• Genomics & Informatics
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• v.14 no.4
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• pp.196-204
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• 2016

Many researchers have found that one of the most important characteristics of the structure of linkage disequilibrium is that the human genome can be divided into non-overlapping block partitions in which only a small number of haplotypes are observed. The location and distribution of haplotype blocks can be seen as a population property influenced by population genetic events such as selection, mutation, recombination and population structure. In this study, we investigate the effects of the density of markers relative to the full set of all polymorphisms in the region on the results of haplotype partitioning for five popular haplotype block partition methods: three methods in Haploview (confidence interval, four gamete test, and solid spine), MIG++ implemented in PLINK 1.9 and S-MIG++. We used several experimental datasets obtained by sampling subsets of single nucleotide polymorphism (SNP) markers of chromosome 22 region in the 1000 Genomes Project data and also the HapMap phase 3 data to compare the results of haplotype block partitions by five methods. With decreasing sampling ratio down to 20% of the original SNP markers, the total number of haplotype blocks decreases and the length of haplotype blocks increases for all algorithms. When we examined the marker-independence of the haplotype block locations constructed from the datasets of different density, the results using below 50% of the entire SNP markers were very different from the results using the entire SNP markers. We conclude that the haplotype block construction results should be used and interpreted carefully depending on the selection of markers and the purpose of the study.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.6D
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• pp.673-678
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• 2012

Accurate demand estimating process in the construction of urban railway is very important, and precise validation is required. Existing model formula in the 4 phase model is limited in the estimation of the demand the administrative boundary-based zone system reflects no spatial railway demand characteristics around railway stations. The purpose of this study is improving the accuracy of urban rail demand estimation through segmentations of station influence areas and modal split characteristics within the areas. According to the case analysis, it is possible to set up the ststion influence area with a radius of 500m in the urban region and 1,000m in the suburban. And eastablishing proper segmentations of the ststion influence area shows more accurate results to the real demand of railway stations.

• Journal of Korean Society of Water and Wastewater
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• v.29 no.4
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• pp.511-517
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• 2015

Korea's modern waterworks began with construction of DDukdo water treatment plant in 1908 and has been growing rapidly along with the country's economic development. As a result, water supply rates have reached 98.5% based on 2013. Despite multilateral efforts for high-quality water supply, such as introduction of advanced water treatment process, expansion of waterworks infrastructure and so on, distrust for drinking tap water has been continuing and domestic consumption rate of tap water is in around 5% level and extremely poor comparing to advanced countries such as the United States(56%), Japan(52%), etc. Recently, the water management has been facing the new phase due to water environmental degradation caused by climate change, aging facilities, etc. Therefore, K-water has converted water management paradigm from the "clean and safe water" to the "healthy water" and been pushing the Smart Water City(SWC) Pilot Project in order to develop and spread new water supply models for consumers to believe and drink tap water through systematic water quality and quantity management combining ICT in the whole water supply process. The SWC pilot projects in Pa-ju city and Go-ryeong county were an opportunity to check the likelihood of the "smart water management" as the answer to future water management. It is needed to examine the necessity of smart water management introduction and nationwide SWC expansion in order to improve water welfare for people and resolve domestic & foreign water problems.

• The Korean Journal of Emergency Medical Services
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• v.7 no.1
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• pp.147-178
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• 2003

In terms of reinforcing the functions and services of rescue 119 and emergency corps, we must review the following considerations : Building up security system along with operational expansion, building up a system for emergency medical treatment, buliding up a comprehensive information management system for rescue and emergency, constructing a provincial safety museum and so forth. For the ways to better the works of rescue 119, we can review the following considerations : Improving the education for fire fighting trainging corps under Jeju Provicial Fire and disaster management department, providing rescue members with more opportunity for clinical practices, enhancing the morale of rescue members, installing a comprehensive briefing room for emergency rescue members, building up medical networks along with reasonable policies for information service, operating the consulting system for rescue 119 and so on. Provide little more superior quality high fire fighting service to jeju islander, and need long-term and elaborate research to correspond in rising fire fighting man-power demand newly and investment. Construction of well-matched disaster administration system is assignment that must hurry in international free city. That jejudo receives time factor about that is received for another thing area's number of persons or equipment when regional special quality large scale or disaster happens is that of course the support receives limitation immediately. Jeju fire fighting services is one story reform, specialization taking into account particular situation of jeju area to grow as sightseeing and center of culture intending international free city, should be upgraded. So, it may do big contribution naturally in jeju international free city phase that coincide jeju islander's social welfare promotion and safety desire.

• The KIPS Transactions:PartD
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• v.10D no.3
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• pp.547-558
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• 2003

From the viewpoint of that music melody has the similar features to time-series data, music melody is transformed to a time-series data with normalization and corrections and the similarity between melodies is defined as the Euclidean distance between the transformed time-series data. Then, based the similarity between melodies of a music object, melodies are clustered and the representative of each cluster is extracted as one of theme melodies for the music. To construct the theme melody index, a theme melody is represented as a point of the multidimensional metric space of M-tree. For retrieval of user's query melody, the query melody is also transformed into a time-series data by the same way of indexing phase. To retrieve the similar melodies to the query melody given by user from the theme melody index the range query search algorithm is used. By the implementation of the prototype system using the proposed theme melody index we show the effectiveness of the proposed methods.

