• Asian Pacific Journal of Cancer Prevention
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• 제15권19호
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• pp.8007-8018
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• 2014

Cervical cancer is the most common gynecologic malignancy worldwide and development of new therapeutic strategies and anticancer agents is an urgent priority. Plants have remained an important source in the search for novel cytotoxic compounds and several polyphenolic flavonoids possess antitumor properties. In this review article, data about potential anticarcinogenic activity of common natural flavonoids on various human cervical cancer cell lines are compiled and analyzed showing perspectives for the use of these secondary metabolites in the treatment of cervical carcinoma as well as in the development of novel chemotherapeutic drugs. Such anticancer effects of flavonoids seem to differentially depend on the cellular type and origin of cervical carcinoma creating possibilities for specific targeting in the future. Besides the cytotoxic activity per se, several flavonoids can also contribute to the increase in efficacy of conventional therapies rendering tumor cells more sensitive to standard chemotherapeutics and irradiation. Although the current knowledge is still rather scarce and further studies are certainly needed, it is clear that natural flavonoids may have a great potential to benefit cervical cancer patients.

• 가정과삶의질연구
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• 제22권3호
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• pp.1-9
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• 2004

The purposes of this study were (a) to compare the level of sense of community and community activity of the mixed-use residential buildings' residents with the expected residents for the mixed-use residential building, (b) and to investigate the degree of their needs of social interaction. For the survey the questionnaire from 176 residents of mixes-use residential building in Seoul, and 67 expected residents in Bundang Newtown are used. The analytical methods adopted in this study were frequency, percentage, chi-square test and t-test. It was found that the level of sense of community and the community activities of the mixed-use residential building' residents were higher than those of the expected residents. Their residents reported higher degree of participation on community activities than the expected residents. It was also found that the common space in their residential area promoted the residents' sense of community and community activity.

• 한국주거학회논문집
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• 제18권1호
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• pp.131-139
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• 2007

The aim of this paper is to find out different preference of common spaces and shared activities in senior cohousing community between regions in Korea: Seoul and other cities. Social survey was conducted nationwide and the respondents were 50s only, since they are the generation who will face to elderly housing subject within 10 years in turbulent Korean society. Collected data, about 1000, were analyzed by SPSS program using frequency, percentage, and Chi-square test. In summary, respondents mostly would like to move to senior cohousing on circumstance when they remain alone without big difference between regions. Loneliness and housekeeping were considered as the most difficult issues for the elderly to manage by themselves. Among common spaces, exercise room was the most preferred space to meeting room and kitchen. Exercise room was more preferred in Seoul than in other cities, on the contrary meeting room was evidently less preferred in other cities than in Seoul. Regarding shared activities, resident meeting, gardening, and common meal were revealed as less preferred activities than hobby exercise and tea meeting. As a conclusion, I would like to propose that a big common living room is better to be designed for meeting room cum dining and gathering room with flexibility in order to give residents chances to know each other more often. And since common space and shared activity show different preferences by regions, those are to be designed and planned reflecting region's different circumstance.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제34권1호
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• pp.83-89
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• 2008

Purpose: Different patterns in the causes of maxillofacial injury are thought to correlate with socioeconomic status and regional environment. This study investigated maxillofacial fractures in order to analyze maxillofacial trauma characteristics and the relationship between the causes and injury patterns in Korea. Material and methods: A total of 518 patients with maxillofacial fractures who were treated at the Seoul National University Boramae Hospital between 1996 and 2004 were retrospectively analyzed. Data were obtained from the patients' medical records and radiographs. The male to female ratio in the patient group was 2.78:1, and the mean age was 32.3 years. Results: Midfacial fractures were the most common location of injury (46.1%). The most common etiologic factor was an activity associated with daily life (42.6%) including falls, stumbling, and collisions. The second most common cause was assault (32.4%), followed by traffic accidents (13.7%). In the case of midfacial fractures and mandibular fractures, assault was the most common etiologic factor, whereas in the case of alveolar bone fractures, activities associated with daily life were the most common cause. With regard to age groups, assault was the most common cause for patients between 10 and 39 years old and an activity associated with daily life was the most common cause in those under 10 years and over 40 years. Conclusions: This study concluded that activities associated with daily life and assault causes a large proportion of Korean maxillofacial injuries and that preventive measures should be implemented in order to minimize these risks.

• 농업과학연구
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• 제11권2호
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• pp.190-193
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• 1984

쇠비름즙액(汁液)(원액(原液))은 사과 부란병균(病菌)(Valsa mali), 배 검은무늬병균(病菌)(Alternaria kikuchiana), 벼 도열병균(病菌)(Pyricularia oryzae)등 몇가지 식물병원균(植物病原菌)에 대한 항균작용(抗菌作用)을 지니고 있다. 이와 같은 항균작용(抗菌作用)을 나타내는 물질(物質)은 메타놀에 잘 용해(溶解)되며 지질(脂質)에 속하는 물질(物質)로 추정(推定)된다. 그리고 쇠비름즙액(汁液)에 함유(含有)되어 있는 항균물질(抗菌物質)은 균채신장억제(菌采伸長抑制) 뿐만 아니라 포자발아억제(胞子發芽抑制) 효과(效果)를 보여주고 있다.

• 한국멀티미디어학회논문지
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• 제20권8호
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• pp.1421-1429
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• 2017

Human activity recognition has been studied using various sensors and algorithms. Human activity recognition can be divided into sensor based and vision based on the method. In this paper, we proposed an activity recognition system using acceleration sensor and gyroscope sensor in smartphone among sensor based methods. We used Deep Belief Network (DBN), which is one of the most popular deep learning methods, to improve an accuracy of human activity recognition. DBN uses the entire input set as a common input. However, because of the characteristics of different time window depending on the type of human activity, the RBMs, which is a component of DBN, are configured hierarchically by combining them from different time windows. As a result of applying to real data, The proposed human activity recognition system showed stable precision.

