• Asian-Australasian Journal of Animal Sciences
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• v.15 no.10
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• pp.1428-1432
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• 2002

Thirty-six (20 wethers and 16 rams) adult Gansu highland finewool sheep with an average liveweight of $19.42{\pm}1.83kg$ were used. The sheep were allocated to 4 treatments and confined in individual feeding stalls. The 80 day feeding trial was divided into 2 periods of 38 and 42 days. The sheep had access to clean water and were fed chopped wheat straw ad libitum. Daily supplemented diets of 150 g for the first period and 200 g for the later period were provided. The 4 types of supplements were: Wheat bran type (I), which is the traditional feeding practice in the area and the control group; Linseed cake type (II); Linseed cake+poultry litter type (III); Poultry litter+distiller grains type (IV). The digestibility trial was conducted using a total collection method at the end of the first period in the feeding trial. The results showed that the digestibilities of DM, OM, CP, CF, NDF and ADF in group II and III were increased to more than 50%. CP and NDF digestibility in group II were significantly increased by 23.6% and 25.5% respectively over group I (p<0.01) and by 10.1% and 13.1% respectively over group III (p<0.05). The digestibility of DM, OM, CP, CF, NDF and ADF in group IV was lower than group I by 4.4 to 8.4% (p>0.05). Compared to group I, group II and III increased straw intake by 17.6% (p<0.01) and 10.8% (p<0.05). The ADG increased from 16.2 g in group I to 45.3 g and 32.8 g (p<0.01) in group II and III respectively. The ratio of supplement intake to gain decreased from 10.7 in group I to 3.9 and 5.4 (p<0.01) in group II and III respectively. The ratio of supplement cost to gain also decreased by 60.0% and 64.3%, respectively. The wool growth rate and wool strength in these 2 groups were noticeably improved. This significantly enhanced the wool's textile value. The above parameters in group IV were lower than in group I, except the ratio of supplement cost to gain. This research indicates that local low quality nitrogen resources could be used effectively and economically to improve the utilization of wheat straw fed to sheep on smallholder farms under harsh loess plateau conditions in the winter.

• Korean journal of applied entomology
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• v.39 no.2
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• pp.73-82
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• 2000

Two Psyllidae species of Cacopsylla pyricola (Foerster) and C. pyrisuga (Foerster)damaging pear trees have been reported in Korea. However, their ecological characteristics and damagepatterns have not been evaluated yet. To establish basic control measures of C. pyricola, field phenology,overwintering ecology, seasonal fluctuation and temperature-dependent development of C. pyricola wereexamined. C. pyricola overwintered under the bark scale of pear trees as winter form adults and theymoved to fruiting twigs from mid-February. Honeydew produced by C. pyricola nymphs and adults asthey feed caused serious black sooty mold on leaves and fruits. The seasonal occurrence of C. pyricolawas different every year. In 1993, characterized by cold temperature and heavy precipitation, C. pyricolapopulation was maintained highly during growing season. However, the population was decreased rapidlyfrom early July in 1994, year of hot and dry weather condition. In 1995, year of average temperature, thedensity of C. pyricola population was decreased during hot months of July and August, and rebuilt up inSeptember and October. The development periods of C. pyricola eggs were 13.33 days at 15"C, 9.32 daysat 20$^{\circ}$C, 7.82 days at 25"C, 6.60 days at 30$^{\circ}$C, and 7.75 days at 35$^{\circ}$C. The development periods ofnymphs were 33.75 days at 15OC, 23.77 days at 20$^{\circ}$C, 15.21 days at 25"C, and 17.40 days at 30$^{\circ}$C. Theirdevelopment periods and mortalities were increased in higher temperatures. The parameters of nonlineardevelopment model, Weibull and linear development models of Cacopsylla pyricola were estimated.models of Cacopsylla pyricola were estimated.

