• 제목/요약/키워드: correction formula

검색결과 140건 처리시간 0.023초

$^{86}Rb$을 이용한 국소 혈류량 측정편법 (A Simplified Method for the Local Blood Flow Determination in Rats and Rabbits by means of $^{86}Rb$)

  • 성호경;고주환;문광남;이장규
    • 대한핵의학회지
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    • 제5권2호
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    • pp.65-71
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    • 1971
  • A simplified method for the local blood flow determination by means of $^{86}Rb$ was developed in rats and rabbits. $^{86}Rb$ in the form of chloride mixed with physiological saline was intravenously injected. The doses were $10{\mu}Ci$ for rats and $100{\mu}Ci$ for rabbits, which were injected in less than 5 seconds. The rats were sacrificed after 30 seconds, and the rabbits at the intervals of 10, 20, 40 and 60 seconds, by decapitation or rapid intravenous injection of 3 to 5ml of saturated KCI. After bleeding, the organ and tissue samples, e.g. lungs, renal cortex, jejunum and skeletal muscle were quickly removed. The $^{86}Rb$ uptake in 1 gram of the organs and tissues were measured. On the basis of uptake value, administered dose and body weight, the local blood flow was calculated. Following were the results: 1. The uptake values of $^{86}Rb$ in the above organs and tissues of rats were different from other previous reports, in which the large rats were used. It appears, therefore, that the correction on the basis of body weight is necessary. 2. The uptakes of $^{86}Rb$ in the above organs and tissues of rabbits remained rather stationary within 20 to 40 seconds. 3. The local blood flow in the above organs and tissues were calculated from $^{86}Rb$ uptake in per cent dose per 1 gram tissue for 200 gram body weight. The formula could be applied not only to the rabbits but to the rats. 4. The present method could be applied to the comparison of the local blood flow between the various organs and tissues of the control and experimental animals.

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Occupational Burden of Cancer in Korea

  • Kim, Eun-A;Lee, Hye-Eun;Kang, Seong-Kyu
    • Safety and Health at Work
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    • 제1권1호
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    • pp.61-68
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    • 2010
  • Objectives: The extent of the occupational cancer burden has rarely been estimated in Korea. The aim of this study is to provide an estimation of the population attributable fraction (PAF) of occupational cancer in Korea. Methods: Nine kinds of Group 1 carcinogens addressed by the International Agency for Research on Cancer (IARC) and 7 kinds of cancer were selected for the target carcinogens and diseases, respectively. The prevalence of carcinogen-exposed workers was estimated and correction factors were applied so that the value would be representative of the total population. Data on relative risk (RR) were taken from IARC reports and were compared with the RRs from the studies on Korean workers. The PAF was estimated according to Levin's formula. Results: The proportion of the general Korean population exposed to carcinogens was 9.7%. The PAF of total cancer was 1.1% for incident cancer cases and 1.7% for cancer deaths. The PAFs of lung cancer and leukemia were 7.0% and 4.5%, respectively. With the RRs reported from Korean studies, the PAF for lung cancer and leukemia were 3.7% and 3.4%, respectively. Conclusion: The PAF in this study (1.1%) was lower than that reported in previous studies (2-4%) from developed countries. Considering that only 9 of the 29 kinds of Group 1 carcinogens were included in this study, the PAF might be underestimated. However, because the process of industrialization in Korea differs from that which occurred in other developed countries, 1.1% of the PAF might be appropriate for Korea.

Evaluating the accuracy (trueness and precision) of interim crowns manufactured using digital light processing according to post-curing time: An in vitro study

  • Lee, Beom-Il;You, Seung-Gyu;You, Seung-Min;Kim, Dong-Yeon;Kim, Ji-Hwan
    • The Journal of Advanced Prosthodontics
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    • 제13권2호
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    • pp.89-99
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    • 2021
  • PURPOSE. This study aimed to compare the accuracy (trueness and precision) of interim crowns fabricated using DLP (digital light processing) according to post-curing time. MATERIALS AND METHODS. A virtual stone study die of the upper right first molar was created using a dental laboratory scanner. After designing interim crowns on the virtual study die and saving them as Standard Triangulated Language files, 30 interim crowns were fabricated using a DLP-type 3D printer. Additively manufactured interim crowns were post-cured using three different time conditions-10-minute post-curing interim crown (10-MPCI), 20-minute post-curing interim crown (20-MPCI), and 30-minute post-curing interim crown (30-MPCI) (n = 10 per group). The scan data of the external and intaglio surfaces were overlapped with reference crown data, and trueness was measured using the best-fit alignment method. In the external and intaglio surface groups (n = 45 per group), precision was measured using a combination formula exclusive to scan data (10C2). Significant differences in accuracy (trueness and precision) data were analyzed using the Kruskal-Wallis H test, and post hoc analysis was performed using the Mann-Whitney U test with Bonferroni correction (α=.05). RESULTS. In the 10-MPCI, 20-MPCI, and 30-MPCI groups, there was a statistically significant difference in the accuracy of the external and intaglio surfaces (P<.05). On the external and intaglio surfaces, the root mean square (RMS) values of trueness and precision were the lowest in the 10-MPCI group. CONCLUSION. Interim crowns with 10-minute post-curing showed high accuracy.

