who were experts in adult health nursing. Conclusion : The results show that there is a quantitative shortage of critical care nursing education in the curriculum of BSN programs in Korea. The lack of knowledge and skills on critical care can lead to a burden of new intensive care unit nurses and is a threat to patients' health. It is necessary to develop a practical and integrative curriculum for critical care nursing education.

• International Commerce and Information Review
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• v.11 no.4
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• pp.153-182
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• 2009

This paper intends to increase the performance of export support programs for small-to-medium sized firms promoted by Korea government. A research construct is suggested for effective government support program targeted on the global marketing capability. The data is collected from the firms received the support more than once by Korean governments. The results are shown as follows. First, it is found that those firms who have high propensity to be involved in export business have shown high performance. Second, the firms with high global marketing capability have shown good performance. To be more specific, organizational commitment, strategic initiative, business differentiation, and market knowledge for target markets are found to be critical factors in successful export support program. The business differentiation strategy in target market is very critical. Finally, the degree of program management effectiveness is found to be important in high performance firms. It means that for those firms, much more advanced programs need to be developed. The government should develop diversified programs by considering the degree of global marketing capability.

• KIPS Transactions on Software and Data Engineering
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• v.4 no.1
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• pp.1-8
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• 2015

Safety critical systems require exhaustive verification of safety properties, because even a single corner-case fault can cause a critical safety failure. However, existing verification approaches are too costly in terms of time and computational resource required, making it hard to be applied in practice. In this paper, we implemented a tool for minimizing the size of the verification target w.r.t. verification properties to check, based on program slicing technique[1]. The efficacy of program slicing using our tool is demonstrated in a case study with a verification target Trampoline[3], which is an open source automotive operating system compliant with OSEK/VDX[2]. Experiments have shown enhanced performance in verification, with a 71% reduction in the size of the code.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2001.07a
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• pp.901-904
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• 2001

For the c-axis oriented epitaxial YBa$_2$Cu$_3$O$_{7-{\delta}}$ thin film on r-cut sapphire substrate it is necessary to deposit buffer layers. The CeO$_2$buffer layer was deposited on sapphire substrate using RF magnetron sputtering system. We investigated XRD pattern of CeO$_2$thin films at various sputtering conditions such as sputtering gas ratio, sputtering power, target to substrate distance, sputtering pressure and substrate temperature. The optimum condition was 15 mTorr with deposition pressure, 1:1.2 with $O_2$and Ar ratio and 9cm with target to substrate distance. The CeO$_2$(200) peak was notable for a deposition temperature above 75$0^{\circ}C$. The YBa$_2$Cu$_3$O$_{7-{\delta}}$ was deposited on CeO$_2$buffered r-cut sapphire substrate using pulsed laser ablation. The YBa$_2$Cu$_3$O$_{7-{\delta}}$CeO$_2$(200)/A1$_2$O$_3$thin film was exhibited a critical temperature of 89K.xhibited a critical temperature of 89K.

• Journal of the Korean Institute of Landscape Architecture
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• v.34 no.5 s.118
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• pp.59-69
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• 2006

Nature-learning place is a critical space together with nature center in Natural parks. But there are serious faults on these design and planning as for the landscape ecological consideration. The objective of this paper was to suggest the ecological alternatives through analyzing existing cases of nature-teaming place in Natural parte. Five case sites in Natural parks were selected in Chollabukdo. Three landscape indices- subjectivity, natural prototype, nativity, were introduced for evaluating the existing cases. Results showed that those are short of landscape ecological senses- Biotope target species, ecological vegetation patches, eco-corridor concept. A proposal for the ecological planning in Deokyusan Natural park was suggested according to several criteria with biotopes as forest and stream patches and the corridor. The results of the study can be summarized as follows. First, existing natural-loaming sites should be evaluated in light of landscape ecological indices. Second, they can be designed to work with the concept of the biotope patch and corridor for target species. The results of this study could provide critical guidelines for the ecological planning and design of natural-loaming sites in nature parks.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.41 no.6
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• pp.99-108
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• 2004

In this paper, a new fast detection and clutter rejection method is proposed for CCD-image-based Automatic Target Detection System. For defence application, fast computation is a critical point, thus we concentrated on the ability to detect various targets with simple computation. In training stage, 1D template set is generated by regional vertical projection and K-means clustering, and binary tree structure is adopted to reduce the number of template matching in test stage. We also use adaptive skip-width by Correlation-based Adaptive Predictive Search(CAPS) to further improve the detecting speed. In clutter rejection stage, we obtain Fourier Descriptor coefficients from boundary information, which are useful to rejected clutters.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.551-560
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• 2014

Colorectal cancer (CRC) is the third most common malignancy and fourth most common cause of cancer mortality worldwide. Untreated chronic inflammation in the intestine ranks among the top three high-risk conditions for colitis-associated colorectal cancer (CAC). Signal Transducer and Activator of Transcription 3 (STAT3) protein is a member of the STAT family of transcription factors often deregulated in CRC. In this review, we try to emphasize the critical role of STAT3 in CAC as well as the crosstalk of STAT3 with inflammatory cytokines, nuclear factor (NF)-${\kappa}B$, PI3K/Akt, Mammalian Target of Rapamycin (mTOR), Notch, $Wnt/{\beta}$-catenin and microRNA (MiR) pathways. STAT3 is considered as a primary drug target to treat CAC in humans and rodents. Also we updated the findings for inhibitors of STAT3 with regard to effects on tumorigenesis. This review will hopefully provide insights on the use of STAT3 as a therapeutic target in CAC.

• Molecules and Cells
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• v.37 no.9
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• pp.691-698
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• 2014

SCYL1-BP1 is thought to function in the p53 pathway through Mdm2 and hPirh2, and mutations in SCYL1-BP1 are associated with premature aging syndromes such as Geroderma Osteodysplasticum; however, these mechanisms are unclear. Here, we report significant alterations in miRNA expression levels when SCYL1-BP1 expression was inhibited by RNA interference in HEK293T cells. We functionally characterized the effects of potential kernel miRNA-target genes by miRNA-target network and protein-protein interaction network analysis. Importantly, we showed the diminished SCYL1-BP1 dramatically reduced the expression levels of EEA1, BMPR2 and BRCA2 in HEK293T cells. Thus, we infer that SCYL1-BP1 plays a critical function in HEK293T cell development and directly regulates miRNA-target genes, including, but not limited to, EEA1, BMPR2, and BRCA2, suggesting a new strategy for investigating the molecular mechanism of SCYL1-BP1.