• 제목/요약/키워드: compounding

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The Pre-Clinical Experiments of the Compounding Antipyretic Analgesics (배합해열진통제(配合解熱鎭痛劑)의 전임상시험(前臨床試驗)에 관(關)한 연구(硏究))

  • Kim, Jae-Wan
    • Journal of Pharmaceutical Investigation
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    • v.10 no.1
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    • pp.4-12
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    • 1980
  • The studies of the compounding analgestic antipyretics were examined by the converted Koster's method (mice) and the converted Mac Donald's method (mice) induced on the three assumption crossover test. And the following results were found. 1. The same effect of the writhing inhibition in this compounding antipyretic dosage by it's oral administration is as follows. Aminopyrine 100mg/kg. (standard), aminopyrine 50mg/kg compounding with chlorpheniramine maleate 2mg/kg., compounding with diphenhydramine hydrochloride 8mg/kg., compounding with atropine sulfate 0.2mg/kg., or compounding with scopolamine hydrobromide 0.2mg/kg. And aspirin80mg/kg., Salicylamide 90mg/kg., sulpyrine 60mg/kg., or phenacetin 70mg/kg. compounding with the same dosage of the adjutants above. 2. The elevation-rate of the reaction threshold in this compounding antipyretic dosage by it's oral administration calculate as follows. When the elevation-rate (ER) of aminopyrine (100mg./kg.) is 1.00 (Standard), ER of aminopyrine (50mg./kg.) compounding with chlorpheniramine maleate (2mg./kg.) calculated 1.42, aspirin (80.mg./kg.) compounding with diphenhydramine hydrochloride (80mg./kg.) calculated 1.18, salicylamide (90mg./kg.) compounding with chlorpheniramine maleate (2mg./kg.) calculated 1.15, sulpyrine (60mg./kg.) compounding with chlorpheniramine maleate(2mg./kg.) calculated 1.28, and ER phenacetin (70mg./kg.) compounding with chlorpheniramine maleate (2mg./kg.) calculated 1.19.

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Acquisition of English Complex Predicates in SLA

  • Park, Hye-Son
    • English Language & Literature Teaching
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    • v.12 no.2
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    • pp.177-194
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    • 2006
  • Snyder (2001) proposes that complex predicate constructions are interrelated by shared dependence on a single parameter, the Compounding Parameter, and that the global application of the parameter explains the simultaneous acquisition of the complex predicate constructions and N-N compounds in L1 acquisition of English. Slabakova (2002) examined the status of the Compounding Parameter in the acquisition of L2 Spanish by instructed learners. The result of the study, however, was not compatible with the prediction of the Compounding Parameter, possibly due to the availability of negative evidence in the input. Building upon Slabakova's study, this paper examines the status of the Compounding Parameter in naturalistic L2 learning. It is shown that the naturalistic L2 learners do not acquire the complex predicate constructions and N-N compounds concurrently contra to the prediction of the Compounding Parameter. It is suggested that the validity of the Compounding Parameter as a theoretical construct be reconsidered.

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Improved Attenuation Estimation of Ultrasonic Signals Using Frequency Compounding Method

  • Kim, Hyungsuk;Shim, Jaeyoon;Heo, Seo Weon
    • Journal of Electrical Engineering and Technology
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    • v.13 no.1
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    • pp.430-437
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    • 2018
  • Ultrasonic attenuation is an important parameter in Quantitative Ultrasound and many algorithms have been proposed to improve estimation accuracy and repeatability for multiple independent estimates. In this work, we propose an improved algorithm for estimating ultrasonic attenuation utilizing the optimal frequency compounding technique based on stochastic noise model. We formulate mathematical compounding equations in the AWGN channel model and solve optimization problems to maximize the signal-to-noise ratio for multiple frequency components. Individual estimates are calculated by the reference phantom method which provides very stable results in uniformly attenuating regions. We also propose the guideline to select frequency ranges of reflected RF signals. Simulation results using numerical phantoms show that the proposed optimal frequency compounding method provides improved accuracy while minimizing estimation bias. The estimation variance is reduced by only 16% for the un-compounding case, whereas it is reduced by 68% for the uniformly compounding case. The frequency range corresponding to the half-power for reflected signals also provides robust and efficient estimation performance.

Surface Modification of Colloidal Silica Nanoparticles: Controlling the size and Grafting Process

  • He, Wentao;Wu, Danhua;Li, Juan;Zhang, Kai;Xiang, Yushu;Long, Lijuan;Qin, Shuhao;Yu, Jie;Zhang, Qin
    • Bulletin of the Korean Chemical Society
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    • v.34 no.9
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    • pp.2747-2752
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    • 2013
  • Surface modification of colloidal silica nanoparticles without disrupting the electric double layer of nanoparticles is a major challenge. In the work, silane was employed to modify colloidal silica nanoparticles without inducing bridge flocculation obviously. The effect of pH value of the silica sol, the amount of silane in feed, and reaction temperature on the graft amount and the final size of modified particles was investigated. The increased weight loss by TG and the appearance of $T_2$ and $T_3$ except for $Q_2$ and $Q_3$ signals by CP/MAS $^{29}Si$ NMR of the modified samples verified the successful grafting of silane. The graft amount reached 0.57 mmol/g, which was slightly lower than theory value, and the particle size remained nearly the same as unmodified particles for acidic silica sol at the optimum condition. For alkaline silica sol after modification, aggregates composed of several nanoparticles connected together with silane moleculars as the bridge appeared.

