• Korean Journal of Clinical Laboratory Science
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• v.40 no.2
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• pp.129-134
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• 2008

Obstructive sleep apnea syndrome (OSAS) is occurred by apnea by the obstruction of upper trachea while sleeping, followed by repetitive drop on arterial oxygen saturation ($SpO_2$). Therefore, the present study was focused on relation between $SpO_2$ of while having difficulty in breathing and clinical characteristics of OSAS while sleeping. The study took place at Ewha women university Mokdong hospital with 149 subjects (male 121, female 28) who were examined for polysomnography (PSG) from May 2007 to February 2008. All subjects were adhered to electrodes and sensors to measure electroencephalogram (EEG), electrooculogram (EOG), chin & leg electromyogram (EMG), airflow at nasal and oral cavities, breathing movement of chest and abdominal snoring sound and $SpO_2$. Lowest $SpO_2$ in male was meaningfully low with higher body mass index (BMI), louder snoring sound and thick neck circumference (p<0.01). While mean $SpO_2$ based on the degree of AHI did not show significant difference, lowest $SpO_2$ was significantly low with high AHI (p<0.001). Also, lowest $SpO_2$ was closely correlated with BMI (r=-00.343, p<0.001), snoring sound (r=0.177, p<0.05), apnea index (r=-0.589, p<0.001), hypopnea index (r=-0.336, p<0.001) and apnea-hypopnea index (r=-0.664, p<0.001). $SpO_2$ was closely related to clinical characteristics of OSAS, like male, BMI, snoring sound and neck circumference. Also, polysomnography accompanied by recent development of sleep study is considered as critical test to diagnose OSAS, decide the severity of illness, and evaluate the treatment plan.

• The Journal of Korean Physical Therapy
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• v.21 no.4
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• pp.111-115
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• 2009

Purpose: The aim of this study was to present fundamental information regarding clinical prognosis and clinical criteria for therapeutic intervention in stroke patients with focal pons infarction. Methods: Four stroke patients (male: 2, female: 2) who were diagnosed with pons infarction were recruited. All subjects had motor functions evaluated using methods such as the Motricity Index (MI), the Modified Brunnstrom Classification (MBC), Functional Ambulatory Category (FAC), and the Bathel Index (BI). Evaluations were done at least 4 times over a period that was approximately 8~11 months from stroke onset. We compared the final evaluation with the first evaluation. Results: All patients with focal pons infarction showed improvement with time in motor function. The physical strength of all patients was improved to normal or good grades from zero or trace grades in the Motricity Index test. Also, other motor functions such as ambulatory capacity and activities of daily living (ADL) improved with time. Conclusion: Aspects of functional recovery and clinical prognosis are clearly predictable for specific patients with focal pons infarction. In addition, adequate therapeutic interventions can be provided clinical criterion to patients, according to aspect of functional recovery. Accordingly, patients with pons infarction change for the better over time.

• Journal of the Korean Applied Science and Technology
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• v.36 no.1
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• pp.113-124
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• 2019

The purpose of the study was to investigate the effects of sea cucumber extract on skin as a natural cosmetics functional material. Subjective evaluation of cosmetics before and after were conducted with questionnaires regarding moisture content, sebum content, melanin index, and erythema index. Experiments were conducted on improvement efficacy using skin clinical trials and questionnaires to evaluate changes in perception of skin condition and efficiency of products. With the aim of minimizing skin irritation, the efficiency of the solvent used for extraction was an important factor, and the sea cucumber extract was harvested with efficient extraction conditions at a ratio of 1:10 of 50% ethanol. The study aimed to identify the suitability of sea cucumber extract as a functional cosmetics material to improve the moisturizing ability of skin and its effect on the skin by adding marine natural animal sea cucumber extract. Clinical studies on cosmetics skin containing sea cucumber extract, excellent skin improvement effect from all items of clinical experiment in experimental and control groups. Sea cucumber extract was proved to be a stable, non-adverse physiologically active substance against abnormal symptoms or side effects of skin reactions and skin problems. In addition, the study found excellent results that can lead to its use as a cosmetics material. This is expected to contribute to the development of various cosmetics industries.

