• Title/Summary/Keyword: clinical character

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Character of Listeria spp. isolated from livestock products and their related environmental areas

  • Hur, Jin;Kim, Jun-Man;Park, Young-Ho
    • Korean Journal of Veterinary Service
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    • v.33 no.1
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    • pp.59-66
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    • 2010
  • This study was carried out to investigate the characters of Listeria monocytogenes isolated from food, animal feces, dry cattle food, and the environment in Seoul and Kyonggi province during the period from 1998 to 2003. Serotyping of 70 L. monocytogenes isolates was performed according to the manufacturer's instruction. Minimum inhibitory concentrations (MICs) were determined by the microdilution method according to the guidelines of the Clinical and Laboratory Standards Institute. All the isolates were tested against 20 antimicrobial agents. The serotypes of the 70 L. monocytogenes isolates were 1/2c (62.8%), 1/2a (20%) and 1/2b (17.2%). Of the 70 L. monocytogenes isolates, 67.1%, 57.1%, 11.4%, 5.7%, 2.8%, 1.4% and 1.4% were resistant to tetracycline (Te), minocycline (Mi), norfloxacin (Nor), ciprofloxacin (Cip), neomycin (N), chloramphenicol (C) and cephalothin (Cf), respectively. However, all isolates were 100% sensitive to antibiotics such as amikacin, ampicillin, erythromycin, gentamycin, imipenem, kanamycin, ofloxcin, streptomycin, penicillin, trimethoprim, trimethoprim/sulfamethoxazole, tobramycin, and vancomycin. Multiple resistance patterns of the isolates were observed in TeMiNor Cip (1.4%), TeMiNor (7.1%), TeMiCip (2.9%), TeMiN (1.4%) and TeMi (44.3%). The results of this study indicate that many L. monocytogenes isolates are resistant to antimicrobial agents including Te and Mi. The possibility that the isolates could increasingly acquire multiple antimicrobial resistant properties cannot be precluded.

Comparisons of Physical Activity and Sedentary Life according to Health and Obesity Level (대사적 건강 및 비만상태에 따른 신체활동과 좌식생활의 차이 비교)

  • Sa, Seok-Eun;Kim, Won-Hyun;Jo, Kyu-Kwon;Lee, Ji-Young
    • Journal of Digital Convergence
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    • v.15 no.4
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    • pp.477-488
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    • 2017
  • The purpose of this study was to investigate difference of Physical Activity and Sedentary Life according to Health and Obesity status. A total of 4,783 adults participated in this study. The subjects were divided to four group(metabolically healthy normal weight; MHNW, metabolically unhealthy normal weight; MUNW, metabolically healthy obesity; MHO, metabolically unhealthy obesity; MUO) and analyzed clinical character, physical activity, and sedentary life time. As results, Compared with MHNW, MHO was higher physical activity and sedentary time but there was no notable differences. Compared with MHNW, MUNW was higher physical activity and lower sedentary time but there was no notable differences. Compared with MUNW, MHO was lower physical activity and sedentary time but there was no notable differences. In conclusion, we suggest that MHO has high physical activity comparing nomal weight group relatively.

The Educational Needs of Mothers of Nephrotic Syndrome Patients and the Degree of the Importance of Educational Activity Perceived by Nurses (신증후군 환아 어머니의 교육요구와 간호사가 인지한 교육활동의 중요도에 관한 탐색적 연구)