Studies on it's Practical Application to Auto Pneumatic Tyre and Manufacture of CBR (cis-1,4-polytutadiene Rubber) (Part. 3) On the Blend of Diene rubber and Turfdene rubber (CBR의 제조(製造) 및 이를 자동차(自動車) Tyre에 활용(活用)하는데 관(關)한 연구(硏究)(제3보(第三報)) Diene rubber와 Turfdene rubber와의 blend에 관(關)하여)

  • Lee, Hyun-O;Lee, Young-Kil
    • Elastomers and Composites
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    • v.7 no.1
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    • pp.21-37
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    • 1972
  • We have studied the blending effects of Diene NF 35R and Turfdene 1000R at various blending ratios 100/0, 70/30, 50/50, 30/70, 0/100, and of carbon black NAF and ISAF at various compounding ratios of 55 PHR, 65PHR, 75PHR for tyre tread rubber. As the results, it was found that; 1. For tyre tread rubber, as the blending ratio, Diene NF 35R/Turfdene 1000R, indicated 30/70, the physical properties we examined were most excellent. 2. Excellent result was obtained in case of carbon black compounding ratio of 63PHR. The compounding of ISAF made better result than that of HAF for tensile strength, tearing strength, and abrasion quantity. 3. Heat buildup obtained from compounding carbon black HAF indicated low temperature than that from compounding carbon black ISAF. As the compounding amount of carbon black increased, the heat buildup improved, and as the blending amount of Diene NF 35R decreased, the heat buildup dropped. 4. Carbon black was more efficient to Turfdene 1000R than to Diene NF 35R. 5. In this pysical properties, mooney viscosity, and mooney scorch time, as the compounding amount of carbon black increased, the values of mooney viscosity increased, but that of mooney scorch time dropped.

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Spatial Compounding of Ultrasonic Diagnostic Images for Rotating Linear Probe with Geometric Parameter Error Compensation

  • Choi, Myoung Hwan;Bae, Moo Ho
    • Journal of Electrical Engineering and Technology
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    • v.9 no.4
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    • pp.1418-1425
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    • 2014
  • In ultrasonic medical imaging, spatial compounding of images is a technique where ultrasonic beam is steered to examine patient tissues in multiple angles. In the conventional ultrasonic diagnostic imaging, the steering of the ultrasonic beam is achieved electronically using the phased array transducer elements. In this paper, a spatial compounding approach is presented where the ultrasonic probe element is rotated mechanically and the beam steering is achieved mechanically. In the spatial compounding, target position is computed using the value of the rotation axis and the transducer array angular position. However, in the process of the rotation mechanism construction and the control system there arises the inevitable uncertainties in these values. These geometric parameter errors result in the target position error, and the consequence is a blurry compounded image. In order to reduce these target position errors, we present a spatial compounding scheme where error correcting transformation matrices are computed and applied to the raw images before spatial compounding to reduce the blurriness in the compounded image. The proposed scheme is illustrated using phantom and live scan images of human knee, and it is shown that the blurriness is effectively reduced.

Studies on It's Practical Application to Auto Pneumatic Tyre and Manufacture of CBR (Cis-1,4-Polybutadiene Rubber) (Part. 4) On the Blend of Diene rubber and Alfin rubber (CBR의 제조(製造) 및 이를 자동차(自動車) Tyre에 활용(活用)하는데 관(關)한 연구(硏究)(제4보(第四報)) Diene Rubber와 Alfin Rubber와의 Blend에 관(關)하여)

  • Lee, Hyun-O;Lee, Young-Kil;Kim, Ki-Yup
    • Elastomers and Composites
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    • v.8 no.1
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    • pp.33-51
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    • 1973
  • We have studied the blending effects of Diene NF 35 R and Alfin 1530 at various blending ratios, 100/0, 70/30, 50/50, 30/70, 0/100, and of carbon black HAF-HS and ISAF-HS at various compounding ratios of 45 PHR, 55 PHR, 65 PHR, for tyre tread rubber. As the results, it was found that; 1. For tyre tread rubber, as the blending ratio, AR 1530/Diene NF 35R, indicated 70/30, the physical properties we examined were most excellent. 2. Excellent result was obtained in the case of carbon black compounding ratio of 55 PHR. The compounding of ISAF-HS made better result than that of HAF-HS for tensile strength, but the compounding of HAF-HS made better result than that of ISAF-HS for tearing strength and best result for abrasion quantity. 3. Heat buildup obtained from compounding carbon black HAF-HS indicated low temperature than that from compounding carbon black HAP-HS. As the compounding amount of carbon black increased, and as the blending amount of AR 1530 decreased, the heat buildup increased. 4. Carbon black was more efficient to AR 1630 than io Diene NF 35 R. 5. In the physical properties, mooney viscosity and mooney scorch time, as the compounding amount of carbon black increased, the values of mooney viscosity increased, but that of mooney scorch time had a max. point at the compoundiug amount of carbon black, 55 PHR.

