• Radiation Oncology Journal
• /
• 제33권1호
• /
• pp.36-41
• /
• 2015

Purpose: To evaluate the incidence and risk factors of post-treatment intracranial hemorrhage of brain metastases from hepatocellular carcinoma (HCC). Materials and Methods: Medical records of 81 patients who have been diagnosed of brain metastases from HCC and underwent surgery, radiosurgery and/or whole brain radiotherapy (WBRT) between January 2000 and December 2013 were retrospectively reviewed. Results: Intracranial hemorrhage was present in 64 patients (79%) at the time of diagnosis. Median value of alpha-fetoprotein (AFP) level was 1,700 ng/mL. The Eastern Cooperative Oncology Group (ECOG) performance status for 20 patients was greater than 2. Fifty-seven patients underwent WBRT and the others were treated with surgery and/or radiosurgery without WBRT. During follow-up, 12 events of intracranial hemorrhage after treatment were identified. Three-month post-treatment hemorrhage rate was 16.1%. Multivariate analyses revealed that ECOG performance status, AFP, and WBRT were associated with post-treatment hemorrhage (p = 0.013, 0.013, and 0.003, respectively). Kaplan-Meier analysis showed that 3-month post-treatment hemorrhage rate of new lesion was higher in patients treated without WBRT, although statistical significance was not reached. (18.6% vs. 4.6%; p = 0.104). Ten of 12 patients with post-treatment hemorrhage died with neurologic cause. Conclusion: WBRT should be considered to prevent post-treatment hemorrhage in the treatment of brain metastases from HCC.

• Journal of Dairy Science and Biotechnology
• /
• 제33권3호
• /
• pp.203-207
• /
• 2015

본 연구에서는 동결건조 공정에 의한 유산균의 생균수 감소를 최소화 할 수 있는 농후 발효유를 개발하고자 하였다. 이를 위해 농후 발효유 제조에 첨가되는 당의 종류 및 구성을 달리하여 동결 건조 전후의 유산균 생존율을 비교 분석하였다. 그 결과, 포도당의 일부를 이소말토올리고당으로 대체하였을 때, 발효유 내 초기 유산균 생균수 및 동결건조 공정 이후의 유산균 생존율 또한 높아졌다. 또한 동결 건조 시 열판 온도가 낮을 경우, 건조 효율은 떨어지지만, 동결건조 이후의 동결건조 농후 발효유 내 초기 유산균 생존율이 높았다. 16주간의 저장기간에 따른 유산균 생균수 변화를 살펴본 결과, 상온보관 조건에서 유산균은 지수적으로 감소하였다. 하지만 16주가 경과한 후에도 $1.63{\times}10^8CFU/g$의 생균수를 유지하여 약 0.6 g 이상의 동결건조 농후 발효유만 섭취하여도 체내에서 유산균 증식 및 유해균 억제 배변활동 원활 등의 건강기능성을 가질 수 있는 수준이었다. 하지만 본 연구에서는 식품 매트릭스에 따른 동결방지 효과를 파악할 때, 유산균 생균수를 유일한 지표로 삼았다는데 한계가 있다. 유산균 생균수뿐만 아니라, 유산균의 활성을 살펴보기 위해 동결건조 이후의 젖산 생성능력이나 실질적으로 체내에 들어갔을 때 위액이나 담즙액에 대한 저항성 측면에서의 추가 연구가 필요할 것으로 사료된다.

• Asian-Australasian Journal of Animal Sciences
• /
• 제33권4호
• /
• pp.634-639
• /
• 2020

