• Title/Summary/Keyword: challenge test

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Health Promoting Life style, Hardiness and Gender Role Characteristics in Middel-Aged Women (중년여성의 건강증진 생활방식, 강인성 성역할 특성의 관계)

  • Suh, Yeon-Ok
    • Women's Health Nursing
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    • v.2 no.1
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    • pp.138-157
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    • 1996
  • Recently, there has been increase perception of health promotion with development of the economic state and science. Individual's responsibility and psychosocial factors have impacted on the individual's lifestyle. Health promotion can be maintained or improved through changes of lifestyle of individuals. Also, there has been supported results of health behavior health has been focused on menopausal symptom and reproductive organ. Until recently, little research has been available on the health or health care of midlife women. The purpose of this study was to explain relationship between health promoting lifestyle and hardiness, gender role characteristics. A total of 254 items of data were obtained from randomly selected subjects. The data collected from the interviews were analyzed using SPSS, yielding frequency, mean. t-test, ANOVA, Pearson Correlation, Stepwise multiple regression. The result of this study are as follows : 1) For the health promoting lifestyle, the mean score was 116.3, the highest score was nutrition(3.30) and interpersonal support(2.86), the lowest score was exercise(1.68). The highest subscale for the hardiness was committment(2.44). Also for the gender role characteristics was higher than median score(37.8). 2) There was a statistically difference the demographic variables. A total health promotion lifestyle was predicted by income and marriage satisfaction, hardiness was predicted by education, income, marriage satisfaction, support person and gender role characteristics was predicted by education. 3) With regard to the relationship among health promoting lifestyle, hardiness, gender role characteristics, the correlation coefficient between health promoting lifestyle and hardiness was r=-.48, p<.001. Also there were significant correlation between health promoting lifestyle and gender role characteristics(r=.22, p<.01), hardiness and gender role characteristics(r=-.39, p<.001). 4) A stepwise multiple regression analysis was done on the total health promoting lifestyle score using the demographic variables, hardiness subscale and gender role characteristics for independent variables. A total of 25% of the variance was explained inthe total health promoting lifestyle by the control, challenge and marriage satisfaction. In conclusion, hardiness and gender role characteristics were engaged in health promoting activity in midlife women. This study also provides new information about the health practices that midlife women report they practice. Therefore, nursing intervention to increase women's health have to be planed program that consider on the basis the results of this study.

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Analysis of Motor Carrier Crash Risk with Driver Hours of Service (화물자동차 운전자의 운행시간에 따른 사고위험도 분석)

  • Park, Sang-Woo
    • International Journal of Highway Engineering
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    • v.12 no.1
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    • pp.21-27
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    • 2010
  • Management of driver hours of service (HOS) for commercial vehicle operators has been a continual safety challenge. One of the more critical issues to government and motor carriers is fatigue and fatigue-related accidents. To reduce truck drivers’fatigue-related accident risk in other countries, the government issued the HOS regulations. However, korea government does not have any HOS regulations. The objective of this research gives the clues that korea should have the HOS regulation to reduce truck drivers’fatigue-related accident risk. This study examines the HOS regulation over other countries and conducts relative accident risk analysis using the real data from 3 freight companies. The data set includes 231 accident involved drivers and 462 non-accident drivers. Therefore, the size of the total data set is 693 drivers. One of the most important aspects of early studies of safety and HOS was the need to characterize continuous driving by using the notion of "survival". Subsequent research used a data replication scheme and logistic regression to capture the survival effect. This study uses time-dependent logistic regression. The test of significance between parameters indicates that the first three hours are almost the same risk. In the 10th hour of driving, the risk was more than 2.2times that in the baseline first hour. In conclusion, as driving time goes on, the crash risk increases.

