• 제목/요약/키워드: concordance

검색결과 443건 처리시간 0.026초

독-한 명사구 기계번역시스템의 구축 (The Construction of a German-Korean Machine Translation System for Nominal Phrases)

  • 이민행;최승권;최경은
    • 한국언어정보학회지:언어와정보
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    • 제2권1호
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    • pp.79-105
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    • 1998
  • This paper aims to describe a German-Korean machine translation system for nominal phrases. Besides, we have two subgoals. First, we are going to revea linguistic differences between two languages and propose a language-informational method fo overcome the differences. The method is based on an integrated model of translation knowledge, efficient information structure, and concordance selection. Then, we will show the statistical results about translation experiment and its evaluation as an evidence for the adequacy of our linguistic method and translation system itself.

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Risk Stratification of Early Stage Oral Tongue Cancers Based on HPV Status and p16 Immunoexpression

  • Ramshankar, Vijayalakshmi;Soundara, Viveka T.;Shyamsundar, Vidyarani;Ramani, Prathiba;Krishnamurthy, Arvind
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권19호
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    • pp.8351-8359
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    • 2014
  • Background: Recent epidemiological data have implicated human papilloma virus (HPV) infection in the pathogenesis of head and neck cancers, especially oropharyngeal cancers. Although, HPV has been detected in varied amounts in persons with oral dysplasia, leukoplakias and malignancies, its involvement in oral tongue carcinogenesis remains ambiguous. Materials and Methods: HPV DNA prevalence was assessed by PCR with formalin fixed paraffin embedded sections (n=167) of oral tongue squamous cell carcinoma patients and the physical status of the HPV16 DNA was assessed by qPCR. Immunohistochemistry was conducted for p16 evaluation. Results: We found the HPV prevalence in tongue cancers to be 51.2%, HPV 16 being present in 85.2% of the positive cases. A notable finding was a very poor concordance between HPV 16 DNA and p16 IHC findings (kappa<0.2). Further molecular classification of patients based on HPV16 DNA prevalence and p16 overexpression showed that patients with tumours showing p16 overexpression had increased hazard of death (HR=2.395; p=0.005) and disease recurrence (HR=2.581; p=0.002) irrespective of their HPV 16 DNA status. Conclusions: Our study has brought out several key facets which can potentially redefine our understanding of tongue cancer tumorigenesis. It has emphatically shown p16 overexpression to be a single important prognostic variable in defining a high risk group and depicting a poorer prognosis, thus highlighting the need for its routine assessment in tongue cancers. Another significant finding was a very poor concordance between p16 expression and HPV infection suggesting that p16 expression should possibly not be used as a surrogate marker for HPV infection in tongue cancers. Interestingly, the prognostic significance of p16 overexpression is different from that reported in oropharyngeal cancers. The mechanism of HPV independent p16 over expression in oral tongue cancers is possibly a distinct entity and needs to be further studied.

복합 생체신호를 이용한 능동형 스피닝 트레이닝 시스템 (Active Spinning Training System using Complex Physiological Signals)

  • 김철민;강경헌;김은석
    • 한국콘텐츠학회논문지
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    • 제15권7호
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    • pp.591-600
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    • 2015
  • 최근 건강에 대한 관심이 높아짐에 따라 운동 프로그램을 스스로 학습하고 즐길 수 있는 능동형 피트니스 시스템에 대한 연구가 활발히 진행되고 있다. 본 논문에서는 운동 참여자의 생체신호에서 획득한 생체상태와 운동 정보를 이용하여 개인 수준에 맞는 스피닝 트레이닝 프로그램을 자기 주도 방식으로 학습 및 체험할 수 있게 하는 능동형 스피닝 트레이닝 시스템을 설계하고 구현하였다. 제안 시스템은 운동 참여자의 뇌파와 맥파 신호를 통해 생체 상태를 분석하고, 골격 동작을 실시간 인식하여 검출된 스피닝 동작 일치율과 운동량을 반영하여 운동 참여자에게 적합한 난이도의 스피닝 프로그램을 제공한다. 또한, 가상 스피닝 강사를 통해 올바른 동작을 제시하고 참여자의 동작 일치율에 따라서 난이도를 조절함으로써 운동 효과를 높일 수 있도록 하였다. 다양한 사용자들에 대한 실험을 통해 제안시스템이 비교적 짧은 시간에 유효한 운동 효과를 얻는데 도움이 됨을 확인할 수 있었다.