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Influence of Reaction Conditions on the Grafting Pattern of 3-Glycidoxypropyl trimethoxysilane on Montmorillonite

  • He, Wentao;Yao, Yong;He, Min;Kai, Zhang;Long, Lijuan;Zhang, Minmin;Qin, Shuhao;Yu, Jie
    • Bulletin of the Korean Chemical Society
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    • v.34 no.1
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    • pp.112-116
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    • 2013
  • Surface modification of montmorillonite (MMT) with 3-glycidoxypropyl trimethoxysilane (3GTO) in mild methanol/water mixture has been investigated in detail. The influence of reaction conditions (including silane concentration in feed, reaction time and reaction temperature) on the grafting amount and yield of silane, and further on the grafting pattern of silanes was studied by thermogravimetric analysis, elemental analysis, X-ray diffraction (XRD) and BET. Higher silane concentration, longer reaction time and higher reaction temperature are all benefit to higher grafting amount. When the grafting reaction was performed with 3 mmol/g silane concentration, at $90^{\circ}C$ for 24 h, the grafted amount and yield of silane reached 1.4443 mmol/g and 30%, respectively. Based on the XRD and BET data analysis, a speculation that the grafting pattern of silanes was concentration dependence was proposed.

Studies on it's practical Application to Auto Pneumatic tyre and Manufacture of CBR (Part 1.) On the Blend of CBR and SBR (CBR의 제조(製造) 및 이를 자동차(自動車) tyre에 활용(活用)하는데 관(關)한 연구(硏究)(제1보(第一報)) CBR와 SBR의 Blend에 관(關)하여)

  • Lee, Hyan-O;Lee, Young-Kil
    • Elastomers and Composites
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    • v.6 no.1
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    • pp.53-70
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    • 1971
  • We have studied the blending effects of cis-1,4-polybutadiene (CBR) and styrene-tutadiene rubber at various blending ratios of 100 : 0, 70 30, 50 : 50, 30 : 70, 0 : 100, and of carbon black ISAF and HAP at various compounding ratios of 45 PHR, 55 PHR, 65 PHR, for tyre tread rubber. The results obtained are summerized as follows; 1. For tyre tread rubber, it was found to increased efficiency to use SBR polymer only than to use the blending ratio CB/SBR=30/70 below. But it was observed that the latter was adapted for the bus or truck tyre and the former for the passenger tyre. 2. Excellent efficiency was obtained in case of carbon black compounding ratio of 55%, and also the compounding of ISAF made better efficiency than that of HAF. 3. Carbon black was more efficient to SBR than to CB. 4. For the aging ratio, the compounding rubber of NR was the highest, and the ratio was decreased in order of the compounding rubber of oil-extended SBR or CB polymer only, the compounding rubber of non oil-extended SBR or CB polymer only, and the blending rubber.

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Studies on it's Practical Application to Auto Pneumatic Tyre and Manufacture of CBR (Part 2.) On the Blend of Diene Rubber and SBR (CBR의 제조(製造) 및 이를 자동차(自動車) tyre에 활용(活用)하는데 관(關)한 연구(硏究) (제2보(第二報)) Diene rubber와 SBR와의 blend에 관(關)하여)

  • Lee, Hyan-O;Lee, Young-Kil
    • Elastomers and Composites
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    • v.6 no.2
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    • pp.47-63
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    • 1971
  • We have studied the blending effects of Diene 33R and styrenebutadiene rubber at various blending ratios of 100/0, 70/30, 50/50, 30/70, 0/100, and of carbon black HAF and ISAF at various compounding ratios of 55 PHR, 65 PHR, 75 PHR for tyre tread rubber. As the results, it was found that ; 1. For tyre tread rubber, when the blending ratio, Diene NF 35R/SBR 1778, indicated 30/70, the physical properties we examined were most excellent. 2. Excellent result was obtained in case of carbon black compounding ratio of 65 PHR. The compounding of ISAF made better result than that of HAF for abrasion quantity, tearing strength, and tensile strength. 3. Heat buildup obtained from compounding carbon black HAF indicated low temperature than that from compounding carbon black ISAF. As the compounding amount of carbon black increased, the heat buildup improved. And as the blending amount of Diene NF 35R decreased, the heat buildup dropped. 4. Carbon black was more efficient to SBR than to Diene Rubber. 5. It is a shortage that elongation revealed low price.

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