• Journal of Sasang Constitutional Medicine
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• v.16 no.1
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• pp.12-19
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• 2004

Puporse This study is intended to distinct of Taeumin chungsimyeonjatang on the Shinchukpan Dongyi Suse Bowon through compare with early books' prescription by studying use of Sanyak and Yeonjayuk. Method This study is reserch to use of Sanyak and Yeonjayuk in early books, Dongyi Suse Bowon-Sasang-chobonkyeon, Gapobon Dongyi Suse Bowon, Shinchukpan Dongyi Suse Bowon and Dongyibogam, Taepyungheymin-hwajegukbang in sequence of date. with this, we study a base of virtue of Taeumin chungsimyeonjatang. Result and conclusion 1. Taeumin chungsimyeonjatang is a prescription of treatment Gonscratia and CVA. 2. Taeumin chungsimyeonjatang is base on Chungsimyeonjaum in Dongyibogam. 3. The chief virtue of Taeumin chungsimyeonjatang is accord with all prescription after 1894's Gapobon Dongyi Suse Bowon.

• Journal of Sasang Constitutional Medicine
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• v.23 no.4
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• pp.548-556
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• 2011

1. Objective To review the effectiveness affecting to acne patients by Yeoldahanso-tang(熱多寒少湯) and Hyangsayangyi-tang(香砂養胃湯) who were constitutionally typed as Taeeumin and Soeumin 2. Methods The patient's subjective and objective symptoms were observed. After treatment's we compared the photos before and after, and estimated by Korean Acne Grading System(KAGS-2) 3. Results After we treated two cases of acne patient with constitutional prescription, their symptoms and result of KAGS-2 improved 4. Conclusions This case study showed an effectiveness of using Sasang Constitutional prescription in Taeeumin and Soeumin to Acne.

• Journal of Sasang Constitutional Medicine
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• v.14 no.1
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• pp.10-25
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• 2002

1. Purpose This Study is intended to catch the expasion of theory of Sasang Constitutional Medicine through comparision DongyiSooseBowon Chopanbon with DongyiSooseBowon Chobonguen and DongyiSooseBowon Gabobon. 2. Method I compared the Soeumin's prescriptions and medications of DongyiSooseBowon Chopanbon with those of DongyiSooseBowon Chobonguen and DongyiSooseBowon Gabobon. 3. Result and conclusion 1. The Soeumin's meducations used in the prescriptions of chobonguen are 44 and those of Gabobon are 47, those of chopanbon are 46 2. Soeumin;s Medications of the same kind in Chobonguen's precriptions and Gabobon's and Chopanbon's are twenty-five;like Daejo(大棗), Jinpi(陳皮), Gamcho(甘草), etc. and these medications are the princople in soeumin's disease. 3. Soeumin's Prescriptions of the same name in Chobonguen's prescriptions and Gabobon's and Chopanbon's are two;Gwakhanggeunggisan(藿香精氣散) and Bogungikgitang(補中益氣湯). These two prescriptions are correspond to the prescriptions those were recorded in Song-won-myuong Soeumin's princple prescription of experience(宋元明 少陰人經驗行用要藥). 4. Soeumin's Prescriptions of the same name in Chobonguen's precriptions and Gabobon's are two;Gwakhanggeunggisan(藿香精氣散) and Bogungikgitang(補中益氣湯). Chobonguen's precriptions were composed of Old prescriptions(古方) except the medications those were considered of wrong Sang Constitutional medications. 5. Soeumin's Prescriptions of the same name in Gabobon's prescriptions and Chopanbon's are nine and except Padudan(巴豆丹) have differences in the kind of medications and quantites. This fact shows that Dongmu(東武) roform the Sasnag Constitutional prescriptions continuously. 6. As this, Dongmu(東武) selected Sasang Constitutional prescription and medication in detail as he has the more experince of treatment.

• Journal of Sasang Constitutional Medicine
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• v.7 no.2
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• pp.21-44
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• 1995

Dong-Mu's philosophy is based on the postulation of "Sa Sim Sin Mul". The attempt to actualize the postulation is seen through the books "Kyuc chigo"and "Dongeuisusebowon". That is to say the physiology, pathology and pharmacology of Sasang based on Dong-Mu's philosoghy all belong to the category of Sa Sim sin Mul. But the interpretations of Sasang prescription have been made as "The recipe for symtoms", it is different from Dong-Mu's view. Appearing of disease can interpretate the strength and weakness o resistance based on the constitution. So, I tried to analogize properties of drugs showed in his writings on the assumption of resistance of the constitution.

