• 제목/요약/키워드: compound-K

검색결과 8,272건 처리시간 0.038초

Constituents of the Herb of Isodon excisus var. coreanus

  • Kim, Ho-Kyoung;Whang, Wan-Kyunn;Kim, Il-Hyuk
    • Archives of Pharmacal Research
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    • 제20권3호
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    • pp.291-296
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    • 1997
  • The studies were carried out to evaluate the constituents in the aerial part of Isodon excisus var. coreanus (Labiatae). From the aqueous fraction of methanol extract, compound I (${\alpha}$-[[3-(3, 4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-benzenepropanoic acid), compound II (9-methyl-dihydroferulic acid-4-O-.betha.-D-glucopyranosyl $(1{\rightarrow}2)$-${\alpha}$-L- rhamnopyranosyl (1.rarw.4)-.betha.-D-glucopyranoside), compound III (ent-7.alpha., 11${\alpha}$,15.betha.-trihydroxy-kaur-16-en-1-O-.betha.-D-glucopyranoside) and compound IV ($2{\alpha}$,3${\beta}$,$7{\alpha}$,23-tetrahydroxy-olean-12 -en-28-oic acid 28-O-${\beta}$-D-glucopyranoside) were isolated and identified on the basis of their physicochemical and spectroscopic evidences[IR, FAB(-)MS,$^{1}H-NMR,$$^{13}C-NMR,$$ HMQC$$^{1}H-^{1}H $COSY and HMBC (Heteronuclear Multiple Bond Connectivity)]. Especially, New compounds II and III were named Isodonin A and Isodonin B respectively.

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Al-Ti 혼합 분말 슬러리를 이용한 강의 알루미나이징처리 방법 (Convenient Aluminizing Process of Steel by Using Al-Ti Mixed Powder Slurry)

  • 이영기;김정열;이유기
    • 한국재료학회지
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    • 제19권4호
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    • pp.207-211
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    • 2009
  • In this study, we attempted to develop a convenient aluminizing process, using Al-Ti mixed slurry as an aluminum source, to control the Al content of the aluminized layer as a result of a one-step process and can be widely adopted for coating complex-shaped components. The aluminizing process was carried out by the heat treatment on disc and rod shaped S45C steel substrates with Al-Ti mixed slurries that were composed of various mixed ratios (wt%) of Al and Ti powders. The surface of the resultant aluminized layer was relatively smooth with no obvious cracks. The aluminized layers mainly contain an Fe-Al compound as the bulk phase. However, the Al concentration and the thickness of the aluminized layer gradually decrease as the Ti proportion among Al-Ti mixed slurries increases. It has also been shown that the Al-Ti compound layer, which formed on the substrate during heat treatment, easily separates from the substrate. In addition, the incorporation of Ti into the substrate surface during heat treatment was not observed.

나일론6/이오노머 Semi IPN의 몰드-인-칼라 수지 특성 연구 (Characteristics of Nylon6/Ionomer Semi IPN for Molded-In-Color Compound)

  • 이재훈;황진택;강호종
    • 폴리머
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    • 제36권4호
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    • pp.407-412
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    • 2012
  • Molded-in-color(MIC) 수지로 사용 가능한 나일론6/이오노머 semi interpenetrating network(IPN)의 물성을 기존 MIC 수지인 나일론6/이오노머 블렌드와 비교하여 살펴보았다. 나일론6/이오노머 semi IPN은 분자 수준의 믹싱인 IPN 구조를 가져 블렌드에 비하여 상대적으로 개선된 homogeneous 형태학적 구조를 가짐에 따라 내스크래칭 특성이 개선됨을 알 수 있었다. 이러한 semi IPN 구조는 나일론6의 결정화 속도를 감소시키며 용융점도의 증가 그리고 점도의 온도 의존성을 감소시켜 블렌드에 비하여 상대적으로 MIC용 사출 가공 특성이 우수해짐을 예측할 수 있었다.

