• 제목/요약/키워드: contamination prevention

검색결과 200건 처리시간 0.024초

A Survey on Microbial Contamination of Currently-Sold Drugs (I) -Bacterial contamination of marketed liquid- (시장의약품(市販醫藥品)의 미생물(微生物) 오염도(汚染度) 조사(調査) (제1보)(第1報) -시판내복액제(市販內服液劑)의 세균오염도(細菌汚染度)-)

  • Park, Young-Ju;Kim, Young-Il
    • Journal of Pharmaceutical Investigation
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    • 제3권4호
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    • pp.5-15
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    • 1973
  • An investigation was carried out on a basis of the bacteriological examination with a view to detecting the degree of bacterial contamination for the 77 samples collected from the locally-sold liquid specialties. It's test period was 50 days from July 10 to August 30, 1971. Specially, the survey has put emphasis on the population of general bacteria and the identification of coli-form group, staphylococcus species, streptococcus species, bacillus species, fungi, and yeast species from liquid samples. The results obtained are summarized as follows; (1) For the 77 samples tested, the contamination of general bacteria was found out as minimun 0, i,e., maximum, $12{\times}10^4$ and the total average $45{\times}10^2$ per milliliter. (2) Although streptococcus species could not be detected with the samples, the contamination of the coli-form and staphylococcus species means the strong suggestion of the possibility of pathogenic bacterial contamination. (3) Specially, the products which stay in the neutral pH range and use suspending agents need to care for the microbial contamination in the manufacturing crocess. (4) It is thought necessary to perform the microbiological quality control in the liquid preparations only at least. (5) As the microbial contamination degree in the liquid decreases according to the elapse of time, the microbiological quality control will have to be carried out immediately after the completion of the manufacturing process in order to know the accurate degree. (6) The author thinks that the main reason of the microbial contamination in the liquid is the contamination during the manufacturing process. (7) For the purpose of prevention of the microbial contamination in liquid, therefore, it is more important to make efforts for the rationalization of manufacturing process, the improvement of equipment and environment, the specific training of workers for hygienic knowledges, etc. rather than the use of preservatives for the preparations.

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The study about the method for supervising sea contamination in Korean EEZ (한국 EEZ내 해양오염방지 방안에 관한 연구)

  • 양성모;진종관
    • Journal of Korea Port Economic Association
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    • 제19권1호
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    • pp.113-138
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    • 2003
  • With it being inevitable to change the method of supervising as it is reorganized to EEZ coming out of the old concept of contamination in Korean area of the sea, it costs a lot to have good enough systems of total control for sea contamination and prevention of contamination as well as the effective marine superintendence because the governing bodies such as Ministry of Maritime Affairs and Fisheries, National Maritime Police Agency, and Authorities of Guiding Ships for Fishery, have their own source of laws and different ways to execute. In order to change such a wrong method of marine superintendence, it is necessary to conduct the merger and abolition of similar authorities with similar functions into authorities which are light but can be expected to play a major role, and to open the high-costing low-efficient organizations to make them remodel to be reborn as economical bodies. In addition to that, the maritime authorities, which are falling to incapable organizations not being able to work out any complicated tasks, have to be reborn as preventing bodies which take care of security and public peace and cut off a pollution source from sea and land.

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A Study on the Space Planing for Restaurant Kitchens to Improve Hygiene (식당 주방의 위생 향상을 위한 공간계획에 관한 연구)

  • Lee, Jong-Ran
    • Journal of The Korean Digital Architecture Interior Association
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    • 제11권1호
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    • pp.5-13
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    • 2011
  • This research proposed the space planing methode and diagrams of restaurant kitchens to improve hygiene by analyzing the related contents collected from books and researches in interior design and HACCP (Hazard Analysis and Critical Control Point). HACCP is an effective and scientific hygiene system for food safety in order to prevent cross-contamination from food hazards. Based on the analyses, improvement of food production environments like restaurant kitchens is necessary for food hygiene. The space planing methode of restaurant kitchens to improve hygiene are followings: The circulation planing is that the direction of movement of the food, workers, waste, and dishes should be fractionated and managed for cross-contamination prevention. The space separation planing is that the spaces in the kitchen should be classified and divided into contaminated area and non-contaminated and clean area depending on the degree of cleanliness. The zoning is space arrangement with feed-back process to check the possible points of cross-contamination and correct space arrangement until the possibility of cross-contamination disappear in kitchen. However, if cross-contamination is unavoidable in some points in restaurant kitchens, hygiene facilities such as washing rooms, pass rooms, and double doors with air-shower should be located in order to remove contamination.

