• The Journal of Pediatrics of Korean Medicine
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• v.37 no.4
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• pp.63-69
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• 2023

Objective This study aimed to compare two cases of hyperhidrosis treated with herbal medicines. Methods This study included two children with hyperhidrosis who visited Pusan National University Korean Medicine Hospital. One patient was treated with Okbyungpoong-tang gagam and the other with Daeshiho-tang. Visual analog scale (VAS) scores for symptoms were evaluated before and after treatment. The characteristics, symptoms, and progression of treatment of each patient were evaluated and compared. Results After treatment, the patients showed a remarkable improvement in their main symptoms, and their constipation was relieved. Conclusion This case study showed that hyperhidrosis in two children improved significantly with herbal medicine. Furthermore, herbal medicine was effective in improving the accompanying symptoms, including constipation.

• The Journal of Pediatrics of Korean Medicine
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• v.37 no.4
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• pp.34-52
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• 2023

Objective This study aimed to evaluate the effect of herbal medicines on transient hip synovitis (TSH) in children. Methods We searched 10 Korean, English, Japanese, and Chinese databases for studies published up to September 19, 2023. Randomized controlled trials (RCTs) evaluating the effect of herbal medicines on TSH levels in children were included. The Cochrane risk of bias was used to evaluate the quality of the studies. A meta-analysis was conducted according to outcome measurements, such as total effective rate (TER), visual analog score (VAS), time to pain relief, and hip joint mobility disorder disappearance time, using the Review Manager website. Results Eleven RCTs were included in this study. TER in the treatment group was significantly higher than in the control group. The duration of pain relief was significantly shorter in the treatment group than in the control group. The VAS score of the treatment group was significantly lower than that of the control group, although the statistical heterogeneity was substantial. The hip joint mobility disorder disappeared in the treatment group treated with external therapy, which was significantly shorter than in the control group. Regarding safety, two of the 11 studies reported that there were no adverse events. Conclusions Herbal medicines are effective in the treatment of TSH in children. However, the safety of herbal medicines should be carefully considered due to the lack of data.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.2
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• pp.494-497
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• 2006

A child with five delay, five ankylosis, five weakening needs to take herbal medicine for a long term. So safety, efficacy inspection for the long term usage of herbal medicine and mixed dose is needed because other medication or functional health foods, etc could be taken during this process. Operated liver function test before and after dosing herbal medicine to one hundred and sixty children who aided private oriental medicine located in Seoul, and measured the efficacy by comparing sleeping hours, morbidity, stamina, sanguineness, personality, digestion with the state before taking herbal medicine based on questionnaire done by the parents. Every children were under the limits, and there were no differences between boys and girls, and no notable differences according to family histories. There were positive results in efficacy inspection ordered as improvement in personality, stamina, sanguineness, decrease in morbidity, increase in appetite, digestion. No signs of disorder in liver function has been found during the dose of herbal medicine or simultaneous medicine, and shown promotion of health.

• The Journal of Pediatrics of Korean Medicine
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• v.37 no.4
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• pp.15-24
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• 2023

Objectives This study aimed to identify the current status and satisfaction with Korean medicine treatment and analyze the perceptions of parents about Korean medicine treatment in children. Methods A Web survey (Moaform) was conducted with 52 parents whose children used Korean medicine and 53 parents who did not. We investigated the reasons why the user group chose treatment and satisfaction with each treatment and why the non-user group did not choose the treatment. Results Children in the user group were frequently prescribed herbal medicines (decoctions) and acupuncture. However, they showed low satisfaction in terms of fear of acupuncture and dissatisfaction with the unique taste of herbal medicine. Non-user parents had a favorable opinion of Korean medicine, but had relatively negative perceptions about whether their children were willing to visit in the future. Conclusions Parents who used Korean medicine for their children had positive perceptions and trust in Korean medicine. However, those who did not use Korean medicine were concerned about the safety and potential harm of its application to their children.

• The Journal of Pediatrics of Korean Medicine
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• v.24 no.3
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• pp.26-32
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• 2010

Objectives: This study is to report a case of the paralytic strabismus with herbal medicine and acupuncture. Strabismus refers to the oculomotor muscles imbalance resulted from improper alignment of the visual axis of the two eyes. Our goal is to know the effectiveness and safety in children from oriental medicine. Methods: We treated the case by using herbal medicine, acupuncture, and etc. Results: We found that the case was recovered perfectly in short term(24days) without any side effects or complaints. Therefore, we try to apply this treatment in many children cases and to set as a guideline protocol to treat for children. Conclusions: The case showed proper oriental medical treatment is better choice for therapy than surgery or observation.