The Crystal Structure of Acemetacin Monohrdrate $(C_{21}H_{18}NO_6Cl-H_2O)$, A Non-Steroidal Antiinflammatory Agent

  • Kim, Yang-Bae;Kim, Jeong-Ae;Park, Yeong-Il
    • Archives of Pharmacal Research
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    • 제16권2호
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    • pp.134-139
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    • 1993
  • The molecular structure of acemetacin, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid carboxymethyl ester, was determined by single cystal X-ray diffraction analysis. The compound was recrystallized from a mixture of acetone and water in triclinic, space group P1, with a=7.796(1), b=10.245(2), c=13.542(3)$\AA,\;\alpha=97.35(1),\;\beta=96.34(1),\;\gamma=107.06(1)^\circ$, and Z=2. The calculated density is 1.422; the observed value is $1.42\;g/cm^3$. The structure was solved by the direct method and refined by full matrix least-squares procedure to the final R value of 0,037 for 2960 independent reflections. There are water molecules, which are thought to be co-crystallized during the evaporation procedure, with the ratio of one water per compound molecule in the crystal. The conformation of the compound is found to be very similar to that of indomethacin. The molecules are stabilized by three O-H.....O type intermolecular hydrogen bonds between the oxygen of water molecule and those of the compound.

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규불화염계 복합 조성물을 혼입한 콘크리트의 균열제어 및 내구성 (Durability and Crack Control of Concrete Using Fluosilicates Based Composite)

  • 윤현도;양일승;김도수;길배수;한승구
    • 콘크리트학회논문집
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    • 제18권1호
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    • pp.57-64
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    • 2006
  • 콘크리트에 균열이 발생하면 구조물의 구조적인 결함, 내구성 저하, 외관손상 등을 유발하여 치명적인 손실을 초래하기 때문에 균열제어를 통한 내구성능의 증대가 필수적이다. 국내 콘크리트 구조물의 동향을 살펴보면 LCC개념에 비추어 구조물의 신축비용이 25%에 불과하고, 다양한 형태의 균열보수, 개수, 유지관리 및 폐기처분에 대한 비용이 75%를 차지함에 따라 구조물의 시공시 콘크리트의 균열발생과 시공 후 콘크리트 내 철근부식을 억제하는 기술이 요구된다고 할 수 있다. 본 연구에서는 1990년대 후반부터 인산(H3PO4) 및 불산(HF)을 제조하는 공정 중에 액상형태의 부산물로 회수되는 불화규산(H2SiF6)을 활용하여 안정한 액상형태로 제조되는 규불화염계 화합물에 의한 균열저감 특성과 내구성에 대한 검토를 수행한 결과, 규불화염계 무기 조성물의 첨가로 수밀성이 증진되어 치밀한 경화조직을 형성함으로써 경화 후 급격한 수분의 손실에 따른 경화수축이 억제되어 건조수축을 저감시키는 특성을 발휘하였다. 또한 수화온도 및 수축 저감에 의해 조기에 균열발생을 억제하고, 수밀성을 증진시킴으로써 중성화, 동결융해저항성 및 염소이온침투깊이에 있어서 무첨가 콘크리트에 비해 상당히 개선되는 효과를 확인하였다. 마지막으로, 콘크리트 변형이 크게 발생되는 복합열화 환경 하에서도 SWP-2에 의한 내구성 향상 효과가 확인되었다.

Studies on the anti-parasitic efficacy and safety of ivermectin and pyrantel pamoate compound against Dirofilaria immitis in dogs

  • Youn, Heejeong;Ra, Jeong-Chan;Kim, Byung-Ki;Lim, Yong-Suk;Kim, Kyong-Hee;Lee, Kyong-Eun
    • 대한수의학회지
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    • 제52권1호
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    • pp.53-56
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    • 2012
  • Dirofilaria (D.) immitis is an important canine parasitic nematode in dogs. D. immitis parasitizes the right ventricle and pulmonary artery of dogs. An ivermectin and pyrantel pamoate compound (IPPC) was administered to dogs naturally infected with this parasite. IPPC is composed of 68.0, 136.0 and $272.0{\mu}g$ of ivermectin and 57.0, 114.0 and 227.0 mg pyrantel pamoate for small, middle, and large animals. Ivermectin has activity against nematodes and ectoparasites in dogs. Pyrantel pamoate is also effective against nematodes in dogs. Our results showed that this drug combination has good efficacy in D. immitis infected dogs.

