• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제34권6호
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• pp.602-610
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• 2008

Purpose Acrylamide is present in significant quantities in a wide range of commonly consumed human foods. Carcinogenic risk of acrylamide through the consumption of food is a great public concern and in controversy, but it is not properly addressed due to the lack of evidence in humans. While a plenty of data is available on the carcinogenicity in animal models, the studies in humans are limited. Thus, the present study attempted to examine the carcinogenic potentials of acrylamide on the human epithelial cell, which is the target cell origin of the most cancers. Material and method & Result 1. Acrylamide was not cytotoxic up to $100{\mu}M$ as measured by MTT and LDH assays, indicating a relatively low toxicity of this substance in human epithelial cells. 2. The parameters of neoplastic cellular transformation such as cell saturation density, soft-agar colony formation and cell aggregation were analyzed to examine the carcinogenic potential of acrylamide. 3. The neoplastic transformation was further increased with the co-treatment of TPA 4. Antioxidants blocked the generation of Reactive Oxygen Species(ROS) and the GSH depleting agent dramatically increased the ROS production. 5. mRNA levels of fibronectin following acrylamide exposure was increased in a dose-dependent manner, indicating a possible biomarker of acrylamide-induced cellular transformation. Conclusion The present study will provide a valuable basis to compare the interspecies differences in response to carcinogenic potentials of acrylamide. The data on the interspecies differences are essential element in human risk assessment. Thus, our results obtained from the human epithelial cells will contribute to improving the risk assessment of human neoplasm including oral cancer.

• 디지털융복합연구
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• 제11권12호
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• pp.735-745
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• 2013

관광산업은 여가시간의 증가와 함께 질적으로나 양적으로 큰 성장을 보이고 있다. 지역을 대표하는 관광콘텐츠 개발이 활발하게 이루어짐에 따라 관광콘텐츠는 지역을 방문하는 관광객에게 단순한 여행서비스를 제공하는 것을 넘어 최고의 경험을 제공하는 단계로 발전을 했다. 하지만 이러한 관광콘텐츠는 지역성의 차이 이외에는 그 구성이나 속성에 크게 차별성이 없는 명목상의 관광콘텐츠도 적지 않다. 관광콘텐츠가 개인에게 감동을 주고 이것이 소비로 이어지기 위해서는 개인에 대한 이해, 개인의 경험에 대한 이해가 필요하기 때문에 서비스 경제사회를 넘어 체험경제사회로 접어든 현재에 '경험'은 관광콘텐츠를 상품으로 기획, 개발하는 하나의 기준이 될 수 있다. 이러한 맥락에서 이 글에서 다루는 체험경제이론의 체험4요소와 몰입론의 Challenge-skill 모델은 양질의 관광콘텐츠를 기획/개발하는 단계에서 관광객의 경험을 구체화시켜주는 틀을 제공해줄 수 있다. 이 글은 결과적으로 콘텐츠를 일종의 체험으로 보았을 때, 체험4요소를 통해 최대의 즐거움을 제공할 수 있는 4가지 요소를 제안하였고, 몰입론을 통해 콘텐츠의 수준과 관광객의 이해라는 측면에서 제공되어야 하는 균형 잡힌 콘텐츠에 대해 제안하였다.

• 디지털콘텐츠학회 논문지
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• 제19권6호
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• pp.1043-1050
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• 2018

식문화 편의경제 시대의 본격화로 인해 간편하고 편리하게 식사를 해결하려는 소비 트렌드가 확산됨에 따라 각 식품업체에서는 더 나은 서비스를 제공하기 위해 다방면으로 노력하고 있다. 이러한 변화와 함께 주문방법에 있어서도 다양한 방식을 채택하여 신속하고 간편한 주문이 가능해졌다. 특히, 계산을 위한 대기열의 단축, 인건비의 절약, 업무프로세스의 원활함 등 여러 장점을 지닌 키오스크 주문 시스템의 도입은 최근 적극적으로 확산되고 있다. 키오스크 시스템이 주문뿐만 아니라 체계적인 콘텐츠를 제공하고 타 기업과 차별화 된 아이덴티티를 고려한 인터페이스 디자인을 제공한다면 브랜드 이미지 향상과 더불어 고객서비스 전략으로 활용 가능할 것이다. 이에 본 연구에서는 패스트푸드점 내 키오스크의 구조 및 콘텐츠, 그리고 GUI 디자인에 관해 분석하고 사용자 설문조사를 통해 키오스크의 사용 실태 및 디자인 선호도를 조사함으로써 사용자에게 보다 편리한 사용성을 제공하고 만족도를 높일 수 있는 효과적인 상호작용을 위한 키오스크 GUI 디자인 방안에 관해 연구한다.

