• Journal of Korean Neurosurgical Society
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• v.29 no.10
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• pp.1316-1321
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• 2000

Objectives : The authors analyzed the surgical series of Cushing's disease to evaluate the proper treatment policy and to verify the possible prognostic factors. Material and Methods : Of 50 patients diagnosed as Cushing's disease and operated at Department of Neurosurgery of our institute between 1988 and 1999, 48 patients with available medical records were analyzed retrospectively. Mean follow-up period was 48 months(3 to 109 months). Preoperative diagnosis was made after evaluating the patients with multiple-stage endocrinological studies and 31 selective patients were evaluated with inferior petrosal sinus sampling(IPSS). Magnetic resonance imaging(MRI) and/or high resolution computerized tomography(CT) was done in all patients. A total of 51 transsphenoidal adenomectomy(TSA) were performed including 3 revision for initial surgical failure cases. Remission was decided on the basis of both endocrinological criteria and clinical status. Radiation and/or ketoconazole therapy were applied to failed cases. For the verification of prognostic factors, the authors evaluated the statistical significance of multiple variables over remission rate by chi-square test. Result : Sensitivity of IPSS for central localization was 93.5% which was better than that of MRI(87.5%). But for lateralization, it was 72.4% for IPSS versus MRI 90.5%. Success rate of TSA was 82%(42/51) and recurrence rate was 9%(4/48). When including adjuvant treatments for surgically failed cases, overall success rate was 89.6% and all of 3 reoperated cases(TSA) due to recurrence were successful. Significant complication occurred in 7.8%(4/51) after TSA including hypopituitarism, diabetes insipidus, and visual loss. Non-existence of tumor in MRI and prolonged symptom duration(>3 years) were significant prognostic factors. Conclusion : TSA can be considered as initial treatment for Cushing's disease. In surgically failed cases, multiple treatment modality may improve the overall outcome and repeated TSA for recurrent cases seem to provide similar success.

• Magazine of the Korean Society of Agricultural Engineers
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• v.17 no.4
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• pp.3980-3990
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• 1975

This study was carried out to develop a method of grain drying ststem that can be done by forcing the heated-air directly into the grains within the sack. The air duct was pushed into the central position of the grain-deposited sack and the heated-air was forced to flow in the radial direction. The system is referred here as the unit sack drying system. At a first step of this study, an air flow resistance tester was constructed to measure the resistance of air flow to grains in cooperated with some different sack materials, the sack materials, the tested were rice-straw bag, sack of polyethylene film, and jute sack In addition, unit sack drying system was constructed to investigate the drying characteristics of the dryer. on this dryer, two kind of terminal air ducts were attached and tested to examine its effects on uniform drying, and also, aseries of drying test was performed to trace the effect of increasing air flow rate on uniform drying. The results are as follows: 1) Resistance of air flow for each sack material was increased almost proportional to the increasing rate of air flow. Experimental data showed little significant differences of the air flow resistance among the materials. 2) From the comparison with air flow resistance of sack material and that of roughrice, it was indicated that airflow resistance of sack material was much higher than that of rice rough Therefore, in the unit sack drying sysle in which air flow is destined to face the sach material after leaving the grain, it was suggested that air flow would be inuniform to each part of grain within sack because of much higher air flow resistance of sack material than that of grain, and the fact would results inuniform grain drying. 3) Drying test on the unit sack drying system in cooperated with different type of terminal air ducts showed that high speed air is better for uniform drying than in high pressure. with the drying system which was assembled with the air ducts delivering higher speed air, there also involved a problem of significant inuniform drying. Therefore, any means to improve the inuniform drying should be undertaken for practical use. 4) A series of drying test with in creasing air flow rate resulted that increasing air flow rate in the unitsack drying system gave little effect on uniform drying, therefore, it is recommened to change its drying system for drying grain uniformly.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.14 no.3
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• pp.165-170
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• 1981