• Journal of Digital Convergence
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• v.17 no.8
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• pp.357-365
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• 2019

This study was conducted to identify correlations in clinical nurses' personality, resilience and happiness index to provide basic resources for nurses' happiness at work. Methods: From May 1 to 15, 2019, self-report questionnaires were distributed and collected from 307 of clinical nurses in 10 hospitals located in P-metropolitan city and K-province. Analyses included descriptive statistics, t-test, Analysis of Variance, Pearson's correlation coefficient, and multiple regression, conducted using IBM SPSS/WIN 24.0. Mean scores were nurses' personality 3.67, resilience 3.28, and happiness index 3.28. There were significant differences on the happiness index for: clinical experience, type of work, and leisure activities and a positive correlation between personality and resilience, between personality and happiness index and between happiness index and resilience. Happiness index was influenced by clinical experience 'Less than 1-5' (${\beta}=-.41$), '${\geq}10$' ${\beta}=-.39$), 'Less than 5-10' (${\beta}=-.34$), resilience (${\beta}=.35$), personality (${\beta}=.29$), type of work '3 shifts' (${\beta}=.12$), leisure activities (${\beta}=.10$). Explanatory power of these variables was 41%. Conclusion: Based on the findings of this study, so it is necessary to operated the career management, work management, personality training, support for resilience promotion program and leisure activities in order to increase the happiness index of hospital nurses.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.939-944
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• 2016

Background: Cell-free DNA circulating in blood is a candidate biomarker for malignant tumors. Unlike uniformly truncated DNA released from apoptotic non diseased cells, DNA released from necrotic cancer cells varies in size. Objectives: To measure the DNA integrity index in serum and the absolute DNA concentration to assess their clinical utility as potential serum biomarkers for colorectal carcinoma (CRC) compared to CEA and CA19-9. Materials and Methods: Fifty patients with CRC, 10 with benign colonic polyps and 20 healthy sex and age matched volunteers, were investigated by real time PCR of ALU repeats (ALU q-PCR) using two sets of primers (115 and 247 bp) amplifying different lengths of DNA fragments. The DNA integrity index was calculated as the ratio of q-PCR results of ALU 247/ALU 115bp. Results: Serum DNA integrity was statistically significantly higher in CRC patients compared to the benign and control groups (p<0.001). ROC curves for differentiating CRC patients from normal controls and benign groups had areas under curves of 0.90 and 0.85 respectively. Conclusions: The DNA integrity index is superior to the absolute DNA concentration as a potential serum biomarker for screening and diagnosis of CRC. It may also serve as an indicator for monitoring the progression of CRC patients. Combining CEA and CA19-9 with either of the genetic markers studied is better than either of them alone.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.17 no.2
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• pp.274-281
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• 2010

Purpose: The purpose of this study was to identify the correlation between level of professional autonomy and clinical decision making abilities in clinical nurses, and to provide basic information for promoting competency nurses in making independent decisions. Method: Data were collected from July 1 to July 18, 2008, and participants were 202 clinical nurses in general hospitals. Collected data were analyzed using descriptive statistics: frequency and percentage and Pearson correlation coefficients with the SPSS WIN 14.0 program. Results: The professional autonomy index for the nurses was 159.63 points. The clinical decision making ability index was 119.79 points. The most highly ranked factor in clinical decision making was search for information and unbiased assimilation of new information. There was a statistically significant difference in professional autonomy according to age, clinical experience, and type of duty. Relation between level of professional autonomy and clinical decision making showed a positive correlation. Conclusion: As a results show a significant correlation between professional autonomy and clinical decision making in clinical nurses, improvement in professional autonomy of clinical nurses, would be promoted through continuous support and training.

• Journal of Sasang Constitutional Medicine
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• v.16 no.3
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• pp.25-33
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• 2004

1. Objectives Theoretically Healthy Condition of four constitution is based on intact state of four fundamental factors - digestion, urination, perspiration, defecation. Each one of these four factors is specifically related to its respective constitution. We made SHI(Sasangin Health Index) 10 items from four factors, and examined clinical efficacy of the four factors as index of health status in four constitution. 2. Methods and Procedures We offered QSCCII, SHI and SF-36 questionnaires to adults who had a periodic medical examination. 233 adults were classified to one of four constitution. We compared means of 8 scale scores of SF-36, and computed the correlation coefficient between 8 scale scores of SF-36 and 10 item scores of SHI in four constitution. 3. Results In Soyangin, stool volume and frequency are weakly correlated with health status(P<0.05). In Soeumin, appetite is weakly correlated with health status(P<0.05). In Taeumin, there is no correlation between perspiration and health status. 4. Conclusions 2 factors - digestion, defecation - had clinical efficacy as index of health status.

