• KSBB Journal
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• 제19권4호
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• pp.257-262
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• 2004

최근, 미세조류에 대한 생물공학적 관심이 급격히 증가하고 있으며 이의 응용범위는 식품이나 제약, 화장품 등 다양한 구도로 확장되어지고 있다. 고농도의 미세조류 배양을 위해서는 빛이 핵심적 제한요소로 작용되어지며 빛의 투과 깊이나 강도에 따라 균체의 성장속도가 결정되어지게 된다. 본 연구에서는 다양한 빛의 투과경로와 빛을 받는 면적/배양액의 부피 비율, 조도 그리고 단계적 조사에 따른 Chlorella sp.의 성장률을 조사하여 빛이 미세조류에 미치는 영향을 알아보았으며, 본 연구에 적용된 값들 중 4 cm의 직경, 57.6%의 면적/부피 비율, 62 $\mu$mo1/$m^2$/s의 조도에서 Chlorella sp. 성장에 필요한 빛 에너지를 가장 효율적으로 이용함을 확인할 수 있었다.

• 한국정밀공학회지
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• 제30권5호
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• pp.544-551
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• 2013

Recently high speed mixer, which is mixing, grinding, dispersion for liquid-liquid material, has been widely used several industries such as food, cosmetics, pharmaceuticals, fine chemicals, electronic material. This high speed mixer has a core element part called particle separation device. Particle separation device, which makes mixed liquid and liquid material using shear forces from a rotor and a stator, is a decisive factor in the distributed parts. In this study, we examined the velocity distribution of the two models of particle separation device using computation fluid dynamics, so that we were able to see the difference of the velocity distribution according to the shape. Also, by experiment, we observed that the use of rotor-screen type is deemed more suitable in case of accurately considering the effect of improving of the dispersibility through the circulation of the future.

• 한국의상디자인학회지
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• 제7권2호
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• pp.87-99
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• 2005

This study is to examine the modern women's awareness make-up in psychological standpoint based upon the survey of $20\~30$ years old women's consciousness of the motivation, the attention, the psychological utility, the attitude for make-up, the action behavior and the coordination with clothes. Modern women show a keen interest in make-up in company with the diversity of a fashion. This means the tendency which the intention for change and the expression of oneself are emphasizing on. The motivations of make-up are women's attention to other people and notice of evaluation of others and social meaning of make-up in relation with one's interest in appearances. Also, total coordination is concerned as another motivation. Make-up became the practical use and usual doings for women with the diversity of the information of make-up & the increase of cosmetics. Since there were so many women responded that they start to make up in their teens, we recognized that the women's sense of values has changed with the change of modern society.

• 대한화장품학회지
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• 제35권3호
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• pp.171-177
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• 2009

본 총설에서는 세라마이드를 함유한 다양한 조성의 안정한 라멜라 구조체 제조 및 그들의 분산에 대한 기술을 소개하였다. DSC, x-ray diffraction 및 FT-IR spectra를 이용하여 라멜라 구조체의 성질을 평가했으며, 세라마이드와 함께 적절한 오일, 계면활성제, 또는 지질로 구성된 형태의 안정한 라멜라 구조체 형성을 자세히 설명하였다. 세라마이드를 이용 하기 위한 다양한 접근 방법은 에멀전 및 리포좀 제조에 이용 될 것이며 나아가 화장품, 의약품 및 약물 전달분야에 응용 할 수 있을 것이다.

• 동의생리병리학회지
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• 제31권6호
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• pp.380-384
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• 2017

From March 1, 2017 to May 31, 2017, subjects were allowed to apply a wrinkle-improving herbal cosmetic product containing the extract of Douchi for 8 weeks. The effectiveness of herbal cosmetics was evaluated through wrinkle improvement efficacy parameter analysis, subjective wrinkle improvement through questionnaires, and adverse reaction. The herbal cosmetic products containing the extract of Douchi showed a significant decrease in the wrinkle improvement efficacy parameter analysis result. The results of the subjective satisfaction analysis after use were also evaluated positively. We could confirm the possibility of wrinkle improvement effect of Douchi extract, and it will be possible to contribute to the expansion of korean medicine field through more studies in the future.

• Biotechnology and Bioprocess Engineering:BBE
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• 제5권4호
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• pp.263-274
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• 2000

Carotenoids are widely distributed natural pigments which are in an increasing demand by the market, due to their applicatins in the human food, animal feed, cosmetics, and pharmaceutical industries. Although more than 600 carotenoids have been identified in nature, only a few are industrially important (${\beta}$-carotene, astaxanthin, lutein or lycopene). To date chemical processes manufacture most of the carotenoid production, but the interest for carotenoids of biological origin is growing since theire is an increased public concern over the safety of artificial food colorants. Although much interest and effort has been devoted to the use of biological sources for industrially important carotenoids, only the production of biological ${\beta}$-carotene and astaxanthin has been reported. Among fungi, several Mucorales strains, particularly Blakeslea trispora, have been used to develop fermentation processes for the production of ${\beta}$-carotene on almost competitive cost-price levels. Similarly, the basidiomycetous yeast Xanthophyllomyces dendrorhous (the perfect state of Phaffia rhodozyma), has been proposed as a promising source of astaxanthin. This paper focuses on recent findings on the fungal pathways for carotenoid production, especially the structure and function of the genes involved in the biosynthesis of carotenoids in the Mucorales. An outlook of the possibilities of an increased industrial production of carotenoids, based on metabolic engineering of fungi for carotenoid content and composition, is also discussed.

