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Formation and Dispersion of Stable Lamellar Structure Containing Ceramide  

Kim, Do-Hoon (Amore-Pacific Co. R&D Center)
Oh, Seong-Geun (Department of Chemical Engineering, Hanyang University)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.35, no.3, 2009 , pp. 171-177 More about this Journal
Abstract
This study described formation and dispersion of stable lamellar structure containing ceramide. To characterize of the lamellar structure containing ceramide, we used differential scanning calorimetry, x-ray diffraction, and FT-IR spectra, which enabled us to demonstrate that ceramide with appropriate amounts of lipid, oil and surfactant can assemble to form a stable lamellar-phase. These approaches to use ceramide offers useful means to fabricate a variety of biocompatible emulsion and liposome, which enlarge their applicability in the fields of drug delivery, dermatology and cosmetics.
Keywords
ceramide; lipid; drug delivery; cosmetic; lamellar;
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1 P. M. Elias, Epidermal lipids, barrier function and desquamation, J. Invest. Dermatol., 80, 44 (1983)   DOI   ScienceOn
2 P. M. Wertz and D. T. Dowing, Glycolipids in mammalian epidermis: structure and function in the water barrier, Science, 217, 1261 (1982)   DOI   PUBMED   ScienceOn
3 P. M. Elias, Epidermal lipids, membranes and keratinization, Int. J. Dermatol., 20, 1 (1981)   DOI   PUBMED
4 D. T. Downing, M. E. Stewart, P. W. Wertz, S. W. Colton VI, W. Abraham, and J. S. Strauss, Skin lipids: an update, J. Invest. Dermatol., 88, 29 (1987)
5 G. Imokawa, S. Akasaki, H. Hattori, and N. Yoshizuka, Selective recovery of deranged waterholding properties by stratum corneum lipids, J. Invest. Dermatol., 87, 758 (1986)   DOI   ScienceOn
6 A. Sekiguchi, J. Manosroi, A. Manosroi, H. Yamauchi, and M. Abe, Molecular interactions between phospholipids and glycolipids in a lipid bilayer, Colloid Surf. B, 4, 287 (1995)   DOI   ScienceOn
7 S. L. Chamlin, J. Kao, I. J. Frieden, M. Y. Sheu, A. J. Fowler, and J. W. Fluhr, Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity, J. Am. Acad. Dermatol., 47, 198 (2002)   DOI   ScienceOn
8 D. H. Kim, S. G. Oh, Y. J. Lee, Y. J. Kim, H. K. Kim, and H. H. Kang, Emulsion properties of pseudo- ceramide PC104/water/polyoxyethylene cholesteryl ether and polyoxyethylene cetyl ether mixtures, Colloid Surf. A, 207, 177 (2002)   ScienceOn
9 H. Iwai, J. Fukasawa, and T. Suzuki, Thermotropic behavior of stratum corneum lipids containing a pseudo-ceramide, Int. J. Cosmet. Sci., 20, 87 (1998)   DOI   ScienceOn
10 G. M. Golden, D. B. Guzek, A. H. Kennedy, J. E. Mckie, and R. O. Potts, Stratum corneum lipid phase transitions and water barrier properties, Biochemistry, 26, 2382 (1987)   DOI   ScienceOn
11 H. D. Onken and C. A. Moyer, The water barrier in human epidermis, Arch. Dermatol., 87, 584 (1963)   DOI   PUBMED   ScienceOn
12 P. M. Elias, Lipids and the epidermal permeability barrier, Arch. Dermatol., 270, 95 (1981)   DOI   PUBMED   ScienceOn
13 P. A. Bowser and R. J. White, Isolation, barrier properties and lipid analysis of stratum compactum, a discrete region of the stratum corneum, Br. J. Dermatol., 112, 1 (1985)   DOI   ScienceOn
14 M. W. Jeong, S. G. Oh, D. H. Kim, J. S. Ko, and S. W. Oh, Phase diagram and emulsion properties of n-octyl-D-glucoside/water/octanoic acid containing pseudo-ceramide mixtures, Colloid Surf. A, 193, 197 (2001)   DOI   ScienceOn
15 P. W. Wertz, W. Abraham, L. Landman, and D. T. Downing, Preparation of liposomes from stratum corneum lipids, J. Invest. Dermatol., 87, 582 (1986)   DOI   ScienceOn
16 G. Grubauer, K. R. Freingold, R. M. Harris, and P. M. Elias, Lipid content and lipid type as determinants of the epidermal permeability barrier, J. Lipid Res., 30, 89 (1989)   PUBMED   ScienceOn
17 P. W. Wertz, D. C. Swartzendruber, K. C. Madison, and D. T. Downing, The composition and morphology of epidermal cyst lipids, J. Invest. Dermatol., 89, 419 (1987)   DOI   ScienceOn
18 M. A. Lampe, A. L. Burlingame, J. Whitney, M. I. Williams, B. E. Brow, E. Roitman, and P. M. Elias, Human stratum corneum lipids: characterization and regional variations, J. Lipid Res., 24, 120 (1983)   PUBMED   ScienceOn
19 W. Abraham and D. T. Downing, Lamellar structures formed by stratum corneum lipids in vitro: a deuterium nuclear magnetic resonance (NMR) study, Pharm. Res., 9, 1415 (1992)   DOI   ScienceOn
20 D. H. Kim, E. J. An, J. W. Kim, S. H. Han, J. W. Kim, S. G. Oh, K. D. Suh, and E. C. Cho, Fabrication and characterization of pseudo-ceramide-based liposomal membranes, Colloid Surf. B, 73, 207 (2009)   DOI   ScienceOn
21 W. Abraham and D. T. Downing, Deuterium NMR investigation of polymorphism in stratum corneum lipids, Biochim. Biophys. Acta., 1068, 189 (1991)   DOI   ScienceOn