• Clinical and Experimental Pediatrics
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• v.64 no.12
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• pp.608-618
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• 2021

Hypoxic-ischemic encephalopathy (HIE) is the most common cause of neonatal encephalopathy with a global incidence of approximately 1 to 8 per 1,000 live births. Neonatal encephalopathy can cause neurodevelopmental and cognitive impairments in survivors of hypoxic-ischemic insults with and without functional motor deficits. Normal neurodevelopmental outcomes in early childhood do not preclude cognitive and behavioral difficulties in late childhood and adolescence because cognitive functions are not yet fully developed at this early age. Therapeutic hypothermia has been shown to significantly reduced death and severe disabilities in term newborns with HIE. However, children treated with hypothermia therapy remain at risk for cognitive impairments and follow-up is necessary throughout late childhood and adolescence. Novel adjunctive neuroprotective therapies combined with therapeutic hypothermia may enhance the survival and neurodevelopmental outcomes of infants with HIE. The extent and severity of brain injury on magnetic resonance imaging might predict neurodevelopmental outcomes and lead to targeted interven tions in children with a history of neonatal encephalopathy. We provide a summary of the long-term cognitive outcomes in late childhood and adolescence in children with a history of HIE and the association between pattern of brain injury and neurodevelopmental outcomes.

• Dementia and Neurocognitive Disorders
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• v.22 no.1
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• pp.1-15
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• 2023

The Seoul Neuropsychological Screening Battery (SNSB) is known as a representative comprehensive neuropsychological evaluation tool in Korea since its first standardization in 2003. It was the main neuropsychological evaluation tool in the Clinical Research Center for Dementia of South Korea, a large-scale multi-center cohort study in Korea that was started in 2005. Since then, it has been widely used by dementia clinicians, and further solidified its status as a representative dementia evaluation tool in Korea. Many research results related to the SNSB have been used as a basis for the diagnosis and evaluation of patients in various clinical settings, especially, in many areas of cognitive assessment, including dementia evaluation. The SNSB version that was updated in 2012 provides psychometrically improved norms and indicators through a model-based standardization procedure based on a theoretical probability distribution in the norm's development. By providing a score for each cognitive domain, it is easier to compare cognitive abilities between domains and to identify changes in cognitive domain functions over time. Through the development of the SNSB-Core, a short form composed of core tests, which also give a composite score was provided. The SNSB is a useful test battery that provides key information on the evaluation of early cognitive decline, analysis of cognitive decline patterns, judging the severity of dementia, and differential diagnosis of dementia. This review will provide a broad understanding of the SNSB by describing the test composition, contents of individual subtests, characteristics of standardization, analysis of the changed standard score, and related studies.

• School Mathematics
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• v.19 no.2
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• pp.289-317
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• 2017

This study aims to explore how Korean middle-school mathematics textbooks on functions provide students an opportunity-to-learn [OTL]. For this purpose, we investigate 3 textbooks in terms of mathematics content and practice, the level of cognitive demands of mathematical tasks, types of student responses, types of context-based tasks, and connections among the tasks. The findings from the data analysis suggest as follows: a) an opportunity-to-learn to connect procedures to functional concepts and new ideas of functions to the existing one is very limited; b) the textbooks seem to provide students an OTL to understand functions as definitions, rules and conventions and to experience repeatedly procedural executions through worked examples and mathematics tasks; c) students may not experience to explain their own ideas/thinking by using mathematical sentence or justify their own cognitive processes; and d) students can be exposed to get a sense of mathematics as a set of fragmented and isolated facts or procedures, rather than to encourage to expand and deepen their understanding of functions.

