• Polymer(Korea)
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• v.31 no.2
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• pp.153-159
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• 2007

Biodegradable molecularly imprinted polymers (MIPs) can be applied in the biomedical area of biosensors, drug delivery, etc. Therefore, in this study, biodegradable theophylline MIPs were synthesized via photopolymerization using a poly $(\varepsilon-caprolactone)$ (PCL) macromer as a cross-linker and their physical properties were investigated. The yield for the synthesis of the PCL macromer with terminal acrylate groups was ca. 78 mol%. The products were characterized by the combination of FT-IR and $^1H-NMR$ spectroscopic analyses. UV/Visible spectroscopic analysis for removing and rebinding theophylline was performed by monitoring the theophylline concentration in the solution. In vitro biodegradation tests of the theophylline MIPs performed in phosphate buffered saline (PBS) solution at $37^{\circ}C$ showed good biodegradability of the MIPs.

• Journal of the Korean Wood Science and Technology
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• v.43 no.2
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• pp.156-167
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• 2015

The aim of this study was to determine the physical and mechanical properties of glued laminated timber (glulam) manufactured from small-diameter logs of three wood species, Acacia mangium (mangium), Maesopsis eminii (manii), and Falcataria moluccana (sengon), with densities of 533, 392, and $271kg/m^3$, respectively. Glulam measuring 5 cm by 7 cm by 160 cm in thickness, width, and length, respectively, was made with three to five lamina, or layers, and isocyanate adhesive. The glulams contained either the same wood species for all layers or a combination of mangium face and back layers with a core layer of manii or sengon. Solid wood samples of the same size for all three species were included as a basis for comparison. Physical-mechanical properties and delamination tests of glulam referred to JAS 234:2003. The results showed that the properties of same species glulam did not differ from those of solid wood, with the exception of the shear strength of glulam being lower than that of solid wood. Wood species affected glulam properties, but three- and five-layer glulams were not different except for the modulus of elasticity. All glulams were resistant to delamination by immersion in both cold and boiling water. The glulams that successfully met the JAS standard were three- and five-layer mangium, five-layer manii, and five-layer mangium-manii glulams.

• Tribology and Lubricants
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• v.31 no.2
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• pp.35-41
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• 2015

A water-pump located in the cooling area of a car circulates cooling water. A particular bearing element, known as a water-pump bearing, installed in the rotating part carries the entire load. The failure of this water-pump bearing has a direct impact on the failure of the automobile engine, and so securing its reliability is crucial. Several researchers have examined the design principles of the water-pump bearing, but there are no reports on the life characteristic of the bearing yet. Herein, we report the construction of test equipment to reproduce the spalling of the roller contact, which is the main failure mode of the chosen water-pump bearing. We chose the radial load as an accelerated stress factor and validated the failure mode by monitoring the surface defects. We conducted the accelerated life test after determining the accelerated stress level through a combination of finite element analysis and a preliminary test. In the life tests, we used an accelerometer to perform failure diagnosis. In the last stage of this study, we present a statistical reliability analysis. Thus, we fully estimated the shape parameter of the water-pump bearing, accelerating level on the load , and the lifetime (MTTF and B₁₀ life) under real use conditions, and finally proposed an interval estimation value considering the uncertainty of the estimated value.

• Proceedings of the Korean Society of Plant Pathology Conference
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• 1994.06a
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• pp.27-49
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• 1994