• Journal of Korean Clinical Health Science
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• v.5 no.3
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• pp.880-887
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• 2017

Purpose. This study was conducted from the period of April 12th, 2017 to April 26th, 2017. The questionnaires were distributed among a group of 76 adults aged 20 years or older, who participated in the prevention program of the department of dental hygiene at Busan Metropolitan City. The negative questionnaire was finally analyzed. Methods. The SPSS program was used for analysis of this study. The general characteristics of the subjects were t-test and one-way, ANOVA(by Scheffe post-test) for a PHP index (Patient Hygiene Performance index) according to frequency analysis, general characteristics, smoking and drinking behavior, and dietary behavior. Results. As a result of an examination of the PHP index(Patient Hygiene Performance index) ac- cording to smoking and drinking behavior, the amount of alcohol drunk was statistically higher than that of 'soju that was not drunk'(P<0.05). As a result of the PHP index (Patient Hygiene Performance index) according to dietary behavior, 'vegetarians' were statistically higher than 'Carnivorous oriented' individuals (P<0.05). Moreover, individuals who regularly 'drank almost no water' were statistically significantly higher than those who 'drank water steadily'.(P<0.05). Conclusion. As a result, appropriate management is required for oral health of the patient, Oral health education is needed to systematically consider smoking, drinking, and eating habits when taking into consideration the individual oral environment.

• Biomedical Science Letters
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• v.23 no.4
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• pp.348-354
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• 2017

TyG (triglyceride and glucose) index using triglyceride and fasting blood glucose is recommended as a useful marker for insulin resistance. The present study evaluated the usefulness of TyG index in diagnosing metabolic syndrome and suggested an optimal cut-off value. The subjects of this study were adult 4,415 adults aged 20 to 80 years who underwent health screening at J General Hospital from January 2016 to January 2017. Metabolic syndrome was based on AHA/NHLBI (American Heart Association/National Heart, Lung, and Blood Institute) criteria. TyG index correlated with metabolic syndrome risk factors including HOMA-IR. Compared with the participants in the lowest quartile of TyG index, odds ratios and 95% confidence intervals for metabolic syndrome were 8.5 (3.005~23.903), 20.0 (17.190~23.407) for those in the third, and the fourth quartile of TyG index. The optimal cut-off value of the metabolic syndrome was 8.81 for TyG index (sensitivity 86.7%, specificity 80.1%) and area under the ROC curve (AUC) was 0.894. In conclusion, TyG index is effective to identify individuals at risk for metabolic syndrome.

• Journal of Periodontal and Implant Science
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• v.24 no.3
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• pp.503-512
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• 1994

The purpose of this study was to assess the clinical and microbiological effect of chlorhexidine rinse following scaling and root planing on periodontits. 10 patients with periodontal disease were selected for the study. They had not taken antibiotics for months and no history of dental treatment for 6 months before the study. They were good in general health. Patients received a scaling and root planing under local infiltration anesthesia, chlorhexidine rise group were subjected to twice a day 0.1% chlorhexidine rinse for a period 2 week. After initial clinical(plaque index, gingival index, probing pocket depth), microbiological and BANA tests were determined, each subject received a single session of scaling and root planing but no oral hygiene instructions. Clinical indices were measured, microbial parameters and BANA test were reassessed 1, 2 and 4 weeks after treatment. The results were as follows : 1. Plaque index, gingival index and pocket depth in chlorhexidine rinse group and control group were not significantly reduce during all weeks when compared chlorhexidine rinse group with control groups. Plaque index in chlorhexidine rinse group and control group were siginificantly reduced at 1, 2, 4weeks(P<0.05), gingival index and pocket depth wee ignificantly reduced at 2, 4weeks in both groups(P<0.05). 2. Perecntage of cocci and motile rods was significantly changed at 1, 2, 4weeks in chlorhexidine rinse group(P<0.05), control group was significantly changed at 4weeks in control group(P<0.05), intergroup difference was significantly at 2weeks in cocci and 4weeks in motile rods(P<0.05). 3. Percentage of non-motile rods in all group were not significantly changed when compared with those of baseline. 4. Percentage of spirochetes was significantly reduced at 4 week(P<0.05), control group was not significantly reduced during all weeks. 5. BANA test scores was significantly reduced during all weeks in chlorhexidine rinse group(P<0.05), control group was not significantly reduced during all weeks. The result showed that clinical and microbiological effect following scaling, root palning and chlorhexidine on periodontal disease.