• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2002.11a
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• pp.34-36
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• 2002

Epidermal growth factor (EGF) and insulin-like growth factor-I (IGF-I) have been shown to stimulate proliferation and differentiation of various somatic cells, including placental trophoblasts and also to enhance fetal growth and development when maternally administered. Since an increase of the expression of placental EGF and IGF-I receptors in rat, mouse, and human with the gestation advanced, both EGF and IGF-I were considered to play pivotal roles on fetal growth by regulating some function of placental cells. Amino acids are crucial importance for both maternal and fetal requirements of energy source and essential constituent of fetal mass during pregnancy. Impaired fetal and placental uptake of amino acids has been observed in several models of growth retardation in the rat. Amino acid is concentrated in the fetal side through active transport by amino acid transporters and is one of the important metabolic fuels for the fatal growth. Therefore, at first plasma amino acid concentrations in mothers and fetuses were measured as an index of uphill transport across the placenta associated with EGF and IGF-1. The EGF administration at the concentration of 0, 0.1, or 0.2 $\mu\textrm{g}$/g to pregnant rats from day 18 to 21 of gestation apparently increased fetal/maternal ratio of serum proline concentration and also fatal growth in EGF dose-dependent manner. When IGF-I in doses of 0, 1, 2, and 4 $\mu\textrm{g}$/g were administrated, the ratio of leucine, isoleucine, tryptophan, phenylalanine, tyrosine and also fetal growth significantly increased with a dose-dependent manner. These results suggested that EGF and IGF-I enhanced fatal growth by, as one of its possible mechanisms, promoting placental activity to transfer some amino acid supplies from the mother to the fetus in late pregnancy.

• Journal of Korean Society of Forest Science
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• v.90 no.3
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• pp.324-330
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• 2001

This study was carried out to develop prediction model for fill slope failure of forest road in igneous rock area using fuzzy theory which is non-linear model. The results were summarized as follows. The importance weight of factors on fill slope failure was ranked in the order of fill slope length, fill slope gradient, soil type, aspect, road position and longitudinal slope form. The degree of potential slope failure was high mainly under the such conditions as fill slope length greater than 8m, fill slope gradients steeper than $40^{\circ}$, constituent material with weathered rock, aspect of NE and road on ridge position. The optimal prediction model was developed with 0.15 of optimal coefficient(c) and 3.1165 of ${\lambda}$-value when fuzzy integral value of slope failure possibility is more than 0.5. And the discriminant accuracy was 86.8%, which shows the high availability for discrimination.

• Journal of Plant Biotechnology
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• v.30 no.4
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• pp.387-397
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• 2003

During the first half of twentieth century, even though the importance of non-calorie essential micronutrients of 13 vitamins and 17 minerals has been known to alleviate nutritional disorder; the primary objective of agriculture and plant breeding programs has been to increase the productivity and seed yields, and macronutrients of proteins, fats, and carbohydrates made up the bulk of foodstuff which were used primarily as an energy source. In the last decade it has been found that non-essential micronutrients encompass a vast group of phytochemicals including antioxidants that are not strictly required in the diet but when present at sufficient levels work as health-promoting chemicals. Nowadays agricultural crops are grown for health rather than for food or fiber, and modifying the nutritional compositions of plant foods has become an urgent health issue. To ensure an adequate intake of essential vitamins and minerals, and to increase the consumption of health-promoting phytochemicals, the researches on plant secondary metabolism have been made. The attempt to improve nutritional quality of crops has been blocked by a lack of basic knowledge of plant metabolism. The advent of genomics era enabled new approaches to make crossing regardless of species, family, or phylum barriers, and the accumulation in our basic knowledge on plant secondary metabolism during the coming decade would be tremendous. As the major staple crops contain insufficient amount of many micronutrients, fortification strategy will be a necessary practice. Elevated intake of specific vitamins, C, E, and $\beta$-carotene, mineral selenium, antioxidants, and phytochemicals significantly reduces the risk of chronic disease such as cancer, cardiovascular disorder, diabetis, and other degenerative disease associated with aging. As the attempt to improve the nutritional quality of crops requires the basic knowledges on plant metabolism, plant biochemistry, human physiology, and food chemistry, strong interdisplinary collaboration among plant biotechnologists, human nutritionists, and food scientists will be needed. Inhibition of cancer, cardiovascular disease, and other degenerative disorder may be the biggest goal facing nutritional plant breeders. But the assumption that simply increasing dietary level of any compound will necessarily improve human health is a dangerous idea because many plant secondary products and dietary contaminants have paradoxical (hermetic) effects. Before biotechnical manipulation is undertaken to elevate or reduce any individual constituent of crops, the contribution of the micronutrient to human health must first be investigated.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.36 no.5
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• pp.105-116
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• 2020