Root colonization of biocontrol agents via seed treatment was investigated and a compatible combination, Gliocladium virens G872B and Pseudomonas putida Pf3, in colonizing cucumber rhizosphere was confirmed through the study. Much higher number of fungal and bacterial propagules were detected when two isolates were inoculated together. The presence of Pf3 in root system was greatly helpful to G872B to colonize at root tip. The mechanism of this phenomenon is partially elucidated through the results of in vitro experiments and the observations of scanning electron and fluorescence microscope. Addition of Pf3 cells resulted earlier germination of G872B conidia and increased mycelial growth. And the more number of germinated conidia on seed coat, the more vigorous hypal streching and sporulation on the root surface were observed in coinoculated treatment. The propagules of G872B on the cucumber root when they were challenged against the pathogenic Fusarium oxysporum, were even higher than that of G872B treated alone, and the magnitude of such a difference was getting grater toward the root ip and the population of F. oxysporum on the root was reduced by seed inoculation of G872B. The rhizosphere competence was obviously reflected to disease suppression and plant growth promotion that induced by the given isolate. Green house experiments revealed that the combined treatment provided long-term disease suppression with greater rate and the larger amount of fruit yield than single treatments. Through this study the low temperature growing Pseudomonas fluorescens M45 and MC07 were evaluated to apply them to the winter crops in field or plastic film house. In vitro tests reveal that M45 and MC07 inhibited the mycelial growth of Pythium ultimum, Rhizoctona solani and Phytophthora capsici and enhanced growth of cucumber cotyledon in MS agar. This effect was more pronounced when the bacteria were incubated at 14$^{\circ}C$ than at 27$^{\circ}C$. And disease suppression and plant growth promotion in green house were also superior at low temperature condition. Seed treatment of M45 or soil treatment of MC07 brought successful control of damping-off and enhanced seedling growth of cucumber. The combined treatment of two isolates was more effective than any single treatment.

• Journal of KIISE:Software and Applications
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• v.30 no.11
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• pp.1072-1079
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• 2003

This study is purported for suggesting a new clustering algorithm that enables incremental categorization of numerous documents. The suggested algorithm adopts the natures of the spherical k-means algorithm, which clusters a mass amount of high-dimensional documents, and the fuzzy ART(adaptive resonance theory) neural network, which performs clustering incrementally. In short, the suggested algorithm is a combination of the spherical k-means vector space model and concept vector and fuzzy ART vigilance parameter. The new algorithm not only supports incremental clustering and automatically sets the appropriate number of clusters, but also solves the current problems of overfitting caused by outlier and noise. Additionally, concerning the objective function value, which measures the cluster's coherence that is used to evaluate the quality of produced clusters, tests on the CLASSIC3 data set showed that the newly suggested algorithm works better than the spherical k-means by 8.04% in average.

• The KIPS Transactions:PartD
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• v.17D no.6
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• pp.405-414
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• 2010

A rule is defined as a case to determine the target values according to combination of various Business factors. The information system is used to represent enterprise's business, which includes and implements the amount of these rules to Rule-Based System. A Rule-Based System can be constructed by using the rules engine method or Relational Database technology. Because the rules engine method has some disadvantages, the Rule-Based System is mostly developed with Relational Database technology. When business scales become larger and more complex, a large number of various rule cases must be operated in system, and processing these rule cases requires additional time, overhead and storage space, and the speed of execution slows down. To solve these problems, we propose a simplification algorithm that converts a large amount of rule cases to simplification rule cases with same effects. The proposed algorithm is applied to hypothetical business rule data and a large number of simplification experiments and tests are conducted. The final results proved that the number of rows can be reduced to some extent. The proposed algorithm can be used to simplify business rule data for improving performance of the Rule-Based System implemented with the Relational Database.

• Journal of the Korean Society of Propulsion Engineers
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• v.21 no.1
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• pp.36-43
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• 2017

In this study, a pintle injector rocket engine which uses kerosene and liquid oxygen as propellants was manufactured by collecting basic design data and establishing a design procedure. Combustion performance of the liquid rocket engine was investigated by characteristic velocity efficiency with characteristic length of the combustion chamber and total momentum ratio. As a result of hot fire tests, it showed that the engine had shorter characteristic length comparing to those of other type injectors, which was known as recommended value with the propellant combination. Also, the characteristic velocity efficiency was greatly affected by total momentum ratio and almost constant within 1.0~1.5.

