• Journal of Pharmaceutical Investigation
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• v.39 no.4
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• pp.269-273
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• 2009

The objective of this investigation was to develop a gastro-retentive(GR) dosage form of gabapentin and was to evaluate of its dissolution characteristics. GR tablet consists of expandable core tablet matrix and semi-permeable membrane coating. Poloxamer 407 and sodium bicarbonate were used to prepare the core matrix. Polyvinly acetate dispersion (Kollicoat $SR30D^{(R)}$) and polyvinyl alcohol-polyethylene glycol copolymer ((Kollicoat $IR^{(R)}$)) were employed to form the semi-permeable membrane. The GR tablets significantly expanded up to fivefold in simulated gastrointestinal fluids with no apparent damage of the coating membrane over 12 hours. Also, the swelling rate was controllable with the amount of sodium bicarbonate. The drug release was observed to be substantially sustained based on coating level. The release rate of gabapentin from the GR tablet was gradually slowed down as the coasting amount was increased. The gabapentin GR tablet with 8% coating level showed a pseudo-zero order release kinetics over 12 hours. These results suggest that this swellable GR tablet system having semi-permeable membrane coating can be applicable for hydrophilic drug substances like gabapentin.

• Journal of the Korean Society for Railway
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• v.12 no.5
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• pp.772-777
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• 2009

The development of fuel cell hybrid power system, as a next generation power system to promote clean energy which will mitigate the continued global warming, has demonstratd a significant progress in passenger vehicle applications. Also, in case of railway vehicles in non-electrified railway lines, the adoption of fuel cell hybrid power system is being studied among well-known manufacturers. This paper introduces both the configuration and the control strategy of fuel cell hybrid power system to apply to a light electronic railway vehicle having a repeated driving pattern of acceleration, coasting and deceleration. The simulation results demonstrate the viability of the proposed power system design and its control strategy.

• Aerospace Engineering and Technology
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• v.12 no.1
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• pp.189-199
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• 2013

This paper summarizes results of second stage attitude control of KSLV-I third flight test. The results show that three axes attitude control at coasting phases of KSLV-I was successfully accomplished by the reaction control system, and pitch and yaw attitude control at thrusting phase where second stage kick motor burns was also normally accomplished by using the thrust vector control system. It is verified that the second stage controller performed successfully for all flight phases regardless of some disturbances due to mass center offset, slag effects, and residual thrust of kick motor. These results may provide an important basis in enhancing domestic technology level of attitude control of launch vehicle.

• Journal of the Korean Society of Safety
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• v.28 no.3
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• pp.23-28
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• 2013

This study focuses on finding ways to derive train's optimal ECO driving pattern, which can improve the ride quality and reduce driving energy consumption with keeping the time interval between the stations. As research method, we compared difference of currently operating train's ATO and MCS driving patterns, and concentrated upon the things need to consider in simulation in order to improve the existing pattern of ATO driving pattern's issues with securing the train operation safety. Determining driving pattern minimizing energy consumption by controlling powering within speed limit and controlling switching to coasting at appropriate point considering the track conditions for each section, and determining braking control starting time considering ride comfort and precise stopping is considered to be most important.

• Transactions of the Korean Society of Automotive Engineers
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• v.15 no.1
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• pp.38-48
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• 2007

this paper analyses how much acceleration and deceleration of urban rail vehicle should be applied and how to choose an operation mode to minimize energy consumption when train runs between stations within the fixed operation time. The decided operation pattern satisfying the minimum energy consumption becomes a target trajectory and a basis for the controller design criteria. To make this goal it grasps the characteristics of urban rail vehicle, realize operation energy model of urban rail vehicle and verity the accuracy of embodied model the Matlab simulation with the same operation result of real route. It searches for operation pattern to minimize operation energy by changing the acceleration and deceleration on the imaginative route and proposes operation pattern minimizing energy consumption by applying real operation data between stations of Seoul Metropolitan Subway Line 6.