비만세포 매개 즉시형 알레르기 반응에 대한 연명초의 억제 효과 (Inhibitory Effect of Isodon japonicus Hara on Mast Cell-Mediated Immediate-Type Allergic Reactions)

  • 김성화;김대근;채병숙;신태용
    • 생약학회지
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    • 제34권2호통권133호
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    • pp.132-137
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    • 2003
  • The effect of aqueous extract of Isodon japonicus Hara (Labiatae) (IJAE) on mast cell-mediated immediate-type allergic reactions was investigated. IJAE inhibited compound 48/80-induced systemic anaphylaxis and immunoglobulin E (IgE)-mediated local anaphylaxis. When IJAE was pretreated at the same concentration with systemic anaphylaxis, serum histamine levels were reduced in a dose-dependent manner. IJAE dose-dependently inhibited histamine release from rat peritoneal mast cells (RPMC) activated by compound 48/80. The level of cAMP in human mast cell line (HMC-1) cells, when IJAE was added, significantly was increased, compared with that of normal control. These results indicate that IJAE will beneficial in the treatment of immediate-type allergic reaction.

전자기력을 이용한 Al scrap으로 부터 과공정 Al-Si합금의 제조 (Manufacturing Al-scrap into Hypereutectic Al-Si Alloy by Using Electromagnetic Force)

  • 윤지현;문광호;김용현;이광학
    • 한국주조공학회지
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    • 제21권6호
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    • pp.328-335
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    • 2001
  • The objective of this study is to investigate on manufacturing Al-scrap into hypereutectic Al-Si alloy by using electromagnetic force. The Fe element in the aluminium scrap was controlled by intermetallic compound method and using EMF(electromagnetic force). The most lumped compound was found after 10min holding at $690^{\circ}C$. A number of segregated compound was revealed when imposed to EMF at 30A. The refinement of primary Si particles was achieved by EMF stirring. Primary Si particles were refined and spheroidized most of all with the magnetic intensity of 180G for 10 min.

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생약의 아나필락시 반응의 억제 효과 (Inhibitory Effects of Medicinal Plants on Anaphylactic Reaction)

  • 이재관;염정열;김윤철;신태용
    • 약학회지
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    • 제44권6호
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    • pp.489-493
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    • 2000
  • Mortality test has been utilized as a basic method for systemic anaphylactic reaction. Compound 48/80 has been used as a direct and convenient reagent to study the mechanism of anaphylacic reaction. The aqueous extracts of 102 medicinal plants were screened for mortality test using compound 48/80. Sixteen out of the 102 medicinal plants exhibited more than 50% of inhibition on mortality test by their total aqueous extracts with 0.1 mg/g as a final concentration.

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Compound CVT with K-H-V Differential Gear and V-belt Drive

  • Kim, Yeon-Su;Choi, Sang-Hoon
    • International Journal of Precision Engineering and Manufacturing
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    • 제6권1호
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    • pp.5-14
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    • 2005
  • Continuously variable transmission (CVT) mechanisms combine the functions of a K-H-V type differential gear unit and a V-belt type continuously variable unit (CVU). For the 24 different mechanisms, 12 of them are power circulation modes while the other 12 are power split modes. Some useful theoretical formulas related to speed ratio, power flow and efficiency were derived and analyzed. These mechanisms have many advantages: they decrease CVT size and weight, increase overall efficiency, extend speed ratio range, and generate geared neutral. Compound CVTs were developed by combining the power circulation mode and power split mode, which can offer backward motion, geared neutral, underdrive and overdrive.