  • Sung Mi Hae;Jung Yun
    • Child Health Nursing Research
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    • v.3 no.2
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    • pp.169-177
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    • 1997
  • This is descripitive study conducted to identify educational needs of mothers of nephrotic syndrome patients and the degree of the importance of educational activity perceived by nurses who look after nephrotic syndrome patients. The study subjects were composed of 60 mothers & 63 nurses of nephrotic syndrome patients whose children were hospitalized in 2 Pediatric wards of University Hospital in Seoul and 1 in Pusan from Mar. in 1997 to July 1997. A questionaire for this study was item Kikert type 5 point scale, developed on the basis of previous literature and researcher's clinical experience and the reliability of the used instruments was α=.97. The data analysis was done by SAS. t-test, and ANOVA were done to determine the effect of general characteristics of subjects on their educational needs. T-test was done to measure relations between the degree of educational needs and importance of educational activity. The results were as follows. 1. The Educational needs of mothers ranked as the highest in home care. 2. In character of mothers, the degree of education, economic state, the number of child and occupation was significant in statistically. 3. The importance of educational activity of nurses ranked the highest in diagnosis and treatment of the disease. 4. The educational needs of nephrotic syn. children' mother and importance of nurses were different in diagnosis and treatment of the disease and home care. On the basis of these results, we suggest as follows. 1. It is proposed that nurses use these results of the study actively for the educational program for Nephrotic Syndrome patients and their mothers. 2. It is suggested to make a comparative study of the degree of nurses' understanding of the importance on educational items with the instruments of this study.

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Fabrication and Medical Applications of Lotus-leaf-like Structured Superhydrophobic Surfaces (연잎 모사 구조로의 초소수성 표면 처리와 의료분야의 적용에 관한 연구)

  • Lim, Jin Ik;Kim, Seung Il;Jung, Youngmee;Kim, Soo Hyun
    • Polymer(Korea)
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    • v.37 no.4
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    • pp.411-419
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    • 2013
  • Various biomaterials have been widely used for biomedical applications, including bio-organs, medical devices, and clinical devices like vessel, blood pumps, artificial kidneys and hearts, even in contact with blood. The issue of blood compatibility has been studied intensively to prevent negative effects such as thrombosis due to the implanted devices. The use of lotus-leaf-like structured surfaces has been extended to an increasing number of applications such as contamination prevention and anticorrosion applications. Various methods such as template, sol-gel transition, layer-by-layer, and other methods, developed for the fabrication of lotus-leaf-like surfaces have been reported for major industrial applications. Recently, the non-wettable character of these surfaces has been shown to be useful for biomedical applications ranging from blood-vessel replacement to antibacterial surface treatment. In this review, we provide a summary of current and future research efforts and opportunities in the development and medical applications of lotus-leaf-like structure surfaces.

Personalities and interpersonal relationships of dental hygiene students (치위생과 학생의 인성과 대인관계)

  • Shin, Myong Suk;Hwang, Ji Min
    • The Journal of the Convergence on Culture Technology
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    • v.8 no.2
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    • pp.91-97
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    • 2022
  • This study was conducted to understand the degree of personality and interpersonal relationships among dental hygiene students. The survey was conducted from April 1, 2021 to June 30, 2021. As a result of the study, personality was 3.42 points and interpersonal relationships were 3.46 points. In general, there was a statistically significant difference in both personality and interpersonal subdomains in interpersonal satisfaction and college life satisfaction (p<.05, p<.001). The more experience they had in clinical practice, the lower their scores for friendship and professorship among interpersonal relationships. Among the sub-domains of personality, morality and sociality were analyzed as having the highest positive correlation (r=.674), and in interpersonal relationships, the relationship between friends and professors was analyzed as high (r=.606). Therefore, for the holistic growth of dental hygiene students as preliminary dental hygienists and their adaptation to the dental care field, a long-term strategy and continuous educational approach are needed at the university for cultivating character and interpersonal relationships, which are the basics. In addition, various programs related to the duties of dental hygienists should be developed and methods to be applied should be sought.

