• Journal of Korean Clinical Health Science
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• v.5 no.4
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• pp.1021-1025
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• 2017

Purpose: Changes in corneal thickness after wearing hydrogel lens and silicone-hydrogel lens with different oxygen transmission rates wew syudied. Methods: Experiments were performed on 11 subjects(22 eyes). corneal thickness was measured after wearing contact lenses for 8 hours. Corneal thickness was measured using ORB Scan II(ver. 3.14) Results: In the results of the corneal thickness measurement by direction, in the case of the hydrogel-tor lens, the center thickness was $33.63{\mu}m$, the nasal was $34.29{\mu}m$, the temporal was $27.17{\mu}m$, the inferior was $27.17{\mu}m$, the superior was $18.90{\mu}m$, and change rates were 6.28%, 5.71%, 5.40%, 4.75% and 3.09%, respectively. In the results of the corneal thickness measurement by diameter, in the case of the hydrogel-tor lens, the center was $33.63{\mu}m$, the mid-peripheral was $28.19{\mu}m$, the peripheral was $24.18{\mu}m$, and change rates were 6.28%, 4.76%, and 3.79%, respectively. Conclusions: The hydrogel lenses with relatively low oxygen transmission rates resulted in a significant increase in thickness over the entire cornea compared to silicon-hydrogel lenses with high oxygen transmission rates.

• Archives of Plastic Surgery
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• v.38 no.4
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• pp.543-546
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• 2011

Purpose: LASIK, one of the currently popular ophthalmic procedures, can sometimes result in dry eye symptoms. In the patient who had underwent LASIK operation, the periorbital surgery may be more likely to lead to such a complication as dry eye symptom. We would like to report a case of corneal abrasion occurred after transconjunctival blepharoplasty in post-LASIK state and suggest the method about preventing the complication. Methods: A 30-year-old female patient underwent transconjunctival blepharoplasty and microfat graft into the face. She had history of LASIK operation 2 years ago. Corneal protector was applied to both eye during transconjunctival operation. After the surgery, she complained of visual blurring at left side. Ophthalmic examination revealed corneal abrasion of left eye. Results: Cornea protecting lens was applied to left eye for 2 weeks. Steroid and antibiotic eye drops were applied for relieving the symptoms and the prevention from progressing of complication. After 1 week, visual power and acuity was recovered to preoperative state. No other specific complications happened. Conclusion: Post-LASIK patient may have possibility of decreased corneal sensation and tear production. Preoperative ophthalmic examination is recommended for the prevention of complication. When corneal protector is applied, we suggest Optagel$^{(R)}$ as a useful lubricant.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.2
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• pp.223-232
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• 2012

Purpose: Validating a new research method to determine posterior corneal curvature and asphericity(Q) in vivo, based on measurements of anterior corneal topography and corneal thickness. Methods: Anterior corneal topographic data, derived from the Medmont E300 corneal topographer, and total corneal thickness data measured along the horizontal corneal meridian using the Holden-Payor optical pachometer, were used to calculate the anterior and posterior corneal apical radii of curvature and Q. To calculate accurate total corneal thickness the local radius of anterior corneal curvature, and an exact solution for the relationship between real and apparent thickness were taken into consideration. This method differs from previous approach. An elliptical curve for anterior and posterior cornea were calculated by using best fit algorism of the anterior corneal topographic data and derived coordinates of the posterior cornea respectively. For validation of the calculations of the posterior corneal topography, ten polymethyl methacrylate (PMMA) lenses and right eyes of five adult subjects were examined. Results: The mean absolute accuracy (${\pm}$standard deviation(SD)) of calculated posterior apical radius and Q of ten PMMA lenses was $0.053{\pm}0.044mm$ (95% confidence interval (CI) -0.033 to 0.139), and $0.10{\pm}0.10$ (95% CI -0.10 to 0.31) respectively. The mean absolute repeatability coefficient (${\pm}SD$) of the calculated posterior apical radius and Q of five human eyes was $0.07{\pm}0.06mm$ (95% CI -0.05 to 0.19) and $0.09{\pm}0.07$ (95% CI -0.05 to 0.23), respectively. Conclusions: The result shows that acceptable accuracy in calculations of posterior apical radius and Q was achieved. This new method shows promise for application to the living human cornea.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.1
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• pp.35-45
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• 2016

