• Title/Summary/Keyword: chemical ingredient

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A Study on the Surface Deterioration Evaluation of Epoxy Resin Coating as Anticorrosive Material of Concrete Water Tank Using Ozone($O_3$) (오존 정수처리 음용수조 구조물에 사용하는 에폭시 수지 방수.방식재의 표면특성 평가)

  • 오상근;강효진;곽규성
    • Proceedings of the Korea Concrete Institute Conference
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    • 2003.11a
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    • pp.513-518
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    • 2003
  • Recently, advanced systems for water treatment are introduced for water quality improvement. One of those systems is water treatment method using ozone($O_3$). For it has strong oxidizing energy, it is necessary to have materisl stability against $O_3$. In this paper, epoxy resin specimens using as anticorrosive material of concrete structure for drink water are used to serve as a material of deterioration evaluation. It is to be studied weight loss, surface corrosion of specimens, ingredient analysis of floating particle, a solute of chemical ingredient by way of accelerated ozone testing. As the results of experiment, specimen weight is decreased. The surface of specimen is eroded heavily and showed a loss of gloss and floating particle, and in the stability for drinking water, harmful ingredient is not detected in the water.

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Metabolismus von 14C-Chlorsulfuron in Verschieden Empfindlichen Kulturpflanzen und Unkrautern (감수성(感受性)이 다른 작물(作物)과 잡초(雜草)에 있어서 Chlorsulfuron 의 대사작용(代謝作用))

  • Kang, Byeung-Hoa
    • Korean Journal of Weed Science
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    • v.4 no.2
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    • pp.115-124
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    • 1984
  • Chlorsulfuron (chemical name : 2-Chloro-N-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-aminocarbonyl-benzenesulfonamide) is a herbicidally active ingredient which shows effect against susceptible weeds already at such low rates like 5-20g active ingredient per hectare. In the here reported trials metabolism in several sensitive cultivated plants and weeds have been analysed using ^{14}C-labelled active ingredient. The uptake of chlorsulfuron by leaves or the root system is good in all plants species, and translocation takes place either symplasmatically or apoplasmatically. Metabolism takes place in all investigated plant species by development of hydrophile suhstances in roots and shoots. Decomposition of chlorsulfuron in roots and shoots of tolerant species (Triticum aestivum and Hordeum vulgare) to polare substances takes place quantitatively faster and quicker than in susceptible species (Beta vulgaris and Matricaria chamomilla).

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Glucanhydrolase from Lipomyces starkeyi KSM 22 as Potential Mouthwash Ingredient

  • Kim, Doman;Ryu, Su-Jin;Son, Eun-Ju;Chung, Hyun-Ju;Kim, Seung-Heuk;Kim, Do-Won;Day, Donal-F.
    • Journal of Microbiology and Biotechnology
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    • v.12 no.6
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    • pp.993-997
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    • 2002
  • A glucanhydrolase (a DXAMase exhibiting both dextranolytic and amylolytic activities) from Lipomyces starkeyi KSM 22 hydrolyzed polysaccharides having ${\alpha}-(1{\rightarrow}3)-,\;{\alpha}(1{\rightarrow}4)-,\;and\;{\alpha}-(1{\rightarrow}6)$-D-glucosidic linkages. The oral hygiene benefits of DXAMase-containing mouthwash were examined in relation to human experimental gingivitis during a 3-week period without brushing. The DXAMase-treated group exhibited a lower increase in plaque accumulation and gingival index score than the chlorhexidine-treated group. The DXAMase-treated group also showed less tongue accumulation, bad taste, and tooth staining, thus indicating a positive role for DXAMase as an antiplaque agent ingredient.