Money as a Polycontextual Value and Means of Self-Identification of a Modern Person: Traditional vs Virtual

  • S. Khrypko;Qi Yang;M. Kozlovets;I. Chornomordenko;M. Kolinko ;V. Havronenko;O. Lobanchuk;Н. Salo
    • International Journal of Computer Science & Network Security
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    • v.23 no.2
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    • pp.1-12
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    • 2023
  • The article examines the axiological psycho-philosophical understanding of the phenomenon of money and its value role in modern society. The traditional and virtual context of the representation of the money phenomenon is considered.Following the ideas of G. Simmel, the authors consider money not only as a purely economic, but also a psycho-philosophical, cultural and social phenomenon. Money appears as a result of cultural development of the world and gradually forms a monetary culture as a space of economic and social interaction of people. Under the influence of the monetary culture of one or another historical period, the character of a person's economic activity, values and life orientations are formed. Modern money culture is often called financial civilization. Peculiarities of modern monetary culture are studied, its main features and problems are determined in the article. The problem of the peculiarities of the constructive and destructive attitude of the individual towards money is identified; a psycho-philosophical and cultural-identification typology of people is described, which is based on clinical observations and interpreted through the prism of psychoanalytic theory. The concept of money is highlighted from the standpoint of a social-psychological approach. The theoretical foundations of money's influence on the decision-making process and human behavior are also revealed.

The Problem of Individuality and Intrinsic Norms in Canguilhem's Philosophy of Life (캉길렘의 생명철학에서 개체성과 내재적 규범의 문제)

  • Hwang, Su-young
    • Philosophy of Medicine
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    • v.15
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    • pp.3-37
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    • 2013
  • George Canguilhem(1904-1995) is one of the rare French philosophers of the 20th century to develop an approach that was shaped by a medical education. For him, medicine is considered as "a technique or an art at the junction of many different sciences, rather than a proper science." The thesis that medicine is a technique is presented not at a practical level, but on an axiological horizon which reflects the totality of humanity. This character of medicine became a motive that concretized Canguilhem's philosophical thinking. Medical knowledge is not an application of physiology, but is derived from clinical observations which are based on the personal experiences of each patient. If medicine were based on scientific knowledge and its practice the very application of this pure knowledge, the patient might be a passive object. However, the patient doesn't remain passive, but reacts to the menace of disease according to attitude that the patient developed over the course of his or her life. Canguilhem characterizes this point as 'normativity', the core of individual life, which eludes positivist medicine. Here appear the essential contents of his vitalism. Although they emphasized the activity of individual living being, other modern French vitalists didn't consider this dimension of norms. Since the normativity in Canguilhem concerns the subjectivity of the first person, it avoids a mechanical form of explanation. Thus Canguilhem's originality is found in his derivation of the essence of medicine from individuality, values and norms.

The current status and future tasks of the prosthodontics curriculum in Korean dental schools and graduate dental schools (치과대학 및 치과전문 대학원의 보철학 교과과정 실태 조사 및 개선 방향에 대한 고찰)

  • Kim, Jee-Hwan;Lee, Sojin;Park, Young-Bum;Chung, Moon-Kyu
    • The Journal of Korean Academy of Prosthodontics
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    • v.51 no.2
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    • pp.90-98
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    • 2013
  • Purpose: Prosthodontics education of Korean dental schools is developing under liberal regulation according to the character of each school. Diversity in the current environment and condition for each school make it impossible to apply the same and uniform education curriculum. Therefore the purpose of this paper is to analyze and validate the status of the 2012 prosthodontics education curriculum in Korean dental schools, and to suggest future direction. Materials and methods: A survey was completed by all the 11 dental schools in South Korea. Results: The number of students, age, sex, credits for prosthodontics lecture and practice courses, evaluation method before senior students' clinical practice, modalities for minimum requirement for graduation, beginning and finishing timing of clinical practice and faculty personnel involved in the education varied among the dental schools. Conclusion: High-quality educators leading an expanded teaching personnel are required, education hours must be increased and efficient curriculum must be organized to improve the prosthodontics education.