Purpose: The present study was aimed to investigate the effect of corneal eccentricity on the axial rotation when wearing toric soft contact lenses were worn for certain time and changing the gaze directions. Methods: Toric soft contact lenses with double thin zone design applied on 85 of with-the-rule astigmatic eyes. Then, rotational direction and amount of contact lenses were measured after 15 minutes and 6 hours of lens wear. The difference was further compared and analyzed according to corneal eccentricity. Results: The rotation of toric lens showed a tendency to rotate to temporal direction in all gaze directions except temporal-upper direction in all groups of corneal eccentricity. The amount of lens rotation in the frontal gaze direction exhibited a negative correlation since the amount was decreased with increasing corneal eccentricity after both 15 minutes and 6 hours of lens wearing. In many cases, the cornea with small eccentricity also showed the lens rotation larger than $10^{\circ}$. The difference in rotational amount after 15 minutes of toric lens wear was small according to the corneal eccentricity however, the change of rotational amount of contact lens according to corneal eccentricity was shown after 6 hours of lens wear. Conclusions: The present study revealed that the amount of axial rotation was largely varied according to the wearer's corneal eccentricity when wearing toric lens and the rotational amount after certain time of lens was also affected by corneal eccentricity. Thus, it is suggested that the selection of toric soft contact lenses based on corneal eccentricity is necessary.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.2
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• pp.143-151
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• 2012

Purpose: The present study was conducted to investigate whether there is any difference in the centration of spherical RGP lens on cornea according to corneal types, corneal astigmatism and lens fitting states. Methods: Spherical RGP lens was fitted on 29 eyes of round-typed cornea and 45 eyes of symmetric bowtie-typed cornea with 0.00~2.75 D of corneal astigmatism in alignment, steep or flat. Their lens centrations on cornea were analyzed by taking photographs. Results: The centration of spherical RGP lens in the vertical direction was decentrated to downward direction in all cases, and the degree of decentration was not consistent. The lens centration in horizontal direction was significantly more-decentrated to the temporal meridian as base curve of lens was increased, and the degree of decentration was different according to the corneal type, corneal astigmatism and fitting states. With the same degree of astigmatism, the lens decentration to the temporal meridian was bigger in round-typed cornea than that in symmetirc bowtie-typed cornea. Conclusions: The centration of spherical RGP lens varies depending on lens fitting states, corneal astigmatism, and corneal types. Thus, the consideration of these factors may improve the success rate in RGP lens prescription.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.2
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• pp.151-156
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• 2015

Purpose: This study has been compared the degree of corneal edema arising from the material of the lens after wearing the recommended wearing time for the contact lens. Methods: For the study, 43 adults of 77 eyes who did not use drugs and have not any disease participated. Three types of lenses including narafilcon A, HEMA, and silicone hydrogel material regular replaceable lenses were used. Central corneal thickness was measured before and after 8 hours from wearing lenses using Pentacam. The degree of corneal edema was determined by the difference before and after wearing. Results: The average corneal edema of narafilcon A, HEMA material lens, and silicone hydrogel material regular replaceable lens were $2.36{\pm}6.15{\mu}m(Mean{\pm}SD)$, $23.61{\pm}10.71{\mu}m$, $18.25{\pm}8.64{\mu}m$, respectively. The central corneal thickness after wearing narafilcon A was not statistically significant with the central corneal thickness before wearing the lens. Central corneal thickness before and after wearing HEMA material lens and silicone hydrogel material regular replaceable lens were statistically significant. Conclusions: The amount of corneal edema induced by silicone hydrogel material regular replaceable lens was no statistically significant difference to the amount of corneal edema induced by HEMA material lens, but there was significant difference to narafilcon A. Therefore, it is judged to be careful not to exceed the recommended wearing time depending on the composition of the contact lens material.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.4
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• pp.373-380
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• 2012