• Journal of Sasang Constitutional Medicine
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• v.19 no.2
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• pp.1-10
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• 2007

1. Objectives This paper was written in order to understand prescription's combination of Taeumin. 2. Methods We analysis prescription's combination of Taeumin through pathology and new prescription in Sinchukbon(辛丑本) of ${\ulcorner}$Dongyisusebowon${\lrcorner}$. 3. Results and Conclusions New prescription of Taeumin is combined with a few specific prescription. We analysis new prescription of the exterior disease and get the basic prescription that is Chobonkwon Taeummahwang-tang(太陰麻黃湯), Chobonkwon Saengmac-san(生脈散) and Gunyul ${\cdot}$ Euiin ${\cdot}$ Nabokja(乾栗 ${\cdot}$ 薏苡仁). And we analysis new prescription of the interior disease and get the basic prescription that is Jojung-tang(調中湯), Galgunhagi-tang(葛根解肌湯) and Isunggugo-hwan(二聖救苦丸) of old prescription. However, pharmacology of Eumhyulmogal is different from the other symptom and disease. That contain the pharmacology of Chungsimyunja-tang(淸心蓮子湯). We can't find Chungsimyunja-tang from the discussion of symptom and disease. So we can estimate that Chungsimyunja-tang belongs to the prescription of Eumhyulmogal.

• Journal of Sasang Constitutional Medicine
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• v.35 no.4
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• pp.10-22
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• 2023

Objectives The aim of this study is to explore the mechanism of action and target diseases of Sasang constitutional prescriptions using a multiscale interactome approach. Methods The compound and target information of Sasang constitutional prescriptions were retrieved from various databases such as the TM-MC, STITCH, and TTD. Key targets for Sasang constitutional prescriptions were identified by selecting the top 100 targets based on the number of simple paths within the constructed network. Diffusion profiles for Sasang constitutional prescriptions and diseases were calculated based on a biased random walk algorithm. Potential diseases and key mechanisms of Sasang constitutional prescriptions were identified by analyzing diffusion profiles. Results We identified 144 Sasang constitutional prescriptions and their targets, finding 80 herbs with effective biological targets. A cluster analysis based on selecting up to 100 key targets for each prescription revealed a more cohesive grouping of prescriptions according to Sasang constitution. We then predicted potential diseases for 62 Sasang constitutional prescriptions using diffusion profiles calculated on a multiscale interactome. Finally, our analysis of diffusion profiles revealed key targets and biological functions of prescriptions in obesity and diabetes. Conclusions This study demonstrates the effectiveness of a multiscale interactome approach in elucidating the complex mechanisms and potential therapeutic applications of prescriptions in Sasang constitutional medicine.

• Journal of Sasang Constitutional Medicine
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• v.31 no.3
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• pp.1-8
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• 2019

Objective This study was aimed to research how the recognition of Taeeumin's Mongsul disease was changed from the Gabo edition to the Sinchuk edition of Donguisusebowon, and to present reasonable explanation to the prescription suggested in the Sinchuk edition. Method The original text about Taeeumin Mongsul disease and corresponding prescription in Donguisusebowon Sinchuk edition written in 1901 and Donguisusebowon Gabo edition written in 1894 were compared and analyzed. Furthermore, the literature and articles which are relevant to the prescription and the difference of pathology between the Gabo edition and the Sinchuk edition of Donguisusebowon were searched. Results & Conclusion Sinchuk editon compared to Gabo edition differentiates prescriptions according to the condition of stool, which means that Mongsul disease can occur both in Lung-dryness of Esophagus-Cold pathology and that of Liver-Heat pathology. The prescriptions presented in Sinchuk edition are more specified and in agreement with pathology newly proposed in Sinchuk edition than the prescriptions in Gabo edition. Although Cheongsimyeonja-tang is not mentioned on the original text about Taeeumin Mongsul disease in Sinchuk edition, it can be prescribed for the disease with Lung-dryness of Liver-Heat pathology as Yuldahanso-tang can be. However, Yuldahanso-tang focuses more on Liver-Heat symptoms, while Cheongsimyeonja-tang focuses more on Lung-dryness.

