• 공학교육연구
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• 제12권1호
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• pp.64-72
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• 2009

본 연구는 공학교육인증제 운영과정에서 강조되고 있는 학습성과 중 리더십 교육과 관련한 CQI 방안을 탐구하는 데 목적이 있다. 이를 위해 본 논문에서는 리더십 교육과 관련된 영남대학교의 사례를 연구하였다. 본 연구를 위해 리더십 교육과 관련된 영남대학교의 교과 및 교과 외 교육과정 분석, 리더십 교육 CQI 방안 마련을 위한 전문가 및 유관 기관 실무자 포커스그룹 면담이 실시되었다. 또한 리더십 캠프 참가자를 대상으로 리더십 역량진단, 리더십 교육 수요 조사, 캠프 만족도 조사를 실시하였다. 리더십 캠프진행을 주관한 데일 카네기 연구소 대구지부의 전문 강사들과 포커스그룹 면담을 실시하고 캠프 기간 동안 비참여관찰법을 통한 내용분석과 질적 면접이 병행되었다. 본 연구 결과를 정리하면 다음과 같다. 첫째, 대학수준의 수학능력 향상방안과 심리적 차원의 역량강화 방안이 동시에 고려되어야 한다. 특히 지방대학이라는 특성을 고려할 때 외국어 능력 향상과 자신감 및 비전 수립을 위한 교육에 역점을 둘 필요가 있다. 둘째, 일회성의 단기 리더십 세미나 및 팀 티칭 형태의 교육을 보완하기 위해서 설계교과목 이수체계도를 활용한 중장기 교육계획 수립 및 리더십 캠프 참가 경험이 있는 학생과 차기 캠프 참가자들간의 멘토-멘티제 운영이 고려될 수 있다. 셋째, 리더십 교육에 역점을 두는 전공, 학과 및 교내외 유관기관 관계자들로 구성된 리더십 교육 자문위원회를 구성함으로써 체계적이고 효과적인 리더십 교육을 실현할 수 있을 것이다.

• 대한수학교육학회지:수학교육학연구
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• 제9권1호
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• pp.351-367
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• 1999

This study aims to study the discourses influencing high school students' concept and attitude toward mathematics, and to examine how gender differences concerning mathematical aptitude are created. This study is based on the results of previous two studies which suggested that mathematical competence differs not only according to gender, region and school year, but also even within the same gender. For this study, 12 students ranking in the top 10% at two co-ed high schools were interviewed to find out 1) what discourses are related to gender and mathematics, 2) in what way these discourses are formulated and gain currency, and 3) how they have affected students in general. Common notions concerning mathematics may be summed up as follows: 1) Most of the students believe that gender difference in mathematical aptitude results because biologically men tend to be strong in mathematics and analytical skills while women tend to have better linguistic ability. This concept can help male students' studying to have a greater learning toward mathematics. 2) A large number of the students believe that male students' studying method is based on comprehension whereas female students' method is based on retention, and hence the former group tends to be better at applying their learning than the latter group. This notion seres to encourage male students and discourage female students from tackling difficult mathematical problems. 3) Many students believe that, although female students may surpass their male counterparts in middle school or the first year of high school, they will eventually fall behind by the 3rd year. Despite research which shows that these common beliefs are not grounded in scientific proof, high-school girls, who may be strong in mathematics, lose self-confidence and feel a sense of crisis. The mechanisms which produce and reinforce such concepts as those mentioned above can be summarized as follows: 1) Regarding the choice of majors and future career paths, parents show different attitudes toward sons and daughters, and this tends to influence high-school girls and hinders them from entering mathematics-related fields. 2) Teachers with value systems based on stereo-typed gender roles affect students a great deal, and give different advice according to gender of their students, for selecting their major fields - for instance, whether to study the natural sciences as opposed to humanities. 3) This study indicates that peer-group behavior, of either support or exclusion, also reinforces the process of internalizing notions of gender difference related to mathematical aptitude. 4) The gender-based notion that men are naturally more inclined to have better mathematical ability has caused male students to choose the natural science subjects and female students to turn to the humanities. The discourses discussed above, propagated in schools and homes, and in the mass media, are continually reinforced along with general gender inequalities in the society at large.