• Clinical and Experimental Pediatrics
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• v.64 no.8
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• pp.373-383
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• 2021

Rhinitis is among the most common respiratory diseases in children. Nonallergic rhinitis, which involves nasal symptoms without evidence of systemic allergic inflammation or infection, is a heterogeneous entity with diverse manifestations and intensities. Nonallergic rhinitis accounts for 16%-89% of the chronic rhinitis cases, affecting 1%-50% (median 10%) of the total pediatric population. The clinical course of nonallergic rhinitis is generally rather mild and less likely to be associated with allergic comorbidities than allergic rhinitis. Here, we aimed to estimate the rate of coexisting comorbidities of nonallergic rhinitis. Nonallergic rhinitis is more prevalent during the first 2 years of life; however, its underestimation for children with atopic tendencies is likely due to low positive rates of specific allergic tests during early childhood. Local allergic rhinitis is a recently noted phenotype with rates similar to those in adults (median, 44%; range, 4%-67%), among patients previously diagnosed with nonallergic rhinitis. Idiopathic rhinitis, a subtype of nonallergic rhinitis, has been poorly studied in children, and its rates are known to be lower than those in adults. The prevalence of nonallergic rhinitis with eosinophilia syndrome is even lower. A correlation between nonallergic rhinitis and pollution has been suggested owing to the recent increase in nonallergic rhinitis rates in highly developing regions such as some Asian countries, but many aspects remain unknown. Conventional treatments include antihistamines, intranasal corticosteroids, and recent treatments include combination of intranasal corticosteroids with azelastin or decongestants. Here we review the prevalence, diagnosis, comorbidities, and treatment recommendations for nonallergic rhinitis versus allergic rhinitis in children.

• The Journal of Engineering Geology
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• v.31 no.3
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• pp.269-281
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• 2021

Land creeping is the imperceptibly slow, steady, downward movement o f slope-forming soil or rock. Because creep-related failures occur frequently on a large scale without notice, they can be hazardous to both property and human life. Korea Forest Service has operated the prevention and response system from land creeping which has been on the rise since 2018. We categorized and proposed three survey steps (e.g., preliminary, regional, detailed) for investigation of creeping susceptibility site with a focus on geophysical mapping of a selected test site, Yongheung-dong, Pohang, Korea. The combination of geophysical (dipole-dipole electrical resistivity tomography and reciprocal seismic refraction technique, well-logging), geotechnical studies (standard penetrating test, laboratory tests), field mapping (tension cracks, uplift, fault), and comprehensive interpretation of their results provided the reliable information of the subsurface structures including the failure surface. To further investigate the subsurface structure including the sliding zone, we performed high-resolution geophysical mapping in addition to the regional survey. High-resolution seismic velocity structures are employed for stability analysis because they provided more simplified layers of weathering rock, soft rock, and hard rock. Curved slip plane of the land creeping is effectively delineated with a shape of downslope sliding and upward pushing at the apex of high resistive bedrock in high-resolution electrical resistivity model with clay-mineral contents taken into account. Proposed survey steps and comprehensive interpretation schemes of the results from geological, geophysical, and geotechnical data should be effective for data sets collected in a similar environment to land-creeping susceptibility area.

• Dementia and Neurocognitive Disorders
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• v.17 no.3
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• pp.110-119
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• 2018

Background and Purpose: To analyze $^{18}F-THK5351$ positron emission tomography (PET) scans of patients with clinically diagnosed nonfluent/agrammatic variant primary progressive aphasia (navPPA). Methods: Thirty-one participants, including those with Alzheimer's disease (AD, n=13), navPPA (n=3), and those with normal control (NC, n=15) who completed 3 Tesla magnetic resonance imaging, $^{18}F-THK5351$ PET scans, and detailed neuropsychological tests, were included. Voxel-based and region of interest (ROI)-based analyses were performed to evaluate retention of $^{18}F-THK5351$ in navPPA patients. Results: In ROI-based analysis, patients with navPPA had higher levels of THK retention in the Broca's area, bilateral inferior frontal lobes, bilateral precentral gyri, and bilateral basal ganglia. Patients with navPPA showed higher levels of THK retention in bilateral frontal lobes (mainly left side) compared than NC in voxel-wise analysis. Conclusions: In our study, THK retention in navPPA patients was mainly distributed at the frontal region which was well correlated with functional-radiological distribution of navPPA. Our results suggest that tau PET imaging could be a supportive tool for diagnosis of navPPA in combination with a clinical history.