• Journal of Sasang Constitutional Medicine
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• v.27 no.2
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• pp.199-210
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• 2015

Objectives The aim of this study was to make an analysis of clinical characteristics and status of Sasang constitutional medicine of patients with gastrointestinal symptoms who visited a Korean medicine hospital. Methods We studied 287 patients with gastrointestinal symptoms who visited a Korean medicine hospital from March 1, 2010 to February 30, 2012. We retrospectively collected medical history and characteristics of subjects using data of EMR (electronic medical record). Results The proportion of female was higher than male. Most patients was suffered from chronic gastrointestinal disorder. And they were not under western medicine treatment. Among the 287 patients, 139 persons (48.43%) were Soyangin, 88 persons (30.66%) Taeeumin and 60 persons Soeumin (20.91%). The proportion of Soyangin was higher than other Sasang types. In the distribution of prescription according Sasang Constitutional Medicine symptomatology, the proportion of exterior disease's prescription was higher than interior disease in Soyangin (93.53%). And the proportion of interior disease's prescription was higher than exterior disease in Taeeumin (75.86%) and Soeumin (95.00%). The majority of disease were Gyolhyung-symptom (51.54%) and Mangeum-syndrome (46.15%) of exterior disease in Soyangin, Dry-febrile symptom (73.56%) of interior disease in Taeeumin, and Taeeum-syndrome (95.00%) of interior disease in Soeumin. Conclusions By analyzing on clinical characteristics and distribution of Sasang Constitutional Medicine symptomatology could contribute to the development of guideline for treatment of gastrointestinal disease of Sasang Constitutional Medicine.

• Journal of Sasang Constitutional Medicine
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• v.23 no.2
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• pp.164-173
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• 2011

1. Objectives: The purpose of this study is to understand the origin, the progressive changes and the constructive principles of Packhaoleejung-tang (白何烏理中湯) 2. Methods: Packhaoleejung-tang and other related prescriptions were analyzed in terms of their pathological indications, based on "Donguisusebowon Chobongwon (東醫壽世保元 草本卷)", "Donguisusebowon Gabobon (東醫壽世保元 甲午本)", "Donguisusebowon Sinchukbon (東醫壽世保元 辛丑本)", "Dongmuyugo (東武遺稿)", "Shanghanlun (傷寒論)". 3. Results and Conclusions: (1) The origin of Packhaoleejung-tang is leejung-tang from "Shanghanlun (傷寒論)". Packhaoleejung-tang inherited some of the principles from "Shanghanlun (傷寒論)" Insamkeiji-tang (2) "Gabobon(甲午本)"'s one prescription Hyangsaleejung-tang emphasizes the effect of lossen up by using Pogostemonis Herb (藿香),Amomi Fructus(砂仁). "Gabobon(甲午本)"'s another prescription Packhaoleejungtang emphasizes the effect of warm up stomach by using Cinnamomum cassia Blume (桂枝), Allium sativum Linne (獨頭蒜), Cynanchum wilfordii(白何首烏). "Sinchukbon(辛丑本)"'s prescription Packhaobujaleejungtang emphasizes the effect of warm up stomach by using Aconitum carmichaeli(附子) (3) The Packhaoleejung-tang is composed of 7 herbs. Atractlodis Rhizoma White(白朮), Glycyrrhizae Radix(甘草), Paeoniae Radix Alba(白芍藥) support Soeumin's spleen root (脾元), and Zingiberis Rhizoma(乾薑),Cinnamomum cassia Blume (桂枝, Cynanchum wilfordii(白何首烏) warm up stomach. Citri Pericarpium(陳皮) circulate Qi and encourage the descension of Yin.

• Journal of Sasang Constitutional Medicine
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• v.32 no.1
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• pp.12-21
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• 2020

Objectives Dongeuisasangchobongueonbimangrok(DSCB) is a 8-paged material which was written in calligraphy. Although Dongeuisusebowonsasangchobongueon(DSSC) was regarded as a manuscript of Dr. Jema Lee, and the prescriptions of DSCB were very similar to those of DSSC, there are few DSCB-related prescription studies until now. The purpose of this study is to perform a precise comparative study between two manuscripts and to make the difference and commonness clear. Methods A comparison of the components, amounts of the herbal medicine, and treatable diseases of each prescription was carried out. Results DSCB contained a total of 41 prescriptions, including 15 for Taeeumin, 12 for Soeumin, 14 for Soyangin, and 34 prescriptions(82.9%) were the same with DSSC. There was one missing component in 2 prescriptions, and the rest generally had the same component and the treatable diseases, but there was a slight difference in amounts of the herbal medicine between two manuscripts. There were a total of seven kinds of prescription, including 2 for Taeeumin, 3 for Soeumin, and 2 for Soyangin, recorded only in DSCB. Conclusions As this manuscript is valuable that shows his initial prescription thoughts of Dongmu Jema Lee along with DSSC, the understanding Lee's prescription is needed to be studied through cross-review with DSSC and DSCB.