• 지구물리와물리탐사
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• 제12권1호
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• pp.105-113
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• 2009

관측된 파형의 특성들을 해석하여 굴절파와 광각으로 도달한 반사파를 분석하면 결과물로 얻어지는 지각구조 모델의 신뢰도를 향상시킬 수 있으며, 균일한 격자상의 그래프 이론에 기반한 파면법은 복잡한 구조에서도 주시와 파선경로를 효과적으로 계산할 수 있으나, 기본적으로 초동만을 이용하게 되는 단점이 있다. 이번 연구에서는 초동뿐만 아니라 후기 시간대에 도달하는 반사파와 굴절파 및 변환된 P파와 5파의 주시와 파선경로를 계산하기 위하여 다층 모델상에서 표현되는 slowness network 노드에 기반한 수정 파면법을 이용하는 새로운 알고리즘을 개발하였다. 새로운 알고리즘을 통해 모호면의 형태와 변환된 P파와 S파의 위상을 획득하기 위하여 후기 시간대의 Pg파, Pn파 이후에 들어오는 강한신호의 파, 모호면에서 중첩된 PmP를 분석하였다. 제안된 알고리즘의 효용성을 검증하기 위하여 해양-대륙의 전이대와 해령 및 해산에 러한 모델링 연구를 수행하였으며, 2차원 유한차분법을 이용한 수치모형을 통해 그 효용성을 확인하였다. 초동 주시만을 해석에 사용할 경우 대륙-해양 전이대와 해령 및 해산과 같은 모델에서 획득되는 도달파들과 파선경로들의 특성이 각기 다르게 나타나 많은 해석상의 오류가 발생할 수 있는 위험성이 있기 때문에 제안된 기법을 통해 효과적인 해석을 수행할 수 있을 것이다.

• Journal of Genetic Medicine
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• 제8권1호
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• pp.53-57
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• 2011

목 적: 윌슨병은 간조직에 구리의 과도한 침착으로 발병하는 상염색체 열성 유전질환이다. 지금까지 ATP7B 유전자가 유일한 원인유전자로 알려져 왔다. 그러나, 약 15%의 환자에서는 ATP7B 유전자 돌연변이가 발견되지 않는다. 본 연구는 ATP7B 유전자의 돌연변이가 발견되지 않은 윌슨병 환자를 대상으로 새로운 원인 유전자를 발견하기 위하여 시행되었다. 대상 및 방법: ATP7B 돌연변이가 발견되지 않은 12명의 윌슨병 환자를 대상으로 ATP7B 와 상호작용을 하는 것으로 알려진 ATOX1, COMMD1, GLRX, DCTN4와 ZBTB16 유전자의 전사부위와 엑손-인트론 경계부위의 염기서열을 분석하였다. 결 과: DCTN4 유전자의 12번 엑손에 존재하는 c.1084A>G(p.Thr362Ala)를 포함하는 3가지의 변이가 환자에서 발견되었다. in silico 분석을 통해 3가지 변이 중 c.1084A>G가 유일하게 단백질 기능 변화를 일으킬 것으로 예측되었다. 176명의 윌슨병 환자와 414명의 정상인을 대상으로 이 변이의 빈도를 조사한 결과, 정상인보다 윌슨병 환자에서 더 높은 빈도를 나타내었다(상대비, odds ratio [OR]=3.14, 95% 신뢰도=1.36-7.22, P=0.0094). 결 론: 본 연구의 결과는 ATP7B 와 상호작용하는 DCTN4 유전자의 c.1084A>G (p.Thr362Ala) 다형성이 윌슨병의 발병과 연관이 있음을 시사한다.

• 한국환경과학회지
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• 제23권10호
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• pp.1719-1729
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• 2014

This study is carried out in order to bridge the gap to understand the relationships between South Asian and East Asian monsoon systems by comparing the summer (June-September) precipitation of Nepal and South Korea. Summer monsoon precipitation data from Nepal and South Korea during 30 years (1981-2010) are used in this research to investigate the association. NCEP/NCAR reanalysis data are also used to see the nature of large scale phenomena. Statistical applications are used to analyze these data. The analyzed results show that summer monsoon precipitation is higher over Nepal ($1513.98{\pm}159.29mm\;y^{-1}$) than that of South Korea ($907.80{\pm}204.71mm\;y^{-1}$) and the wettest period in both the countries is July. However, the coefficient of variation shows that amplitude of interannual variation of summer monsoon over South Korea (22.55%) is larger in comparison to that of Nepal (10.52%). Summer monsoon precipitation of Nepal is found to be significantly correlated to that of South Korea with a correlation coefficient of 0.52 (99% confidence level). Large-scale circulations are studied to further investigate the relationship between the two countries. wind and specific humidity at 850 hPa show a strong westerly from Arabian Sea to BOB and from BOB, wind moves towards Nepal in a northwestward direction during the positive rainfall years. In case of East Asia, strong northward displacement of wind can be observed from Pacific to South Korea and strong anticyclone over the northwestern Pacific Ocean. However, during the negative rainfall years, in the South Asian region we can find weak westerly from the Arabian Sea to BOB, wind is blowing in a southerly direction from Nepal and Bangladesh to BOB.