Innate immune responses of common carp, Cyprinus carpio L. against antiviral activity inducers (항바이러스 활성 유도 물질에 대한 잉어의 선천성 면역 반응)

  • Cho, Mi-Young;Kim, Su-Mi;Kim, Eun-Jeon;Shon, Sang-Gyu;Kim, Jin-Woo;Park, Soo-Il
    • Journal of fish pathology
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    • v.20 no.2
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    • pp.189-200
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    • 2007
  • To investigate the innate immune response involved in early stage of anti-viral defence, carps were injected with UV-inactivated spring viraemia of carp virus (SVCV), poly inosinic:cytidylic acid (Poly I:C) and concanavalin A (Con A), respectively and examined lysozyme activity, serum complement activity and chemiluminescent (CL) response of leucocytes isolated from head kidney at 3 days post-injection. There was no significant difference in plasma lysozyme activities among all experimental groups. However, lysozyme activities of head kidney in the groups injected with antiviral activity inducers were significantly higher than those of the control injected with physiological saline. Bactericidal activities of serum of the groups injected with antiviral activity inducers were not significantly different from control group. However, the CL responses were significantly higher at lower dose of Poly I:C and Con A, whilst dose-dependent increase was shown in UV-inactivated SVCV-injected group. In the challenge test with 1×104 TCID50/fish of SVCV at 4 days post-injection, UV-inactivated SVCV- and Poly I:C-injected groups showed higher relative percent survival (RPS) than Con A-injected group. Furthermore, strong protection was observed in the group injected higher dose of Poly I:C although showed lower activities in lysozyme and CL response. These results suggested that Poly I:C might stimulate other factors belonging to non-specific immune system have induced protective immunity against the SVCV challenged.

Effects of Dietary Supplementation of Alga Mixtures (Hizikia fusiformis and Ecklonia cava) on Innate Immunity and Disease Resistance Against Edwardsiella tarda in Olive Flounder (Paralichthys olivaceus) (해조류(톳, 감태) 혼합물의 사료 내 첨가가 넙치의 선천성 면역과 질병저항성에 미치는 영향)

  • Kim, Sung-Sam;Jang, Ji-Woong;Song, Jin-Woo;Lim, Se-Jin;Jeong, Joon-Bum;Lee, Sang-Min;Kim, Kang-Woong;Son, Maeng-Hyun;Lee, Kyeong-Jun
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.42 no.6
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    • pp.614-620
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    • 2009
  • We report non-specific immune responses and its disease resistance against Edwardsiella tarda by alga mixture (HE; Hizikia:Ecklonia) in olive flounder for the first time. Five isonitrogenous (44% crude protein) and isocaloric (17.1 MJ $kg^{-1}$) diets were formulated to have 0%, 2%, 4%, 6% and 8% of the alga mixture. One of five experimental diets was fed triplicate groups of fish (30 fish/group) to apparent satiation in a flow through system. After a two week feeding, blood was sampled at 3, 6, 12, 24 h after the last feeding for a kinetic measurement of nitroblue tetrazolium (NBT) activity and healthy fish with similar sizes in each tank were selected and injected with 1 mL of E. tarda suspension ($1.0\times10^7$ CFU/mL) to evaluate the disease resistance of the fish. Dietary supplementation of alga mixtures resulted in significantly higher non-specific immune responses compared with the fish fed the control diet. The cumulative mortality was significantly lower in the fish groups fed alga mixture containing diets than control group in the challenge test with E. tarda. Therefore, the results in this study indicate that dietary supplementation of Hizikia and Ecklonia mixtures enhance the non-specific immune responses and a disease resistance of olive flounder.

Angiogenesis Markers in Breast Cancer - Potentially Useful Tools for Priority Setting of Anti-Angiogenic Agents

