• Journal of IKEEE
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• v.22 no.4
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• pp.1140-1146
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• 2018

Recently, a methodology for analyzing complex bio-signals using a deep learning model has emerged among studies that recognize human emotions. At this time, the accuracy of emotion classification may be changed depending on the evaluation method and reliability depending on the kind of data to be learned. In the case of biological signals, the reliability of data is determined according to the noise ratio, so that the noise detection method is as important as that. Also, according to the methodology for defining emotions, appropriate emotional evaluation methods will be needed. In this paper, we propose a wavelet -based noise threshold setting algorithm for verifying the reliability of data for multimodal bio-signal data labeled Valence and Arousal and a method for improving the emotion recognition rate by weighting the evaluation data. After extracting the wavelet component of the signal using the wavelet transform, the distortion and kurtosis of the component are obtained, the noise is detected at the threshold calculated by the hampel identifier, and the training data is selected considering the noise ratio of the original signal. In addition, weighting is applied to the overall evaluation of the emotion recognition rate using the euclidean distance from the median value of the Valence-Arousal plane when classifying emotional data. To verify the proposed algorithm, we use ASCERTAIN data set to observe the degree of emotion recognition rate improvement.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.2
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• pp.307-313
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• 2022

As the development of renewable energy expands internationally to cope with global warming and climate change, the share of wind power generation has been gradually increasing. Although wind farms can produce electric power for 24 h a day compared to solar power plants, Their interfere with the operation of nearby radars or communication equipment must be analyzed because large-scale wind power turbines are installed. This study analyzed whether a land radio station can receive sufficient signals when a ship sailing outside the offshore wind farm transmits distress signals on the VHF band. Based on the geographic information system digital map around the target area, wind turbine CAD model, and wind farm layout, the area of interest and wind farm were modeled to enable numerical analysis. Among the high frequency analysis techniques suitable for radio wave analysis in a wide area, a dedicated program applying physical optics (PO) and shooting and bouncing ray (SBR) techniques were used. Consequently, the land radio station could receive the electromagnetic field above the threshold of the VHF receiver when a ship outside the offshore wind farm transmitted a distress communication signal. When the line of sight between the ships and the land station are completely blocked, the strength of the received field decreases, but it is still above the threshold. Hence, although a wind farm is a huge complex, a land station can receive the electromagnetic field from the ship's VHF transmitter because the wave length of the VHF band is sufficiently long to have effects such as diffraction or reflection.

• The Journal of the Acoustical Society of Korea
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• v.27 no.3
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• pp.140-148
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• 2008

In this study, a numerical method for a time-domain acoustic wave backscattering analysis is established based on a physical optics and a Fourier transform. The frequency responses of underwater targets are calculated based on physical optics derived from the Kirchhoff-Helmholtz integral equation by applying Kirchhoff approximation and the time-domain signals are simulated taking inverse fast Fourier transform to the obtained frequency responses. Particularly, the adaptive triangular beam method is introduced to calculate the areas impinged directly by acoustic incident wave and the virtual surface concept is adopted to consider the multiple reflection effect. The numerical analysis result for an acoustic plane wave field incident normally upon a square flat plate is coincident with the result by the analytic time-domain physical optics derived theoretically from a conventional physical optics. The numerical simulation result for a hemi-spherical end-capped cylinder model is compared with the measurement result, so that it is recognized that the presented method is valid when the specular reflection effect is predominant, but, for small targets, gives errors due to higher order scattering components. The numerical analysis of an idealized submarine shows that the established method is effectively applicable to large and complex-shaped underwater targets.

• Journal of Life Science
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• v.14 no.5
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• pp.752-760
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• 2004

