• Bulletin of the Korean Chemical Society
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• v.33 no.3
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• pp.971-974
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• 2012

The facilitated diffusion effect on protein-DNA binding is studied. A rigorous theoretical approach is presented to deal with the coupling between one-dimensional and three-dimensional diffusive motions. For a simplified model, the present approach can provide numerically exact results, which are confirmed by the lattice-based Monte Carlo simulations.

• 한국정보디스플레이학회:학술대회논문집
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• 2004.08a
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• pp.873-876
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• 2004

New Oligothiophene derivatives having liquid crystalline property have been designed, synthesized and characterized. New oligothiophene derivatives were prepared by a palladium-catalyzed cross-coupling reaction via zinc-substituted thiophene. The structures of materials were characterized by various spectroscopies. The new obtained oligothiophene derivatives showed high thermal stability above 300 $^{\circ}C$ and exhibited several transition temperatures, evidence of mesophase. In field-effect transistors, a charge carrier mobility of 1.9 x $10^{-2}$ $cm^2$/Vs was observed.

• Bulletin of the Korean Chemical Society
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• v.23 no.2
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• pp.351-354
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• 2002

A number of bis-2-oxo amide triacylglycerol analogues, a recently reported potent human gastric lipase inhibitor and its new analogues, have been prepared starting from 1,3-dibromo-2-propanol utilizing acyl cyanophosphorane methodology as a key step in a convergent manner. The key coupling reaction has been accomplished at -$78^{\circ}C$ between 1,3-diamino-2-propanol derivative and the labile diketo nitriles, derived from acyl cyanotriphenylphosphoranes upon oxidizing with $O_3$, under mild condition in moderate yields.

• Bulletin of the Korean Chemical Society
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• v.23 no.5
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• pp.769-772
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• 2002

• Proceedings of the KIPE Conference
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• 2008.06a
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• pp.164-166
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• 2008

Ultrasonic welder joins with a horn and a booster for amplification of the mechanical displacement. This coupling generates other resonance points at a frequency range lower than the piezoelectric material's resonance frequency. Therefore, frequency variation range through PLL control was proposed in order to prevent reaction to these resonance points.

• Journal of the Korean Chemical Society
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• v.18 no.3
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• pp.210-214
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• 1974

Through the copper catalyzed coupling reaction a uracil dimer, 5,5'-diuracil was synthesized from 5-uracildiazonium salt. Several derivatives of above diuracil dimer were also synthesized. The structure of the dimer was determined from their spectral data.

• Bulletin of the Korean Chemical Society
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• v.31 no.8
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• pp.2143-2146
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• 2010

A selective synthetic method of the 2,5-biaryltriazolones has been developed via copper-catalyzed N-arylation reaction. Aryltriazolones, which were readily prepared from commercially available compounds, were N-arylated to 2,5-biaryltriazolones with high regioselectivity. This approach allows for access to a variety of 2,5-biaryl-1,2,4-trizol-3-ones in a simple and practical manner.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2003.11a
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• pp.118-118
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• 2003

The use of PPARν (peroxisome proliferator activated receptor ν) activators in the treatment of type 2 diabetes is well established due to their ability to lower blood glucose and insulin levels and omprove insulin sensitivity. Thiazolidinedione analog is one of the potential antidiabetic drug that binds and activates PPARν selectively. In an effort to develop novel and effective antidiabetic thiazolidindione analogs, synthesis of tetrahydroquinoline and para-substituted benzene-linked thiazolidinedione analogs were carried out via coupling reaction of the hydrophobic segments with hydroxybenzylthiazolidinedione.

• YAKHAK HOEJI
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• v.37 no.3
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• pp.243-246
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• 1993

Six N-substituted-5-hydroxyanthranilic acids were synthesized by the coupling reaction of 5-tosyloxyanthranilic acid ethyl ester with corresponding acid chlorides. The structure of the obtained compounds was proved by NMR and IR. These compounds did not inhibit the growth of micro-organisms while suppressed HSV-1 replication in vero cell at 100 $\mu\textrm{g}$/ml.

• YAKHAK HOEJI
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• v.45 no.6
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• pp.570-574
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• 2001

In order to discover new useful NSAIDs, novel N-substituted 1,2-benzisothiazoline-3-one 1,1- dioxide derivatives, which can exhibit potentially antiinflammatory activity were synthesized. 1,2-Benz-isothiazoline-3-one-N-acetic acids 6a, b were obtained from monochloroacetic acid and sodium 1,2-benz-isothiazoline-3-ones in DMF by N-alkylation reaction. N-Substituted 1,2-benzisothiazoline-3-one 1,1-dioxide derivatives 7a-e were synthesized through the coupling of compound 6a, b and several amines (aniline, 2- aminopyridine , 2-aminothiazole, 2-aminotetrazole) with dicyclohexylcarbodiimide in methyl e no chloride.