  • Keyhani, Elahe;Muhammadnejad, Ahad;Behjati, Farkhondeh;Sirati, Fereidoon;Khodadadi, Faranak;Karimlou, Masoud;Moghaddam, Fatemeh A.;Pazhoomand, Reza
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7651-7656
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    • 2013
  • Background: Breast cancer is the most common malignancy among women in both developed and developing countries. The burden is increasing in low-income and middle-income countries (LMCs) and threatens the public health of such societies. Introduction of expensive monoclonal antibodies to cancer treatment regimens poses a real challenge in the health systems of LMCs. Despite controversy of cost-effectiveness of bevacizumab in breast cancer, some studies indicate gain of patients from this drug. The present study aimed to propose a priority setting model for administration of anti-angiogenic agents in breast cancer via assessment of tumor angiogenesis by the microvessel density (MVD) method and associations with clinicopathological characteristics (including simultaneous mutations of TP53 and HER-2 genes). Materials and Methods: Age, axillary lymph nodes status, tumor size, stage and grade, estrogen and progesterone receptors status, HER-2/neu status (by immunohistochemistry and FISH test), TP53 mutation, Ki-67 (for proliferation assay) and CD34 (for angiogenesis assay) were assessed in 111 breast cancer patients. The molecular subtype of each tumor was also determined and correlations of simultaneous mutations of HER-2 and p53 genes with angiogenesis and other clinicopathological characteristics were evaluated. Results: There were significant associations between simultaneous mutations of HER-2 and p53 genes and all other parameters except tumor size. The degree of angiogenesis in the ERBB2 subtype was greater than the others. Younger patients showed a higher angiogenesis rate rather those older than 50 years. Conclusions: Our results demonstrated that patients with simultaneous mutations of HER-2 and p53 genes, those with ERBB2 molecular subtype and also younger women (often triple negative) seem more eligible for obtaining anti-angiogenic agents. These results suggest a model for priority setting of patients with breast cancer for treatment with anti-angiogenic drugs in LMCs.

The Effects of the Attractiveness of an Internet Shopping Mall and Flow on Affective Commitment

  • Kang, Sung-Ju;Kim, Jae-Yeong;Park, Young-Kyun
    • Journal of Distribution Science
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    • v.9 no.4
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    • pp.29-42
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    • 2011
  • With the many advantages of the internet, online shopping has become one of the fastest growing types of retail businesses. However, internet-based firms are much more firmly required to retain existing customers rather than secure new ones, and to make them revisit the site by strengthening trust and loyalty, thereby improving profits and outrivaling competitors. Commitment is an essential part of successful long-term relationships between buyers and sellers. Although commitments by both parties in an exchange can provide the foundation for the development of relational social norms, disproportionate commitments can lead to opportunism by the less committed partner. Moreover, flow, which is characterized by intense concentration and enjoyment, was found to be significantly linked with exploratory use behavior, which in turn was linked to the extent of computer use. The level of flow was, itself, determined by the individual's sense of being in control, and the level of challenge perceived in maneuvering a website. Website attractiveness goes hand in hand with the attractiveness of an internet shopping mall, and it can be conceptualized as the persuasive effectiveness of a message by the use of familiarity, favor, similarity, etc. It occurs when information receivers try to achieve self-satisfaction when they actually or emotionally identify themselves with an information source. This study investigates the relationship between the perceived system characteristics of an internet shopping mall and the loyalty of online consumers, and it examines how perceived website attractiveness and flow play mediating roles between the perceived system characteristics of an internet shopping mall and the affective commitment in the context of a clothes internet shopping mall. For these purposes, a structural model comprising several variables was developed. That model was tested with an analysis of moment structure (AMOS) using data from respondents who had purchased clothing through the internet during the past three months. In this model, the perceived system characteristics of an internet shopping mall, such as familiarity, reputation, uniqueness, positive emotions, self-efficacy, and interactivity, were proposed to affect the website's attractiveness and flow, and lead to a higher affective commitment over time. Thus, the perceived website attractiveness and flow were proposed as core mediating variables between perceived system characteristics and affective commitment. The results of a reliability test using Cronbach's Alpha, and a confirmatory factor analysis warranted using unidimensionality for the measures for each construct. In addition, the nomological validity of the measures was warranted from the results of a correlation analysis. The results of empirical analyses indicated that systematic attributes resulting in website attractiveness and user's characteristics, thereby triggering customers' flow, play a crucial role in inducing customers' affective commitment, and a user's characteristics are twice as important as systematic attributes in this study. Moreover, familiarity, reputation, and uniqueness all have a significant effect on website attractiveness, and the research showed that uniqueness took the first place, and that familiarity and reputation followed in order of magnitude. The fact that reputation was not the most important factor that affects the attractiveness of an internet shopping mall, with uniqueness or familiarity having a greater impact, suggests much deeper implications. Finally, positive emotion, self-efficacy, and interactivity all have a significant effect on customers' flow. In particular, the fact that positive emotion, compared to self-efficacy or interactivity, has much more impact on flow is very suggestive.