• Korean Journal of Biological Psychiatry
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• v.9 no.2
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• pp.103-111
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• 2002

Neurocognitive research focusing on cognitive deficits in Depression has resulted in several important but yet potentially contradictory findings. Much literature documents the presence of significant neurocognitive impairments in depressive patients. Studies have shown that dysthymic disorder patients demonstrate a diffuse pattern of cognitive impairment which is frequently indistinguishable from that of focal braindamaged patients. Some reports have suggested that there is a focal pattern of deficit, such as anterior cingulate dysfunction, frontal lobe impairment, or dysfunction of the temporal-limbic cortex. The aim of this study is to evaluate the neurocognitive functions in dysthymic disorder patients, and to compare the functions with those of major depressive disorder patients. The subjects are 17 dysthymic disorder patients. And their neurocognitive functions are compared with those of 23 major depressive episode patients. Patients with a history of neurologic disease, alcohol dependence, substance abuse and mental retardation are excluded. They are assessed with a part of Vienna Test System which is computerized neurocognitive function tests and can evaluate attention, eductive ability, reproductive ability, visuoperceptual analysis, vigilance, visual immediate memory, the speed of information-processing, judgement, and fine motor coordinations. There are no other specific difference between two groups, except the result of cognitrone test. This study provides information about the neurocognitive functions and some difference between major depressive disorder patients and carefully diagnosed dysthymic disorder patients.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.32 no.3
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• pp.93-98
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• 2021

Electroencephalography (EEG) measures neural activation due to various cognitive processes. EEG and event-related potentials (ERPs) are widely used in studies investigating psychopathology and neural substrates of psychiatric diseases in children and adolescents. The present study aimed to review recent ERP studies in child and adolescent psychiatry. ERPs are non-invasive methods for studying synaptic functions in the brain. ERP might be a candidate biomarker in child-adolescent psychiatry, considering its ability to reflect cognitive and behavioral functions in humans. For the EEG study of psychiatric diseases in children and adolescents, several ERP components have been used, such as mismatch negativity, P300, error-related negativity (ERN), and reward positivity (RewP). Regarding executive functions and inhibition in patients with attention-deficit/hyperactivity disorder (ADHD), P300 latency, and ERN were significantly different in patients with ADHD compared to those in the healthy population. ERN showed meaningful changes in patients with anxiety disorders, such as generalized anxiety disorder, separation anxiety disorder, and obsessive-compulsive disorder. Patients with depression showed significantly attenuated RewP compared to the healthy population, which was related to the symptoms of anhedonia.

• Journal of Korean Academy of Medicine & Therapy Science
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• v.10 no.2
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• pp.59-71
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• 2018

Objective: The purpose of this study is to compare the effects of the CO-OP program using cognitive strategy on the satisfaction and high-level cognitive function of chronic stroke patients with cognitive impairment with the existing task-oriented approach training method. Method: The group randomly selects the experimental group and control group from 30 patients who suffer cognitive damage due to brain damage, and then randomly presents the Cognitive Orientation to daily Occupative Performance (CO-OP) Results: The results of the study showed a significant increase in patient performance and satisfaction, task performance, and high-level cognitive functions in comparison to those before training (p<).05) There was no significant difference in CNT testing in controls; Although there were no significant differences in overall CNT testing between the two groups, the COPM, AMPS tests showed a significant increase in the experimental group compared to the comparators (p <.05). Conclusion: The Cognitive Orientation to Daily Occupative Performance (CO-OP) Intervention Act, which uses meta-in strategies, was previously used. We were able to confirm that it could be a more effective intervention in task performance and high-level cognitive function than in the Meaningful Task-Specific Training Program (MTST).

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.22 no.4
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• pp.302-306
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• 2011

Objectives : To investigate the cognitive functions of pediatric cancer patients and to test the hypotheses that the impairment of processing speed and working memory are more prevalent in children with medulloblastoma (MBL) compared to children with neuroblastoma (NBL). Methods : We gave the Korean version of the Wechsler Intelligent Scale for Children-III to 21 children with MBL and 24 children with NBL during outpatient follow-up after the treatment was completed. Results : Children with MBL showed below average performance across most of the sub-tests. The full scale IQ, verbal IQ, and performance IQ of children with MBL were significantly lower than those of children with NBL. There were significant differences between two groups in coding and Digit Span subtest scores. Children with MBL performed especially poorly in the coding subtest. Conclusion : These findings support previous reports of generally low IQ and the dysfunction of processing speed and working memory among children with MBL, a kind of central nervous system tumor. Further investigation is needed to determine how the deficit of processing speed and working memory affect neurocognitive development and general intelligent functions.