• 한국의류산업학회지
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• 제16권2호
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• pp.312-318
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• 2014

This study examined the correlation between a handle evaluation of cosmetic puff textile and a sensory evaluation. The KES-F system was used to analyze the main mechanical factors for the handle evaluation and a statistical method was used for the sensory evaluation. The results revealed different mechanical properties and handle values of the tested cosmetic puff textiles. A material type and structure of the cosmetic textile affected the handle property of the material which is the most important factor for a cosmetic purpose. Particularly, the physical properties of textile material are likely to be important factors for the sensory property of cosmetic material. In addition, the sensory evaluation also revealed different sensory characteristics of the cosmetic efficiency according to the cosmetic puff textile. No close relationship was observed between the mechanical properties and sensory evaluation on the cosmetic puff textiles. The sensory evaluation of a cosmetic efficiency is not only decided by the physical and mechanical characteristics of the cosmetic textile material. Overall, when using textiles used for the cosmetic purposes, it is important to consider not only the proper mechanical properties of the textiles but also the use and sensory satisfaction. Development and selection of the cosmetic textiles should be focused on both the material function and consumer satisfaction.

• 한국응용과학기술학회지
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• 제14권2호
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• pp.93-102
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• 1997

Isothiazoline derivatives is widely used to food, medical drug and industrial goods, cosmetics etcs, and it makes to restrain and to sterilize a breeding of microbe as a preservative and a sterilizing agent. It differs with the raw material of paraoxybenzoic acid derivatives or imidazolydinyl urea to be in use at present, on the efficacy and effect, and has various characteristics. This synthesis makes 3,3'-dithiodipropionic chloride to add a thionyl chloride in 3,3'-dithiodipropionic acid, and 3,3'-dithiodipropionic methyl amide makes to synthesize in a reflux reaction the mono methyl amine to 3,3'-dithiodipropionic chloride. And last synthesis becomes to make chlorination-cyclization molecule doing a reflux reaction in the temperature of $90{\sim}100^{\circ}C$ to mix excessively thionyl chloride and ethylene dichloride to 3,3'-dithiodipropionic methyl amide. The last synthesis material has got in the mixture of 5-chloro-2-methyl-4-isothiazoline-3-one and 2-methyl-4-isothiazoline-3-one, and it is so-called isothiazoline derivatives. The purification of isothiazoline derivatives makes to fuse in ethyl acetate, and makes to decolorize and to deodorize in recrystallization. This experiment has been in synthesis and purification of isothiazoline derivatives, and has tried to measure on the antisepsis and sterilization function of microbe according to pH or content change.

• Toxicological Research
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• 제33권3호
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• pp.191-203
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• 2017

Human eyes and skin are frequently exposed to chemicals accidentally or on purpose due to their external location. Therefore, chemicals are required to undergo the evaluation of the ocular and dermal irritancy for their safe handling and use before release into the market. Draize rabbit eye and skin irritation test developed in 1944, has been a gold standard test which was enlisted as OECD TG 404 and OECD TG 405 but it has been criticized with respect to animal welfare due to invasive and cruel procedure. To replace it, diverse alternatives have been developed: (i) For Draize eye irritation test, organotypic assay, in vitro cytotoxicity-based method, in chemico tests, in silico prediction model, and 3D reconstructed human cornealike epithelium (RhCE); (ii) For Draize skin irritation test, in vitro cytotoxicity-based cell model, and 3D reconstructed human epidermis models (RhE). Of these, RhCE and RhE models are getting spotlight as a promising alternative with a wide applicability domain covering cosmetics and personal care products. In this review, we overviewed the current alternatives to Draize test with a focus on 3D human epithelium models to provide an insight into advancing and widening their utility.

• Bulletin of the Korean Chemical Society
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• 제28권8호
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• pp.1396-1400
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• 2007

In this study, poly(iso-butyl methacrylate-co-ethylene glycol dimethacrylate) [poly(iso-BMA-co-EGDMA)] microgel was prepared and used as a face powder additive. The spreading, adhesiveness, and skin reactivity of poly(iso-BMA-co-EGDMA) microgel-containing face powder II were investigated and compared with the same properties of commercially available Silica bead 700-containing face powder I. In the results, the particle size of the poly(iso-BMA-co-EGDMA) microgel was significantly swelled as a result of sebum absorption. Face powder II showed a lower primary irritation index and a higher adhesiveness than did face powder I. Face powder I showed a low sebum absorption ratio and a relatively high rate of sebum absorption, whereas face powder II, contrastingly, exhibited a high sebum absorption ratio and a low rate of sebum absorption, which properties would reduce the phenomena of facial strain and sliminess. These results indicate that poly(iso- BMA-co-EGDMA) microgel has outstanding sebum absorption characteristic and adhesiveness, and thus that it is a good candidate for use as a face powder additive.