Most Reliable Time in Predicting Residual Kyphosis and Stability: Pediatric Spinal Tuberculosis

  • Moon, Myung-Sang;Kim, Sang-Jae;Kim, Min-Su;Kim, Dong-Suk
    • Asian Spine Journal
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    • 제12권6호
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    • pp.1069-1077
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    • 2018
  • Study Design: A case study. Purpose: To assess the chronological changes of the disease-related kyphosis after chemotherapy alone, secondly to clarify the role of growth cartilage in the healed lesion on kyphosis change, and to define the accurate prediction time in assessing residual kyphosis. Overview of Literature: None of the previous papers up to now dealt with the residual kyphosis, stability and remodeling processes of the affected segments. Methods: One hundred and one spinal tuberculosis children with various stages of disease processes, age 2 to 15 years, were the subject materials, between 1971 to 2010. They were treated with two different chemotherapy formula: before 1975, 18 months of triple chemotherapy (isoniazid [INH], para-aminosalicylic acid, streptomycin); and since 1976, 12 months triple chemotherapy (INH, rifampicin, ethambutol, or pyrazinamide). The first assessment at post-chemotherapy one year and at the final discharge time from the follow-up (36 months at minimum and 20 years at maximum) were analyzed by utilizing the images effect of the remaining growth plate cartilage on chronological changes of kyphosis after initiation of chemotherapy. Results: Complete disc destruction at the initial examination were observed in two (5.0%) out of 40 cervical spine, eight (26.7%) out of 30 dorsal spine, and six (19.4%) out of 31 lumbosacral spine. In all those cases residual kyphosis developed inevitably. In the remainders the discs were partially preserved or remained intact. Among 101 children kyphosis was maintained without change in 20 (19.8%), while kyphosis decreased in 14 children (13.7%), and increased in 67 children (66.3%) with non-recoverably damaged growth plate, respectively. Conclusions: It could tentatively be possible to predict the deformity progress or non-progress and spontaneous correction at the time of initial treatment, but it predictive accuracy was low. Therefore, assessment of the trend of kyphotic change is recommended at the end of chemotherapy. In children with progressive curve change, the deformity assessment should be continued till the maturity.

해양 및 내륙 정밀 PNT 사용자 성능 최적화를 위한 내륙 기준국 배치 연구 (A Study on Deployment of Inland Reference Stations for Optimizing Marine and Inland User Performance Using Precise PNT)

  • 이예빈;박병운
    • 한국항행학회논문지
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    • 제27권4호
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    • pp.396-409
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    • 2023
  • 위성항법시스템은 사용자에게 위치 및 시각정보를 제공하기 위한 핵심 기술로, 최근 자율 이동체 분야에서 요구되는 높은 정확도 및 신뢰성을 확보하기 위하여 다양한 형태의 위성항법보강시스템이 개발되고 있다. 위성항법보강시스템은 사용자 측위 성능 개선을 위해 지상 기준국에서 수집된 거리 측정치 및 항법 데이터를 기반으로 보강정보를 생성한다. 기준국의 배치 및 간격이 시스템 성능에 중요한 영향을 미치므로, 위성항법보강시스템 구축 시 기준국 설치 지점에 대한 고려가 필요하다. 본 논문에서는 기준국의 배치 및 간격에 따른 사용자 측위 성능 모델링 식을 활용한 신규 기준국설치 지점 도출 방안을 분석하고 시뮬레이션을 통해 사용자 측위 성능을 최적화할 수 있는 후보군 지역을 선정하여 제안하였다.