Policy Suggestions for Soil Contamination Prevention and Management of Inactive or Abandoned Metal Mines (휴.폐금속광산지역의 토양오염관리정책의 평가)

  • Park Yong-Ha;Seo Kyung-Won
    • Journal of Soil and Groundwater Environment
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    • 제11권3호
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    • pp.1-11
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    • 2006
  • Attempts were made to analyze the national policy of soil contamination prevention and management of inactive or abandoned metal (IAM) mines in Korea. This approach focused on legal systems and legislation, remediation technology development, and the arrangement or distribution of budgets pertaining to national policy since the mid 1990's. Prevention of Mining Damage and Recovery Act enacted. Defines the roles, responsibility and budget of the government when recovering mine damages. However, in 2005 there still remains to improve the national policy of soil contamination prevention and management of IAM mines. Analysis of national and industrialized foreign countries including the United States, the United Kingdom, and the Netherlands suggest the following improvements: i) arranging distinct regulations between strict and non-strict liability criteria for potentially responsible parties; limiting innocent and non-strict liability depending on the period of incurred mining activity, ii) enhancing participation of local communities by enforcing law and legislation, iii) establishing a national database system of (potentially) IAM contaminated sites based on the Website-Geographic Information System, iv) carrying out site-specific risk assessments and remediation of IAM contaminated sites, v) preparation and distribution of clean-up fund at mine sites adequately, and vi) technology development for the cleaning of IAM contaminated sites; awarding positive incentives of a legal nature for participants applying newly developed technology in IAM mines.

Blood culture contamination in hospitalized pediatric patients: a single institution experience

  • Min, Hyewon;Park, Cheong Soo;Kim, Dong Soo;Kim, Ki Hwan
    • Clinical and Experimental Pediatrics
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    • 제57권4호
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    • pp.178-185
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    • 2014
  • Purpose: Blood culture is the most important tool for detecting bacteremia in children with fever. However, blood culture contamination rates range from 0.6% to 6.0% in adults; rates for young children have been considered higher than these, although data are limited, especially in Korea. This study determined the contamination rate and risk factors in pediatric patients visiting the emergency room (ER) or being admitted to the ward. Methods: We conducted a retrospective chart review of blood cultures obtained from children who visited Yonsei Severance Hospital, Korea between 2006 and 2010. Positive blood cultures were labeled as true bacteremia or contamination according to Centers for Disease Control and Prevention/National Healthcare Safety Network definitions for laboratory-confirmed bloodstream infection, after exclusion of cultures drawn from preexisting central lines only. Results: Among 40,542 blood cultures, 610 were positive, of which 479 were contaminations and 131 were true bacteremia (overall contamination rate, 1.18%). The contamination rate in the ER was significantly higher than in the ward (1.32% vs. 0.66%, P<0.001). The rate was higher in younger children (2.07%, 0.94%, and 0.61% in children aged <1 year, 1-6 years, and >6 years, respectively). Conclusion: Overall, contamination rates were higher in younger children than in older children, given the difficulty of performing blood sampling in younger children. The contamination rates from the ER were higher than those from the ward, not accounted for only by overcrowding and lack of experience among personnel collecting samples. Further study to investigate other factors affecting contamination should be required.

Modelling for Dilution Ventilation of Indoor Contamination Materials (실내 오염물질의 희석환기에관한 모델링)

  • Sim, Seong-Hun;Jo, Sang-Jun;Kim, Gwang-Yeong
    • 한국기계연구소 소보
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    • 통권19호
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    • pp.31-42
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    • 1989
  • To investigate design factors of dilution ventilation system, numerical analysis of air contamination flow and concentration distribution have been made, by using the low Reynolds number turbulent model. And flow visualization and measurement of particle concentration for that model also have been made. By comparing of these results we have secured the essential data for the adequate counterplan of dilution ventilation system. The results of this study are as follows: 1) Inlet should be located near the wall for the prevention of the formation of the recircula¬tion zone. 2) In case of natural exhaust, air contamination flow is driven to the far outlet from the inlet. 3) It is favorable for dilution to make turbuence as much as possible.