Accuracy of the 2008 Simplified Criteria for the Diagnosis of Autoimmune Hepatitis in Children

  • Arcos-Machancoses, Jose Vicente;Busoms, Cristina Molera;Tatis, Ecaterina Julio;Bovo, Maria Victoria;Bernabeu, Jesus Quintero;Goni, Javier Juamperez;Martinez, Vanessa Crujeiras;Martin de Carpi, Javier
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제21권2호
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    • pp.118-126
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    • 2018
  • Purpose: Classical criteria for diagnosis of autoimmune hepatitis (AIH) are intended as research tool and are difficult to apply at patient's bedside. We aimed to study the accuracy of simplified criteria and the concordance with the expert diagnosis based on the original criteria. Methods: A cohort of children under study for liver disorder was selected through consecutive sampling to obtain the prevalence of AIH within the group of differential diagnoses. AIH was defined, based on classical criteria, through committee review of medical reports. Validity indicators of the simplified criteria were obtained in an intention to diagnose approach. Optimal cut-off and the area under the receiver operating characteristic (ROC) curve were calculated. Results: Out of 212 cases reviewed, 47.2% were AIH. For the optimal cut-off (6 points), the simplified criteria showed a sensitivity of 72.0% and a specificity of 96.4%, with a 94.7% positive and a 79.4% negative predictive value. The area under the ROC curve was 94.3%. There was a good agreement in the pre-treatment concordance between the classical and the simplified criteria (kappa index, 0.775). Conclusion: Simplified criteria provide a moderate sensitivity for the diagnosis of AIH, but may help in indicating treatment in cases under suspicion with 6 or more points.

한국어판 WHO-CIDI(Composite International Diagnostic Interview)-사회 공포증의 개발 : 타당도 및 신뢰도 검사 (Development of Korean Version of WHO-CIDI(Composite International Dignostic Interview)-Social Phobia : Its Validity and Reliability)

  • 서주원;오강섭;이시형
    • 정신신체의학
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    • 제8권2호
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    • pp.191-200
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    • 2000
  • 연구목적 : 본 연구의 목적은 한국어판 CIDI(Composite International Diagnostic Interview) 사회공포증의 타당도, 신뢰도를 알아보고자 하는 것이다. 방법 : DSM-IV 진단기준에 의하여 사회공포증으로 진단한 50명의 환자를 대상으로 한국어판 CIDI-사회공포증을 실시하여 임상진단과의 일치도를 보았고 이중 20명에 대하여서는 두 명의 면담자가 각각 실시하여 면담자간 일치도를 측정하였다. 결과 : 50명에 대한 임상진단과 일치도를 통한 타당도는 0.74로 나타났으며 두 명의 면담자간 일치도를 통한 신뢰도(kappa)는 0.75로 나타났다. 결론 : 한국어판 CIDI-사회공포증은 높은 신뢰도 및 타당도를 가지고 있었다. 따라서 일반인구 및 임상집단을 대상으로 사회공포증을 진단하기에 유용한 도구로 판명되었다.