• Korean Journal of Food Science and Technology
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• v.52 no.1
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• pp.26-30
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• 2020

This study was undertaken to determine the characteristics of xanthoangelol, the major chalcone constituent derived from the extracts of different parts of Lespedeza bicolor. Xanthoangelol was isolated from the root extract using column chromatography and used as a standard for quantitative analysis. The structure of the isolated compound was established based on spectroscopic evidence. The HPLC-DAD method was validated for specificity, linearity, precision, accuracy, limit of detection, and limit of quantitation. The calibration curve of xanthoangelol had significant linearity (R²>0.9999). Limit of detection and limit of quantitation 0.018 and 0.059 ㎍/mL, respectively. The relative standard deviation values of precision test, and intra- and inter-day tests were less than 0.22 and 0.40%, respectively. In the recovery test, the accuracy ranged from 98.98-102.78% with RSD values less than 0.13%. The method validation parameters indicate the applicability of the HPLC method for quality control of food or drug formulations containing L. bicolor.

• Science of Emotion and Sensibility
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• v.13 no.4
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• pp.721-732
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• 2010

As increasing of electrical device usage, social concerns about the possible effects of 60Hz electromagnetic fields (EMF) on human health have increased. The number of people with self-attributed electromagnetic hypersensitivity (EHS) who complain of subjective symptoms such as headache, insomnia etc. also increased. However, we don't know whether the EHS results from psychological factor or real perception to the electromagnetic field. In this study, we simultaneously investigated physiological changes(heart rate, respiration rate, heart rate variability, alpha and beta waves in EEG), subjective symptoms and perception accuracy to assess origins of subjective symptoms according to the EMF exposure. Experiment consists of real and sham sessions and 60Hz 12.5uT magnetic field was on(real) or off(sham) to 15 EHS and 16 nonEHS. As the results, EMF exposure did not have any effects on physiological parameters or subjective symptoms for both groups. There was also no evidence that EHS group perceived the EMFs correctly than the control group. Therefore, the origins of subjective symptoms is not the 60Hz magnetic field but psychological factors.

• Journal of Oriental Neuropsychiatry
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• v.26 no.2
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• pp.89-102
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• 2015

Objectives: To examine the medical effectiveness of meditation programs ($\alpha$ version) by psychological types. Methods: MBTI, which was created by Katharine Cook Briggs and Isabel Briggs Myers, was used as the Psychological Type test and to investigate psychological temperament and functions and psychological preferences. Heart rate variability was used to test the effectiveness of meditation by investigating time domains (mean HR, SDNN, PSI) and frequence domain parameters (TP, LF, HF, LF or HF norm, Ln (TP or VLF or LF or HF). Results: 1. The autonomic nervous system became active, and both time domains and frequency domains showed positive responses to meditation in heart rate variability tests, without distinction of Psychological Types. 2. In Psychological Types using sensing over intuition for perception, there were positive responses as well as an increase of the parasympathetic nervous system's activeness to meditation for heart rate variability tests, depending on psychological temperaments and psychological functions. 3. In heart rate variability tests by preferences, there was no difference. Extroversion and Introversion types, Sensing over Intuition Types, Thinking over Feeling Types, Judging over Perception Types had an increase of activeness of the parasympathetic nervous system. Therefore, meditation has a positive physical and psychological relaxing effect. Conclusions: A complex meditation program has a positive effect on overall meditation. Especially in the MBTI test, sensing was superior to intuition when people recognized objects. The Sensing, Thinking and Judging type was more advantageous than Intuition, Feeling and Perception, respectively. In the future, a well-designed control study is needed, to develop a suitable meditation for each personality type.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.6
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• pp.874-885
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• 2012