Antioxidant Activity and Whitening Efficacy of Makgeolli Fractions (막걸리 분획물의 항산화활성 및 미백효능)

  • Park, Kyung-won;Kwak, Da-hee;Kwon, Hye-Jin
    • Journal of Digital Convergence
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    • v.15 no.10
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    • pp.571-577
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    • 2017
  • This study aimed at evaluating the potential of makgeolli, which is widely consumed as beverage, as a functional cosmetic ingredient, based on analyses on its antioxidant activity and tyrosinase activity inhibitory effect. The sample was extracted by concentrating the suspension obtained after adding MeOH (3 L) to the residue of a commercial makgeolli and then adding EtOAc (3 L) to the concentrate, which was subjected to fractionation. The upper layer of the fractions was used as the final sample. In MTT assay assessments, no cytotoxicity was observed at a concentration range of 10 to $1,000{\mu}g/mL$; the antioxidant activity of the extract showed a concentration-dependent tendency and it had a high activity with an $EC_{50}$ of 7.008 mg/mL. Also, in a tyrosinase activity inhibitory effect assessment, the extract showed an $IC_{50}$ value of 39.22 mg/mL. These results confirmed that this sample has potential as a functional cosmetic ingredient.

The Risk Assessment of Runway Reaction in the Process of Fridel-Crafts Acylation for Synthesis Reaction (화합물 합성반응 중 Fridel - Crafts Acylation 공정에서의 폭주반응 위험성평가)

  • Lee, Kwangho;Kim, Wonsung;Jun, Jinwoo;Joo, Youngjong;Park, Kyoshik
    • Journal of the Korean Society of Safety
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    • v.36 no.3
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    • pp.24-30
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    • 2021
  • Heat is generated during the synthesis and mixing process of chemical compounds due to a change in activation energy during the reaction. A runaway reaction occurs when sufficient heat is not removed during the heat control process within a reactor, rapidly increasing the temperature, reaction speed, and rate of heat generation inside the reactor. A risk assessment was executed using an RC-1 (Reaction Calorimeter) during Friedel-Crafts acylation. Friedel-Crafts acylation runs the risk of rapid heat generation during Active Pharmaceutical Ingredient (API) manufacturing; it was used to confirm the risk of a runaway reaction at each synthesis stage and during the mixing process. This study used experimental data to develop a safety efficiency improvement plan to control the risks of runaway and other exothermic reactions, which was implemented at the production site of a chemical plant.

Chemical composition of cassava-based feed ingredients from South-East Asia

  • Natalia S. Fanelli;Leidy J. Torres-Mendoza;Jerubella J. Abelilla;Hans H. Stein
    • Animal Bioscience
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    • v.36 no.6
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    • pp.908-919
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    • 2023
  • Objective: Information about the chemical composition of cassava-based feed ingredients is needed to accurately formulate animal diets. A study was conducted to determine the chemical composition of cassava-based feed ingredients and to test the hypothesis that there is variation in chemical composition among cassava products originating from different South-East Asian countries. Methods: Sources of dried peeled and unpeeled cassava roots, cassava chips, cassava meal, high-ash cassava meal, and cassava residue were used. All samples were analyzed for dry matter, gross energy, nitrogen, amino acids (AA), acid-hydrolyzed ether extract (AEE), ash, minerals, total starch, insoluble dietary fiber, and soluble dietary fiber. Samples of peeled and unpeeled cassava roots, cassava chips, and cassava meal were also analyzed for sugars. Results: High-ash cassava meal had greater (p<0.05) dry matter and ash, but lower (p<0.05) total starch and gross energy than all other cassava products. Peeled cassava roots, unpeeled cassava roots, and cassava chips had greater (p<0.05) total starch than the other cassava-based ingredients. Cassava residue had greater (p<0.05) concentrations of lysine, insoluble dietary fiber, and soluble dietary fiber compared with the other cassava products, but tryptophan and glutamic acid were greater (p<0.05) in peeled cassava roots, cassava chips, and cassava meal samples compared with the other ingredients. Concentration of most minerals was greater (p<0.05) in high-ash cassava meal than in the other cassava products. Conclusion: Cassava-based ingredients sold as peeled roots, unpeeled roots, chips, or meal have chemical compositions that are not different from each other, and peeling has little impact on chemical composition. High-ash cassava meal has lower nutritional quality compared with other cassava products due to low starch and gross energy. The high fiber content in cassava residue makes this ingredient more suitable for ruminants and sows than for younger pigs or poultry.