• International Journal of Aeronautical and Space Sciences
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• v.17 no.4
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• pp.518-525
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• 2016

This paper presents the characteristics of non-fundamental multi-mode combustion instability and the effects of high-harmonic components on the Rayleigh criterion. Phenomenological observations of multi-harmonic-mode dynamic pressure waves regarding the intensity of harmonic components and the source of wave distortion have been explained by introducing examples of second- and third-order harmonics at various amplitudes. The amplitude and order of the harmonic components distorted the wave shapes, including the peak and the amplitude, of the dynamic pressure and heat release, and consequently the temporal Rayleigh index and its integrals. A cause-and-effect analysis was used to identify the root causes of the phase delay and the amplification of the Rayleigh index. From this analysis, the skewness of the dynamic pressure turned out to be a major source in determining whether multi-mode instability is driving or damping, as well as in optimizing the combustor design, such as the mixing length and the combustor length, to avoid unstable regions. The results can be used to minimize errors in predicting combustion instability in cases of high multi-mode combustion instability. In the future, the amount of research and the number of applications will increase because new fuels, such as fast-burning syngases, are prone to generating multi-mode instabilities.

• Journal of Advanced Marine Engineering and Technology
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• v.39 no.3
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• pp.201-205
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• 2015

This paper describes thermal flow characteristic in various pipelines: straight pipeline and curved pipeline. In the Arctic and ocean area, pipelines are exposed to a extremely low temperature ($0{\sim}-40^{\circ}C$). In this situation, three-dimensional flow analysis should be analyzed to investigate thermal effects such as pressure drop, temperature change, velocity deficit and distribution change of liquid droplet of internal fluid. Also, due to freezing of water droplet, impingement erosion is expected in the curved pipeline. The stability of the pipelines can be influenced by impingement erosion. In this paper, multi-phase and multi-species analysis was introduced to analyze the flow characteristics and impingement erosion of Arctic and ocean pipelines.

• Archives of design research
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• v.16 no.2
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• pp.5-14
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• 2003

Magazines in this 21st century which is most influenced by digital medium are in the middle position widely between traditional one; broadcastings & newspapers and new one; the mediums based on internet. Although most of the people said magazines were disappeared by growth of the digital technology, contrary to their expectations, magazines have more fixed position now by professionalizing itselves with more diverse themes. However, digital media such as Internet became a part of every day life that cannot be ignored, and digitalization of magazines was not an option but an indispensable stipulation. Especially, web version development of existing magazines is becomes an urgent issues. Therefore, the study of type of expression that can be used for existing publishers to keep their identity on digital medium is a necessary result. As the study which it sees regarding the notion and an intergral part of the Magazine Identity it leads, it materialize the construction phase of the Magazine Identity. With this categorization which will reach domestic, it compares and analyzes an outside instance, presently it constitute the expression type of a magazine that is published.

• Journal of Electrical Engineering and Technology
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• v.10 no.5
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• pp.1921-1929
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• 2015

The smart substation is the heart of a transmission system, which is particularly emphasized as the most significant composition of smart grids in China. In order to assess the functionality performance of substation technologies, this paper presents methods used to identify the most promising solutions for smart substation design and to evaluate the technical levels of available technologies. The multi-index optimization model is presented to address the issue of smart substation planning. A mathematical model of the planning decision problem is established with multiple objectives consisting of economic, reliability, and green key indices, and many kinds of concerns including physical and environmentally friendly operations are formulated as a set of constraints. With respect to the assessment of the technical level regarding integration of advanced technologies into a substation, a modified grey whitenization weight function is adopted to structure a novel grey clustering method. The proposed grey clustering approach is used to overcome the difficulty of insufficient quantitative assessment capacity for traditional methods. The evaluation of technical effects provides the classification definition for the development phase and the maturity level of the smart substation. The effectiveness of the proposed approaches in planning decision-making and evaluation of construction efforts is demonstrated with case studies involving the actual smart substation projects of Wenchongkou substation in China Southern Power Grid (CSG) and Mengzi substation in State Grid Corporation of China (SGCC).

• KIEAE Journal
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• v.16 no.1
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• pp.121-130
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• 2016

Purpose: This paper is an attempt to explicate the principle of space and form-making in Le Corbusier's architecture from the viewpoint of integrating and relating architecture with the natural landscape. It shows thereby how the geometrical element of architecture and the non-geometrical element of the nature coexist in terms of form. It also explains how space is deployed for the construction of cognitive system between natural landscape and architectural scenery in terms of space, hoping to make a contribution to design method of contemporary house as an elementary datum. Method: Three issues are studied, focusing on the designs around nineteenth thirties in the earliest phase of Le Corbusier: How architectural form and nature is related, how natural greens is introduced into urbanism, and how natural landscape is introduced to house design. 1) it is studied how the relation between the nature and the formal elements of purism in Le Corbusier's architecture is formed. 2) it is studied how the relation between the nature and architecture proposed in Le Corbusier's urbanism is formed. 3) Le Corbusier's "four compositions" is analyzed in terms of relation-formation between architectural space and the nature. 4) it is studied how the natural landscape is introduced to Le Corbusier's house-design in the form of architectural promenade. Result: It has been found out that the natural landscape in Le Corbusier's architecture is not just a simple background, but a necessary element for the consummation of form and space in his architecture, and that architectural inspiration is maximized with coexistence with nature.