Recently an unknown microbial desease and some parasitic crustaceans are prevailing in the sea-weed farms of Uudaria pinnatifida along the south-eastern coast of Korea.(1) Green spots probably caused by the microbial pathogens were found on the fronds of Undaira Pinnatifide. Particularly they were densely distributed on the distal half of the fronds. The tissues of the green spot area rot off, and small holes with green colored margin are formed. The holes at the distal part of the fronds are enlarged and they finally coalesced each other. Then this process accelerates decaying of the distal ends of the fronds.. The fronds growing in the central part of the farms are usually severely damaged, whereas in the marginal area of the farm toward the open sea side the damage is less serious. An examination revealed that the deseased fronds bore a number of viable bacteria, $6.8\times10^5\;to\;1.2\times10^6$ per gram at $15^{\circ}C$, whereas the healthy fronds $1.1\times10^4$. Twenty-six kinds of colonies, 247 strains of bacteria, were isolated from deseased fronds, belonging to Moraxella, Achromobacter, Vibrio, Flavobacterium, Acinetobacter, Pseudomonas, etc. (2) Pinholes occurred in one series on the frond. They were probably caused by a harpacticoid copepod, Thalestris sp. Seven years ago when the disease was first found to occur the copepod was observed on the fronds from March of the year. Recently, however, they have been found as early as December of the previous year. (3) A gammarid amphipod, Ceinina iaponica, invades the pith of the midrib through holdfast of thalli. This rarely causes the longitudinal seperation of the entire frond through the midrib as they bore a tunnel in the pith. Sometimes holdfasts of tile heavy damaged thalli make the frond departed from the substrate.

• Journal of Korean Society of Steel Construction
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• v.20 no.2
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• pp.237-246
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• 2008

The cross-sections of continuous multi-span beams sometimes suddenly increase, or become stepped, at the interior supports of continuous beams to resist high negative moments. The three-dimensional finite-element program ABAQUS (2006) was used to analytically investigate the inelastic lateral-torsional buckling behavior of stepped beams subjected to pure bending moment and resulted in the development of design equations. The flanges of the smaller cross-section were fixed at 30.48 by 2.54 cm, whereas the width and/or thickness of the flanges of the larger cross-section varied. The web thickness and height of beam was kept at 1.65 cm and 88.9 cm, respectively. The ratios of the flange thickness, flange width, and stepped length of beams are considered analytical parameters. Two groups of 27 cases and 35 cases, respectively, were analyzed for double and single stepped beams. The combined effects of residual stresses and geometrical imperfection on inelastic lateral-torsional buckling of beams are considered. First, the distributions of residual stress of the cross-section is same as shown in Pi, etc (1995), and the initial geometric imperfection of the beam is set by central displacement equal to 0.1% of the unbraced length of beam. The new proposed equations definitely improve current design methods for the inelastic LTB problem and increase efficiency in building and bridge design. The proposed solutions can be easily used to develop new design equation for inelastic LTB resistance of stepped beams subjected to general loading condition such as a concentrated load, a series of concentrated loads or uniformly distributed load.

• Economic and Environmental Geology
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• v.40 no.1 s.182
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• pp.129-140
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• 2007

CFC(CFC-12, CFC-11 and CFC-113) analytical system for air and water was constructed using a customized purge and trap extraction device and a gas chromatograph with an electron capture detector. Sampling methods of air and water for CFCs were also established. The analytical system was experimentally optimized to result in reproducibilities of triplicates less than 2% for current air samples and less than 5% for groundwater samples with CFC-12 concentration of 160 to 180 pg/kg, and verified with respect to the CFC system in USGS, which showed analytical results were in agreement within 10%. CFCs in air were monitored at three sites over 19-month period in the central part of South Korea, and the result indicates no significant local sources of CFCs in those areas. For groundwater in Jeju Island, CFCs were measured over a year with a two-month interval. The time-series data showed seasonal fluctuations which could be interpreted by the effect of recharge pulse derived from large amount of rainfall during monsoon period with a few month delay, which indicates high permeability of basaltic rocks in Jeju Island.