• Journal of Gastric Cancer
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• 제17권2호
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• pp.132-144
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• 2017

Purpose: To identify baseline prognostic factors for survival in patients with disease progression, during or after chemotherapy for the treatment of advanced gastric or gastroesophageal junction (GEJ) cancer. Materials and Methods: We pooled data from patients randomized between 2009 and 2012 in 2 phase III, global double-blind studies of ramucirumab for the treatment of advanced gastric or GEJ adenocarcinoma following disease progression on first-line platinum- and/or fluoropyrimidine-containing therapy (REGARD and RAINBOW). Forty-one key baseline clinical and laboratory factors common in both studies were examined. Model building started with covariate screening using univariate Cox models (significance level=0.05). A stepwise multivariable Cox model identified the final prognostic factors (entry+exit significance level=0.01). Cox models were stratified by treatment and geographic region. The process was repeated to identify baseline prognostic quality of life (QoL) parameters. Results: Of 1,020 randomized patients, 953 (93%) patients without any missing covariates were included in the analysis. We identified 12 independent prognostic factors of poor survival: 1) peritoneal metastases; 2) Eastern Cooperative Oncology Group (ECOG) performance score 1; 3) the presence of a primary tumor; 4) time to progression since prior therapy <6 months; 5) poor/unknown tumor differentiation; abnormally low blood levels of 6) albumin, 7) sodium, and/or 8) lymphocytes; and abnormally high blood levels of 9) neutrophils, 10) aspartate aminotransferase (AST), 11) alkaline phosphatase (ALP), and/or 12) lactate dehydrogenase (LDH). Factors were used to devise a 4-tier prognostic index (median overall survival [OS] by risk [months]: high=3.4, moderate=6.4, medium=9.9, and low=14.5; Harrell's C-index=0.66; 95% confidence interval [CI], 0.64-0.68). Addition of QoL to the model identified patient-reported appetite loss as an independent prognostic factor. Conclusions: The identified prognostic factors and the reported prognostic index may help clinical decision-making, patient stratification, and planning of future clinical studies.

• 대한치과기공학회지
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• 제35권4호
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• pp.405-414
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• 2013

Purpose: The purpose of this study was to examine the relationship of the general characteristics of health-related majors to their life expectancy scale, depression scale, health perception scale, subjective wellbeing scale, somatic symptom scale and college life stress scale. And it's also meant to analyze influential factors for their stress about college life. Methods: The subjects in this study were the students who were in the department of dental laboratory technology and the department of dental hygiene at a college located in the region of Iksan, North Jeolla Province. Data were gathered in November and December, 2012. The life expectancy scale, depression scale, health perception scale, subjective wellbeing scale, physical symptom scale, somatic symptom scale and college life stress scale of the general characteristics were analyzed by t-test and one way analyses of variance (ANOVA) and the Duncan's multiple range test at the 95% confidence level to assess the statistical significance. And stepwise multiple regression analysis was conducted to determine what factors would affect the stress of the students about college life. The data were analyzed with the windows ver. 12.0(SPSS GmbH, Germany) statistical software program. Results: Among the general characteristics, there were significant differences according to gender and age in all the variables that were life expectancy scale, depression scale, health perception scale, subjective wellbeing scale, physical symptom scale and college life stress scale. 61.3% of the students responded they slept for six hours or less, and the respondents who slept for six hours or less scored significantly statistically lower in health perception scale, subjective wellbeing scale and physical symptom scale. As for college life stress, the respondents who got depressed more often, whose subjective peace or happiness was lower, whose life expectancy was lower, who had worse physical symptoms, whose living standard was lower and whose academic year was lower were under heavier stress about their college lives. Conclusion: As the worse physical health and worse mental health(life expectancy, depression, health perception, subjective wellbeing and physical symptoms, etc.) of the college students led to heavier stress about college life, how to promote their physical health and mental health should discreetly be considered, and every necessary measure should be taken to improve their physical and mental health.