Kinetic Characterization of an Iron-sulfur Containing Enzyme, L-serine Dehydratase from Mycobacterium tuberculosis H37Rv (Mycobacterium tuberculosis H37Rv로부터 유래된 철-황 함유 효소인 L-세린 탈수화효소의 동력학적 특성)

  • Han, Yu Jeong;Lee, Ki Seog
    • Journal of Life Science
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    • v.28 no.3
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    • pp.351-356
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    • 2018
  • L-Serine dehydratase (LSD) is an iron-sulfur containing enzyme that catalyzes the conversion of L-serine to pyruvate and ammonia. Among the bacterial amino acid dehydratases, it appears that only the L-serine specific enzymes utilize an iron-sulfur cluster at their catalytic site. Moreover, bacterial LSDs are classified into four types based on structural characteristics and domain arrangement. To date, only the LSD enzymes from a few bacterial strains have been studied, but more detailed investigations are required to understand the catalytic mechanism of various bacterial LSDs. In this study, LSD type II from Mycobacterium tuberculosis (MtLSD) H37Rv was expressed and purified to elucidate the biochemical and catalytic properties using the enzyme kinetic method. The L-serine saturation curve of MtLSD exhibited a typically sigmoid character, indicating an allosteric cooperativity. The values of $K_m$ and $k_{cat}$ were estimated to be $59.35{\pm}1.23mM$ and $18.12{\pm}0.20s^{-1}$, respectively. Moreover, the plot of initial velocity versus D-serine concentration at fixed L-serine concentrations showed a non-linear hyperbola decay shape and exhibited a competitive inhibition for D-serine with an apparent $K_i$ value of $30.46{\pm}5.93mM$ and with no change in the $k_{cat}$ value. These results provide insightful biochemical information regarding the catalytic properties and the substrate specificity of MtLSD.

Comparative Study About Academic Thoughts of Xu Lingtai and Yoshimasu Todo (II) - Analysis of the Cause of Similarities and Differences in their Academic Thoughts - (서영태(徐靈胎)와 길익동동(吉益東洞)의 학술사상 비교 연구 (II) - 학술 사상이 같고 다른 원인에 대한 분석 -)

  • Yoon, Cheol-Ho;Huang, Huang
    • The Journal of Internal Korean Medicine
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    • v.32 no.1
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    • pp.87-99
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    • 2011
  • In the 18th century, Xu Lingtai (徐靈胎) and Yoshimasu Todo (吉益東洞) were medical revolutionaries. They emphasized researches about synthesis of formulae, efficacy of medication and observation and then classification of clinical phenomena, so they assumed a modern scientific character. But, there were clear differences between their academic thoughts. In this paper, we examine the causes of difference in three fields, i.e. traditional culture, viewpoints of talented people and academic personality. The first, difference was due to traditional culture. Chinese medicine has a long history and heavy traditional culture. Yin-Yang (陰陽) theory, Five Phase(五行) theory, Viscera and Bowels (臟腑) theory and Meridian and Collateral (經絡) theory stemmed from everyday practice, and Chinese people learn these theories from experience and observation. From the standpoint of Chinese people, particularly scholarly doctors [儒醫] such as Xu Lingtai, it was easy to debate medical theories. In contrast, Japanese traditional culture didn't have as long a history as China. Thus as a necessity, it was harder to disseminate traditional Chinese medicine theories in Japan. Yoshimasu Todo simplified it by cutting out the superfluous traditional Chinese medicine theory, so at that time it must have been shocking to the Japanese medical world's trends. The second, difference was due to viewpoints of talented experts. From the standpoint of Xu Lingtai, above all, medicine is just a learning, only a kind of technique, even more not a means of living. Xu Lingtai was concerned with the appearance of very talented experts such as 'great man' (偉人), and 'exceptional man' (奇士) who carried out medical research. Instead of cultivating a few talented people, Yoshimasu Todo tried to produce a large number of clinicians quickly who could treat ordinary people. The third was due to personality difference. As Xu Lingtai threw away Confucianism and studied medicine in his youth, although he had a critical attitude, he was always mild-mannered. Yoshimasu Todo always had a clearly critical and rebellious nature. Personality influenced their literary spirit and learning style, so although both advocated reactionism, the academic thought of Xu Lingtai was reformative and mild, while that of Yoshimasu Todo was revolutionary and fierce. Xu Lingtai and Yoshimasu Todo had considerably similar research domains and academic thought, so it is proper for them both to serve as examples for making a comparative study of medical history in China and Japan in 18th century.