In this study, the royal protocols of the Joseon Dynasty, known as uigwes, were reviewed to clarify the materials and structure of Korean traditional walls. For this, the Yeonggeon-and Sanreng-uigwes were thoroughly reviewed, and then the names, materials, and construction methods of the traditional walls were systematically organized. In addition, mix proportions of plastering materials used in the walls were estimated based on the records in the uigwes; these were compared with the ratios specified in the current specifications. As a result of the comprehensive review, it was found that the mix proportions of the plastering materials varied depending on importance of buildings, type of walls, and the raw materials. Based on this, it was concluded that the characteristics of each uigwe should be considered when studying the mix proportion of materials for the traditional walls. It was also found that there were differences between the traditional and modern specifications for the wall constructions. That is, historical records and the specifications currently used were different in terms of constituent materials, construction methods and mix proportions. As a cause of the difference, the disconnection of the traditional methods and the introduction of foreign plastering techniques during the rapid social change in the 20th century were suggested.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.45 no.3
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• pp.173-185
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• 2022

For the smooth implementation and success of smart city projects, it is necessary to recognize that there is a difference in the perception of value judgments or strategic goals among major stakeholders in the planning process. And it is necessary to aim the values and goals of smart cities through reconciliation of these differences. The two major stakeholders in the smart city development project are citizens group and government officials group. Government officials are in charge of establishing and implementing policies for smart city projects, and their value judgments and perceptions influence the policy direction. In these respects, government officials can be an important stakeholder group. Citizens are a group that includes ordinary residents and business owners who live in smart cities and are the ultimate users of infrastructure and facilities. This study investigated the importance perceptions of citizens and government officials, who are the major stakeholders, about the core values and strategic goals that the smart city project aims. Responses were collected using a structured questionnaire to which the AHP methodology was applied. And the priority of perceptions for constituent items was compared for each stakeholder group. Through the comparative analysis results, it was empirically confirmed that there is a difference in the values and goals pursued by the smart city project between stakeholder groups. As an empirical study on the stakeholders of the smart city project, this study is meaningful in contributing to the theoretical development in that it suggests that the conceptual structural model of the smart city strategy system presented in previous studies can be applied in practice.

• Journal of the Korean Society of Clothing and Textiles
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• v.32 no.12
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• pp.1981-1989
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• 2008

Different people buy the same or similar products for different reasons. Benefit segmentation attempts to understand these differences by grouping together people who assign a similar level of importance to the same attributes. We focused on identifying market segments for knit fabrics by comparing the relative attribute preference for knit fabrics according to segmented clusters, and testing to establish if there were significant differences between the preferences of clusters. Three consumer segments emerged, and there were three clusters with different ideal knit profiles: a preferred wool group, a preferred acrylic group, and a preferred long stitch length group. The preferred wool group and the preferred acrylic group rated the mixture ratio as the main attribute that determined their preference, followed by the stitch length. The preferred long stitch length group considered stitch length as being the most important attribute, followed by the mixture ratio. The difference in the preferences for the mixture ratio and stitch length of knit fabrics was the highest between the three clusters, The preferred wool group preferred a knit fabric that has a greater wool mixture ratio and a short stitch length, and the preferred acrylic group and long stitch length group preferred a knit fabric that had a higher acrylic mixture ratio and a short stitch length.

• Journal of Distribution Research
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• v.11 no.2
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• pp.29-57
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• 2006

While a number of studies have recognized the importance of environment of channel systems and consequences of changed environment, only limited studies have dealt with this issue theoretically and practically. The purpose of this study is to empirically validate whether one dimension of environment, called dynamism, has an influence on the relationship characteristics such as transaction specific investment opportunism and conflict or not: further, it is designed to delve into whether these relationship characteristics have any influence on one crucial relationship quality, 'trust' and its two constituent dimensions - credibility and benevolence. In order to provide empirical validation, a survey was conducted to 163 sales office managers at a major newspaper publisher in Korea. An analysis of the data retrieved from this survey indicated that while environmental dynamism has a positive influence on the publisher's opportunism and conflict perceived by the sales office managers, it did not show a direct influence on the transaction specific investment made by the publisher. Furthermore, while publisher's transaction specific investment had a positive influence on the credibility and the benevolence respectively, publisher's opportunism and level of sales office conflict had a negative influence on the credibility and the benevolence respectively. Currently, a publisher is facing an unprecedentedly dynamic environment. This study should provide ample implications for the publisher in establishing trust, which is a crucial condition in developing and maintaining a long-term successful relationship with its sales offices.