The function of the [4Fe-4S] cluster containing iron (Fe-) protein in nitrogenase catalysis is to serve as the nucleotide-dependent electron donor to the MoFe protein which contains the sites for substrate binding and reduction. The ability of the Fe protein to function in this manner is dependent on its ability to adopt the appropriate conformation for productive interaction with the MoFe protein and on its ability to change redox potentials to provide the driving force required for electron transfer. The MgADP-bound (or off) conformational state of the nitrogenase Fe protein structure described reveals mechanisms for long-range communication from the nucleotide-binding sites to control affinity of association with the MoFe protein component. Two pathways, termed switches I and II, appear to be integral to this nucleotide signal transduction mechanism. In addition, the structure of the MgADP bound Fe protein provides the basis for the changes in the biophysical properties of the [4Fe-4S] observed when Fe protein binds nucleotides. The structures of the nitrogenase Fe protein with defined amino acid substitutions in the nucleotide dependent signal transduction pathways of the Switch I and Switch II have been determined by X-ray diffraction methods. These two pathways have been also implicated by site directed mutagenesis studies, structural analysis and analogies to other proteins that utilize similar nucleotide dependent signal transduction pathways. We have examined the validity of the assignment of these pathways in linking the signals generated by MgATP binding and hydrolysis to macromolecular complex formation and intermolecular electron transfer. The results provide a structural basis for the observed biophysical and biochemical properties of the Fe protein variants and interactions within the nitrogenase Fe protein-MoFe protein complex.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.5
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• pp.638-645
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• 2013

Interferon-tau (IFNT) is thought to be the conceptus protein that signals maternal recognition of pregnancy in ruminants. We and others have observed that OCT4 expression persists in the trophectoderm of ruminants; thus, both CDX2 and OCT4 coexist during the early stages of conceptus development. The aim of this study was to examine the effect of CDX2 and OCT4 on IFNT gene transcription when evaluated with other transcription factors. Human choriocarcinoma JEG-3 cells were cotransfected with an ovine IFNT (-654-bp)-luciferase reporter (-654-IFNT-Luc) construct and several transcription factor expression plasmids. Cotransfection of the reporter construct with Cdx2, Ets2 and Jun increased transcription of -654-IFNT-Luc by about 12-fold compared with transfection of the construct alone. When cells were initially transfected with Oct4 (0 h) followed by transfection with Cdx2, Ets2 and/or Jun 24 h later, the expression of -654-IFNT-Luc was reduced to control levels. OCT4 also inhibited the stimulatory activity of CDX2 alone, but not when CDX2 was combined with JUN and/or ETS2. Thus, when combined with the other transcription factors, OCT4 exhibited little inhibitory activity towards CDX2. An inhibitor of the transcriptional coactivator CREB binding protein (CREBBP), 12S E1A, reduced CDX2/ETS2/JUN stimulated -654-IFNT-Luc expression by about 40%, indicating that the formation of an appropriate transcription factor complex is required for maximum expression. In conclusion, the presence of OCT4 may initially minimize IFNT expression; however, as elongation proceeds, the increasing expression of CDX2 and formation of the transcription complex leads to greatly increased IFNT expression, resulting in pregnancy establishment in ruminants.

• Journal of the Korean Society for Nondestructive Testing
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• v.35 no.4
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• pp.268-274
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• 2015

Weld overlay was first used in power plants in the US in the early 1980s as an interim method of repairing the welds of flawed piping joints. Weld overlaid piping joints in nuclear power plants must be examined periodically using ultrasonic examination technology. Portable phased array ultrasonic technology has recently become available. Currently, the application of preemptive weld overlays as a mitigation technique and/as a method to improve the examination surface condition for more complex configurations is becoming more common. These complex geometries may require several focused conventional transducers for adequate inspection of the overlay, the original weld, and the base material. Alternatively, Phased array ultrasonic probes can be used to generate several inspection angles simultaneously at various focal depths to provide better and faster coverage than that possible by conventional methods. Thus, this technology can increase the speed of examinations, save costs, and reduce radiation exposure. In this paper, we explain the general sequence of the inspection of weld overlay and the results of signal analysis for some PAUT (phased array ultrasonic testing) signals detected in on-site inspections.

• Journal of the Korean Society for Nondestructive Testing
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• v.30 no.1
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• pp.6-12
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• 2010

Fiber optic sensor using fiber Bragg grating(FBG) probes is used for monitoring strain and temperature distributed on the wide surfaces of large structures. In this paper, in order to use many FBG probes in one optical fiber line, we propose a complex multiplexing technology which is composed of two techniques, one is time division multiplexing and another is wavelength division multiplexing. However, we only investigate the characteristics of time division multiplexing because FBG sensors basically can be operated by wavelength division multiplexing. We calculate the optimal reflectivities and the lengthwise location of five FBG probes in serial connection in order to obtain the unique reflected intensities from the FBG probes. We fabricate five FBG probes with the reflectivities of 13%, 16%, 25%, 40% and 80%, which are determined by the theoretical calculation, and observe the signal reflected from each FBG in the time domain from the experiment. There are differences between experimental and theoretical results caused by the signal noise and the differences of reflectivities of FBG probes. But the experimental results shows the reflected signals of five FBG probes which prove the availability of complex multiplexing.