• The Journal of Pediatrics of Korean Medicine
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• v.35 no.3
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• pp.67-88
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• 2021

Objectives The purpose of this study is to analyze randomized clinical trials (RCTs) on traditional Chinese medicine to summarize its efficacy and safety for the treatment of functional gastrointestinal disorders (FGIDs) in children. Methods We searched literatures published up to March 19, 2021 using two Chinese electronic databases. Data regarding patients, interventions, results, and adverse events were extracted from RCTs of herbal medicine for children with FGIDs. Results A total of 34 RCTs were included: 16 trials on functional dyspepsia, 7 trials on functional constipation, 6 trials on functional abdominal pain, 4 trials on irritable bowel syndrome, and 1 trial on functional diarrhea. 26 of 29 trials that reported total effective rate, the treatment group showed a significant improvement compared to the control group. Most of other evaluation indicators, such as symptom score, symptom disappearance time, and recurrence rate also demonstrated statistically significant improvement. Of the 16 studies which reported safety, 5 studies reported no adverse reactions in either group, and 4 studies reported no statistically significant differences in the incidence of adverse events between two groups. Also, reported adverse events were mostly mild. Conclusions Herbal medicine may help improve symptoms of FGIDs in children. However, due to limited types of studies on sub-diseases of FGIDs and small sample sizes in each study, additional large scale clinical studies on various other FGIDs are necessary.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.2
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• pp.530-535
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• 2005

A Korean traditional herbal formular, Taeumbiman-tang(TBT), was based on Taeumjowi-tang, currently the most widely used herbal formula compound, and which is known to be safe and have a positive effect on adult obesity. TBT was given to obese children for thirty days, and was found to be clinically safe and effective. The subjects were children who had been admitted into the hospital to be treated for obesity, that had more than 20% relative body weight. Originally there were 19 subjects, but 5 dropped out of the experiment. There were 5 girls and 9 boys, whose average ages were $11.00\;{\pm}\;2.60$ years, average weight was $54.01\;{\pm}\;18.59\;kg$. As a pretest, all of the volunteers were examined for height, weight, blood pressure, pulse rate, EKG, and chest radiography. The subjects underwent interview, body measurement tests, blood tests, and safety tests under 8 hour fasting state. After 15 days of TBT intake, the safety tests and the interview were conducted. The interview, body measurement tests, blood tests, and safety tests were conducted again after the 30 day trial was completed. The short term effects of TBT on obese children is weight loss. It did not cause any significant changes in the subject's livers, hearts, and kidneys, and clinically dangerous side effects or withdrawal symptoms were not observed.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.37 no.1
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• pp.42-56
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• 2024

Objectives : The purpose of this literature review is to analyze herbal medicine's efficacy in pediatric otitis media. Methods : Six databases(Pubmed, CNKI, RISS, KISS, KCI, OASIS) were used to search randomized controlled trials related to pediatric otitis media until October 2023. Total nine studies written in Korean, English, Chinese, and German were selected and analyzed. Results : Recurrent otitis media was treated with Kami-hyunggyeyungyo-tang, Echinacea purpurea, and Sipjeondaebo-tang. For acute otitis media, Otovowen and Sopunghaedok capsule were administered, while Oryung-san, Chongyi-tang, and Changyija-san were used for otitis media with effusion. Glycyrrhizae Radix(甘草) and Cnidii Rhizome(川芎) were the most frequently used. Objective measures showed superior effects in the herbal medicine group for otoscopic examination, impedance test, audiometry, and fever. Sipjeondaebo-tang exhibited significant efficacy in recurrent otitis media treatment, possibly related to warming-interior medicine(溫裏藥) or blood-invigorating medicine(血分藥). Conclusion : Analyzing studies revealed herbal medicine's superiority for pediatric otitis media over conventional approaches.

• The Journal of Pediatrics of Korean Medicine
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• v.20 no.3
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• pp.105-116
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• 2006

Objectives: The purpose of this study is to investigate the present situation for oriental examination and treatment of ADHD by questionnaire. Methods : We surveied oriental clinics which publicized on internet that they run a clinic of ADHD and oriental university hospitals which had a department of Pediatrics or Neurophycholosy. Results : The number of responding that the period of actively attending upon treatment of ADHD children was less than 3 years was 9(60%). The number of responding that in these 3 months, the number of ADHD children visiting clinics were under ten was 8(53.3%). The number of responding that the average age of ADHD children visiting clinics were 7 to 10 years old were 10(66.7%). The number of responding that they assessed diagnosis of ADHD children were 7(46.7%). The number of responding that they assessed oriental medical examination to ADHD children were 9(60%). The number of responding that the most effective treatment to ADHD children was Herbal Medicine was 10(66.7%). The number of responding that the interval of treatment of ADHD was 1 to 3 months was 9(60%). Conclusions : Recently oriental medical treatments for ADHD has been attempted. Treatment methods were herbal medicine, acupuncture, parents education, etc. But further studies are needed.

• The Journal of Pediatrics of Korean Medicine
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• v.20 no.2
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• pp.35-44
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• 2006

Objective : As today obese children have increased rapidly in Korea, the interest has been much increased. And parents concern about the effect of Herbal Medication(HM) on gaining weight. Therefore we had a retrospective study HM and obesity for children. Method : We examined medical record of 38 patients who visited to Department of Pediatrics in 00 medical center from 2002 to 2006 and took HM. Their Hight, Weight, Obesity Index(OI) were estimated at two points: before and after HM treatment. And they were divided into two groups according to the HM type and analyzed for differences of OI. Result : There were no significant changes in 38 patients's OI before and after treatment. But only one case gained over weight(OI: 21.31). OI increased slightly after treatment but there were not statistically significance. OI according to the HM type had slightly difference but there were not statistically significance. There were no connections between HM type, the number of days taking HM and changes of OI. Conclusion : On the basis of this study, we thought there were no connections between HM and obesity for children. But this study's cases are small in number so more study is need.