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http://dx.doi.org/10.14406/acu.2015.024

A Case Report of Long-term Acupuncture Treatment in Bortezomib Induced Peripheral Neuropathy  

Kim, So Yeon (School of Korean Medicine, Pusan National University)
Choi, Jun Yong (School of Korean Medicine, Pusan National University)
Yun, Young Ju (School of Korean Medicine, Pusan National University)
Park, Seong Ha (School of Korean Medicine, Pusan National University)
Han, Chang Woo (School of Korean Medicine, Pusan National University)
Publication Information
Korean Journal of Acupuncture / v.32, no.4, 2015 , pp. 208-212 More about this Journal
Abstract
Objectives : We present a successful administration of acupuncture in alleviating persistant peripheral neuropathy due to bortezomib, a potent therapeutic agent of mutlple myeloma. Methods : A patient, experiencing numbness, coldness, tingling and weakness in her feet and hands after bortezomib treatment, was administered acupuncture for 32 weeks, 3 times/week for first 4 weeks and 2 times/week the last 28 weeks, in bilateral acupuncture points, ST36, ST40, EX-LE10, LI11, TE5, and EX-UE9. Responses were assessed at the end of every 4 weeks with Eastern Cooperative Oncology Group(ECOG) grading system, National Cancer Institute - Common Toxicity Criteria(NCIC-CTC) v4.0, Numeric Rating Scale(NRS) 0-10, and Neuropathy Pain Scale (NPS). Results : ECOG was improved from 2 to 1, NCIC-CTC from 2 to 1, NRS from 8 to 1, and NPS from 41 to 5 through 32 weeks of acupuncture treatment. Conclusions : It is conceivable that acupuncture can be a help to relieve bortezomib induced peripheral neuropathy.
Keywords
acupuncture; bortezomib; peripheral neuropathy; multiple myeloma;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
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1 Mandiroglu S, Cevik C, Ayli M. Acupuncture for neuropathic pain due to bortezomib in a patient with multiple myeloma. Acupunct Med. 2014 ; 32(2) : 194-6.   DOI
2 Bao T, Medeiros M, Zhang R, Dorsey SG, Badros A. Improvement of Painful Bortezomib-Induced Peripheral Neuropathy Following Acupuncture Treatment in a Case Series of Multiple Myeloma Patients. Med Acupunct. 2012 ; 24(3) : 181-7.   DOI
3 Bao T, Goloubeva O, Pelser C, Porter N, Primrose J, Hester L, et al. A pilot study of acupuncture in treating bortezomib-induced peripheral neuropathy in patients with multiple myeloma. Integr Cancer Ther. 2014 ; 13(5) : 396-404.   DOI
4 Eastern Cooperative Oncology Group. ECOG Performance Status. [cited 2015 Oct 25]. Available from: http://ecog-acrin.org/resources/ecog-performance-status
5 National Cancer Institute. Common Terminology Criteria for Adverse Events (CTCAE) v4.0. [cited 2015 Oct 25]. Available from: http://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03_2010-06-14_QuickReference_5x7.pdf
6 National Institutes of Health - Warren Grant Magnuson Clinical Center. Pain Intensity Instruments. [cited 2015 Oct 25]. Available from: http://www.webcitation.org/6Ag75MDIq
7 Galer BS, Jensen MP. Development and preliminary validation of a pain measure specific to neuropathic pain: the Neuropathic Pain Scale. Neurology. 1997 ; 48(2) : 332-8.   DOI
8 Han Y, Smith MT. Pathobiology of cancer chemotherapy- induced peripheral neuropathy (CIPN). Front Pharmacol. 2013 ; 4 : 156.
9 Wong R, Sagar S. Acupuncture treatment for chemotherapy- induced peripheral neuropathy--a case series. Acupuncture in medicine. 2006 ; 24(2) : 87-91.   DOI
10 Donald GK, Tobin I, Stringer J. Evaluation of acupuncture in the management of chemotherapy-induced peripheral neuropathy. Acupunct Med. 2011 ; 29(3) : 230-3.   DOI
11 Schroeder S, Meyer-Hamme G, Epplee S. Acupuncture for chemotherapy- induced peripheral neuropathy (CIPN): a pilot study using neurography. Acupunct Med. 2012 ; 30(1) : 4-7.   DOI
12 Yoon J, Jeon JH, Lee YW, Cho CK, Kwon KR, Shin JE, et al. Sweet bee venom pharmacopuncture for chemotherapy-induced peripheral neuropathy. J Acupunct Meridian Stud. 2012 ; 5(4) : 156-65.   DOI
13 Rostock M, Jaroslawski K, Guethlin C, Ludtke R, Schroder S, Bartsch HH. Chemotherapy-induced peripheral neuropathy in cancer patients: a four-arm randomized trial on the effectiveness of electroacupuncture. Evid Based Complement Alternat Med. 2013 ; 2013 : 349653.
14 Franconi G, Manni L, Schroder S, Marchetti P, Robinson N. A systematic review of experimental and clinical acupuncture in chemotherapy-induced peripheral neuropathy. Evid Based Complement Alternat Med. 2013 ; 2013 : 516916.
15 Han CW. Acupuncture in chemotherapy-induced peripheral neuropathy : a review. Journal of PNU Korean Medicine Hospital. 2014 ; 3 :1-6.
16 Becker N. Epidemiology of multiple myeloma. Recent Results Cancer Res. 2011 ; 183 : 25-35.   DOI
17 Argyriou AA, Iconomou G, Kalofonos HP. Bortezomib-induced peripheral neuropathy in multiple myeloma: a comprehensive review of the literature. Blood. 2008 ; 112(5) : 1593-9.   DOI
18 Cavaletti G, Jakubowiak AJ. Peripheral neuropathy during bortezomib treatment of multiple myeloma: a review of recent studies. Leuk Lymphoma. 2010 ; 51(7) : 1178-87.   DOI
19 Cata JP, Weng HR, Burton AW, Villareal H, Giralt S, Dougherty PM. Quantitative sensory findings in patients with bortezomib- induced pain. J Pain. 2007 ; 8(4) : 296-306.   DOI
20 Bao T, Zhang R, Badros A, Lao L. Acupuncture treatment for bortezomib-induced peripheral neuropathy: a case report. Pain Res Treat. 2011 ; 2011 : 920807.