• Journal of Genetic Medicine
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• v.14 no.1
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• pp.8-17
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• 2017

Purpose: Pulse wave velocity (PWV) is an indicator of arterial stiffness, and is considered a marker of vascular damage. However, a genome-wide association study analyzing single nucleotide polymorphisms (SNPs) associated with brachial-ankle PWV (baPWV) has not been conducted in healthy populations. We performed this study to identify SNPs associated with baPWV in healthy populations in Korea. Materials and Methods: Genomic SNPs data for 2,407 individuals from three sites were analyzed as part of the Korean Genomic Epidemiologic Study. Without replication samples, we performed multivariable analysis as a post hoc analysis to verify the findings in site adjusted analysis. Healthy subjects aged between 40 and 70 years without self-reported history or diagnosis of hypertension, diabetes, hyperlipidemia, heart disease, cerebrovascular disease and cancer were included. We excluded subjects with a creatinine level >1.4 mg/dL (men) and 1.2 mg/dL (women). Results: In the site-adjusted association analysis, significant associations (P<$5{\times}10^{-8}$) with baPWV were detected for only 5 SNPs with low minor allele frequency. In multivariable analysis adjusted by age, sex, height, body mass index, mean arterial pressure, site, smoking, alcohol, and exercise, 11 SNPs were found to be associated (P<$5{\times}10^{-8}$) with baPWV. The 5 SNPs (P<$5{\times}10^{-8}$) linked to three genes (OPCML, PRR35 and RAB40C) were common between site-adjusted analysis and multivariable analysis. However, meta-analysis of the result from three sites for the 11 SNPs showed no significant associations. Conclusion: Using the recent standard for genome-wide association study, we did not find any evidence of significant association signals with baPWV.

• Journal of IKEEE
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• v.13 no.1
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• pp.77-86
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• 2009

A wavelet Electrocardiogram(ECG) detector and its analog-to-digital converter(ADC) for low-power implantable cardiac pacemakers are presented in this paper. The proposed wavelet-based ECG detector consists of a wavelet decomposer with wavelet filter banks, a QRS complex detector of hypothesis testing with wavelet-demodulated ECG signals, and a noise detector with zero-crossing points. To achieve high-detection performance with low-power consumption, the multi-scaled product algorithm and soft-threshold algorithm are efficiently exploited. To further reduce the power dissipation, a low-power ADC, which is based on a Successive Approximation Register(SAR) architecture with an on/off-time controlled comparator and passive sample and hold, is also presented. Our algorithmic and architectural level approaches are implemented and fabricated in standard $0.35{\mu}m$ CMOS technology. The testchip shows a good detection accuracy of 99.32% and very low-power consumption of $19.02{\mu}W$ with 3-V supply voltage.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.165-171
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• 2011

A Consider the dead man's switch installed in each and every locomotive cab, which support operational safety on railways around the world. The concept is very simple - every 150 to 180 seconds an illuminated push-button demands to be acknowledged so as to know that the Train Driver is alive and active. In the absence of a response over a period of minutes, the vigilance control will automatically apply the train brakes and bring the train to a stand. If we multiply the resetting of the vigilance control 60 times per hour by a 10-hour shift it equals 600 presses of the button during the shift that a Train Driver must pay attention to and acknowledge. This adds a fair bit of pressure on the train driver's job, particularly when he/she is driving through stations, with passengers moving about on platforms in an environment of complex signaling arrangements - all the while looking out for restricting signals. From this perspective, the Vigilance System's demand to be acknowledged every 150/180 seconds is disturbing and can unnecessarily take a driver's attention away from what is happening outside the confines of the cab. A much more dramatic situation can happen when a train driver is driving hour after hour at night when, by Mother's Nature request - people need to sleep. Experience and research shows that the the dead man's switch can be pressed by train driver in a state of deep relaxation and 'micro-sleep'. The vigilance control system which is applied to reduce the drive load considering bio-response multiple unit train is proposed.