연소물의 질량증가와 연소시간의 상관관계를 고려한 화재곡선 예측 (Prediction of Fire Curves Considering the Relationship between Mass Increase and Combustion Time of Combustibles)

  • 남은준;이태일;지광습
    • 한국구조물진단유지관리공학회 논문집
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    • 제28권2호
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    • pp.9-16
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    • 2024
  • 본 논문에서는 부피단위의 화재곡선을 단위면적당 화재곡선으로 구하여 화재곡선 식을 FDS 표면열방출율법에 대입할 수 있도록 하고자 하였다. 화재곡선을 총 연소특성시간을 고려하여 무차원으로 표현하였으며, 성장구간비 𝛽i, 유지구간비 𝛽s , 감쇄구간비 𝛽d를 고려하여 화재강도에 대한 적절한 비율을 나타내도록 개선하였다. 또한, 질량증가에 따라 변화하는 연소 특성시간 보정함수 𝛾(m/m0)를 도출하였으며, 질량비가 증가함에 따라 성장시간 값을 제어하기 위해 성장구간비 𝛽i를 보정하는 함수 αi(m/m0)를 도출하였다. 이에 따라 기존 데이터를 활용하여 연소물의 기준질량을 선정하고, 질량 증가에 따른 화재곡선을 예측할 수 있는 식을 확립하였다.

유방암 환자의 삼문 조사 시 내외측 접면 조사야의 Posterior Edge의 어긋남의 교정 (Correction Method on Mismatched Posterior Edge of Medial and Lateral Tangential Fields for Three Fields Techniques in Breast Cancer)

  • 김헌정;노준규;김우철;박성용
    • Radiation Oncology Journal
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    • 제21권2호
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    • pp.174-181
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    • 2003
  • 목적: 유방암 환자를 삼문으로 방사선치료할 경우 유방의 접면 영역과 쇄골상 영역의 기하학적 일치를 이루기 위해 갠트리를 회전한 상태에서 테이블을 회전하는 방법이 사용되며, 이때 접면 조사의 posterior edge에 발생할 수 있는 어긋남을 필름선량측정법과 삼차원입체조영치료계획을 통하여 확인하고, 그 어긋남의 해결방법으로 콜리메이터의 각도를 보정해주는 방법들을 연구하였다. 대상 및 방법: 어긋남의 보정을 위해 쇄골상 영역과 유방의 접면 영역을 반쪽 빔 블록과 tangential field block을 사용하여 모의치료한 후 테이블 회전을 하지 않은 상태에서 환자의 몸에 접면 빔의 posterior edge에 선을 긋고, 테이블을 회전시킨 상태에서의 광조사야의 posterior edge와 테이블 회전 이전에 환자의 몸에 그어 놓은 선과 일치되도록 콜리메이터를 회전시키는 방법과, 본 연구에서 고안한 방법인 삼각함수로부터 유도시킨 다음과 같은 공식에 따라 콜리메이터를 회전하여 posterior edge의 어긋남을 보정하고 두 방법을 비교하였다. Co=$2sin^{-1}${$sin\{theta}\{cdot}sin(C/2)$} (Co: collimator angle, $\theta$: angle between tangential beam and table, C: couch angle) 결과: 필름선량측정법을 이용하여 콜리메이터를 보정하지 않은 경우 내외측의 접면 빔의 posterior edge가 어긋남을 확인할 수 있었으며, 콜리메이터를 보정함으로써 posterior edge의 일치함을 확인할 수 있었다. 위 두 방법에서 콜리메이터의 회전 각도는 동일하였다. 또한 전산화된 삼차원입체조영치료계획을 통하여, 접면 빔의 posterior edge의 어긋남을 확인할 수 있었으며, 콜리메이터를 회전하여 보정 함으로써 posterior edge의 일치를 확인할 수 있었다. 각각의 선량체적표를 비교할 경우, 콜리메이터를 보정하여 posterior edge의 일치를 이룬 경우가 더 적은 용적의 폐가 조사되는 것을 확인할 수 있었다. 결론: 유방암 환자의 방사선 치료에서 삼문으로 치료할 경우에 갠트리와 테이블을 동시에 회전하여 쇄골위 영역의 아래 면과 접면 빔의 윗면을 일치시킬 때 각각의 접면 빔의 posterior edge가 어긋남을 인지해야 하며, 약간의 콜리메이터를 회전시킴으로써 이 어긋남은 보정가능하고, 폐에 조사되는 방사선 양도 줄일 수 있었다.