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On the dimensional stabilization of woods with treatment of Polyethylene Glycol-400 (폴리에치렌 글리콜-400에 의한 목재(木材)의 칫수안정화(安定化))

  • Cho, Nam-Seok;Jo, Jea-Myeong;Bae, Kyu-Yong
    • Journal of the Korean Wood Science and Technology
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    • v.3 no.1
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    • pp.3-15
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    • 1975
  • How to stabilize wood against shrinking and swelling in variable atmospheric moisture conditions is important to the wood-using industry and a challenge to research. Polyethylene glycol stabilize wood by bulking the fiber. PEG also serve as a chemical seasoning agent, suppress decay in high concentrations, and have slight effect on physical properties, gluing or finishing. The study designed to determine the effect of PEG-400 on the dimensional stabilization of local hardwoods for wood carvings that could supply a greatly expanding tourist trade and making curved furniture parts, lamp stands and other decorative objects, and possible gunstock. The species examined were 6 species, Seo-Namoo (Carpinus laxiflora), Cheungcheung-Namoo (Cornus controversa), Gorosae-Namoo (Acer mono), Karae-Namoo (Juglans mandshurica), Jolcham-Namoo (Quercusserrata) and Sanbud-Namoo (Prunus sargentii), used as block of 5cm thick radially to the grain, 7cm wide tangentially, and 70cm long parallel to the wood grain. All these test piecies were conditioned above the fiber saturation point before impregnation. The stabilization effects were determined for PEG-400 treated woods in a 50 percent solution for 20 days. The following conclusions were obtained. PEG retentions increased with treating time. It was more effective to treat at 60$^{\circ}C$ than at room temperature. In degree of PEG-400 impregnation on species, Cheungcheung-Namoo havinglow specific gravity had the highest retentions, 68.77% but the lowest, 56.33% was shown in Jolcham-Namoo with high specific gravity. Specific gravity of treated wood increased considerably with effectiveness of polymer loading. The increases in specific gravity were 5.36 to 13.16 percent. The highest was Jolcham-Namoo, the lowest Karae-Namoo. On the dimensional stability, a 40 percent of effectiveness of polymer loading was just as effective as 60 percent in reduction in water absorptivity (RWA), antishrinkage efficiency (ASE) and antiswelling efficiency (AE), and from over 60 percent they increased more rapidly. Also species response varied considerably. ASE was 30.12 to 69.97 percent tangentially and 27.86 to 56.37 percent radially, AE 34.06 to 73.76 percent tangentially and 30.11 to 70.12 percent radially, and RWA 42.31 to 65.32 percent. No differences in volume swelling among the 6 species were observed. Its values were ranged from 14.98 to 19.55 percent and also increased with PEG retentions. On the mechanical properties, the strengths very much decreased with PEG-400 loadings as shown in Figure 12; that were 11.41 to 22.90 percent in compression, 21.61 to 34.35 percent in bending and 22.83 to 36.83 percent in tensile strength. PEG retention in cell wall was less than 1 percent and the most of PEG were immersed in cell lumen. Except for Korae-Namoo, effectivenesses of polymer loading were as much high as 61.58 to 75.02 percent. This is believed to be due to the effect of PEG-400 on excellant dimensional stability of treated woods.

