• 한국임상약학회지
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• 제10권3호
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• pp.130-139
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• 2000

This study is intended to set the criteria for the classification of prescription and non-prescription drugs, and classify hospital pharmacy formulations according to the criteria. 717 hospital pharmacy formulations were collected ken the Center for review and evaluation of health insurance, and national provincial offices. Hospital pharmacy formulations were evaluated based on the 'Guidelines on the Hospital Pharmacy Formulations (Notification No. 2000-46)'by the Ministry of Health and Welfare. Drug classification advisory committee was composed of twelve medical and pharmaceutical specialists, and suggested opinions on the drug classification. Among 717 formulations, 651 drugs $(90.8\%)$ satisfied the basic conditions for the hospital pharmacy formulations. 312 formulations $(43.5\%)$ were classified as drugs for the disinfection and tests. For the rest of them, 231 formulations were classified as prescription drugs whereas 108 drugs were as non-prescription drugs. 56 non-prescription drugs were included as hospital formulations, because there were no therapeutic alternatives. Iu sum 599 drugs $(83.5\%)$ were suggested as hospital pharmacy formulations. The study also recommends pharmaceutical companies to produce drugs of limited commercial value, and doctors to change their unique prescribing behavior in order to prevent the abuse of hospital pharmacy formulations.

• 음성과학
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• 제9권1호
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• pp.185-192
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• 2002

This study classifies Korean syllables into various types and investigates the distribution of syllables by each type. Korean syllables are classified into four or eight types. In this study, they are classified into thirty-two types based on character combination in order to evaluate the intelligibility of Korean synthetic syllables. Among those Korean syllables derived from the possible combinations of Korean characters, only currently used syllables were selected. Based on this classification and distribution, representative and diagnosable testing materials can be made. These testing materials can be applicable to intelligibility tests of Korean synthetic syllables.

• 한국실내디자인학회:학술대회논문집
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• 한국실내디자인학회 2001년도 춘계학술발표대회 논문집
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• pp.121-127
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• 2001

An unified measure of user interface efficiency and aesthetics for cyber museum is proposed. First, general structure of cyber museum is discussed and hierarchical analyses are done for sample sites. Usability tests based on the hierarchical analyses yield statistics of user access frequency and persistency for each page, on which access probability is deduced. Second, visual occupancy, a measure of efficiency of user interface element based on access probability is defined. The hierarchical statistics of visual occupancy can be an index for characterization and classification of cyber museums. Examples are provided.

• 임상간호연구
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• 제18권3호
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• pp.354-367
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• 2012

Purpose: This study was done to verify validity and reliability of a neonatal patient classification system (NeoPCS-1). Methods: An expert group of 8 nurse managers and 40 nurses from 8 Neonatal Intensive Care Units in Korea, verified content validity of the measurement using item level content validity index (I-CVI). The participants were nurses caring for 469 neonates. Data were collected from November 11 to December 14, 2011 and analyzed using descriptive statistics, ANOVA, intraclass correlation coefficient, and K-cluster analysis with PASW 18.0 program. Results: Nursing domains and activities included 8 items with 91 activities. I-CVI was above .80 in all areas. Interrater reliability was significant between two raters (r=.95, p<.001). Classification scores for participants according to patient types and nurses' intuition were significantly higher for the following patients; gestational age (${\leq}29$ weeks), body weight (<1,000 gm), and transfer from hospital. Six groups were classified using cluster analysis method based on nursing needs. Patient classification scores were significantly different for the groups. Conclusion: These results show adequate validity and reliability for the NeoPCS-1 based on nursing needs. Study is needed to refine the measurement and develop index scores to estimate number of nurses needed for adequate neonatal care.

• Journal of Pharmaceutical Investigation
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• 제36권3호
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• pp.161-167
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• 2006

The objective of this study was to investigate the dissolution patterns of variety of orally administered drug products available on the market. It aimed to understand their dissolution behaviors on the basis of the biopharmaceutics classification system (BCS) concept. On the tenets of BCS, several active pharmaceutical ingredients were selected: fluoxetine hydrochloride (class I), naproxen sodium (class ll), pyridostigmine bromide (class III), furosemide (class IV) and simvastatin (class IV). Typical dissolution media used in this study were pH 1.2, pH 4 & 6.8 phosphate buffers, and water. In cases, particular dissolution media specified in the KP and/or USP were used. Dissolution patterns of fluoxetine hydrochloride and pyridostigmine bromide products were characterized by their rapid release In addition, their dissolution characteristics were relatively unaffected by the type of a dissolution medium. Similar dissolution patterns were observed with pH 1.2, pH 4 & 6.8 phosphate buffers and water. By sharp contrast, poor dissolution patterns were noticed with naproxen sodium products, when pH 1.2 and pH 4 phosphate buffer were used. Improvements in its dissolution were achieved by switching the dissolution media to pH 6.8 phosphate buffer or water. Unsatisfactory dissolution data also were observed with a simvastatin product, when it was subject to dissolution tests by use of a surfactant-free pH 1.2, pH 4 & 6.8 phosphate buffers and water. All the release patterns reported in this study were best understood when BCS concepts were implemented. Our results demonstrated that a BCS-based drug classification should be considered first to choose a dissolution test/method and set up dissolution specification.