토양수분함량 예측 및 계획관개 모의 모형 개발에 관한 연구(I) (A Study on the Development of a Simulation Model for Predicting Soil Moisture Content and Scheduling Irrigation)

  • 김철회;고재군
    • 한국농공학회지
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    • 제19권1호
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    • pp.4279-4295
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    • 1977
  • Two types of model were established in order to product the soil moisture content by which information on irrigation could be obtained. Model-I was to represent the soil moisture depletion and was established based on the concept of water balance in a given soil profile. Model-II was a mathematical model derived from the analysis of soil moisture variation curves which were drawn from the observed data. In establishing the Model-I, the method and procedure to estimate parameters for the determination of the variables such as evapotranspirations, effective rainfalls, and drainage amounts were discussed. Empirical equations representing soil moisture variation curves were derived from the observed data as the Model-II. The procedure for forecasting timing and amounts of irrigation under the given soil moisture content was discussed. The established models were checked by comparing the observed data with those predicted by the model. Obtained results are summarized as follows: 1. As a water balance model of a given soil profile, the soil moisture depletion D, could be represented as the equation(2). 2. Among the various empirical formulae for potential evapotranspiration (Etp), Penman's formula was best fit to the data observed with the evaporation pans and tanks in Suweon area. High degree of positive correlation between Penman's predicted data and observed data with a large evaporation pan was confirmed. and the regression enquation was Y=0.7436X+17.2918, where Y represents evaporation rate from large evaporation pan, in mm/10days, and X represents potential evapotranspiration rate estimated by use of Penman's formula. 3. Evapotranspiration, Et, could be estimated from the potential evapotranspiration, Etp, by introducing the consumptive use coefficient, Kc, which was repre sensed by the following relationship: Kc=Kco$.$Ka+Ks‥‥‥(Eq. 6) where Kco : crop coefficient Ka : coefficient depending on the soil moisture content Ks : correction coefficient a. Crop coefficient. Kco. Crop coefficients of barley, bean, and wheat for each growth stage were found to be dependent on the crop. b. Coefficient depending on the soil moisture content, Ka. The values of Ka for clay loam, sandy loam, and loamy sand revealed a similar tendency to those of Pierce type. c. Correction coefficent, Ks. Following relationships were established to estimate Ks values: Ks=Kc-Kco$.$Ka, where Ks=0 if Kc,=Kco$.$K0$\geq$1.0, otherwise Ks=1-Kco$.$Ka 4. Effective rainfall, Re, was estimated by using following relationships : Re=D, if R-D$\geq$0, otherwise, Re=R 5. The difference between rainfall, R, and the soil moisture depletion D, was taken as drainage amount, Wd. {{{{D= SUM from { {i }=1} to n (Et-Re-I+Wd)}}}} if Wd=0, otherwise, {{{{D= SUM from { {i }=tf} to n (Et-Re-I+Wd)}}}} where tf=2∼3 days. 6. The curves and their corresponding empirical equations for the variation of soil moisture depending on the soil types, soil depths are shown on Fig. 8 (a,b.c,d). The general mathematical model on soil moisture variation depending on seasons, weather, and soil types were as follow: {{{{SMC= SUM ( { C}_{i }Exp( { - lambda }_{i } { t}_{i } )+ { Re}_{i } - { Excess}_{i } )}}}} where SMC : soil moisture content C : constant depending on an initial soil moisture content $\lambda$ : constant depending on season t : time Re : effective rainfall Excess : drainage and excess soil moisture other than drainage. The values of $\lambda$ are shown on Table 1. 7. The timing and amount of irrigation could be predicted by the equation (9-a) and (9-b,c), respectively. 8. Under the given conditions, the model for scheduling irrigation was completed. Fig. 9 show computer flow charts of the model. a. To estimate a potential evapotranspiration, Penman's equation was used if a complete observed meteorological data were available, and Jensen-Haise's equation was used if a forecasted meteorological data were available, However none of the observed or forecasted data were available, the equation (15) was used. b. As an input time data, a crop carlender was used, which was made based on the time when the growth stage of the crop shows it's maximum effective leaf coverage. 9. For the purpose of validation of the models, observed data of soil moiture content under various conditions from May, 1975 to July, 1975 were compared to the data predicted by Model-I and Model-II. Model-I shows the relative error of 4.6 to 14.3 percent which is an acceptable range of error in view of engineering purpose. Model-II shows 3 to 16.7 percent of relative error which is a little larger than the one from the Model-I. 10. Comparing two models, the followings are concluded: Model-I established on the theoretical background can predict with a satisfiable reliability far practical use provided that forecasted meteorological data are available. On the other hand, Model-II was superior to Model-I in it's simplicity, but it needs long period and wide scope of observed data to predict acceptable soil moisture content. Further studies are needed on the Model-II to make it acceptable in practical use.