• Tunnel and Underground Space
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• v.30 no.5
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• pp.473-483
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• 2020

This paper examines the vertical stress change concentrated on mine pillar which occurs due to the stress disturbance from opening excavation at room and pillar mine by FLAC3D, a finite difference method (FDM) software. The mesh size combination is decided with a careful consideration of relative error and run-time, then its performance is verified. A series of numerical analyses is conducted and the vertical stress at central pillar was observed for the test cases of 1×1 to 11×11 mine pillars, 40 m to 320 m depth with 40 m difference. The results show that the vertical stress of pillar approaches to the similar value with the value estimated by tributary area theory(TAT) when the development area (N_P) is increased or the height of overburden (H_OB) is decreased, while it is overestimated in the opposite case. Furthermore, it also represents that the vertical stress factor (VSF) converges to a specific value when the depth is increased whille keeping the development area identical.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.28 no.4
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• pp.337-346
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• 1992

Hydroacoustic surveys were conducted in the East China Sea, in the summers of 1990-1991 to investigate the distribution and migration behavior of fish, such as the diel changes in the distributions of fish, the thermoselection behavior of fish, and the fish reactions to a surveying vessel. The hydroacoustic observations were taken with a scientific echo sounder operating at 50kHz and a microcomputer-based echo processor. Fish samples were collected by bottom trawling and temperature was measured with a DBT system. The patterns of fish distributions were compared with the vertical profiles of water temperature. The results obtained can be summarized as follows: 1. The time series of hydroacoustic observations on the downward migration at dawn in the central region of East China Sea showed that the migration rate was 0.24 m/min. In this region, most of the fish collected by bottom trawling during the surveys were squid (Photologio edulis f. budo) and horse mackeral (Trachurus japonicus). 2. The hydroacoustic observations, which together associated with temperature data, indicated that squid and horse mackeral concentrated nocturally in a narrow vertical band of thermocline, particularly in summer when the survey region was strongly stratified. This result suggest that the nocturnal vertical distribution of these species evidently is controlled by temperature. 3. When the survey vessel, that is running at a speed of 11 knots, has suddenly stopped, the fish which concentrated beneath the transducer showed a strong avoidance reaction in the form of rapid downward migration. After a few minutes, the descending reaction disappeared and the fish slowly began the upward migration toward their original swimming positions. Trawl data suggest that the fish, which showed the avoidance reaction, was Liparis tessellatus.

• Journal of Korean Society for Geospatial Information Science
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• v.5 no.2 s.10
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• pp.131-144
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• 1997

Traffic jam densified day by day is phenomenon to occur lack of the road capacity in comparison with traffic density, but lack of the road cannot be concluded by main cause of traffic ism. Because the central function of a city would be concentrated upon the downtown and traffic demand would not be evenly distributed by the classification of an hour. Therefore, this study based on the fact that each driver will select the route generating traffic delay very low when path choice from origin to destination in travel plan estimating the quality of passage could be maintained the speed he want will approach to a characteristic grasp of a road, traffic, driver changing every moment by traffic-demand of road increased as a geometrical series with analysis a classification of a street, a intersection along the path on traffic density and highway capacity analysis the path using GIS techniques about complex street network, also will get the path of actual optimum for traffic delay trend creating under various condition the classification per a hour, a day of week and an incident through network such as analysis for traffic generation zone adjacent about street, intersection, afterward will expect the result increasing efficiency of the road-use through a good distribution of traffic by optimum-path choice, accordingly will prepare the scientific, objective, appropriate basis to decide the reasonable time of a road-widen and expansion through section analysis along a rate of traffic volume vs. road capacity.