• 한국공간구조학회논문집
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• 제16권2호
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• pp.55-60
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• 2016

The Membrane structure has a number of problems in the application of a fireproof code based on general buildings codes. Thus, the fireproof code of membrane structure is necessary to activate the construction of the membrane structure. Because it requires a systematic classification of fire retardant and flame proof performance of membrane material. Fire retardant and flame proof tests are conducted on membrane materials mostly used in current construction to propose the fire and flame retardant performance criteria of membrane materials. Fire and flame retardant tests results, PTFE membrane material with the glass fiber fabric have a limit-combustible performance. PVDF membrane material with the polyester fabric does not ensure the fire retardant performance, but this membrane material has the flame retardant performance of a thick fabric. Also, ETFE does not ensure the fire retardant performance, but this membrane material has the flame retardant of a thin fabric.

• 한국지반환경공학회 논문집
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• 제23권1호
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• pp.15-23
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• 2022

This paper presents the results of full-scale load tests performed frictional anchors to various lengths at several sites in Korea. Various rock types were tested, ranging from highly weathered shale to sound gneiss. In many tests, rock failure was reached and the ultimate loads were recorded along with observations of the shape and extent of the failure surface. Laboratory tests were also conducted to investigate the influence of the corrosion protection sheath on the bond strength. Based on test results, the main parameters governing the uplift capacity of the rock anchor system were determined. By evaluation of the ultimate uplift capacity of anchor foundations in a wide range of in situ rock masses, rock classification suitable for structural foundation was developed. Finally, a very simple and economical design procedure is proposed for rock anchor foundations subjected to uplift tensile loads.

• 대한의용생체공학회:의공학회지
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• 제32권2호
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• pp.134-143
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• 2011

The selection of meaningful clinical tests and its reference values from a high-dimensional clinical data with imbalanced class distribution, one class is represented by a large number of examples while the other is represented by only a few, is an important issue for differential diagnosis between similar diseases, but difficult. For this purpose, this study introduces methods based on the concepts of both discernibility matrix and function in rough set theory (RST) with two discretization approaches, equal width and frequency discretization. Here these discretization approaches are used to define the reference values for clinical tests, and the discernibility matrix and function are used to extract a subset of significant clinical tests from the translated nominal attribute values. To show its applicability in the differential diagnosis problem, we have applied it to extract the significant clinical tests and its reference values between normal (N = 351) and abnormal group (N = 101) with either cholecystitis or cholelithiasis disease. In addition, we investigated not only the selected significant clinical tests and the variations of its reference values, but also the average predictive accuracies on four evaluation criteria, i.e., accuracy, sensitivity, specificity, and geometric mean, during l0-fold cross validation. From the experimental results, we confirmed that two discretization approaches based rough set approximation methods with relative frequency give better results than those with absolute frequency, in the evaluation criteria (i.e., average geometric mean). Thus it shows that the prediction model using relative frequency can be used effectively in classification and prediction problems of the clinical data with imbalanced class distribution.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1992년도 한국자동제어학술회의논문집(국제학술편); KOEX, Seoul; 19-21 Oct. 1992
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• pp.514-519
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• 1992

To make an accurate retrieval of the proportion of each category among mixed pixels (Mixel's) of a remotely sensed imagery, a maximum likelihood estimation method of category proportion is proposed. In this method, the observed multispectral vector is considered as probability variables along with the approximation that the supervised data of each category can be characterized by normal distribution. The results show that this method can retrieve accurate proportion of each category among Mixel's. And a index that can estimate the degree of error in each category is proposed. AS one of the application of the proportion estimation, a method for image classification based on category proportion estimation is proposed. In this method all pixel in a remotely sensed imagery are assumed to be Mixel's, and are classified to most dominant category. Among the Mixel's, there exists unconfidential pixels which should be categorized as unclassified pixels. In order to discriminate them, two types of criteria, Chi square and AIC, are proposed for fitness test on pure pixel hypothesis. Experimental result with a simulated dataset show an usefulness of proposed classification criterion compared to the conventional maximum likelihood criterion and applicability of the fitness tests based on Chi square and AIC,

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권8호
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• pp.3725-3748
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• 2018

Text data distribution is often imbalanced. Imbalanced data is one of the challenges in text classification, as it leads to the loss of performance of classifiers. Many studies have been conducted so far in this regard. The proposed solutions are divided into several general categories, include sampling-based and algorithm-based methods. In recent studies, feature selection has also been considered as one of the solutions for the imbalance problem. In this paper, a novel one-sided feature selection known as probabilistic feature selection (PFS) was presented for imbalanced text classification. The PFS is a probabilistic method that is calculated using feature distribution. Compared to the similar methods, the PFS has more parameters. In order to evaluate the performance of the proposed method, the feature selection methods including Gini, MI, FAST and DFS were implemented. To assess the proposed method, the decision tree classifications such as C4.5 and Naive Bayes were used. The results of tests on Reuters-21875 and WebKB figures per F-measure suggested that the proposed feature selection has significantly improved the performance of the classifiers.