• 한국노년학
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• v.31 no.4
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• pp.1103-1118
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• 2011

This study aims to examine the effects of employment on the physical health, psychological function, and life satisfaction of the elderly. Participants were 4,165 persons (men 1,739, women 2,426) aged 65 over. Physical health was composed of ADLs(Activities of daily living), pains, and disorders. Psychological function was measured by cognitive functions (subtraction, instruction execution, memory test, and item use) and emotional difficulty. Life satisfaction, work satisfaction, and work level were also measured. Major findings in this study are as follows: First, gender, marriage, and education level had significant effects on the participants' life satisfaction, but religion and financial incomes did not. Second, employment had significant effects on their physical health, psychological function, and life satisfaction. Third, pain, cognitive functions, emotional difficulty, and work satisfaction had significant effects on the life satisfaction of the working elderly. But, work level and incomes had not significant effects on the elderly's life satisfaction. In addition, an interaction between cognitive functions and emotional difficulty on life satisfaction was found.

• Korean Journal of Cognitive Science
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• v.27 no.1
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• pp.61-99
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• 2016

This research investigated that participants' response time and recognition in the decision-making situation would vary according to either rational or emotional stimuli and analyzed how brain functions are related to each type of stimuli by means of fMRI. We tried to address the difference of cognitive processing between rational stimuli and emotional stimuli in the perspective of information processing theory. In order to achieve the research purpose above, we conducted two kinds of experiment studies. In study 1, subjects conducted decision-making task which selected which kind of information type the stimuli was after stimuli - rational stimuli or emotional stimuli - was randomly seen during experiment. During this experiment, we investigated the effect of each stimuli by measuring the duration from the onset time at which stimuli was shown to the response time at which subjects conducted decision-making. Furthermore, we compared the brain functions by finding out what kinds of brain areas were activated during the decision-making task. In study 2, subjects conducted recognition task at which subjects made a decision whether the stimuli was sees in the previous experiment or not. During the second experiment, we investigated the recognition effect by measuring the memory for each stimuli type. Moreover, we compared the cognitive processes during recognition by analyzing the differences of brain area functions. The results of two experiments above were as following. Firstly, regarding the response time as the effect of stimuli, we found that the effect of emotional stimuli was higher than that of rational stimuli. And regarding the recognition as the effect of stimuli, it was found that the effect of rational stimuli was higher than that of emotional stimuli. Secondly, the explanation about the characteristics of cognitive processes with the result of behavioral response by analyzing brain functions was as following. First of all, regarding the decision-making task which conducted for analyzing the effect of response time, the relatively high activated brain areas of rational stimuli were related with the functions of movement control or working memory, and the relatively high activated brain areas of emotional stimuli were connected with the functions of lingual processing.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.7
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• pp.4656-4667
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• 2015

The purpose of this study was to investigate relations among the quality of life, health states, physical functions, cognitive functions, and social supports of the elderly at care facilities. The subjects include the elderly that were living in care facilities in some urban areas and aged 65 or older. The data of total 260 old people were used in analysis. Collected data were analyzed with descriptive statistics, t-test, ANOVA, Pearson correlation, and stepwise multiple regression. The elderly at care facilities, who were considered as physically and cognitive vulnerable, scored higher means on quality of life when they were satisfied with the length of stay and sleeping state, had higher subjective health states, had no tooth inconvenience and forgetfulness, suffered from a lower level of depression, had better cognitive functions, and received higher social supports. Quality of life had correlations with the sleeping state(r=-.20, p<.001), subjective health state(r=-.24, p<.001)s, depression(r=-.30, p<.001), and social supports(r=.30, p<.001). Social supports(${\beta}=.30$, p<.001), depression(${\beta}=-.25$, p<.001), subjective health states(${\beta}=-.22$, p<.001), length of stay(${\beta}=-.22$, p<.001), and sleeping state(${\beta}=-.12$, p=.025) turned out to predict the quality of life of the elderly at care facilities and have close relations with it. In short, the quality of life of the elderly is related to many different factors at care facilities. The findings indicate that nursing interventions and managements for quality of life require a mental and social approach or a whole person approach with a focus on the understanding of individual senior citizens rather than on physical activities and diseases.