• Journal of Astronomy and Space Sciences
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• v.38 no.2
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• pp.145-155
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• 2021

In this work, preliminary launch opportunities from NARO Space Center to the Sun-Earth Lagrange point are analyzed. Among five different Sun-Earth Lagrange points, L1 and L2 points are selected as suitable candidates for, respectively, solar and astrophysics missions. With high fidelity dynamics models, the L1 and L2 point targeting problem is formulated regarding the location of NARO Space Center and relevant Target Interface Point (TIP) for each different launch date is derived including launch injection energy per unit mass (C3), Right ascension of the injection orbit Apoapsis Vector (RAV) and Declination of the injection orbit Apoapsis Vector (DAV). Potential launch periods to achieve L1 and L2 transfer trajectory are also investigated regarding coasting characteristics from NARO Space Center. The magnitude of the Lagrange Orbit Insertion (LOI) burn, as well as the Orbit Maintenance (OM) maneuver to maintain more than one year of mission orbit around the Lagrange points, is also derived as an example. Even the current work has been made under many assumptions as there are no specific mission goals currently defined yet, so results from the current work could be a good starting point to extend diversities of future Korean deep-space missions.

• KSBB Journal
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• v.14 no.3
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• pp.297-302
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• 1999

The polymeric matrices coated with poly(DL-lactide) were prepared using chitosan derivatives such as chitosan, chitosan hydrochloride, and sulfonated chitosan for application of drug delivery systems. The drug release study using prednisolone as a model drug was performed in the hydrochloride solution at pH 1.2. The release rate of drug was decreased according to the increased content of matrices. The release rate of prednisolone according to the kinds of polymeric matrices coated were decreased in the order to chitosan, sulfonated chitosan, and chitosan hydrochloride. Drug release rate of polymeric matrices coated with poly(DL-lactide) was not only two times slower than noncoated one, but also the burst effect of initial period of drug release was decreased in comparison with noncoated one. From these results, it was expected that these formulations based on the chitosan derivative matrices coasted with poly(DL-lactide) were acceptable drug delivery devices for a sustained-release dosage form of drug.

• Transactions of the Korean Society of Automotive Engineers
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• v.24 no.6
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• pp.635-641
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• 2016

Regenerative braking performance of an electrically powered vehicle is closely related to driving distance per battery charge. An electric vehicle uses appropriate amounts of mechanical braking force and electromagnetic regenerative braking force to recover energy and increase driving efficiency. In particular, when it drives on a downhill road, energy recovery rate is maximized through regenerative braking during coasting based on the mass inertia of the vehicle. Since an electric two-wheeled vehicle covered in this paper is lighter than an electric four-wheeled vehicle, the improvement of its driving distance per battery charge through regenerative braking is different from an electric four-wheeled vehicle. This study compared the driving characteristics of an electric two-wheeled vehicle based on regenerative braking. Two driving test modes were simulated with a chassis dynamometer system. By analyzing the measurement of a chassis dynamometer, the driving characteristics of a two-wheel electric vehicle, such as driving efficiency, were analyzed. In addition, test results were reviewed to draw the limitations of conventional test methods for regenerative braking performance of an electric two-wheel vehicle.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.64 no.10
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• pp.1523-1527
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• 2015

Traction power is supplied by three-phase alternating current of 154 kV power grid and electric trains are operated on single phase feeding system. It becomes important to use all the three phases equally and convert them into two-phase electric power (90 degree phase rotation) for traction supply. This is achieved by special transformer from the adjacent traction substation which is separated by a neutral section. Neutral section locations are in front of the substation and between the two substations. The first stage of the Seoul-Busan high-speed railway, design curve radius is larger than 7,000 m and the greatest slope is 25‰. The railway track conditions are evaluated as good enough to install a neutral section at the first stage, but a few factors of coasting operation of the train should be considered at the second stage of Seoul-Busan high-speed railway. The neutral section was located at Kim-cheon substation, which made some neutral section problems produced by the operating train, and the neutral section was moved about 1.5 km to the south toward Dong Dae-gu station due to the track operation condition. Some of the trains which stopped at the existing Kim-cheon Gu-mi station produced another motor block failure after moving the neutral section. In this paper, power quality, system performance and track condition, etc. are suggested to solve the problems.

• Journal of the Korean Society of Propulsion Engineers
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• v.23 no.3
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• pp.119-126
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• 2019

For rockets using cryogenic liquid hydrogen or liquid oxygen, chilling is required to avoid cavitation and surge problems. Chilling is categorized by the initial chilling/filling stage and the low-temperature maintenance stage. In addition, to improve satellite insertion capability, a multi-ignition capability is required and accordingly chilling to prepare for the next ignition during low-gravity coasting is also required. This paper describes the overall aspects of filling and low temperature maintain marinating for the booster and the upper stage engine including chilling for multi-ignition.