In the present study, the possibility of whether the pharmacological effects of Scutellariae Radix Aqueous Extracts(SR) were favorably changed by report that lipopolysaccharide(LPS)-induced rat acute lung injury was treated with Red-Koji(Monascus purpureus 12002) fermentation. Three different dosages of Red-Koji fermented SR extract(fSR), 125, 250 and 500 mg/kg were orally administered once a day for 28 days before LPS(Escherichia coli 0111:B4) treatments, and then 5 hours after LPS treatment(500 ${\mu}g$/head, intra trachea instillation), all rats were sacrificed. Changes in the body weights, lung weights, pulmonary transcapillary albumin transit, arterial gas parameters(pH, $PaO_2$ and $PaCO_2$) bronchoalveolar lavage fluid(BALF) protein, lactate dehydrogenase(LDH) and proinflammatory cytokine tumor necrosis factor-${\alpha}$(TNF-${\alpha}$), interleukin-$1{\beta}$(IL-$1{\beta}$) contents, total cell numbers, neutrophil and alveolar macrophage ratios, lung malondialdehyde(MDA), myeloperoxidase(MPO), proinflammatory cytokine TNF-${\alpha}$ and IL-$1{\beta}$ contents were observed with histopathology of the lung, changes on luminal surface of alveolus(LSA), thickness of alveolar septum, number of polymorphonuclear neutrophils(PMNs). As results of LPS-injection, dramatical increases in lung weights, pulmonary transcapillary albumin transit increases in $PaCO_2$, decreases in pH of arterial blood and $PaO_2$, increases of BALF protein, LDH, TNF-${\alpha}$ and IL-$1{\beta}$ contents, total cells, neutrophil and alveolar macrophage ratios, lung MDA, MPO, TNF-${\alpha}$ and IL-$1{\beta}$ contents increases were detected with decreases in LSA and increases of alveolar septum and PMNs numbers, respectively as compared with intact control. Especially fSR 125 mg/kg showed quite similar favorable effects on the LPS-induced acute lung injuries as compared with 60 mg/kg of ${\alpha}$-lipoic acid and 250 mg/kg of SR. The results suggest that over 125 mg/kg of fSR extracts showed favorable effects on the LPS-induced acute lung injury mediated by their antioxidant and anti-inflammatory effects. Moreover, increases of the pharmacological effects of SR on LPS-induced acute lung injury were observed by Red-Koji fermentation in this study, at least 2-fold higher.

• Toxicological Research
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• v.22 no.1
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• pp.61-67
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• 2006

Changes in hematology and serum biochemistry after treatment of recombinant human erythropoietin (rHuEPO, HM10760) were screened in 4 male cynomolgus monkeys (Macaca fascicularis). Four monkeys, composed of a treatment group of HM10760 and a positive control group of $Aranesp^(R}$, were subcutaneously administered at same dose of $100{\mu}g/kg$. Both groups did not show any change in body weights and food consumption for 4 weeks compared with those of pretreatment. Both groups did not show any change in total leukocyte count (WBC) and platelet count, while both groups showed increased platelet distribution width (PDW) percentage in HM10760 group during a period from day 5 to day 59 and in $Aranesp^(R}$ group during a period from day 9 to day 26. Both groups showed increases in red blood cells (RBC), hemoglobin (HGB), and hematocrit (HCT) approximately 10 days after treatment compared with those of pretreatment (day 0). The increased levels of RBC, HGB, and HCT were much higher in HM10760 than in $Aranesp^(R}$ by the increases of $3.2%{\sim}12.5%$ for RBC, $3.8%{\sim}17.1%$ for HCT, and $1.85%{\sim}11%$ for HGB. Both groups showed increases in red cells distribution width (RDW) and reticulocyte (RET) compared with those of pretreatment, showing the highest peak from day 9. The increased level of RET lasted up to day 14 in $Aranesp^(R}$ group, while it lasted up to day 23 in HM10760 group. The increased level of RDW lasted up to day 59, it was much higher in HM10760 by the increase of $10.1%{\sim}17.6%$ than in $Aranesp^(R}$ group. In serum biochemistry, both groups showed a decrease in chloride level compared with those of pretreatment. These findings indicated that HM10760 increased RBC, HGB, HCT, RDW, and RET compared with those of pretreatment, and the increased levels were much higher in HM10760 than in $Aranesp^(R}$.

