• Research in Community and Public Health Nursing
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• v.14 no.3
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• pp.432-444
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• 2003

Purpose: This study attempted to verify the effect of Koryo hand therapy on menstrual cramps and dysmenorrhea among college students. Method: This study performed the quasi-experimental design with nonequivalent control group and the pre and post-test design from August 28 to November 4, 2002. The subjects of this experimental study consisted of 64 college students in the nursing college of K University in D city and K college students in K city, who had more than 5.0 GRS score of menstrual cramps. Among them, 16 people belonged to the experimental group A by using Ceramic Seo Am moxa therapy, 16 to the experimental group B by using Seo Am pellet therapy, 16 to the experimental group C by using combination of Ceramic Seo Am moxa therapy and Seo Am pellet therapy and 16 to the control group. Three different kinds of methods were used three times per week for $5{\sim}6$ weeks(a total of $15{\sim}18$ times) interventions were completed. For the experimental group, A Ceramic Seo Am moxa therapy was given for 40 minutes per each treatment; for the experimental group, B Seo Am pellet therapy was given for 4 hours: for the experimental group, C combination of Ceramic Seo Am moxa therapy and Seo Am pellet therapy was given. To measure menstrual cramps, the graphic rating scale (GRS) was used and to measure dysmenorrheal, a dysmenorrhea scale (15 contents) was used, which was modified from Han &Hur's scale (13 contents). Cronbach's was 0.78 in the pre-test, 0.83 in the first post-test, 0.89 in the following post-test. Data were analyzed by one-way ANOVA, 2 test, repeated measures ANOVA, time contrast test and Sheffe test with the SPSS/Win 11.0 program. Results: ? The first hypothesis, 'Among the experimental group A by using Ceramic Seo Am moxa therapy, the experimental group B by using Seo Am pellet therapy and the experimental group C by using combination of Ceramic Seo Am moxa therapy and Seo Am pellet therapy will have different graphic rating scores of menstrual cramps', was supported (F=6.77, p=0.000, Interaction: p=0.000). ? The second hypothesis, 'Among the experimental group A by using Ceramic Seo Am moxa therapy, the experimental group B by using Seo Am pellet therapy, the experimental group C by using combination of Ceramic Seo Am moxa therapy and Seo Am pellet therapy and the control group will have a significantly different level of dysmenorrhea', was supported (F=6.88, p=0.000, Interaction: p=0.000). From the above results, it can be an effective nursing intervention to give Koryo hand therapy to college students who have menstrual cramps and dysmenorrhea. Conclusion: These findings indicate that Koryo hand therapy could be applied to improve the quality of life and to prevent drug misuse among college students who are physically, mentally and psychologically suffering from menstrual cramps and dysmenorrhea. Furthermore, Koryo hand therapy could be developed as an effective Korean alternative and complementary care in the future. and it could also provide a guideline to apply Koryo hand therapy to other pain and difficulties.

• Journal of Veterinary Clinics
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• v.14 no.2
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• pp.215-222
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• 1997

Enrofloxacin-colistin combination, widely used in Gram negative infections in veterinary sector, was investigated in terms of MIC and initial killing rate using E coli k 88ab, Salmonella typhimurium, Pasteurella multocida type A, Bordetella bronchiseptica and Staphylococcus aureus as test organisms. On the basis of MICs of enrofloxacin-colistin combination against the above bacteria, killing rates of the combination of enrofloxacin and colistin at the ratio of 5:0, 4:1, 3:2, 1:1, 2:3, 1:4 and 0:5, indicated high and rapid antibacterial acitivities against all but Staphylococcus aureus R-209, with the number of bacteria reducing to less than one percent within two hours. At the MIC of enrofloxacin or colistin, both antibacterials showed the highest killing rates during 2-4 hours against Gram negatives such as E coli K88ab,Pasteurella multocida type A and Bodetella bronchiseptica but allowed the regrowth of the same pathogens thereafter. On the while, the combination of two antibacterials at a fourth MIC resulted in high killing rate without bacterial regrowth during 24 hours, suggesting the synergistic antivacterial effects. The combination, however, did not show favourable activity against Gram negatime S typhimurium and Gram positive S aureus ergistic antibacterial activity against Gram negatime pathogens but also colistin showed LPS-neutraization, we could suggest the combination should provide clinically positive therapeutic armarium in Gram negative infections.