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Comparison of Mammography in Combination with Breast Ultrasonography Versus Mammography Alone for Breast Cancer Screening in Asymptomatic Women

  • Boonlikit, Sarawan
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권12호
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    • pp.7731-7736
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    • 2013
  • Aim: To compare the agreement of screening breast mammography plus ultrasound and reviewed mammography alone in asymptomatic women. Materials and Methods: All breast imaging data were obtained for women who presented for routine medical checkup at National Cancer Institute (NCI), Thailand from January 2010 to June 2013. A radiologist performed masked interpretations of selected mammographic images retrieved from the computer imaging database. Previous mammography, ultrasound reports and clinical data were blinded before film re-interpretation. Kappa values were calculated to assess the agreement between BIRADS assessment category and BIRADS classification of density obtained from the mammography with ultrasound in imaging database and reviewed mammography alone. Results: Regarding BIRADS assessment category, concordance between the two interpretations were good. Observed agreement was 96.1%. There was moderate agreement in which the Kappa value was 0.58% (95%CI; 0.45, 0.87). The agreement of BI-RADS classification of density was substantial, with a Kappa value of 0.60 (95%CI; 0.54, 0.66). Different results were obtained when a subgroup of patients aged ${\geq}60$ years were analyzed. In women in this group, observed agreement was 97.6%. There was also substantial agreement in which the Kappa value was 0.74% (95%CI; 0.49, 0.98). Conclusions: The present study revealed that concordance between mammography plus ultrasound and reviewed mammography alone in asymptomatic women is good. However, there is just moderate agreement which can be enhanced if age-targeted breast imaging is performed. Substantial agreement can be achieved in women aged ${\geq}60$. Adjunctive breast ultrasound is less important in women in this group.

색인사 연구

  • 박준식
    • 한국도서관정보학회지
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    • 제2권
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    • pp.23-59
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    • 1975
  • Indexes has not devcloped as an independent branch in library science from the beginning, but it has gradually evolved in a clo~eas sociation with catalog and under the direct influence of the development of publishing pro cesses and of the rapid social changes. Historically, index in the West can be traced back to eariler concordance. On the other hand, index in the Bast does not show a continuous development. It started with book catnlog, but other types of indexing were later 'adopted from the West. Indexing in the West and in the East can be summarized as follows: 1) In the West, Taylor considers Gesner's Pandectae was the first index but the Concordance of the Bible in 1247 was the first true index. Indexing method was first established later in 1545 in Gesner's Partitiones which appeared in three volumes. Classified index appeared after Partitions, but alphabetically ordered index was not developed until th eseventeenth century. The pxiodical index of La France S~auante in 1683 proved -its value, and Poole's An Alphabetical Index in the nineteenth century became the turning point in the development of indexing. After Poole's Index appeared periodical index and book catalog gradually began to be treated separately, and subject index and cross reference were incorporated into indexing. Also dictionary arrangement of the indexed items was adopted in the second half of the nincteenth, century after Charles A. Cutter developed his theory of rules for dictionary catalog and systematic studies of indexing were carried out by many scholars. In the twentieth century, index was mainly developed in the United States of America, especially by Wilson publishing Company. The general trend is to move away from the gcncral index to subject index. Also the ncwspapcr indcx such as The Times I~zdcx is 21 landmark in the history cf indcxing. 2) In China, thcs arc somc cvidcnccs that $Bizgluh(&), $ was the first indcx, but unforlunatcly the book itsclf has not been found as yet.

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편마비 환자의 상지 재활 기기 운용을 위한 관절 각 추정 기법에 관한 연구 II (Study on The Estimation Method of the Joint for the Operation of the Upper Limb Rehabilitation Equipment for Hemiplegic Patients II)

  • 송기선;엄수홍;이응혁
    • 재활복지공학회논문지
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    • 제8권4호
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    • pp.313-318
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    • 2014
  • 본 논문은 편마비환자들의 상지재활 기기 운용방법으로 건측에서 관성측정장치를 기반으로 한 관절각 추정 기법과 착용 과정에서 발생하는 측정축 뒤틀림을 보정하는 기법을 제안한다. 제안하는 기법을 검증하기 위해 실험자 왼팔의 상완과 전완에 관성측정장치를 부착하였으며, 임의의 자세를 촬영하여 검출한 실제 관절 각과 관절각 추정한 각과 비교하여 검증 하였다. 그리고 측정축 뒤틀림을 보정하는 기법을 적용 전/후를 비교하여 검증하였다. 실험 결과 측정축 뒤틀림 보정을 적용전은 관절각 일치율이 89.16%로 저조한 일치율을 보였으나, 측정축 뒤틀림을 보정한 후에 관절각 일치율은 93.28%의 일치율로 4.12% 개선되었음을 확인 하였다.

