• 제목/요약/키워드: clinical significance

검색결과 2,175건 처리시간 0.035초

Adiponectin Reference Range설정과 임상적 의의 고찰 (Setting of Adiponectin Reference Range and Clinical Significance of investigation)

  • 김용하;오춘순;이안나
    • 핵의학기술
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    • 제12권1호
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    • pp.82-87
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    • 2008
  • Purpose: The Bio-energy metabolism control hormone by Adipocytokine is composed with Leptin, Adiponectin, resistin, TNF-a, IL-6. Adiponectin become known to participating in Insulin sensitivity exasperation, Fat metabolism accomodation and inducing metabolic disease such as diabetes mellitus, arteriosclerosis, hyperlipemia. When we accomplished the test with purpose of Research, we observed significance with a result of test related to diabetes mellitus with reference setting by way of suggestion. Methods: Result of normal group (n=100) which is committed in the SCL from September 2006 to December 2006 and result of control group (n=50) relationship examination item that is decided diabetes measures themselves against each other. Also, we measured the normal group against the control group for the reference range of adiponectin. Results: Result in normal group (n=100) appeared by Glucose (reference 70~120 mg/dl) Mean and the SD 96.99 (${\pm}24.35$), HbA1c (reference 4.0~6.0%) Mean and the SD 5.64 (${\pm}0.90$), Insulin (reference 2.0~25.0 uIU/ml) Mean and the SD 7.80 (${\pm}4.42$), the Adiponectin the Mean and the SD 9,861.23 (${\pm}4,977.0$). Result in control group(n=50) appeared by Glucose (reference 70-120 mg/dl) Mean and the SD 224.95 (5.30), the HbA1c (reference 4.0~6.0%) Mean and the SD 8.22 (1.63), Insulin (reference 2.0~25.0 uIU/ml) Mean and the SD 17.02 (3.01), C-peptide (reference 0.48~3.30 ng/ml) Mean and the SD 7.92 (${\pm}7.40$), the Adiponectin Mean and the SD 18,110.03 (${\pm}12,843.29$). Conclusions: Therefore, it seems that test results are significant and we consider that it can be apply to useful diagnosis of diabetes mellitus, arteriosclerosis, hyperlipemia patients throughout the reference range setting of Adiponectin, Leptin is one of the Bio-energy metabolism control hormone.

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대사성 뇌병증에서 삼상파의 중요성 (Significance of Triphasic Waves in Metabolic Encephalopathy)

  • 박강민;신경진;하삼열;박진세;김시은;김형찬;김성은
    • Annals of Clinical Neurophysiology
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    • 제16권1호
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    • pp.15-20
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    • 2014
  • Background: Triphasic waves are one of the electroencephalographic patterns that can be usually seen in metabolic encephalopathy. The aim of this study is to compare the clinical and electrophysiologic profiles between patients with and without triphasic waves in metabolic encephalopathy, and reassess the significance of triphasic waves in metabolic encephalopathy. Methods: We recruited 127 patients with metabolic encephalopathy, who were admitted to our hospital. We divided these admitted patients into two groups; those with and without triphasic waves. We analyzed the difference of duration of hospitalization, mortality rate during admission, Glasgow Coma Scale, severity of electroencephalographic alteration, and presence of acute symptomatic seizures between these two groups. Results: Of the 127 patients with metabolic encephalopathy, we excluded 67 patients who did not have EEG, and 60 patients finally met the inclusion criteria for this study. Patients with triphasic waves had more severe electroencephalographic alterations, lower Glasgow Coma Scale, and more acute symptomatic seizures than those without triphasic waves. After adjusting the clinical variables, Glasgow Coma Scale and acute symptomatic seizures were only significantly different between patients with and without triphasic waves. Conclusions: We demonstrated that patients with triphasic waves in metabolic encephalopathy had more significant impairment of the brain function.

Bowel Wall Thickening on Computed Tomography in Children: A Novel Method of Measurement and Its Clinical Significance

  • Lee, Do Kyung;Cho, Ky Young;Cho, Hyun-hae;Seo, Jeong Wan
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제24권3호
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    • pp.279-287
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    • 2021
  • Purpose: The clinical implications of bowel wall thickening (BWT) on abdominal computed tomography (CT) among children are unknown. We aimed to suggest a new method for measuring BWT and determining its clinical significance in children. Methods: We retrospectively analyzed 423 patients with acute abdomen who underwent abdominal CT; 262 were classified into the BWT group. For this group, the pediatric radiologist described the maximal bowel wall thickness (MT), normal bowel wall thickness (mm) (NT), and their ratios for each segment of the bowel wall. Results: In the thickened bowel walls, the thickness differed significantly between the small bowel (6.83±2.14 mm; mean±standard deviation) and the colon (8.56±3.46 mm; p<0.001). The ratios of MT to NT in the small bowel (6.09±3.17) and the colon (7.58±3.70) were also significantly different (p<0.001). In the BWT group, 35 of 53 patients had positive fecal polymerase chain reaction results; 6 patients infected with viruses predominantly had BWT in the small intestine, while the terminal ileum and the colon were predominantly affected in 29 patients with bacterial infections. In the initially undiagnosed 158 patients with BWT, the symptoms improved spontaneously without progression to chronic gastrointestinal disease. Conclusion: This study provides a clinical reference value for BWT in the small intestine and colon using a new method in children. The BWT on abdominal CT in children might indicate nonspecific findings that can be observed and followed up without additional evaluation, unlike in adults.

