• Title/Summary/Keyword: consensus functions

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An Architectural Study on the Spatial Organization and Area Distribution of Community Service Centers in Ansan City (안산시 주민센터의 공간구성 및 면적배분에 관한 연구)

  • Choi, Hyeng-Soon;Park, Jae-Seung
    • Korean Institute of Interior Design Journal
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    • v.20 no.6
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    • pp.3-10
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    • 2011
  • The Community Center is a location designated to enhance the spirit and unity of the residents in the community, through construction and promotion of entertainment, welfare of citizens, and cultural activity. Recently, the roles of the Community Center has become far more diverse, and multiple gadgets and apparatus to encourage the participation and usage of the programs offered at the Community Center. Therefore, the general consensus predicts that the Community Center will continue to encourage further interaction and cooperation, and perform its functions accordingly. The function of this plan is to enable the usage of the basic blueprint of the current Community Center, if in the near future, new buildings were to be constructed, by extracting and deducting the current innovations in the architectural blueprint of the Community Center and the comprising factors within. The specimen of this plan will be the case of Ansan City, and in order to activate this plan, we will contemplate about the functions and placement standards before we actually go through the process of interpreting and analyzing data of the case of Ansan City's Community Center, particularly its comprising factors and changes in their construction plan. We are planning to organize the programs that the Community Center is offering, and process information relating to the base of the edifice, in order to enhance the efficacy and efficiency of the process.

Regulation of Nek6 Functions by Its SUMOylation on the $K^{252}$ Residue

  • Lee, Eun-Jeoung;Hyun, Sung-Hee;Chun, Jae-Sun;Shin, Sung-Hwa;Lee, Kyung-Eun;Park, In-Suk;Kang, Sang-Sun
    • Animal cells and systems
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    • v.11 no.2
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    • pp.205-213
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    • 2007
  • Nek6 belongs to NIMA1 (never in mitosis, gene A) related kinase, which was originally identified in Aspergillus nidulans as a serine/threonine kinase critical for cell cycle progression. We noticed that the putative SUMOylation site is localized on the $K^{252}$ residue in $^{251}FKsD^{254}$ of Nek6, based on the consensus sequence ${\Phi}KxE$; where ${\Phi}$ represents L, I, V or F and x is any amino acid. We observed that the Nek6 SUMO mutant (K252R) has decreased protein kinase activity, nuclear speckle localization and protein stability, compared with that of the Nek6 wild type. However, the Nek6 SUMO mutant increased the cell survival rate of COS-1 cells as determined by FACS analysis. Therefore, our data suggest that SUMOylation on the $K^{252}$ residue of Nek6 is required for its normal functions, such as proper nuclear localization, kinase activity and protein stability, to control cell cycle.

Trend and Perspective of Agricultural Knowledge System in OECD Member Countries (OECD 회원국들의 농업지식체계(AKS) 동향과 전망)

  • Im, Jeong-Nam;Park, Moo-Eon;Park, Kyung-Chul
    • Journal of Agricultural Extension & Community Development
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    • v.7 no.1
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    • pp.13-29
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    • 2000
  • During the last 10 year period, OECD member countries were in a trend of 'less government' from 'more government', thus resulted in restructuring and reducing staffs in government agricultural institutions including the Agricultural Knowledge System. In recognizing the crisis of 'less government', member countries were in a trend of paradigm shift to the 'better government;. In producing and transferring agricultural information, member countries are more concerned about consumers as well as producers as the target of good quality services of the 'better government'. The general consensus of member countries identified the importance of food safety and environmental protection as new agendas for the 21st century. Agricultural Knowledge Systems (AKS) in OECD member countries were in a trend of reorganization in addressing food safety, and agriculture / environmental issues. The approaches, functions and responsibilities were diversified to multi-governmental institutions from the ministry of agriculture. Thus the importance of institutional cooperation and coordination were emphasized more in the newly changed AKS paradigms. The objectives, functions and approaches of AKS in OECD member countries as well as in Korea will be directed to emphasize the importance of environment, sustainable agriculture, food safety, and rural development. They will also focus on establishing mutual cooperative systems among policy makers, consumes, non-governmental organizations, and agri-related organizations as necessary for sustainable development in the future.

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A Design for a Hyperledger Fabric Blockchain-Based Patch-Management System

  • Song, Kyoung-Tack;Kim, Shee-Ihn;Kim, Seung-Hee
    • Journal of Information Processing Systems
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    • v.16 no.2
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    • pp.301-317
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    • 2020
  • An enterprise patch-management system (PMS) typically supplies a single point of failure (SPOF) of centralization structure. However, a Blockchain system offers features of decentralization, transaction integrity, user certification, and a smart chaincode. This study proposes a Hyperledger Fabric Blockchain-based distributed patch-management system and verifies its technological feasibility through prototyping, so that all participating users can be protected from various threats. In particular, by adopting a private chain for patch file set management, it is designed as a Blockchain system that can enhance security, log management, latest status supervision and monitoring functions. In addition, it uses a Hyperledger Fabric that owns a practical Byzantine fault tolerant consensus algorithm, and implements the functions of upload patch file set, download patch file set, and audit patch file history, which are major features of PMS, as a smart contract (chaincode), and verified this operation. The distributed ledger structure of Blockchain-based PMS can be a solution for distributor and client authentication and forgery problems, SPOF problem, and distribution record reliability problem. It not only presents an alternative to dealing with central management server loads and failures, but it also provides a higher level of security and availability.