• 디지털콘텐츠학회 논문지
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• 제19권6호
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• pp.1033-1041
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• 2018

본 연구는 모바일 게임에서 두드러지게 나타나고 있는 게임 패턴에 대한 내용을 담고 있다. 본 연구에서 사용하고 있는 '패턴'이라는 용어는 곽이삭(2016)이 <게임의 사용자 경험에 대한 연구: 게임 공간의 패턴과 속성을 중심으로>에서 사용한 개념을 계승한다. 앞선 연구와의 차이점은 '패턴'은 게이머의 경험 패턴을 '게임 공간'에서 '모바일 게임 시장'으로 범위를 확대하여 사용한다는 점이다. 모바일 게임 시장은 급속도로 성장하고 있으나, 모바일 게임을 개발하는 측면에 있어서는 개발 시간의 축소, 장르 파괴 등으로 인해 게임이 획일화되어가는 경향을 보인다. 때문에 연구자는 이러한 상황을 인지하여 현재의 모바일 게임 시장에서 나타나는 경험의 패턴을 '익숙한 플레이의 반복', '가치 있는 게임 행위', '시간의 가치와 소비', '취향과 선택'의 패턴으로 요약하여 설명하고자 하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권11호
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• pp.4429-4436
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• 2014

Background: Although the nutritional may exert effect on the breast cancer risk, it is not clear whether the role diet is the same in sedentary and physically active women. The aim of this study was to evaluate the association between fruit, vegetable and carbohydrate intake and the risk of breast cancer among Polish women considering their physical activity level. Materials and Methods: A case-control study was conducted that included 858 women with histological confirmed breast cancer and 1,085 controls, free of any cancer diagnosis, aged 28-78 years. The study was based on a self-administered questionnaire to ascertain physical activity, dietary intake, sociodemographic characteristics, reproductive factors, family history of breast cancer, current weight and high, and other lifestyle factors. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated in unconditional logistic regression analyses including a broad range of potential confounders. Results: With comparison of the highest vs lowest quartile of intake, strong significant associations were observed for total vegetables (OR=0.37, 95%CI=0.20-0.69 P for trend <0.01 and OR=0.53, 95%CI=0.29-0.96, P for trend <0.02), and total fruits (OR=0.47, 95%CI=0.25-0.87, P for trend <0.05 and OR=0.47, 95%CI=0.24-0.90, P for trend <0.02) among women characterized by the lowest and the highest quartile of physical activity. No associations were observed for total carbohydrate intake. Additional analysis showed a positive association for sweets and desert intake among women in the lowest quartile of physical activity (OR=3.49, 95%CI=1.67-7.30, P for trend <0.009) for extreme quartiles of intake comparing to the referent group. Conclusions: The results suggest that a higher consumption of vegetable and fruit may be associated with a decreased risk of breast cancer, especially among women who were low or most physically active throughout their lifetimes. These findings do not support an association between diet high in carbohydrate and breast cancer. However, a higher intake of sweets and deserts may by associated with an increased risk of breast cancer among women who were less physically active.

• 한국의류산업학회지
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• 제19권6호
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• pp.671-680
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• 2017

Contemporary people can form a broad social sympathy on cultural products based on the present Korean image. K-pop is good material to use to share korean culture, and fans who are enthusiastic here are increasingly demanding cultural products. The visual materials of Bangtan Boys are collected from their album covers, and a concept book, and divided into specific and symbolic images. Based on this motif, three specific images: 'bulletproof vest', 'army house + superhero extract image', and 'Wings symbol', six designs were proposed. In addition, six motifs from the music videos for recent popular songs, 'Spring Day', 'Blood, Sweat and Tears' and 'Burning Up' were selected as symbolic images. Each selected image is divided into a normal line and a special line. The former is a relatively small, stable, and popular style, and the latter is a large, original, and bold style. By drawing and transforming extracted images and motifs using Adobe Illustrator CS6 and Adobe Photoshop CS6 program, a full-width umbrella design was developed. The messages that the Bangtan Boys wants to convey through their music are put into cultural products that contemporaries can sympathize with. By developing umbrellas, a variety of items and design goods can become desirable points of consumption as high-value products by domestic and foreign fandom. If designs that incorporate various elements of future K-pop contents as well as other Korean Wave contents are developed, it will be possible to develop original design products that will form global understanding.

• Journal of Nutrition and Health
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• 제38권2호
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• pp.125-143
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• 2005

The purposes of this study were to investigate the characteristics of lifestyle and dietary habits of the colorectal cancer patients in Daegu and Kyungpook areas and to collect the data useful for nutrition education for the prevention of colorectal cancer in this community. The case subjects of the study were 123 patients diagnosed recently as colorectal cancer at Kyungpook National University Hospital. The control subjects were 182 persons who did not have any gastrointestinal diseases, including the patients from the department of orthopedic surgery and healthy volunteers. The survey covering general characteristics, life style, dietary habits, eating behaviors, and food intake frequency was administered by individual interviews using questionnaires. The results of the study suggest that high BMI, daily life stress, pessimistic personality, lack of physical activities, and familial cancer history might be the possible risk factors for the incidence of colorectal cancer. Dietary factors suspected as risk factors for colorectal cancer in the present study included strong preferences to meats, salty and fatty taste foods, low intake of water, alcohol drinking, smoking, coffee intake and irregular eating habits. A high consumption of seaweeds, green-yellow vegetables, light-colored vegetables, and green tea was suggested as a preventive factor for colorectal cancer. It is recommended to conduct more extensive and systematic surveys in the near future to reconfirm the risk factors of colorectal cancer in consideration of the characteristic food culture in this community. The results of the present study may be applied to nutritional education for the prevention of colorectal cancer for the local residents. (Korean J Nutrition 38(2): 125～143, 2005)

