• 제목/요약/키워드: convergent response

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The safety, immunological benefits, and efficacy of ginseng in organ transplantation

  • Lim, Sun Woo;Luo, Kang;Quan, Yi;Cui, Sheng;Shin, Yoo Jin;Ko, Eun Jeong;Chung, Byung Ha;Yang, Chul Woo
    • Journal of Ginseng Research
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    • 제44권3호
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    • pp.399-404
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    • 2020
  • Korean ginseng (Panax ginseng) is associated with a variety of therapeutic effects, including antioxidative, anti-inflammatory, vasorelaxative, antiallergic, antidiabetic, and anticancer effects. Accordingly, the use of ginseng has reached an all-time high among members of the general public. However, the safety and efficacy of ginseng in transplant recipients receiving immunosuppressant drugs have still not been elucidated. Transplantation is the most challenging and complex of surgical procedures and may require causation for the use of ginseng. In this regard, we have previously examined the safety, immunological benefits, and protective mechanisms of ginseng with respect to calcineurin inhibitor-based immunosuppression, which is the most widely used regimen in organ transplantation. Using an experimental model of calcineurin inhibitor-induced organ injury, we found that ginseng does not affect drug levels in the peripheral blood and tissue, favorably regulates immune response, and protects against calcineurin inhibitor-induced nephrotoxicity and pancreatic islet injury. On the basis of our experimental studies and a review of the related literature, we propose that ginseng may provide benefits in organ transplant recipients administered calcineurin inhibitors. Through the present review, we aimed to briefly discuss our current understanding of the therapeutic benefits of ginseng related to transplant patient survival.

Electromagnetic Penetration into an Annular Aperture in a Thick Conductor

  • Lee Haeng-Seon
    • Journal of electromagnetic engineering and science
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    • 제5권3호
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    • pp.146-151
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    • 2005
  • Electromagnetic penetration into an annular aperture in a thick conducting plane is investigated with the integral transform and eigen-function expansion method. The solution is analytic and is represented in rapidly-convergent series which is amenable to numerical analysis. Numerical computations shows that apertures with narrow annular gap have sharp transmit power peaks in frequency response.

Social Distance of Affective Advice: The Role of Construal Level in Acceptance of Rational and Emotional Advice

  • Li, Lu
    • 예술인문사회 융합 멀티미디어 논문지
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    • 제7권4호
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    • pp.395-402
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    • 2017
  • Social network service provides an excellent platform for people seeking for advices. This research analyzed the effect of rational and emotional response and social distance on people's acceptance for advices online by the construal level theory. An experiment was completed to test the relationship between advisers and questioners and verify the content of online feedback would influence people's acceptance for advices on social network site. The online response included emotional advice and rational advice. Social distance between advisers and questioners was divided to close social distance condition and distant social distance condition. The study showed: (1) comparing with emotional advice, rational advice had a higher persuasive effect in both close and distant social distance conditions; (2) the impact of feedback from people with close social distance was stronger than the impact of the advices from people with distant social distance; (3) there existed an interaction effect between social distance and affective advice. The results revealed that the adviser's affective expression and relationship with the questioner would interactively impact the online persuasive effect.

Sensory Inputs to Upper Cervical Spinal Neurons Projecting to Midbrain in Cats

  • Kim, Jong-Ho;Jeong, Han-Seong;Park, Jong-Seong;Kim, Jong-Keun;Park, Sah-Hoon
    • The Korean Journal of Physiology and Pharmacology
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    • 제2권1호
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    • pp.9-19
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    • 1998
  • The present study was primarily carried out to characterize the properties of the spinomesencephalic tract (SMT) neurons that project from the upper cervical spinal segments to the midbrain. It was also investigated whether these neurons received convergent afferent inputs from other sources in addition to cervical inputs. Extracellular single unit recordings were made from neurons antidromically activated by stimulation of midbrain. Recording sites were located in lamina $I{\sim}VIII\;of\;C1{\sim}C3$ segments of spinal cord. Receptive field (RF) and response properties to mechanical stimulation were studied in 71 SMT neurons. Response profiles were classified into six groups: complex (Comp, n=9), wide dynamic range (WDR, n=16), low threshold (LT, n=5), high threshold (HT, n=6), deep/tap (Deep, n=10), and non- responsive (NR, n=25). Distributions of stimulation and recording sites were not significantly different between SMT groups classified upon their locations and/or response profiles. Mean conduction velocity of SMT neurons was $16.7{\pm}1.28\;m/sec$. Conduction velocities of SMTs recorded in superficial dorsal horn (SDH, n=15) were significantly slower than those of SMTs recorded in deep dorsal horn (DDH, n=18), lateral reticulated area (LRA, n=21), and intermediate zone and ventral horn (IZ/VH, n=15). Somatic RFs for SMTs in LRA and IZ/VH were significantly larger than those in SDH and DDH. Five SMT units (4 Comps and 1 HT) had inhibitory somatic RFs. About half (25/46) of SMT units have their RFs over trigeminal dermatome. Excitabilities of 5/12 cells and 9/13 cells were modulated by stimulation of ipsilateral phrenic nerve and vagus nerve, respectively. These results suggest that upper cervical SMT neurons are heterogenous in their function by showing a wide range of variety in location within the spinal gray matter, in response profile, and in convergent afferent input.