Universal-, Genus-specific, Species-specific Probes and Primers Design for Microbial Identification

  • Park, Jun-Hyung;Park, Hee-Kyung;Song, Eunsil;Jang, Hyun-Jung;Kang, Byeong-Chul;Lee, Seung-Won;Kim, Hyun-Jin;Kim, Cheol-Min
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2005.09a
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    • pp.399-401
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    • 2005
  • MIPROBE is a web-based tool for design of universal, genus-specific, and species-specific primers and probes. The main functions of MIPROBE are collection of target gene sequences, construction of consensus sequences, collection of candidate primers and probes, and evaluation of candidates by BLAST. Biologists with little computer skills can easily use MIPROBE to design large-scale universal, genus-, and species-specific primers and probes. This software is available at http://www.miprobe.com. Also detailed descriptions of how to use the program are found at this site.

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Capicua is involved in Dorsal-mediated repression of zerknüllt expression in Drosophila embryo

  • Shin, Dong-Hyeon;Hong, Joung-Woo
    • BMB Reports
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    • v.47 no.9
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    • pp.518-523
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    • 2014
  • The maternal transcription factor Dorsal (Dl) functions as both an activator and a repressor in a context-dependent manner to control dorsal-ventral patterning in the Drosophila embryo. Previous studies have suggested that Dl is an intrinsic activator and its repressive activity requires additional corepressors that bind corepressor-binding sites near Dl-binding sites. However, the molecular identities of the corepressors have yet to be identified. Here, we present evidence that Capicua (Cic) is involved in Dl-mediated repression in the zerkn$\ddot{u}$llt (zen) ventral repression element (VRE). Computational and genetic analyses indicate that a DNA-binding consensus sequence of Cic is highly analogous with previously identified corepressor-binding sequences and that Dl failed to repress zen expression in lateral regions of cic mutant embryos. Furthermore, electrophoretic mobility shift assay (EMSA) shows that Cic directly interacts with several corepressor-binding sites in the zen VRE. These results suggest that Cic may function as a corepressor by binding the VRE.

Fast Logic Minimization Algorithm for Programmable-Logic-Array Design (PLA 설계용 고속 논리최소화 알고리즘)

  • 최상호;임인칠
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.22 no.2
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    • pp.25-30
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    • 1985
  • This paper proposes an algorithm to simplify Boolean functions into near minimal sum-of-products for Programmable Logic Arrays. In contrast to the conventional procedures, where the execution time depends on the number of variables, the execution time by this procedure depends on the degree of consensus of base minterms. Thus as the number of variables is increased, the difference of CPU time becomes larger using this new Procedure than using other procedures and consequently the executable range of input function increasing. The algorithm has been implemented on CYEER 170-740 and it's results were compared with those using Arvalo's algorithm.

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Lane Detection Using Gaussian Function Based RANSAC (가우시안 함수기반 RANSAC을 이용한 차선검출 기법)

  • Choi, Yeongyu;Seo, Eunyoung;Suk, Soo-Young;Park, Ju H.;Jung, Ho-Youl
    • IEMEK Journal of Embedded Systems and Applications
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    • v.13 no.4
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    • pp.195-204
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    • 2018
  • Lane keeping assist and departure prevention system are the key functions of ADAS. In this paper, we propose lane detection method which uses Gaussian function based RANSAC. The proposed method consists mainly of IPM (inverse perspective mapping), Canny edge detector, and Gaussian function based RANSAC (Random Sample Consensus). The RANSAC uses Gaussian function to extract the parameters of straight or curved lane. The proposed RANSAC is different from the conventional one, in the following two aspects. One is the selection of sample with different probability depending on the distance between sample and camera. Another is the inlier sample score that assigns higher weights to samples near to camera. Through simulations, we show that the proposed method can achieve good performance in various of environments.

Production and Characterization of Monoclonal Antibodies to Yeast Mitochondrial RNA Polymerase Specificity Factor

  • Lee, Chang-Hwan;Jang, Sei-Heon
    • BMB Reports
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    • v.31 no.6
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    • pp.607-610
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    • 1998
  • Transcription of mitochondrial DNA in the yeast S. cerevisiae depends on recognition of a consensus nonanucleotide promoter sequence by mitochondrial RNA polymerase specificity factor, which is a 43 kDa polypeptide encoded by the nuclear MTF1 gene. Mtf1p has only limited amino acid sequence homology to bacterial sigma factors, but functions in many ways like sigma in that it is required for promoter recognition and initiation of transcription. To analyze the corebinding region of Mtf1p, monoclonal antibodies to this protein were prepared. Recombinant Mtf1p overproduced in E. coli was purified to near homogeneity and used to raise monoclonal antibodies (mAbs). From fused cells screened for Mtf1p mAbs by immunodot blot analysis, 19 positive clones were initially isolated. Further analysis of positive clones by Western blotting resulted in 4 mAbs of Mtf1p.

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The Realities and Problems of Deregulation of Shipping Industry in Major Countries (주요국의 해운산업 규제완화 실태와 문제점에 관한 소고)

  • Kim, Eun-Joo;Han, Nak-Hyun
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.20
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    • pp.153-179
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    • 2003
  • Deregulation is not a matter or problem to be resolved simply by revising a law or a system in a short period of time. Rather, it should be implemented at a steady pace on the basis of a full understanding of the relationships between government regulation and the government's role, taking into account the inherent functions of the market. Moreover, arguments about government regulation and its deregulation vary according to viewpoints and approaches on the part of parties concerned. This makes it more difficult to form a consensus or reach a conclusion in recognizing and resolving the basis of problems at issue. This paper aims to review the shipping industry deregulation of major countries, to analyze Korea's situation and problems of shipping regulation, and to suggest it's improving methods. Although government regulation is a sensitive policy issue, this paper remains relatively at the basic research. Regulation problems should be tackled by interdisciplinary approach. A specific approach in regulation study could not explain exactly the causes and results of government policy

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