Purpose: The present study was performed to investigate a relationship between the stable centrations of spherical RGP lens and aspherical RGP lens on cornea and corneal eccentricity. Methods: Two RGP lenses with different designs were fitted in alignment, steep or flat on total 84 eyes having corneal eccentricity of 0.28~0.78. The stable centration of lenses on cornea was analyzed by taking photographs with a high-speed digital camera. Results: The stable centrations of spherical and aspherical RGP lenses in horizontal direction were decentrated to temporal side. More centration to median side was shown when corneal eccentricity was larger. The difference between the stable centrations of spherical and aspheric RGP lenses according to corneal eccentricity was bigger when the fitting state was flatter. The difference in the stable centrations of aspherical RGP lens was smaller than that of spherical RGP lens regardless of fitting status. The stable centrations of spherical and aspherical RGP lenses in vertical direction were located below corneal apex regardless of fitting status however, there was no significant difference analyzed by the variation of corneal eccentricity. However, there were many cases that RGP lenses were in upper eyelid with increasing corneal eccentricity. Conclusions: The consideration of corneal eccentricity is required for RGP lens fitting and manufacturing aspherical RGP lens since the stable centration of spherical RGP lens as well as aspherical RPG lens' centration was changed depending on corneal eccentricity.

• Journal of Veterinary Clinics
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• v.24 no.4
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• pp.557-562
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• 2007

This study was performed to investigate the signalment, cause and clinical feature of corneal diseases of dogs in Korea. One hundred eighty-four dogs(273 eyes) with corneal diseases were examined and classified into congenital, inflammatory and metabolic diseases. Inflammatory diseases were subclassified into nonulcerative keratitis and ulcerative keratitis. The most prevalent corneal disease type was inflammatory disease(93.7%) and nonulcerative keratitis(58.6%) is more prevalent than ulcerative keratitis(35.1%) in the inflammatory diseases. The main cause of nonulcerative keratitis was keratoconjunctivitis sicca(19.0%) whereas that of ulcerative keratitis was trauma(9.9%). The most common breed with corneal disease was Shih Tzu(49.5%). The affected mean age was $6.4{\pm}4.1$ years old. The prevalence rate of corneal diseases were slightly higher in female(56.8%) than in male(43.2%). The data of corneal diseases in dogs obtained from this study will be utilized in prevention, diagnosis and treatment of corneal diseases in dogs and client education.

• Biotechnology and Bioprocess Engineering:BBE
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• v.10 no.3
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• pp.262-269
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• 2005

Many researchers have employed cryopreserved amniotic membrane (CAM) in the treatment of a severely damaged cornea, using corneal epithelial cells cultured on an amniotic membrane (AM). In this study, two Teflon rings were made for culturing the cells on the LAM and CAM, and were then used to support the AM, which is referred to in this paper as an Ahn's AM supporter. The primary corneal epithelial cells were obtained from the limbus, using an ex-plantation method. The corneal epithelium could be reconstructed by culturing the third­passage corneal epithelial cells on the AM. A lyophilized amniotic membrane (LAM) has a higher rate of graft take, a longer shelf life, is easier to store, and safer, due to gamma irradiation, than a (AM. The corneal epithelium reconstructed on the LAM and (AM, supported by the two­Teflon rings, was similar to normal corneal epithelium. However, the advantages of the LAM over that of the (AM make the former more useful. The reconstruction model of the corneal epithelium, using AM, is considered as a good in vitro model for transplantation of cornel epithelium into patients with a severely damaged cornea.

• Journal of Korean Ophthalmic Optics Society
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• v.13 no.4
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• pp.151-154
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• 2008

Purpose: Javals' rule is a commonly used formula for estimating total astigmatism from corneal astigmatism. Many researchers suggested a modication of Javals' rule. Therefore, we estimated the total astigmatism on the basis of measurements of corneal astigmatism and assessed the accuracy of Javals' rule. Methods: We estimated the total astigmatism on the basis of measurements of corneal astigmatism on 108 eyes of 54 subjects of koreans in their twenties. Results: The regression of the total astigmatism from corneal astigmatism is less than 1.25 of Javals' rule, but it was equivalent to Auger's modified Javals' rule. Conclusions: The regression equation for this study was as follows: Total Astigmatism=0.79 (Corneal Astigmatism)-0.49D${\times}$90.