Objective: This study was conducted to investigate the effect of heating of foot-and-mouth disease (FMD) vaccine before injection, on the incidence of lesions at the injection site (pork butt), amount of discarded meat, and economical benefit. Methods: In total, 101,086 piglets raised in 30 farms, were vaccinated in the neck with 2 mL of FMD vaccine at 56 d and 84 d of age using a commercial syringe. The heat treatment group (48,511 pigs) was injected with the FMD vaccine after it had been heated in a water bath at 40℃ for 20 min. After slaughter, the incidence of lesions on the pork butt was inspected, and the subsequent amount of discarded meat was recorded. Results: Heat treatment of FMD vaccine reduced the incident rate of lesions on the pork butt (p<0.01). Overall, 17.81% of the pigs in the heat treatment group had lesions, while the incident rate in the control group was 21.70%. The amount of discarded meat per head of total pigs and per head of pigs with lesions were significantly lower in the heat treatment group than the control group (p<0.01). Thus, the proportion of discarded meat to dressed carcass was lower in the heat treatment group (0.249%) compared with the control group (0.338%) (p<0.01). Farms that rear 1,000 sows can gain 1,863,289 KRW (1,600 USD) in one year when they adopt heat treatment of FMD vaccine before injection. Conclusion: Heat treatment of FMD vaccine using simple heat equipment (water bath) can be effective in reducing lesions caused by FMD vaccination and increase the economic benefits in pig farms.

• 환경정책연구
• /
• 제2권1호
• /
• pp.51-75
• /
• 2003

The objective of this study is to analyze the problems of disposal and collection, including administrative management of agricultural PE waste and suggest effective management measurements. Information regarding problems of agricultural PE waste management were collected from field survey of farmers, regional governments and officials. On the national level, the low ratio of collection for optimal treatment of agricultural PE waste is a critical problem. , the negative discharging behavior of farmers, an illegal incineration and landfill of farmers and a lack of education and extension etc. An ambiguity of the management principle to agricultural PE waste, the differences in management among the regional governments, a lack of will of the regional governments and officials to realize SARD and lack of education and extension etc. are some of the problems in administrative management of agricultural PE waste collection. The major suggestions of this study are as follows : (1) to strengthen education and extension, (2) to adopt an improved economic incentive system and strong, lawful regulation simultaneously, (3) to use temporang collection and permanent collection site, and (4) to organize "OTC(Optimal Treatment Conference)" composed of farmers, regional cooperative, PE producers etc. for operating an effective management system.

• 대한장애인치과학회지
• /
• 제3권1호
• /
• pp.6-10
• /
• 2007

Many disabled patients need extensive dental treatment because they have much difficulty in maintaining their oral hygiene. However, because they are not cooperative and not manageable, they require physical restraints, drug induced sedation or general anesthesia. General anesthesia is useful in control of the patients who cannot be treated in other ways. Additionally, general anesthesia provides more safe environment for medically compromised patients. The aim of the present study was to investigate a kind of disorder, sources of referral, preoperative oral condition, experience of dental visit, and performing general anesthesia or not of 930 disabled patients in Kyung-Hee University dental hospital for 30 years.

• Korean Journal of Acupuncture
• /
• 제32권4호
• /
• pp.208-212
• /
• 2015

Objectives : We present a successful administration of acupuncture in alleviating persistant peripheral neuropathy due to bortezomib, a potent therapeutic agent of mutlple myeloma. Methods : A patient, experiencing numbness, coldness, tingling and weakness in her feet and hands after bortezomib treatment, was administered acupuncture for 32 weeks, 3 times/week for first 4 weeks and 2 times/week the last 28 weeks, in bilateral acupuncture points, ST36, ST40, EX-LE10, LI11, TE5, and EX-UE9. Responses were assessed at the end of every 4 weeks with Eastern Cooperative Oncology Group(ECOG) grading system, National Cancer Institute - Common Toxicity Criteria(NCIC-CTC) v4.0, Numeric Rating Scale(NRS) 0-10, and Neuropathy Pain Scale (NPS). Results : ECOG was improved from 2 to 1, NCIC-CTC from 2 to 1, NRS from 8 to 1, and NPS from 41 to 5 through 32 weeks of acupuncture treatment. Conclusions : It is conceivable that acupuncture can be a help to relieve bortezomib induced peripheral neuropathy.