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체형 안면 소증 및 성정 특성 기반 사상체질 진단 프로그램 개발 (A Development of Sasang Constitution Diagnosis Program Based on Characteristics of Body Shape Face Physiological Symptom and Personality)

  • 장은수;박기현;백영화;이시우;김성훈;주종천
    • 사상체질의학회지
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    • 제24권1호
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    • pp.21-31
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    • 2012
  • 1. Objectives : In this study we derived constitutional characteristics both by using questionnaire on character and symptom and by collecting objective measurement data through face, body shape. Furthermore, by developing a program, we intend to help one's diagnosis of Sasang constitution. 2. Methods : Through November 2007 to July 2009, we obtained questionnaire, face, and body shape data of 958 constitution confirmed subjects within the age range of 10-80 from 19 oriental medical facilities in the country. According to sex, we divided the subjects into two groups as real constitution and non-constitution group respectively. We analyzed the questionnaire through chi-square test (p<.01) and facial and body shape data through unpaired T-test (p<.01). By using weight law for questionnaire and euclidean distance for body shape and face data, we expressed constitution possibility to develop a supplementary program. 3. Results : The concordance rates of constitutional diagnosis by using the program for Taeeumin, Soeumin, Soyangin are, 76.7%, 61.5%, 67.4% resulting in 69.6% in male and 64.1%, 64.7%, 65.1%, resulting in 64.7% In female respectively. New cases tested on the program showed concordance rate of 65% in male and 62% in female with real constitution. 4. Conclusion : The constitutional diagnostic program based on the face, body shape and questionnaire, may have significant meaning as a supplementary tool in the constitutional diagnosis for clinical expert.

Verification of a computer-aided replica technique for evaluating prosthesis adaptation using statistical agreement analysis

  • Mai, Hang-Nga;Lee, Kyeong Eun;Lee, Kyu-Bok;Jeong, Seung-Mi;Lee, Seok-Jae;Lee, Cheong-Hee;An, Seo-Young;Lee, Du-Hyeong
    • The Journal of Advanced Prosthodontics
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    • 제9권5호
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    • pp.358-363
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    • 2017
  • PURPOSE. The purpose of this study was to evaluate the reliability of computer-aided replica technique (CART) by calculating its agreement with the replica technique (RT), using statistical agreement analysis. MATERIALS AND METHODS. A prepared metal die and a metal crown were fabricated. The gap between the restoration and abutment was replicated using silicone indicator paste (n = 25). Gap measurements differed in the control (RT) and experimental (CART) groups. In the RT group, the silicone replica was manually sectioned, and the marginal and occlusal gaps were measured using a microscope. In the CART group, the gap was digitized using optical scanning and image superimposition, and the gaps were measured using a software program. The agreement between the measurement techniques was evaluated by using the 95% Bland-Altman limits of agreement and concordance correlation coefficients (CCC). The least acceptable CCC was 0.90. RESULTS. The RT and CART groups showed linear association, with a strong positive correlation in gap measurements, but without significant differences. The 95% limits of agreement between the paired gap measurements were 3.84% and 7.08% of the mean. The lower 95% confidence limits of CCC were 0.9676 and 0.9188 for the marginal and occlusal gap measurements, respectively, and the values were greater than the allowed limit. CONCLUSION. The CART is a reliable digital approach for evaluating the fit accuracy of fixed dental prostheses.