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제27권2호
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• pp.135-141
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• 2001

Recently, the consumption of soy products has been associated with low rates of hormone-dependent and hormone-independent cancers. Asians, who consume $20{\sim}50times$ more soy per capita than Americans, have lower incidence and death rates from breast and prostate cancer. Because soy contains the isoflavones genistein and daidzein (present as their glycosidic conjugates) at mg/g concentrations, it has been suggested that isoflavones might be acting as natural chemopreventive agents. During the 1980s several groups of investigators carried out experiments to test the effectiveness of soy in the diet in animal models of cancer. These studies reported a protective effect of soy; none showed that soy increased cancer risk. Genistein was shown to inhibit the growth of a wide variety of tumor cell types in culture. The purpose of this study was to evaluate the effects of genistein on the carcinogenesis induced by topical application of 0.5% 9, 10-dimethyl 1,2-benzanthracene (DMBA) on the hamster buccal pouch. 48 syrian hamsters were employed in this study, divided into experimental group and control. 24 animals (DMBA topical application group) had the right buccal pouch painted 3times weekly with 0.5% DMBA in mineral oil, 24 animals (genistein group) were supplied with 0.1mg genistein with DMBA topical application. 3 animals in the experimental group and control were sacrificed at serially each other week after experiments. Their buccal pouches were removed and routinely processed for microscopic examination. The results were as follows: 1. In DMBA topical application and genistein group, they showed carcinogenesis as time goes by experimental stage. 2. Genistein group was retarded in carcinogenesis related to the acanthosis, hyperkeratosis, epithelial dysplasia. 3. p53 immunohistochemical study showed that the p53 protein of genistein group was less expressed than that of the control group. Thus, it seems that genistein has chemopreventive effect on the carcinogenesis in the oral cavity, but further study is required to elucidate the anticancer mechanism of genistein.

• Asian-Australasian Journal of Animal Sciences
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• 제31권7호
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• pp.1017-1035
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• 2018

The European Union (EU) is the world's third largest producer of beef. This contributes to the economy, rural development, social life, culture and gastronomy of Europe. The diversity of breeds, animal types (cows, bulls, steers, heifers) and farming systems (intensive, extensive on permanent or temporary pastures, mixed, breeders, feeders, etc) is a strength, and a weakness as the industry is often fragmented and poorly connected. There are also societal concerns regarding animal welfare and environmental issues, despite some positive environmental impacts of farming systems. The EU is amongst the most efficient for beef production as demonstrated by a relative low production of greenhouse gases. Due to regional differences in terms of climate, pasture availability, livestock practices and farms characteristics, productivity and incomes of beef producers vary widely across regions, being among the lowest of the agricultural systems. The beef industry is facing unprecedented challenges related to animal welfare, environmental impact, origin, authenticity, nutritional benefits and eating quality of beef. These may affect the whole industry, especially its farmers. It is therefore essential to bring the beef industry together to spread best practice and better exploit research to maintain and develop an economically viable and sustainable beef industry. Meeting consumers' expectations may be achieved by a better prediction of beef palatability using a modelling approach, such as in Australia. There is a need for accurate information and dissemination on the benefits and issues of beef for human health and for environmental impact. A better objective description of goods and services derived from livestock farming is also required. Putting into practice "agroecology" and organic farming principles are other potential avenues for the future. Different future scenarios can be written depending on the major driving forces, notably meat consumption, climate change, environmental policies and future organization of the supply chain.

• 복식
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• 제64권4호
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• pp.176-187
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• 2014

Although DIY(Do-It-Yourself) clothes are not popular in Korea, they continually reflect emerging DIY trends. Previous studies have approached the technical aspect of DIY clothes or have considered them only as an aspect of consumption tendencies. The purpose of this study is to look into online communities to investigate distinctive elements, which form the DIY clothing culture. Participant observation of texts and pictures from the online community's postings about DIY was conducted and used for the analysis. Research results showed that personal and social factors motivated DIY clothes. Personal motivations are comprised of factors such as practical creativity and personal enjoyment. Practical creativity occurred when someone wished to express aesthetics and personality in DIY clothes; personal enjoyment refers to the pleasure and utility that one feels when one makes DIY clothes. The social motivations were comprised of factors such as a desire to show off and to expand social exchanges. The desire to show off involved wearing DIY clothes and then finding satisfaction from reactions of people who notice it. The "expansion of exchanges" was not only about sharing information about DIY clothes in an online community but also about distributing or giving real goods (materials or tools for DIY clothes and finished goods) as gifts. Furthermore, some "DIYers" made DIY clothes sustainable by pursuing economic feasibility as an additional motivational factor. When they had expertise and commercial traits, they established businesses in the form of independent creative firms, transforming themselves from productive consumers to producers.