• Wind and Structures
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• v.31 no.6
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• pp.523-532
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• 2020

As the height and flexibility of high-rise buildings increase, the wind loads become more dominant and the combination coefficient of Equivalent Static Wind Loads (ESWLs) should be considered when they are used in the structural design. In the first phase of the study, a brief introduction to the theory on the combination coefficient for high-rise buildings was given and then the time history of wind-induced responses of a 208-meter high-rise building with an elliptical cross-section was presented based on the wind tunnel test results for pressure measurement. The correlation between wind-induced responses was analyzed and the combination coefficients of ESWLs of the high-rise buildings using Turkstra's rule, and Asami's method, were calculated and compared with related design codes, e.g., AIJ-RLB, ASCE 7-10, and China Load Code for structural design. The results of the study showed that the combination coefficients from Asami's method are conservative compared with the other three methods. The results of this paper would be helpful to the wind-resistant design of high-rise buildings with elliptical cross-section.

• Journal of Korean Society for Quality Management
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• v.17 no.2
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• pp.70-80
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• 1989

A nonparametric test for testing the parallelism of regression lines against ordered alternatives is proposed. The proposed test statistic is based on a linear combination of robust slope estimators. It is a modified version of the Adichie's test statistics based on scores. A snail-sample Monte Carlo study shows that the proposed test is compatible with the Adichie's test.

• Journal of Information Processing Systems
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• v.20 no.3
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• pp.285-295
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• 2024

Driven by the vague assessment big data, a product service system (PSS) evaluation method is developed based on a hybrid model of multi-weight combination and improved TOPSIS by relative entropy. The index values of PSS alternatives are solved by the integration of the stakeholders' vague assessment comments presented in the form of trapezoidal fuzzy numbers. Multi-weight combination method is proposed for index weight solving of PSS evaluation decision-making. An improved TOPSIS by relative entropy (RE) is presented to overcome the shortcomings of traditional TOPSIS and related modified TOPSIS and then PSS alternatives are evaluated. A PSS evaluation case in a printer company is given to test and verify the proposed model. The RE closeness of seven PSS alternatives are 0.3940, 0.5147, 0.7913, 0.3719, 0.2403, 0.4959, and 0.6332 and the one with the highest RE closeness is selected as the best alternative. The results of comparison examples show that the presented model can compensate for the shortcomings of existing traditional methods.

• Journal of Acupuncture Research
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• v.33 no.2
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• pp.135-150
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• 2016

Objectives : The aim of this study is to review the combination effects and adverse effects of Yerba Mate (Ilex paraguariensis) on the treatment of obesity. Methods : Four databases were searched, including Pubmed, National assembly library, RISS4u, and NDSL, for studies published before March 31, 2016 using the keywords 'yerba mate', 'Ilex paraguariensis', and those related to 'obesity'. Clinical trials, and both in vivo and in vitro studies were classified according to the following categories: publication year, nationality, types and composition of test compounds, combination effects, adverse effects, and safety. Results : A total of 16 articles (14 clinical trials, one in vivo, one in vitro) were included in the analysis. Combination effects were reported from six YGD (Yerba Mate, Guarana, Damiana, Zotrim), five Meltdown, one Shred-matrix, one DBX (DymaBurn Xtreme), one XSIII research study, and adverse effects were reported from two YGD (Zotrim), four Meltdown, one Shred-matrix and one MetEF research study. YGD and Shred-matrix increased satiety while YGD and MetEF had adverse gastrointestinal effects potentially due to guarana. Meltdown and Shred-matrix increased energy expenditure and fat oxidation and had the adverse effects of increased heart rate and blood pressure due to the thermogenic effect of caffeine and yohimbine. DBX increased resting energy expenditure but no difference was observed in respiratory exchange ratio. XSIII reduced body weight gain and food intake more than each of the extracts did on their own. Conclusion : Taken together, the combination effects and adverse effects differed according to the composition of test compounds and the ratio of ingredients. Multicomponent approaches should be used for treating multifactorial diseases such as obesity. As a general conclusion, there is a place for a combination of herbal components including yerba mate, based on the principle of Kun-Shin-Choa-Sa for the treatment of obesity.