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Landsat TM과 ETM+를 이용한 인도네시아 메라피 화산의 화산쇄설물 분포와 지표 온도 시계열 분석 (Time-series Analysis of Pyroclastic Flow Deposit and Surface Temperature at Merapi Volcano in Indonesia Using Landsat TM and ETM+)

  • 조민지;종루;이창욱
    • 대한원격탐사학회지
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    • 제29권5호
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    • pp.443-459
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    • 2013
  • 자바 섭입대 위에 존재하는 인도네시아 메라피 화산은 1~5년의 주기를 가지는 화산활동이 활발한 성층화산이다. 대체적으로 화산폭발지수가 1-3정도의 규모로 나타나는데 비해 최근 2010년 분화는 화산폭발지수가 4까지 올라가 386명을 사망자를 유발했다. 본 연구에서는 40년간 지구를 관측해온 Landsat 영상을 이용하여 18년 동안 메라피 화산의 지표변화를 관측하였다. 연구를 위해 1994년 7월 6일부터 2012년 9월 1일까지 총 55장의 Landsat-5,7 영상을 수집하였으며, 밴드조합영상을 통해 화산쇄설류의 흐름이 시간에 따라 이동함을 확인하였다. 화산쇄설류가 덮고 있는 지역을 추출하기 위해서, COST model을 이용한 대기보정 후 감독분류를 수행하였으며, 그 결과 CVP 보고서에 기재된 화산쇄설류의 분화 방향과 추출된 화산쇄설류 영역의 변화가 거의 일치했다. NASA에서 제공하는 Landsat-5,7 위성의 열적외선 밴드를 이용한 온도 추출 기법을 적용하여 분화구 지역의 평균 지표온도를 산출한 결과, 분화 전 지표 온도가 급격히 상승하고, 분화 후 온도가 하강하는 양상을 반복적으로 나타냈다. 비록 기상조건에 따른 영상획득에 제약이 있지만, 장기간 발생된 메라피 화산의 지표변화를 확인하는데 있어서 Landsat 위성 영상이 매우 유용한 도구임을 확인했다.

Set-up errors in head and neck cancer treated with IMRT technique assessed by cone-beam computed tomography: a feasible protocol

  • Delishaj, Durim;Ursino, Stefano;Pasqualetti, Francesco;Matteucci, Fabrizio;Cristaudo, Agostino;Soatti, Carlo Pietro;Barcellini, Amelia;Paiar, Fabiola
    • Radiation Oncology Journal
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    • 제36권1호
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    • pp.54-62
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    • 2018
  • Purpose: To investigate set-up errors, suggest the adequate planning target volume (PTV) margin and image-guided radiotherapy frequency in head and neck (H&N) cancer treated with intensity-modulated radiotherapy (IMRT) assessed by kV cone-beam computed tomography (CBCT). Methods: We analyzed 360 CBCTs in 60 patients with H&N cancer treated with IMRT. The target delineation was contoured according to ICRU62. PTVs were generated by adding a 3-5 mm margin in all directions to the respective clinical target volumes. The kV CBCT images were obtained at first three days of irradiation and weekly thereafter. The overall mean displacement, range, systematic (${\Sigma}$) and random (${\sigma}$) errors were calculated. Adequate PTV margins were calculated according to the van Herk formula ($2.5{\Sigma}+0.7r$). Results: The mean of set-up errors was less than 2 mm in any direction. The overall frequency of set-up displacements greater than 3 mm was 3.9% in medial-lateral (ML) direction, 8% in superior-inferior (SI) direction, and 15.5% in anterior-posterior (AP) direction. The range of translations shifts was 0-9 mm in ML direction, 0-5 mm in SI direction and 0-10 mm in AP direction, respectively. After systematic set-up errors correction, the adequate margin to overcome the problem of set-up errors was found to be less than 3 mm. Conclusion: Image-guided kV CBCT was effective for the evaluation of set-up accuracy in H&N cancer. The kV CBCT at first three fractions and followed-by weekly appears adequate for reducing significantly set-up errors in H&N cancer treated with IMRT technique. Finally, 3-5 mm PTV margins appear adequate and safe to overcome the problem of set-up errors.