• Journal of Pharmaceutical Investigation
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• v.37 no.3
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• pp.187-192
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• 2007

A reversed phase HPLC analysis of atorvastatin (AS) standard solution was performed using diclofenac (DF) as internal standard. Column oven temperature, flow rate and the composition of the mobile phase were varied in order to determine a practical system setup using a C18 column and UV detector. Two C18 columns of different length were compared regarding their influence on the AS peak shape. Based on these preliminary experiments a validation study was performed utilizing a C18 column at $62^{\circ}C$ with a mobile phase consisting of sodium phosphate buffer (0.05 M, pH 4.0), methanol and acetonitrile (40:50:10, v/v/v). The detection limit for AS was $0.1{\mu}g/ml$ and inter- and intra-day calibration curves were linear over a concentration range of $0.2-50{\mu}g/ml$. Accuracy and precision were satisfactory in the AS concentration range of $0.5-50{\mu}g/ml$.

• Proceedings of the Korea Concrete Institute Conference
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• 2005.11a
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• pp.213-216
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• 2005

A numerical analysis was performed for interior connections of continuous flat plate to analyze the effect of design parameters such as column section shape, gravity load and slab span on the behavioral characteristics of the connections. Through the parametric study, the variations of shear stress distribution around the connection were investigated. According to the result of numerical analysis, as the length of the cross section of column in the direction of lateral load increases and gravity load increases, the effective area and the maximum shear strength providing the torsional resistance decrease considerably. And as the slab span loaded with relatively large gravity load increases, the negative moment around the connection increases and therefore the strength of connection against unbalanced moment decreases.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2008.11a
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• pp.129-133
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• 2008

For the construction of Top-Down structures, it is crucial to have a solid connection between prefounded columns and slabs. This paper presents a new construction method for the connection when using a circular Concrete Filled Tube (CFT) as a prefounded column as an alternative to currently using wide flange type columns. The development of shear studded jackets along with a shear band suitable for the circular shape of the column has been made. The details and mechanism of the connection is explained together with the results of experiments which verified the structural integrity of the connection.

• Transactions of the Korean Society of Mechanical Engineers
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• v.11 no.4
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• pp.629-636
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• 1987

An experiment is carried out to study the surface-tension driven flow characteristics in a cylindrical liquid column heated from above (which is the low gravity floating zone simulated on earth) with varing the aspect ratio and diameter of the liquid column. Hexadecane, octadecane, silicon oil(10cs), FC-40 and water are used as the test liquids. The free surface shape varies sinusoidally for Ma>M $a_{cr}$ and its frequency is found to be the same as that of temperature oscillation. It is verified that the surface temperature profile changes from linear to S-shaped profile for Ma>M $a_{cr}$ . The frequency of temperature oscillation decreases with increasing liquid volume, while its level increases. M $a_{cr}$ decreases with increasing aspect ratio, and also decreases with increasing Prandtl number in the range of 25

• Transactions of the Korean Society of Machine Tool Engineers
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• v.17 no.1
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• pp.35-42
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• 2008

By the reason of increased demand of high productivity and quality, the manufacturer have an effort in many directions of a machine tool industries. Among there, we proposed method of decreasing displacement in MC(machining center). In other words, Quality related with vibration of a tool cutting products. For decreasing it, improved by optimizing a shape of the column-part and acceleration curves of motors. In this paper we could find design factors has much influence on decreasing the displacement using the DOE(Design of Experiments) and optimized the level of the factors using $ADAMS^{(R)}$ and $MINITAB.^{(R)}$ And we suggest optimized a acceleration curve using $Matlab^{(R)}$.

