• Proceedings of the Korea Information Processing Society Conference
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• 2014.11a
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• pp.520-522
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• 2014

Due to the availability of easy-to-use and powerful image editing tools, the authentication of digital images cannot be taken for granted and it gives rise to non-intrusive forgery detection problem because all imaging devices do not embed watermark. Forgery detection plays an important role in this case. In this paper, an effective framework for passive-blind method for copy-move image forgery detection is proposed, based on Gabor filter which is robust to illumination, rotation invariant, robust to scale. For the detection, the suspicious image is selected and Gabor wavelet is applied from whole scale space and whole direction space. We will extract the mean and the standard deviation as the texture features and feature vectors. Finally, a distance is calculated between two textures feature vectors to determine the forgery, and the decision will be made based on that result.

• Journal of fish pathology
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• v.31 no.2
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• pp.101-107
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• 2018

Quantitative analysis of a myxosporean parasite, Parvicapsula sp. in internal organs (kidney, intestine, spleen, brain and liver) from non-emaciated (farm-A) or emaciated (farm-B and farm-C) olive flounder Paralichthys olivaceus were performed by real-time PCR. The highest DNA copy number ($1.7{\times}10^7copies/mg$ tissue) was detected in kidney of the emaciated olive flounder from farm-C, while the DNA copy number was below detection limit in all the organs of the olive flounder from farm-B. There was not positive result in all of organs from olive flounder in farm-A. PCR and histopathological analysis were also performed using the same specimen and showed same results as those by real-time PCR.

• Journal of Genetic Medicine
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• v.18 no.1
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• pp.31-37
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• 2021

Purpose: To summarize the results of chromosomal microarray analysis (CMA) for copy number variants (CNVs) detection and clinical utility in a single tertiary hospital. Materials and Methods: We performed CMA in 46 patients over the course of two years. Detected CNVs were classified into five categories according to the American College of Medical Genetics and Genomics guidelines and correlated with clinical manifestations. Results: A total of 31 CNVs were detected in 19 patients, with a median CNV number per patient of two CNVs. Among these, 16 CNVs were classified as pathogenic (n=3) or likely pathogenic (LP) (n=11) or variant of uncertain significance (n=4). The 16p11.2 deletion and 16p13.11 deletion classified as LP were most often detected in 6.5% (3/46), retrospectively. CMA diagnostic yield was 24.3% (9/37 patients) for symptomatic patients. The CNVs results of the commercial newborn screening test using next generation sequencing platforms showed high concordance with CMA results. Conclusion: CMA seems useful as a first-tier test for developmental delay with or without congenital anomalies. However, the classification and interpretation of CMA still remained a challenge. Further research is needed for evidence-based interpretation.

• Proceedings of the Korea Contents Association Conference
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• 2018.05a
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• pp.561-562
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• 2018

디지털 중합효소연쇄반응(Digital PCR)은 3세대 PCR로 명명하며, 1세대인 일반 PCR과 2세대인 정량 PCR(Real-time PCR)의 단점을 보완하여 개발된 방법이다. Digital PCR System은 소량의 PCR 반응을 10만개 이상의 반응통(wall)에 적재하는 방식의 나노유체칩에서 쪼개어 증폭시킨 후, target DNA를 계수한다. Target DNA의 증폭 여부에 따라 positive(1)와 negative(0)로 digital signal처럼 받아들여 계수하고, 포아송 분포를 통해 target DNA의 copy를 계산해 최종적으로 샘플 microlitr당 Copy수로 결과 값을 확인할 수 있다. 본 연구에서는 종(種)이 다른 동물의 조직이 서로 섞여있을 때 사람의 조직을 탐색하는 방법으로 유전자 증폭을 할 경우, digital PCR의 유효성에 대해 증명하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2012.06c
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• pp.19-21
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• 2012

모든 암 세포는 체세포 변이를 동반한다. 따라서 암 유전체 변이 분석에 의하여 암을 발생시키는 유전자 및 진단/치료법을 찾아낼 수 있다. 본 연구에서는 차세대 시퀀싱 데이터를 이용하여 암 특이적 단이 반복 변이(copy number variation, CNV) 유형을 밝히는 새로운 알고리즘을 제안한다. 제안하는 방식은 암 환자의 정상 세포와 암세포로부터 얻어진 정상 유전체와 암 유전체를 동시 분석하여 각각 CNV 후보 영역을 추출하며, 통계적 유의성 분석을 통하여 암 특이적 CNV 후보 영역을 선별하고, 다음 후처리 과정에서 참조 표준 서열(reference sequence)에 존재하는 오류 영역 보정 작업을 수행하여 정확한 암 특이적 CNV 영역을 추출해 낸다. 또한 다수의 대용량 유전체 데이터 동시 분석을 위하여 맵리듀스(MapReduce) 기법을 기반으로 하는 병렬 수행 알고리즘을 제안한다.