Hazard Evaluation of Runaway Reaction in Deboronation Process Using H2O2 in DIET Synthesis of Pharmaceutical Raw Material (의약품 원료 DIET 합성 중 H2O2를 이용한 붕소제거 반응공정에서의 폭주반응 위험성 평가)

  • Kim, Won Sung;Lee, Keun Won
    • Journal of the Korean Institute of Gas
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    • v.22 no.4
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    • pp.49-54
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    • 2018
  • In the Active Pharmaceutical Ingredient(API) manufacturing company, since the product is produced by the chemical reaction, fire and explosion are frequently occurred in the process of inputting the raw powder as the chemical reaction stage. There are not many studies on safety measures through analysis of cause of accident in the actual chemical reaction stage. In this study, we investigated the heat flow in the boron removal reaction process to investigate the risk in the chemical reaction stage. The study reaction process was performed by using the reaction calorimeter for the products synthesized at the actual raw material in pharmaceutical factory. The risk was estimated by comparing the maximum temperature of the synthesis reaction, which can generate heat due to the failure of cooling in the actual manufacturing process, and the technical temperature. These results are applied to commercial manufacturing sites and safety measures to control the risk of runaway reaction due to reaction heat are suggested.

A Study on Anti-oxidative Activity of the Lithospermum Erythrorhizon Extracts for Application as a Cosmetic Ingredient

  • Park, Hee-Jeong;Lee, Ki-Young
    • Korean Journal of Plant Resources
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    • v.26 no.3
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    • pp.403-409
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    • 2013
  • This study has assessed the anti-oxidative activities and cytotoxic effects of Lithospermum erythrorhizon ethanol extract and measured the effects of tyrosinase inhibition activities with a goal of estimating the usage of the medicinal plant as an ingredient of cosmetics. First, to perform a basic test on the extract, pH and UV-spectrum were measured. According to the measurement, the extract had control functions at pH 5.5, and maximum absorbance occurred at 530nm. In particular, DPPH (1-1-diphenyl-2-picryl-hydrazyl)-inhibiting activity (IC50) and polyphenol content were 149.81 ${\mu}g/mL$ and $51.28{\pm}2.52$ mg/mL respectively. In addition, as extract concentration increased, tyrosinase inhibition activities improved as well. In raw 264.7 cell-based MTT assay, cell survival rates were 98% at 1000 ppm and 153% at 100 ppm. Therefore, it's been confirmed that there is almost no cytotoxin. According to the test results above, it appears that the Lithospermum erythrorhizon ethanol extract would be effective in anti-oxidation and application as a cosmetic ingredient.

Studies on Decolorization Process for rhEGF as Cosmetic Ingredient

  • Zhao Xiao-wei;Xu Zhi-nan;Zhou Mao-hong;Cen Pei-lin
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.10 no.3
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    • pp.236-241
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    • 2005
  • A decolorization process using ion exchange chromatography was developed to refine rhEGF as a cosmetic ingredient. A macroreticular resin (D314) was selected, with respect to its high decolorization rate and recovery yield of rhEGF, and the operational conditions of the decolorization process optimized. The optimum conditions were as follows: the rhEGF effluent was ion exchanged at a flow rate of 60.0mL/h, with an effluent pH 5.0, using a chromatographic column (i.d. 16mm) packed with D314, with a 7.5cm in bed height. The decolorization process was carried out under the optimum conditions, and halted when the effluent volume reached 350mL, giving a decolorization rate and recovery yield of rhEGF higher than 67 and $80\%$, respectively. When the decolorization rate exceeded $67\%$, the final product turned out to be white or light yellowish, which was to the satisfaction of the cosmetic standard.