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PMSM의 약자속 제어 시 과변조 성능 개선을 통한 토크 응답 특성 향상 (Enhancement of Torque Response through Improvement of Overmodulation Performance in the Flux-weakening Control of PMSMs)

  • 정혜인;김상훈
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2019년도 전력전자학술대회
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    • pp.408-409
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    • 2019
  • PMSM(Permanent Magnet Synchronous Motor)의 약자속 제어 시 인버터를 6-스텝 모드까지 운전함으로써 전동기의 출력 토크 능력을 최대로 활용할 수 있다. 그러나 6-스텝 동작을 위해 일반적으로 사용되는 정적 과변조 기법의 경우 구현이 복잡하며, 과도 상태에서의 동작이 고려되지 않기 때문에 토크 응답 특성이 저하된다. 이에 비해 구현이 간단한 동적 과변조 기법을 사용하는 경우 전압변조지수 증가에 따라 인버터의 전압 이득이 1보다 비선형적으로 크게 작아지기 때문에 6-스텝 모드에서의 운전이 힘들다. 이에 본 논문에서는 구현이 용이한 동적 과변조 기법에 대해 과변조 성능이 향상되도록 하는 방법을 제안하며, 제안된 방법에 의해 인버터가 6-스텝 모드까지 운전될 수 있으므로 구동 전동기의 출력 토크 능력을 최대한으로 활용할 수 있으며, 향상된 토크 응답 특성을 얻을 수 있다.

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선박 구조물의 저진동 설계를 위한 새로운 조합 유전 알고리듬 개발 (Development of the New Hybrid Evolutionary Algorithm for Low Vibration of Ship Structures)

  • 공영모;최수현;송진대;양보석
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2006년도 춘계학술대회논문집
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    • pp.164-170
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    • 2006
  • 본 연구는 유전 알고리듬, 타부탐색법 그리고 반응표면법등 최근 많이 사용하고 있는 프로그램들의 장점들을 결합한 새로운 조합 유전 알고리듬을 제안한다. 본 알고리듬은 반응표면법 및 심플렉스법을 사용하여 유전알고리듬의 약점으로 여겨지는 수렴속도를 항상시키도록 하였다. 또한 유전 알고리듬에서 램덤한 다양성을 제공하지만, 본 연구에서는 타부리스트를 이용하여 체계적인 다양성을 추구하도록 하였다. 그리고 전통적인 시험함수에 본 알고리듬을 적용함으로써 본 방법의 효율성을 입증하였고 그 결과를 유전 알고리듬의 결과와 비교하였다. 또한 새롭게 제안된 알고리듬을 선미부에 위치한 청수탱크의 중량최적화에 적용한 길과 전역최적해를 효율적으로 찾는 것을 입증하였다. 또한 반응표면법을 사용한 새로운 유전알고리듬의 경우 실제 추가적인 목적함수를 평가하기 위한 계산이 필요 없으므로 수렴속도가 일반 유전 알고리듬보다 향상 되었음을 알 수 있었다. 마지막으로 제안된 조합 유전 알고리듬은 전역탐색능력과 수렴속도 측면에서 매우 강력한 전역 최적화 알고리듬임을 알 수 있었다.

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선박 구조물의 저진동 설계를 위한 새로운 조합 유전 알고리듬 개발 (Development of the New Hybrid Evolutionary Algorithm for Low Vibration of Ship Structures)

  • 공영모;최수현;송진대;양보석
    • 한국소음진동공학회논문집
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    • 제16권6호
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    • pp.665-673
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    • 2006
  • 이 연구는 유전 알고리듬, 타부탐색법 그리고 반응표면법등 최근 많이 사용하고 있는 프로그램들의 장점들을 결합한 새로운 조합 유전 알고리듬을 제안한다. 이 알고리듬은 반응표면법 및 심플렉스법을 사용하여 유전알고리듬의 약점으로 여겨지는 수렴속도를 항상 시키도록 하였다. 또한 유전 알고리듬에서 램덤 한 다양성을 제공하지만, 이 연구에서는 타부리스트를 이용하여 체계적인 다양성을 추구하도록 하였다. 그리고 전통적인 시함함수에 본 알고리듬을 적용함으로써 이 방법의 효율성을 입증하였고 그 결과를 유전 알고리듬의 결과와 비교하였다. 또한 새롭게 제안된 알고리듬을 선미부에 위치한 청수탱크의 중량최적화에 적용한 결과 전역 최적해를 효율적으로 찾는 것을 입증하였다. 또한 반응표면법을 사용한 새로운 유전알고리듬의 경우 실제 추가적인 목적함수를 평가하기 위한 계산이 필요 없으므로 수렴속도가 일반 유전 알고리듬보다 향상되었음을 알 수 있었다. 마지막으로 제안된 조합 유전 알고리듬은 전역탐색능력과 수렴속도 측면에서 매우 강력한 전역 최적화 알고리듬임을 알 수 있었다.