• Korean Journal of Acupuncture
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• v.35 no.4
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• pp.187-202
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• 2018

Objectives : Non-invasive transcranial electrical stimulation is one of therapeutic interventions to change in neural excitability of the cortex. Transcranial electro-acupuncture (TEA) can modulate brain functions through changes in cortical excitability as a model of non-invasive transcranial electrical stimulation. Some composites of fermented Scutellaria baicalenis (FSB) can activate intercellular signaling pathways for activation of brain-derived neurotrophic factor that is critical for formation of neural plasticity in stroke patients. This study was aimed at evaluation of combinatory treatment of TEA and FSB on behavior recovery and cortical neural excitability in rodent focal stroke model. Methods : Focal ischemic stroke was induced by photothrombotic injury to the motor cortex of adult rats. Application of TEA with 20 Hz and $200{\mu}A$ in combination with daily oral treatment of FBS was given to stroke animals for 3 weeks. Motor recovery was evaluated by rotating bean test and ladder working test. Electrical activity of cortical pyramidal neurons of stroke model was evaluated by using multi-channel extracellular recording technique and thallium autometallography. Results : Compared with control stroke group who did not receive any treatment, Combination of TEA and FSB treatment resulted in more rapid recovery of forelimb movement following focal stroke. This combination treatment also elicited increase in spontaneous firing rate of putative pyramidal neurons. Furthermore expression of metabolic marker for neural excitability was upregulated in peri-infract area under thallium autometallography. Conclusions : These results suggest that combination treatment of TEA and FSB can be a possible remedy for motor recovery in focal stroke.

• Advances in environmental research
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• v.5 no.3
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• pp.201-211
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• 2016

Laboratory tests were conducted to evaluate the performance of waste rubber shreds in leachate collection layer of engineered landfills. The study found that waste rubber shreds layer in combination with a gravel layer can be of potential use in landfill drainage system. To study the performance, conventional gravel along with waste rubber shreds were used in different combinations (with total layer thickness = 500 mm) as leachate collection media. For the laboratory study poly vinyl chloride (PVC) pipes were used. The size range of waste rubber shreds used were 25 mm to 75 mm in length and width = 10 to 20 mm. The gravel size used in the leachate collection media is 10 mm to 20 mm size. Performance study of 7 Test Cols. with different combinations of waste rubber shreds and gravel bed thickness were studied to find out the best combination. The study found that the Test Col.-3 having waste rubber shreds thickness = 200 mm and gravel layer thickness = 300 mm gave the best results in terms of percentage removal in various physicochemical parameters present in the leachate. Further to find the best size rubber shreds three more Test Cols - 8, 9 and 10 were constructed having the rubber shreds and gravel layer ratio same as that of Test Col.-3 but having rubber shreds width = 10 mm, 15 mm and 20 mm respectively. Based on the results obtained using Test Cols. 8, 9 and 10 the study found that smaller size rubber shreds gave bests results in terms of improvement in various leachate parameters.

• Geomechanics and Engineering
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• v.29 no.4
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• pp.407-420
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• 2022

Embedded piles, which are typically used in Korea, are precast piles inserted into prebored ground with cement paste. Dynamic pile tests tend to underestimate the bearing capacity of embedded piles because of the undeveloped shaft resistance prior to the curing of the cement paste and the insufficient energy transferred after the curing. In this study, a resistance combination method using the base resistance before the cement paste is cured and the shaft resistance after the cement paste is cured is proposed to obtain a combined load-settlement curve from dynamic pile tests. Two pairs of embedded piles with diameters of 600 and 500 mm are installed. Each pair comprises one pile for the dynamic pile test and another pile for the static load test. The shape of the load-settlement curve obtained using the proposed method is similar to that obtained from the static load test. Thus, the resistances evaluated using the proposed method at selected settlements are similar to those obtained from the static load test. This study shows that the resistance combination method may be used effectively in dynamic pile tests to accurately evaluate the bearing capacity of embedded piles.

• The Monthly Technology and Standards
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• s.14
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• pp.85-98
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• 2003