• Journal of Hospice and Palliative Care
• /
• 제19권3호
• /
• pp.256-261
• /
• 2016

방사선치료는 암과 관련된 증상을 완화시키는 목적으로 자주 사용되고 있다. 정확하고 안전한 방사선치료를 받기 위해서는 방사선이 나오는 동안 치료 테이블 위에 가만히 누워 있어야 한다. 그러나 일부 환자는 기질적인 문제 외에 심리적인 문제에서 기인한 증상으로 인해 가만히 누워 있지 못한다. 이 논문에서는 모의치료 단계 전부터 치료 테이블에 바로 누워 있지 못했지만 별 다른 장소에서의 교육 참여 없이 침상에서 쉽게 할 수 있는 이완요법을 배워 방사선치료 하는 동안 가만히 누워 있는 게 가능했던 두 명의 말기암환자 사례를 보고하고자 한다.

• 한국환경과학회지
• /
• 제32권10호
• /
• pp.741-744
• /
• 2023

This study focused on high school laboratory research and the main purpose was to develop alternative additives for livestock waste and ammonia volatilization methods with high school students as participants and to provide information to business owners based on the results. Compared to the control groups, The bentonite and illite treatment groups had similar ammonia volatilization, pH, EC, and total nitrogen content. In particular, the alum and aluminum chloride mixed treatment group showed low pH and ammonia volatilization, and high EC and total nitrogen content for poultry litter. As a result, when focusing on high school laboratory research, the alum and aluminum chloride mixed agent treatment fulfilled its role as an alternative additive for ammonia reduction. In addition, this approach can be suggested as a method to solve difficulties in adapting to the field through a practical cooperative relationship with livestock farms.

• 대한한의학회지
• /
• 제40권2호
• /
• pp.72-88
• /
• 2019

Objectives: The purpose of this study is to understand the experience of traffic accident patients with serious injury treated with Traditional Korean Medicine (TKM). Methods: This study was conducted on the basis of grounded theory. We recruited 10 participants who had been hospitalized in Dongguk University Bundang Oriental Hospital after traffic accident. Raw data was collected by in-depth interview, and analyzed by using constant comparison. The coding(open-axial-selective) was performed in order to create paradigm and theoretical model, which can explain main theme of this study. Results: Core phenomenon of this study was 'Experiencing TKM treatment as an alternative' and core category was 'Searching for the answer to the management of traffic accident sequela through TKM treatment' Conclusions: For patients with serious injury, 'Experiencing TKM treatment as an alternative' has meaning as the following: First, The absence of accurate radiography and surgical management makes it hard for patients to choose Korean medicine hospital immediately after traffic accident. Second, Effectiveness of TKM treatment should be evaluated in the long term. Third, TKM treatment is superior to Western medicine treatment in managing long-term patients who suffered from serious injury involved in traffic accident. Finally, Cooperative service of the Western medicine and TKM will provide more satisfactory medical care for traffic accident patients.

• 대한한방부인과학회지
• /
• 제36권2호
• /
• pp.36-54
• /
• 2023

Objectives: This study was aimed to develop a Korean Medicine (KM) clinical practice guideline (CPG) of Nausea and Vomiting of Pregnancy (NVP). Methods: We conducted a questionnaire survey targeting KM doctors belonging to the Association of Korean Medicine by e-mail. We received 1,023 responds, and analyzed the answers. Results: 1. 83.0% of respondents knew the concepts and contents of CPG, and 98.1% had practical use plan. 2. 82.1% of respondents used pattern identification diagnosis for NVP patients, and the most commonly diagnosed pattern was spleen-stomach weakness (脾胃虛弱) with 41.3%. 3. The most frequently used treatment for NVP patients was KM combined treatment (46.7%). Herbal medicine+acupuncture (46.8%) was most used among KM combined treatments, and herbal medicine (37.1%) was most used among KM single treatments. 4. Among the contents of CPG for NVP, the fields of interest were selected in the order of KM treatment, KM-Western medicine cooperative treatment, KM diagnosis, prevention and regimen management. In the 'diagnosis part', the use of the symptom evaluation scale questionnaire was 41.8%, higher than the KM pattern diagnosis (34.4%). In the 'treatment part', herbal medicine accounted for 33.8%, higher than that of acupuncture (including electro-acupuncture) at 23.7%. 5. As for the expected development effects, opinions on evidence-based, safety, clinical use, and standardization were the most common. Conclusions: We figured out KM doctors' recognition of KM clinical practice guideline, clinical diagnosis, treatment on NVP to make the contents of the CPG reflecting the clinical situation.