• 보건행정학회지
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• 제29권3호
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• pp.303-311
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• 2019

Background: Cerebrovascular disease is included in four major diseases and is a disease that has high rates of prevalence and mortality around the world. Moreover, it is a disease that requires a high cost for long-term hospitalization and treatment. This study aims to figure out the correlation between grip strength, which was presented as a simple, cost-effective, and relevant predictor of cerebrovascular disease, and cerebrovascular disease based on the results of a prior study. And furthermore, our study compared model suitability of the model to measuring grip strength and relative grip strength as a predictor of cerebrovascular disease to improve the quality of cerebrovascular disease's predictor. Methods: This study conducted an analysis based on the generalized linear mixed model using the data from the Korea Longitudinal Study of Ageing from 2006 to 2016. The research subjects consisted of 9,132 middle old age people aged 45 years or older at baseline with no missing information of education level, gender, marital status, residential region, type of national health insurance, self-related health, smoking status, alcohol use, and economic activity. The grip strength was calculated the average which measured 4 times (both hands twice), and the relative grip force was divided by the body mass index as a variable considering the anthropometric figure that affects the cerebrovascular disease and the grip strength. Cerebrovascular diseases, a dependent variable, were investigated based on experiences diagnosed by doctors. Results: An analysis of the association between grip strength and found that about 0.972 (odds ratio [OR], 0.972; 95% confidence interval [CI], 0.963-0.981) was the incidence of cerebral vascular disease as grip strength increased by one unit increase and the association between relative grip strength and cerebrovascular disease found that about 0.418 (OR, 0.418; 95% CI, 0.342-0.511) was the incidence of cerebral vascular disease as relative grip strength increased by unit. In addition, the model suitability of the model for each grip strength and relative grip strength was 11,193 and 11,156, which means relative grip strength is the better application to the predictor of cerebrovascular diseases, irrespective of other variables. Conclusion: The results of this study need to be carefully examined and validated in applying relative grip strength to improve the quality of predictors of cerebrovascular diseases affecting high mortality and prevalence.

• 생명과학회지
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• 제31권10호
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• pp.922-928
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• 2021

본 연구는 우리나라 전통 장류인 된장과 청국장의 미생물 분포와 시료간의 미생물학적 차이에 대해 차세대 염기서열 분석법(NGS)을 이용하여 분석하였다. α-diversity 분석 결과 된장에서 종 추정치와 풍부도가 통계학적으로 유의한 수준으로 높은 것으로 나타났다. 세균 분포를 분석한 결과 문 수준에서 Firmicutes가 된장에서 97.02%, 청국장에서 99.67%를 차지하여 공통적으로 가장 우점하는 것으로 나타났으며, 속 수준에서는 된장과 청국장에서 Bacillus가 각각 71.70%, 59.87%를 차지하여 가장 우점하는 것으로 확인되었다. 된장과 청국장의 미생물 분포에 차이가 있는지 분석하기 위해 PERMANOVA 분석을 수행한 결과 된장과 청국장의 미생물 분포에 통계학적으로 유의한 수준으로 차이가 나는 것으로 나타났다. 각 된장과 청국장 미생물 군집을 대표하는 biomarker를 분석하기 위해 LEfSe분석을 수행한 결과 된장에서 Bacillus subtilis, Tetragenococcus halophilus, Clostridium arbusti가 상대적으로 많이 분포하였으며, 청국장에서는 Bacillus thermoamylovorans, Enterococcus faecium, Lactobacillus sakei가 상대적으로 많이 분포하는 것으로 나타났다. 본 연구를 통해 콩을 주원료로 하는 우리나라 대표 전통장류인 된장과 청국장의 시료별 유사성과 차이점에 대한 미생물 분포를 정의하고 전통장류의 생화학적, 생리학적 특성과 미생물 분포의 상관관계를 규명하기 위한 기초 연구자료로 활용할 수 있을 것으로 기대된다.

• 한국터널지하공간학회 논문집
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• 제12권1호
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• pp.1-14
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• 2010

지금까지 Martin 등(1999)의 선형관계식에 의한 스폴링 깊이 평가법이 널리 이용되어 왔으나, 이 방법은 원형 공동에만 적용될 수 있으며 실제 스폴링 발생현장에 적용한 결과 과대평가하는 결과를 보였다. 한편, 스폴링 폭을 평가하는 방법은 아직까지 제시되어 있지 않아 적절하게 평가가 이루어지지 못했다. 그러나, 스폴링 영역에 대한 적절한 보강을 위해서는 스폴링 깊이와 스폴링 폭에 대한 정량적인 평가가 필수적이다. 본 연구에서는 스폴링 관측사례와 스폴링 발생현장의 CWFS 수치해석 사례를 통해 3가지 스폴링 평가인자의 함수로 표현되는 정규화 스폴링 깊이와 정규화 스폴링 폭의 선형회귀식을 도출하였고, 통계추론에 의한 95% 신뢰구간을 통해 회귀식의 신뢰성을 검증하였다. 제안된 선형회귀식으로부터 예측된 스폴링 깊이와 스폴링 폭은 회귀관계의 분산도를 고려한 가중치를 적용함으로써 현장관측결과를 합리적으로 예측할 수 있었다.