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A Study of the Mask and Hand Contamination in Dental Clinic (치과에서의 마스크 및 손의 미생물 오염정도 비교)

  • Pyo, Eunji;Lee, Kyunghee
    • Journal of The Korean Society of Integrative Medicine
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    • 제7권3호
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    • pp.85-94
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    • 2019
  • Purpose: The purpose of this study was to observe the degree of mask contamination in dental hygienist for general and oral bacteria and to identify areas of mask contamination after treatment. Methods: Masks were collected with every fifty dental hygienists who currently working in the department of preventive dentistry, prosthodontics, and orthodontics in Busan. The mask bacteria were collected in specific upper and side parts of the mask. Hand germs were collected using sterile cotton swabs, and then placed in a sterile conical tube. These were transferred to the laboratory. Hand germs and mask bacteria were incubated with nutrient broth (NB) and brain heart infusion broth (BHI) for 24 hrs and each cultured with NB and BHI plate at $37^{\circ}C$ for 48 hrs. Collected data were analyzed using the SPSS Window 20. Results: The number of bacteria was observed in the order of the department of preventive dentistry ($10.1{\times}10^5CFU/ml$), prosthodontics ($14.7{\times}10^5CFU/ml$), and orthodontics ($23.3{\times}10^5CFU/ml$) in the hand. In general bacteria, the difference of contamination was seen by the parts of the mask, but there was no significant difference. However, the oral bacteria were observed highly contaminated upper part of the mask in preventive dentistry. The mask contamination according to the medical departments was observed. Especially, the contamination of mask in preventive dentistry was significantly higher than other departments in oral bacteria. Conclusion: This study suggested that correct mask replacement and recognition of contamination areas can contribute to the prevention of infectious disease. and it would be necessary to increase hand hygiene performance to prevent cross-infection with masks. Also, this study may give an idea for making guidelines for mask management and supporting to establish clear criteria for the education program of personal protective equipment.

Fumonisin B1 Contamination of Cereals and Risk of Esophageal Cancer in a High Risk Area in Northeastern Iran

  • Alizadeh, Ali Mohammad;Roshandel, Gholamreza;Roudbarmohammadi, Shahla;Roudbary, Maryam;Sohanaki, Hamid;Ghiasian, Seyed Amir;Taherkhani, Amir;Semnani, Shahryar;Aghasi, Maryam
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권6호
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    • pp.2625-2628
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    • 2012
  • Introduction: Fumonisin B1 (FB1) is a toxic and carcinogenic mycotoxin produced in cereals due to fungal infection. This study was conducted to determine FB1 contamination of rice and corn samples and its relationship with the rate of esophageal cancer (EC) in a high risk area in northeastern Iran. Methods: In total, 66 rice and 66 corn samples were collected from 22 geographical subdivisions of Golestan province of Iran. The levels of FB1 were measured for each subdivision by thin layer and high pressure liquid chromatographies. The mean level of FB1 and the proportions of FB1 contaminated samples were compared between low and high EC-risk areas of the province. Results: The mean of FB1 levels in corn and rice samples were 223.64 and 21.59 ${\mu}g/g$, respectively. FB1 contamination was found in 50% and 40.9% of corn and rice samples, respectively. FB1 level was significantly higher in rice samples obtained from high EC-risk area (43.8 ${\mu}g/g$) than those obtained from low risk area (8.93 ${\mu}g/g$) (p-value=0.01). The proportion of FB1 contaminated rice samples was also significantly greater in high (75%) than low (21.4%) EC-risk areas (p-value=0.02). Conclusion: We found high levels of FB1 contamination in corn and rice samples from Golestan province of Iran, with a significant positive relationship between FB1 contamination in rice and the risk of EC. Therefore, fumonisin contamination in commonly used staple foods, especially rice, may be considered as a potential risk factor for EC in this high risk region.

Rehabilitation Method and Case of Closed Waste Landfill (사용종료매립지 정비방법 및 정비사례 분석)

  • 정하익
    • Proceedings of the Korean Geotechical Society Conference
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    • 한국지반공학회 2001년도 지반환경 및 준설매립에관한 학술세미나
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    • pp.85-95
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    • 2001
  • There has been a steady increase in closed waste landfill. Sanitary and contamination prevention systems such as liner system, leachate treatment, gas treatment system were not installed in unregulated waste landfill. This study was carried out to introduce the rehabilitation method and case of unregulated closed landfill.

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