치기공과 학생의 임상실습 환경과 안전에 관한 연구 (A Study about Clinical Training Environment and Safety of Dental Technology Students)

  • 정효경
    • 대한치과기공학회지
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    • 제38권4호
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    • pp.343-352
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    • 2016
  • Purpose: The intention of the study is to reveal the factors that influence the safety-behavior and safety-accident of the students of dental laboratory science. We intend to use the study as a basic data of searching effective ways to heighten the safety-behavior of clinical training and to prevent safety-accident. Methods: The survey was conducted on dental technology students. The collected data was analyzed by the statistical program SPSS 21.0. The results were analyzed by reliability, frequency, t-test, correlation, multiple regression. To test for significance on each item, p<0.05 has been decided as a standard. Results: The results of the study showed that the safety of the students was influenced by the school year, the leader of clinical training, clinical training environment and the experience of safety education. The safety-accident turned out to be influenced by the school year of the student and the safety behavior. Conclusion: Active leader of clinical training, clinical training environment that enables the safety-behavior, and the offering of the systematic safety education were the most important factors to heighten the safety behavior of the students and prevent the safety-accident. These factors were expected to not only induce the safety-behavior but also prevent the safety-accident as well.

주의력결핍과잉활동 장애의 평가 (ASSESSMENT OF CHILDREN WITH ATTENTION DEFICIT HYPERACTIVITY DISORDER)

  • 오경자
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제1권1호
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    • pp.65-76
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    • 1990
  • 주의력결핍-과잉활동장애(ADHH)는 그 행동적 특징이 정상아동들간에도 흔히 나타날 수 있는 것으로 정상적 발달과정에서 나타나는 현상과의 구별이 어려운 경우가 있어 증상의 심각도를 양적수치로 평가하는것과 아울러 함께 각 연령별 규준에 비추어 판단하는 객관적 평가방법이 필요하다. 또한 ADHD의 증상은 상황에 따라, 그리고 사회적 맥락에 따라 나타나는 양상이 크게 다를수도 있어 가능한한 다양한 상황에서의 행동을 여러 평가자로부터 평가받아 이를 통합하는 과정이 필요하다. 구체적으로 부모 및 환아와의 면담, 각종 행동평가 척도, 행동의 관찰, 그리고 심리검사등 ADHD를 평가할 때 사용할 수 있는 방법 및 척도들이 논의되었으며, 평가의 목적에 따라 적절한 도구를 선택하여 활용하는 체계적이고 종합적인 평가의 중요함이 강조되었다.

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방사면역측정법(放射免疫測定法)에 의한 혈중(血中) 유리(遊離) Thyroxine 농도측정(濃度測定)의 임상적(臨床的) 의의(意義)에 대(對)한 검토(檢討) (Studies on the Clinical Significance of Free Thyroxine Concentration in Serum by Radioimmunoassay)

  • 이준일
    • 대한방사선기술학회지:방사선기술과학
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    • 제11권1호
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    • pp.25-31
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    • 1988
  • Studies on the clinical significance with Amerlex $FT_{4}$ RIA kit observing the determination of $FT_{4}$ were investigated using a tracer as $^{125}I-T_{4}$ derivative which is not almostly bound to thyroxine binding globulin, etc. The results are followed; 1. $FT_{4}$ value($1,55{\pm}0.38ng/100ml$) of normal group was not accorded that of hyperthyroidism with Amerlex $FT_{4}$ RIA kit, and was higher than that of hypothyroidism. 2. $FT_{4}$ value was lower level in chronic-kidney disfunction syndrome whereas, it was normal in a cancer patient, a woman in pregnancy and a patient in TBG disfunction. 3. The value of this method is a good corelationship at that of equilibrium dialysis method. (r=0.931) 4. $FT_{4}$ value by this kit was linear relationship to those of the other kit (Gamma Coat and Liquisol), and the normal value of each methods was also similar. As mentioned above, this method is more simple and rapid, compared to the other method. Therefore, it was thought that this method is a very useful clinically.

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