• Proceedings of the Korea Information Processing Society Conference
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• 2008.11a
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• pp.1012-1015
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• 2008

The packet capturing becomes a bottleneck in the network intrusion detection and monitoring system as the network performance developing. Many approaches, zero copy, interrupt coalescing and NAPI which attempt to improve packet capturing performance of Linux, are inefficient. PF_RING is a new type of network socket that dramatically improves the packet capture speed, but not perfect. This paper proposes some solutions which can improve the memory utilization and save some data copy time based on the commodity network adapters rather than on the commercial network adapters.

• Korean Journal of Ecology and Environment
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• v.56 no.1
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• pp.1-13
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• 2023

Targeting Microcystin (MC), which is most abundantly detected in the North-Han River water area, we analyzed the relationship between the MC biosynthesis gene (mcyA gene), cyanobacteria cell density, and MC concentration, derived an RNA-MC conversion formula, and derived the cyanobacteria. The concentration of MC present in cells was predicted. In the North-Han River waters, the mcyA gene was found mainly at downstream sites of the North-Han River after Muk-Hyeon Stream junction, and higher copy numbers were found on average than other sites. In the Uiam Lake waters upstream of the North-Han River, the mcyA gene copy number increased at the Kong-Ji Stream point, and after September, the mcyA gene copy number decreased throughout the North-Han River waters. The expression of the mcyA gene was concentrated in the short period of summer due to the spatio-temporal difference between upstream and downstream water bodies. The mcyA gene expression level was not only highly correlated with MC concentration, but also correlated with the cell density of Microcystis aeruginosa and Dolichospermum circinale, which are known to biosynthesize MC. Six conversion formulas derived based on the RNA-MC relationship showed statistical significance (p<0.05) and exhibited high correlation coefficients (r) of 0.9 or higher. The expression level of MC biosynthesis gene present in eRNA determines the synthesis of cyanotoxin substances in water, quickly quantifies gene activity, and can be fully utilized for early warning of MC development.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.2
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• pp.462-482
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• 2014

This paper proposes a new resampling detection method for images that detects whether an image has been resampled and recovers the corresponding resampling rate. The proposed method uses a given set of zeroing masks for various resampling factors to evaluate the convolution values of the input image with the zeroing masks. Improving upon our previous work, the proposed method detects more resampling factors by checking for some periodicity with an approximate detection mechanism. The experimental results demonstrate that the proposed method is effective and efficient.

• Proceedings of the Korea Society of Information Technology Applications Conference
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• 2005.11a
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• pp.319-323
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• 2005

As the software industry develops at a rate speed, anyone can copy or plagiarize without difficulty contents that are becoming digitalized. To make it worse, the development of various contents that be illegally copied and plagiarized are resulting in the increasing infringement on and the plagiarism of the intellectual property. This dissertation tries to put forth the method and the theory to effectively detect any plagiarism of the source code of programs realized in various languages. This dissertation analyzes the advantage and disadvantage of the plagiarism test software, and especially, presents a method to detect possible plagiarism by using the Pattern Matching to overcome its disadvantage. And it also intends to introduce more developed automatic detection system by overcoming the problems with the method of Pattern Matching.

• Proceedings of the KIEE Conference
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• 1998.11b
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• pp.606-608
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• 1998

Digital watermarking is the technique which embeds the invisible signal into multimedia data such as audio, video, images, for copyright protection, including owner identification and copy control information. In this paper, a new watermark detection algorithm by local masking cross covariance between watermarked signal and pseudo noise signal is proposed. The proposed algorithm enhances the detection probability for embedding information. Since reducing detection errors for the weak embedding signals, the algorithm improves the image quality and robusts against illegal attack to delete the embedding information and data compression applications such as JPEG and MPEGs.