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Design and Experiments of Pneumatic Tactile Display for Haptic Interaction (햅틱 인터렉션을 위한 공기촉감 제시장치의 개발 및 실험 - 손끝 부착 형 공기촉감 제시장치의 개발 및 심리 물리학적 실험 -)

  • Kim, Yeong-Mi;Oakley, Ian;Ryu, Je-Ha
    • Journal of the HCI Society of Korea
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    • v.1 no.2
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    • pp.19-26
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    • 2006
  • This paper presents a novel pneumatic tactile display that can deliver some useful information. The air-jet display forms 5 by 5 arrays and features air nozzles with an external diameter of 2.4mm and internal diameter of 1.5 mm. In comparison with other tactile displays such as vibrotactile, there is little concrete psychophysical data relating to pneumatic displays, a fact which hinders their adoption. This paper addresses this challenge, and presents brief psychophysical studies examining localization rate, the two point threshold, stimulus intensity and the temporal threshold of cues produced by pneumatic air jets. Two groups of subjects were used in these studies, subsequently termed groups A and B. Both were comprised of eight participants. In the case of localization study we obtained 58.13% and 85.9% of localization rates each for dense display and sparse display. Two-points threshold test showed the length of gap between two air-jet stimuli which subjects can detect. However, it was formidable to find out precise temporal resolution of PTI owing to the limitation of capability of the pneumatic valves. Lastly, the results of stimulus intensity study suggest that by varying the size of a pneumatically created tactile stimulus, we can effectively vary its perceived magnitude.

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Effects of Dietary Probiotics Supplementation on Juvenile Olive Flounder Paralichthys olivaceus (치어기 넙치 사료내 생균제 첨가효과)

  • Jeong Chang-Wha;Choi Hee-Jung;Yoo Gwang-Yeol;Lee Seung-Hyung;Kim Young-Chul;OKorie Okorie Eme;Lee Jun-Ho;Jun Kyoung-Dong;Choi Se-Min;Kim Kang-Woong;Kang Yong-Jin;Kang Ju-Chan;Kong In-Soo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.39 no.6
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    • pp.460-465
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    • 2006
  • An 8-week feeding trial was conducted to investigate the effects of dietary supplementation with probiotics as a feed additive for Juvenile olive flounder (Paralichthys olivaceus). Three experimental diets supplemented with Bacillus polyfermenticus (BP), Bacillus licheniformis (BL), or Bacillus polyfermenticus plus Saccharomyces cerevisiae, (BP+SC) at $1.0{\times}10^7CFU/kg$ diet on a dry-matter basis were prepared. The basal diet was used as a control. After the 8-week feeding trial, the respiratory burst activity (NBT assay) of fish fed the BP + SC diet was significantly higher than that of fish fed the control diet. Fish fed the BP, BL and BP + SC diets had significantly lower cumulative mortality than did fish fed the control diet after the third day of the challenge test (P<0.05). However, there were no significant differences among fish fed the experimental diets in weight gain, feed efficiency, protein efficiency ratio, hematosomatic index, condition factor, survival rate, or Iysozyme activity. Results could suggest that dietary B. polyfermenticus, B. licheniformis, and B. polyfermenticus +S. cerevisiae enhance nonspecific immunity and disease resistance in juvenile olive flounder.

Determining Uses and Gratifications for the Mobile Games (이용 충족관점에서의 모바일게임 플레이어 유형과 특성 분석에 관한 연구)

  • Han, Kwang-Hyun;Lee, Han-Chul;Kim, Tae-Ung
    • Information Systems Review
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    • v.9 no.2
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    • pp.15-39
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    • 2007
  • Mobile games have emerged as the most innovative entertainment technology, adding new revenue streams, taking advantage of the potential of wireless applications and service offerings. Mobile games, like any other types of computer game, offer a unique value for users in providing an exciting digital experience in virtual worlds. In this paper, we attempt to investigate the demographic factors which play critical roles in determining the level of playing times; classify mobile gamers based on their motives for playing games; and empirically test differences in their demographic factors and mobile game usage. Statistical results show that significant differences in playing times exist, depending upon their age, gender, mobile device, mobile phone usage, mobile game experiences, and preferred games genres. Applying Factor analysis, we have identified Escape, Social interaction, Challenge and Competition, Fantasy, Diversion and Relaxation, Ease of Accessibility as key motivators for playing mobile games. Additional cluster analysis shows that the categorization of gamers, according to their usage habits and the key motivators for playing, can be made as follows: Multi-gamers, Communication-focused gamers and Mobile active-gamers. Further correlation of these grouping with socio-economic data shows the significant differences in gaming habits and patterns of mobile phone use.