• Korean Journal of Veterinary Research
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• v.55 no.2
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• pp.133-139
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• 2015

The increasing uses of zinc oxide nanoparticles (nZnO) in industrial and personal care products raise possible danger of using nZnO in human. To determine whether ZnO induces size-dependent anomalies during embryonic organogenesis, mouse embryos on embryonic day 8.5 were cultured for 2 days under 50, 100, and $150{\mu}g$ of nZnO (< 100 nm) or micro-sized ZnO (mZnO; $80{\pm}25{\mu}m$), after which the morphological changes, cumulative quantity of Zn particles, and expressions of antioxidant and apoptotic genes were investigated. Although embryos exposed to $50{\mu}g$ of ZnO exhibited no defects on organogenesis, embryos exposed to over $100{\mu}g$ of ZnO showed increasing anomalies. Embryos treated with $150{\mu}g$ of nZnO revealed significant changes in Zn absorption level and morphological parameters including yolk sac diameter, head length, flexion, hindbrain, forebrain, branchial bars, maxillary process, mandibular process, forelimb, and total score compared to the same dose of mZnO-treated embryos. Furthermore, CuZn-superoxide dismutase, cytoplasmic glutathione peroxidase (GPx) and phospholipid hydroperoxidase GPx mRNA levels were significantly decreased, but caspase-3 mRNA level was greatly increased in nZnO-treated embryos as compared to normal control embryos. These findings indicate that nZnO has severer teratogenic effects than mZnO in developing embryos.

• Journal of the Korean Association of Geographic Information Studies
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• v.5 no.4
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• pp.86-92
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• 2002

The feasibility of counting number of small vessels and position in Korean waters using the panchromatic imageries derived from the IRS-1C was tested. The parameters for interpretation of satellite's imageries of small vessels were location(position), size, shape, shadow, tone, texture and pattern, height and depth, situation and association with other vessels. The position of small vessels in the sea without GCP(ground control point) was considered to be inclusive in the satellite imagery with 35 km semi-diameter, denoting rough geographical position of the vessel. The size of vessel was measured by length from stem to stern of the vessel, distinguished by following wave on the surface water. Offshore fishing vessels were separated from merchant ships by their length smaller than 100 m. The shape of vessels on panchromatic imagery of IRS-1C appeared just streamline. In case of clouds which were similar to the shape of small vessels, we were able to distinguish between vessel and cloud by shadow of cloud in the water surface. The tone of sea surface was dark black while small vessel appeared bright white. Small vessel was distinguished from the rough texture of the sea surface and the regular pattern of the waves with white capes when weather was not so good. The situation of the fishing activity was estimated by information of fishing method related to the fishing boat such as the pair trawl in the Yellow Sea.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.4
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• pp.600-607
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• 2013

This study was performed to investigate the repeated-dose toxicity of Leuconostoc citreum GR1 (Leuc. citreum GR1), a lactic acid bacterium isolated from kimchi, in male and female rats. Sprague-Dawley male and female rats were divided into four group (ten animals in each group) and Leuc. citreum GR1 was administered daily by gavage to rats at dosage levels of 0, 500, 1,000, or 2,000 mg/kg/day for four weeks. There were no bacterial-related deaths or abnormal clinical signs in either gender of rats during the observation period. Furthermore, no differences were found between the control and treatment groups in terms of body weight, food intake, and water consumption. Hematological parameters, serum biochemical analysis, and histopathological examination also showed insignificant dose-dependent alterations. There were also no alterations in organ weights upon administration of Leuc. citreum GR1 alone. These results suggest the oral application of Leuc. citreum GR1, up to a dosage level of 2,000 mg/kg, causes no adverse effects in both male and female rats.