• 한국미생물·생명공학회지
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• 제27권5호
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• pp.354-358
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• 1999

In order to know the antifungal characteristics of saturated fatty acids having 6 to 12 carbons, their minimum inhibitory concentrations (MICs) and minimum fungicidal concentrations (MFCs) were estimated against Saccharomyces cerevisiae. Fatty acids from C6 to C11 exhibited increasing activity with chain length, but C12 fatty acid did not show activity at all. In relation to antifungal modes of actions, fatty acids investigated showed on inhibitory activity toward the plasma membrane H+-ATPase of Saccharomyces cerevisiae. Their inhibitions to the glucose-induced acidification and ATP hydrolysis caused by the proton pump were found to be in common wiht antifungal activities. At the test concentration of 1mM, hexanoic acid (C6) showed the lowest inhibition of about 30%, while undecanoic acid(C11) showed the strongest inhibition of over 90%. In addition, as seen with antifungal activity, the inhibitory activity of dodecanoic acid (C12) was suddenly reduced to less than 50%.

• 한국의사학회지
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• 제20권2호
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• pp.42-49
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• 2007

'confucian doctor' are typically people who study the principles of medicine based on Confusional concepts. In Korea, studying both medicine and Confucianism became a common practice since Confucianism became popular and the class of intellectuals were formed around Confucianism. This study is a research on the activity of confucian doctors in Korea. Many confucian doctors that were discovered in documents are organized according to their activity and books they wrote.

• BMB Reports
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• 제32권4호
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• pp.331-338
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• 1999

Ethanol catabolism is thought to produce metabolic disorders resulting in alcoholic liver disease. To investigate the mutual effects of ethanol catabolism and cholestasis induced by common bile duct ligation on the activities of carboxylesterase, we have determined the enzyme activities in rat hepatic (cytosolic, mitochondrial, and microsomal) preparations as well as in rat serum using ten animal models: normal rats (group 1), sham-operated rats (group 2), common bile duct-ligated rats (group 3), ethanol-intoxicated rats (group 4), sham-operation plus chronic ethanol-intoxicated rats (group 5), common bile duct-ligated plus chronic ethanol-intoxicated rats at 1.5h and 24h (groups 7A and 7B), and duct-ligated and acute ethanol intoxicated rats at 1.5 h and 24 h (groups 8A and 8B). The $K_m$ and $V_{max}$ values of carboxylesterase from these hepatic preparations of cholestatic rat liver combined with chronic ethanol intoxication were also measured by using ethyl valerate as the substrate from the 14th day post-ligation. Carboxylesterase activities of all hepatic preparations and rat serum (group 3) showed significant decreases compared to the activities from the sham-operated control (group 2). Enzyme kinetic parameters indicated that $V_{max}$ of carboxylesterase from all the hepatic preparations in cholestatic rats (group 3) decreased significantly, although the $K_m$ values were about the same as in the sham-operated control (group 2). When cholestasis was combined with chronic ethanol intoxication (group 6), carboxylesterase activities showed further decrease in all the hepatic preparations and serum compared to the control activity (group 5). The $V_{max}$ also decreased significantly, although $K_m$ values did not change. When common bile duct ligation was combined with acute ethanol intoxication (group 8), the enzyme activities in the rat liver and serum showed significant decrease compared to the activity from acute ethanol-intoxicated rats (group 7). However, quite contrary to this, the activities of serum from acute ethanol intoxication 1.5 h (group 7A) increased significantly compared to the activities in the normal control (group 1). These results, therefore, suggest that the biosynthesis of hepatic carboxyl-esterase seems to decrease when cholestasis is combined with chronic and acute ethanol intoxication, and the decrease in activity is more significant than from cholestasis alone.

• 한국응용과학기술학회지
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• 제39권2호
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• pp.246-260
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• 2022

이 연구는 초등학교 3, 4학년 체육교과서 무용 활동의 창의성 교육 내용을 분석하기위해 수행되었다. 이를 위하여 초등학교 3, 4학년 체육과 검정교과서 16종과 보조자료를 수집하였으며 4P 모형에 기반한 체육교과서 창의성 교육 내용분석틀을 활용하여 분석하였다. 연구의 진실성을 확보하기 위하여 전문가협의를 운영하였다. 이에 따른 연구결과는 다음과 같다. 첫째, 창의적 사람 관점에서 창의적 심성에서는 '탐구심'이 가장 많았으며 나머지 요소들은 비교적 골고루 나타났다. 활동 주체는 '개인'과 '동료(팀)'가 비슷한 빈도를 보였다. 둘째, 창의적 과정 관점에서 활동 영역은 모두 '학습'으로 나타났고 활동 목적은 대부분의 요소들이 골고루 나타났으며 창의적 과정이 활용되는 모습이 탐색되었다. 셋째, 창의적 산출물 관점에서 활동 방식은 신체활동수행이 가장 많이 나타났으며 2~3개의 활동 방식이 함께 쓰이고 있었다. 창의성 요소는 모든 요소가 골고루 나타난 가운데 민감성과 정교성이 4개로 가장 많았다. 넷째, 창의적 환경 관점에서 활동 공간은 제약 없음이 대부분이었으며 활동 매체는 신체를 활용한 교육 내용이 많았다. 이 연구를 통하여 무용 활동의 창의성 교육이 양적으로 확대되고 질적으로 심화되어야 함이 요구되었고 무용 활동의 창의성 교육 내용이 타영역으로 확산되어야 할 필요성이 탐색되었다.