• Atmosphere
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• v.24 no.4
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• pp.481-489
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• 2014

The Chugugi and Wootaek data of Gyeongsang-do (Dagu, Jinju, Goseong) were restored from "Gaksadeungnok", the governmental documents reported by the local government to the central during the Joseon Dynasty, and analyzed. The duration of the restored data represents 6 years for Daegu (1863, 1872, 1890, 1897, 1898, and 1902), 3 years for Jinju (1897, 1898, and 1900), and 2 years for Goseong (1871 and 1873). Total number of the restored data was 134, including 83 in Daegu, 25 in Jinju, and 26 in Goseong with the period ranging from March to September. The summer data from June to August accounts for approximately 50% (73 data), while the April data also shows relatively high number of 22, followed by September and March. Most data was collected from March to October, while this time winter data was not found even in October. The rainfall patterns using Chugugi data were investigated. First, the number of days with rainfall by annual mean showed 41 days in Daegu, 39 in Jinju, 33 in Goseong, respectively. In terms of the time series distribution of daily rainfall, the ratio between the number of occurrences with over 40 mm of heavy rainfall and the number of rainy days showed 14 times (8%) in Daegu, 24 (39%) in Jinju, and 4 (6%) in Goseong, respectively. The maximum daily rainfall during the period was recorded with 80mm in Jinju on August 24, 1900. The result of analyzing monthly amount of rainfall clearly indicated more precipitation in summer (June, July and August) with the relatively high records of 284 mm and 422 mm in April, 1872 and July, 1902, respectively, in Daegu, while Jinju recorded the highest value of 506 mm in June, 1898. When comparing the data with those observed by Chugugi in Seoul during the same period from "Seungjeongwonilgi", the monthly rainfall patterns in Daegu and Seoul were quite similar except for the year of 1890 and 1897 in which many data were missing. In particular, in June 1898 the rainfall amount of Jinju recorded as much as 506 mm, almost 4 times of that of Seoul (134 mm). Based on this, it is possible to presume that there was a large amount of the precipitation in the southern region during 1898. According to the calculated result of Wootaek data based on Chugugi observations, the unit of 1 'Ri' and 1 'Seo' in Daegu can be interpreted into 18.6 mm and 7.8 mm. When taking into consideration with the previous result found in Gyeonggi-do (Cho et al., 2013), 1 'Ri' and 1 'Seo' may be close to 20.5 mm and 8.1 mm, however, more future investigations and studies will be essential to verify the exact values.

• Interdisciplinary Bio Central
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• v.3 no.3
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• pp.10.1-10.8
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• 2011

Introduction: Hash functions are computer algorithms that protect information and secure transactions. In response to the NIST's "International Call for Hash Function", we developed a biological hash function using the computing capabilities of bacteria. We designed a DNA-based XOR logic gate that allows bacterial colonies arranged in a series on an agar plate to perform hash function calculations. Results and Discussion: In order to provide each colony with adequate time to process inputs and perform XOR logic, we designed and successfully demonstrated a system for time-delayed bacterial growth. Our system is based on the diffusion of ${\ss}$-lactamase, resulting in destruction of ampicillin. Our DNA-based XOR logic gate design is based on the op-position of two promoters. Our results showed that $P_{lux}$ and $P_{OmpC}$ functioned as expected individually, but $P_{lux}$ did not behave as expected in the XOR construct. Our data showed that, contrary to literature reports, the $P_{lux}$ promoter is bidirectional. In the absence of the 3OC6 inducer, the LuxR activator can bind to the $P_{lux}$ promoter and induce backwards transcription. Conclusion and Prospects: Our system of time delayed bacterial growth allows for the successive processing of a bacterial hash function, and is expected to have utility in other synthetic biology applications. While testing our DNA-based XOR logic gate, we uncovered a novel function of $P_{lux}$. In the absence of autoinducer 3OC6, LuxR binds to $P_{lux}$ and activates backwards transcription. This result advances basic research and has important implications for the widespread use of the $P_{lux}$ promoter.