Torsional flexural steady state response of monosymmetric thin-walled beams under harmonic loads

  • Hjaji, Mohammed A.;Mohareb, Magdi
    • Structural Engineering and Mechanics
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    • 제52권4호
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    • pp.787-813
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    • 2014
  • Starting with Hamilton's variational principle, the governing field equations for the steady state response of thin-walled beams under harmonic forces are derived. The formulation captures shear deformation effects due to bending and warping, translational and rotary inertia effects and as well as torsional flexural coupling effects due to the cross section mono-symmetry. The equations of motion consist of four coupled differential equations in the unknown displacement field variables. A general closed form solution is then developed for the coupled system of equations. The solution is subsequently used to develop a family of shape functions which exactly satisfy the homogeneous form of the governing field equations. A super-convergent finite element is then formulated based on the exact shape functions. Key features of the element developed include its ability to (a) isolate the steady state response component of the response to make the solution amenable to fatigue design, (b) capture coupling effects arising as a result of section mono-symmetry, (c) eliminate spatial discretization arising in commonly used finite elements, (d) avoiding shear locking phenomena, and (e) eliminate the need for time discretization. The results based on the present solution are found to be in excellent agreement with those based on finite element solutions at a small fraction of the computational and modelling cost involved.

The Influence of Likert Scale Format on Response Result, Validity, and Reliability of Scale -Using Scales Measuring Economic Shopping Orientation-

  • Kim, Sae-Hee
    • 한국의류학회지
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    • 제34권6호
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    • pp.913-927
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    • 2010
  • This study investigates the influence of Likert scale formats such as the number of response categories and the inclusion of a mid-point from a methodological point of view using instruments that measure a fashionmarketing-related subject. Using a self-administered questionnaire, 201 respondents rated their economic clothing shopping orientation on three formats of scales that differed only in the number of response categories (ranging from 5 to 7) from February 8 to February 12, 2010. Descriptive statistics, Spearman's rank order correlation, t-test, exploratory factor analysis, confirmatory factor analysis, Pearson's correlation, and Cronbach's alpha were used in the analysis. The results are as follows. First, three scale formats were generally suitable for use due to validity and reliability. Second, the response results varied with the number of categories and the inclusion of a mid-point, although the differences were statistically insignificant (with only a few cases that differed). Third, construct validity was more secure in scales with fewer categories, whereas convergent and discriminant validity was generally good in all scale formats. Fourth, reliability coefficients were higher in scales with more categories. Fifth, the number of categories was of greater importance to instrument design than the inclusion of a mid-point. Implications for appropriate scale designs are suggested in this study.

비선형 약산법들에 의한 전단형 건물의 지진응답평가 (The Seismic Response Evaluation of Shear Buildings by Various Approximate Nonlinear Methods)

  • 김재웅;강병두;전대한
    • 한국지진공학회논문집
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    • 제9권5호
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    • pp.75-86
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    • 2005
  • 성능에 기초한 설계법에서는 비선형 응답산정이 필수적이다. 이를 위한 해석법으로는 비선형 시간이력해석, 비선형 정적해석 혹은 비선형의 영향을 고려한 등가정적해석 등이 있다. 비선형 응답을 산정하기 위한 가장 정확한 해석방법은 비선형 시간이력해석법이지만, 많은 시간과 노력을 필요로 한다. 비선형 직접스펙트럼법은 pushover곡선으로부터 구조물의 선형 진동주기와 항복강도를 구한 다음, 반복계산 없이 비선형 응답을 직접 산정하는 약산법이다. 본 연구에서는 비선형 약산법들의 정확성과 신뢰성을 다양한 지진과 전단형 건물의 여러 가지 조건에 대해 검토하고자 한다. 본 연구의 결론은 다음과 같다. 1) 선형 능력스펙트럼법에 의한 약산응답들은 수렴하는 해를 구하지 못하거나 발산하는 경우가 발생하며 수렴하더라도 큰 오차가 발생하는 경우가 있으며, 지진별로 오차의 편차가 크다. 2) 비선형 능력스펙트럼법은 능력스펙트럼법보다 계산량이 크게 줄어들고, 해는 구해지나 요구곡선의 특성으로 정확한 해를 구하기 어려울 수 있으며, 전반적으로 큰 오차가 발생한다. 3) 비선형 직접스펙트럼법은 다른 약산법들에 비해 추가적이고 반복적인 계산과정 없이 pushover곡선과 비선형 응답스펙트럼으로부터 비교적 정확한 값을 직접 구할 수 있으므로 실용적인 방법으로 사료된다.