• Computers and Concrete
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• v.19 no.4
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• pp.405-411
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• 2017

Carbon Fiber Reinforced Plastic (CFRP) has commonly been used to strengthen existing RC structures. Wrapping the whole component with CFRP is an effective method and simple to execute. Besides, specific configuration of CFRP sheets (L, X and T shape) has also been considered in some experiments to examine CFRP effects in advance. This study aimed to provide an optimal CFRP configuration to effectively retrofit the beam-column connection using continuous material topology optimization procedure. In addition, Moved and Regularized Heaviside Functions and penalization factors were also considered. Furthermore, a multi-material procedure was also used to compare with the results from the single material procedure.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2003.09a
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• pp.163-171
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• 2003

Most of existing beam-to-column connections are reinforced symmetrically because of reverse action cause by earthquake but in the weak-earthquake region like Korea connections reinforced asymmetrically can be used. Specially, the connections between CFT(Concrete Filled Tube) column and H-shape beam can be applied by simplified lower diaphragm. The tensile capacity of Combined Cross Diaphragm for upper reinforcing was tested by simple tension test and four types for lower reinforcing; Combined Cross, None, Horizontal T-bar and Vertical Plate were tested by ANSI/AISC SSPEC 2002 loading program. Horizontal T-bar and stud bolts in vertical flat bar transmit tensile stress from bottom flange of beam to filled concrete. All test specimens were satisfied 0.01 radian of inelastic rotational requirement in ordinary moment frame of AISC seismic provision. As the results of parametric studies, simplified lower diaphragms demonstrated an outstanding strength, stiffness and plastic deformation capacity to use sufficient seismic performance in the field.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2003.09a
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• pp.199-204
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• 2003

The purpose of this study is to experimentally investigate the structural performance of concrete exterior beam-column joints confined by carbon sheet tube. Four specimens were produced with different numbers of carbon sheet and the other specimen was produced with reinforced concrete. A hydraulic dynamic actuator with 30tonf capacity was used to cyclic lateral loading test. The experimental results represent that the numbers of carbon sheet have an influence the load and displacement capacity. However, the bond length of carbon sheets for connecting beam and column has to be considered to improve the capacity of joint.

• Journal of Korean Neurosurgical Society
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• v.44 no.5
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• pp.303-307
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• 2008

Objective: The authors reviewed clinical and radiological outcomes in patients with three column injury of the cervical spine who had undergone posterior cervical fixation using Nitinol shape memory alloy loop in the anterior-posterior combined approach. Materials: Nine patients were surgically treated with anterior cervical fusion using an iliac bone graft and dynamic plate-screw system, and the posterior cervical fixation using Nitinol shape memory loop ($Davydov^{TM}$) at the same time. A retrospective review was performed. Clinical outcomes were assessed using the Frankel grading method. We reviewed the radiological parameters such as bony fusion rate, height of iliac bone graft strut, graft subsidence, cervical lordotic angle, and instrument related complication. Results: Single-level fusion was performed in five patients, and two-level fusion in four. Solid bone fusion was presented in all cases after surgery. The mean height of graft strut was significantly decreased from $20.46{\pm}9.97mm$ at immediate postoperative state to $18.87{\pm}8.60mm$ at the final follow-up period (p<0.05). The mean cervical lordotic angle decreased from $13.83{\pm}11.84^{\circ}$ to $11.37{\pm}6.03^{\circ}$ at the immediate postoperative state but then, increased to $24.39{\pm}9.83^{\circ}$ at the final follow-up period (p<0.05). There were no instrument related complications. Conclusion: We suggest that the posterior cervical fixation using Nitinol shape memory alloy loop may be a simple and useful method, and be one of treatment options in anterior-posterior combined approach for the patients with the three column injury of the cervical spine.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.30 no.1 s.244
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• pp.76-83
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• 2006

This paper addresses the method for the shape design sensitivity analysis of the buckling load in the continuous elastic body. The sensitivity formula for critical load is analytically derived and expressed in terms of shape variation, based on the continuum formulation of the stability problem. Though the buckling problem is more efficiently solved by the structural elements such as beam and shell, the elastic solids are considered in this paper because the solid elements can be used in general for any kind of structures whether they are thick or thin. The initial stress and buckling analysis is carried out by the commercial analysis code ANSYS. The sensitivity is computed by using the mathematical package MATLAB using the results of ANSYS. Several problems including straight and curved beams under compressive load, ring under pressure load, thin-walled section and bottle shaped column are chosen to illustrate the efficiency of the presented method.