• Korean Journal of Environment and Ecology
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• v.31 no.3
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• pp.318-328
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• 2017

In order to provide basic data for the ecological management of forest vegetation in Southern Naeyeon Mountains, A total of 149 sample plots were selected and vegetation survey was carried out by the phytosociological method of the ZM school to classify vegetation types and to grasp ecological characteristics. The forest vegetation was divided into 10 types in terms of species composition, and had a unit hierarchy of 2 community groups, 4 communities, 6 sub-communities and 6 variants. A total of 19 types of physiognomic vegetation were identified based on uppermost dominant species, of which 18 were natural vegetation and 1 was artificial vegetation. As a result of the analysis of the importance values of constituent species, Quercus mongolica, a potentially natural vegetation element, was found to be relatively more important in most stands than other species, and excluding the artificial interference, most of the areas except for some sites would be changed to Q. mongolica forest. In order to understand the spatial distribution of forest vegetation, 1/5,000 large-scale physiognomic vegetation map was created by the uppermost dominant species. As a result, natural vegetation accounted for 98.2%, the number of vegetation patches was 733 and the average area per patch 3.93ha.

• Proceedings of the Korean DIstribution Association Conference
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• 2005.05a
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• pp.165-191
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• 2005

While a number of studies have recognized the importance of environment of channel systems and consequences of changed environment, only limited studies have dealt with this issue theoretically and practically. The purpose of this study is to empirically validate whether one dimension of environment, called dynamism, has an influence on the relationship characteristics such as transaction specific investment, opportunism and conflict or not; further, it is designed to delve into whether these relationship characteristics have any influence on one crucial relationship quality, 'trust' and its two constituent dimensions - credibility and benevolence. In order to provide empirical validation, a survey was conducted to 163 sales office managers at a major newspaper publisher in Korea. An analysis of the data retrieved from this survey indicated that while environmental dynamism has a positive influence on the publisher's opportunism and conflict perceived by the sales office managers, it did not show a direct influence on the transaction specific investment made by the publisher. Furthermore, while publisher's transaction specific investment had a positive influence on the credibility and the benevolence respectively, publisher's opportunism and level of sales office conflict had a negative influence on the credibility and the benevolence respectively. Currently, a publisher is facing an unprecedentedly dynamic environment. This study should provide ample implications for the publisher in establishing trust, which is a crucial condition in developing and maintaining a long-term successful relationship with its sales offices.

• The Korean Journal of Physiology and Pharmacology
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• v.19 no.5
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• pp.389-399
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• 2015

Zinc has been considered as a vital constituent of proteins, including enzymes. Mobile reactive zinc ($Zn^{2+}$) is the key form of zinc involved in signal transductions, which are mainly driven by its binding to proteins or the release of zinc from proteins, possibly via a redox switch. There has been growing evidence of zinc's critical role in cell signaling, due to its flexible coordination geometry and rapid shifts in protein conformation to perform biological reactions. The importance and complexity of $Zn^{2+}$ activity has been presumed to parallel the degree of calcium's participation in cellular processes. Whole body and cellular $Zn^{2+}$ levels are largely regulated by metallothioneins (MTs), $Zn^{2+}$ importers (ZIPs), and $Zn^{2+}$ transporters (ZnTs). Numerous proteins involved in signaling pathways, mitochondrial metabolism, and ion channels that play a pivotal role in controlling cardiac contractility are common targets of $Zn^{2+}$. However, these regulatory actions of $Zn^{2+}$ are not limited to the function of the heart, but also extend to numerous other organ systems, such as the central nervous system, immune system, cardiovascular tissue, and secretory glands, such as the pancreas, prostate, and mammary glands. In this review, the regulation of cellular $Zn^{2+}$ levels, $Zn^{2+}$-mediated signal transduction, impacts of $Zn^{2+}$ on ion channels and mitochondrial metabolism, and finally, the implications of $Zn^{2+}$ in health and disease development were outlined to help widen the current understanding of the versatile and complex roles of $Zn^{2+}$.