• Title/Summary/Keyword: center of human body

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Particulate matter induces ferroptosis by accumulating iron and dysregulating the antioxidant system

  • Minkyung Park;Young-Lai Cho;Yumin Choi;Jeong-Ki Min;Young-Jun Park;Sung-Jin Yoon;Dae-Soo Kim;Mi-Young Son;Su Wol Chung;Heedoo Lee;Seon-Jin Lee
    • BMB Reports
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    • v.56 no.2
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    • pp.96-101
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    • 2023
  • Particulate matter is an air pollutant composed of various components, and has adverse effects on the human body. Particulate matter is known to induce cell death by generating an imbalance in the antioxidant system; however, the underlying mechanism has not been elucidated. In the present study, we demonstrated the cytotoxic effects of the size and composition of particulate matter on small intestine cells. We found that particulate matter 2.5 (PM2.5) with extraction ion (EI) components (PM2.5 EI), is more cytotoxic than PM containing only polycyclic aromatic hydrocarbons (PAHs). Additionally, PM-induced cell death is characteristic of ferroptosis, and includes iron accumulation, lipid peroxidation, and reactive oxygen species (ROS) generation. Furthermore, ferroptosis inhibitor as liproxstatin-1 and iron-chelator as deferiprone attenuated cell mortality, lipid peroxidation, iron accumulation, and ROS production after PM2.5 EI treatment in human small intestinal cells. These results suggest that PM2.5 EI may increase ferroptotic-cell death by iron accumulation and ROS generation, and offer a potential therapeutic clue for inflammatory bowel diseases in human small intestinal cells.

Brassiere Pattern Development Based on 3D Measurements of Upper Body - Focused on Women in Their 30's - (3차원 인체 계측 방법에 의한 상반신 체형을 고려한 브래지어 패턴 설계 - 30대를 대상으로 -)

  • Cho, Shin-Hyun;Kim, Mi-Sook
    • The Research Journal of the Costume Culture
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    • v.16 no.3
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    • pp.488-501
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    • 2008
  • The purpose of this study presents bra pattern using the 3D measurements of the upper body subject to women in their 30's. Brassieres available in the market are mostly designed for straight body shape and many women seem to have experienced bearing discomfort in a great extent as they grow older. Brassieres should be designed to cover diverse body types and the accurate measurement of body type and breast shape is needed to accomplish that. As for the study method, 3D human body types were analyzed with RapidForm 2006, and the upper-body types and breast shapes were statistically classified through technical statistics analysis, cluster analysis, t-test, variance analysis, and cross analysis. The wearing tests went through the comparison of the brassieres of three makers in the market and the experiment brassieres(first and second) and then the evaluations were made by the subjects, the outer appearance assessment by experts, and 3D measurements. The results of this study showed that the evaluation of experiment brassieres was excellent in every item, and the significant difference was found out particularly in the items of pressure, rear center, front center, breast underneath, adequate level by wing, and adequate level by armhole. According to the results of 3D evaluation, experiment brassieres had a highest point in fitness with no physical pressure at the wing part and no overall deviation at the cup part.

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Self-Perception of Body Image and Dieting Behaviors by Gender among High School Students in Gyeongbuk Province (경북 지역 고등학생의 성별에 따른 체형인식도 및 다이어트 행동에 관한 비교 연구)

  • Kim, Hyo-Chung;Kim, Mee-Ra
    • Journal of the East Asian Society of Dietary Life
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    • v.21 no.4
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    • pp.587-599
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    • 2011
  • The purpose of this study was to examine self-perception of body image and dieting behaviors by gender among high school students. The data were collected by a self-administered questionnaire during April, 2010, and analyzed by SPSS Windows V.18.0. The results were as follows. First, many respondents showed a desire to be underweight and regarded themselves as overweight, even though they had a normal BMI. Second, female respondents showed a higher level of concern about diet than male respondents. Third, male respondents received information about diet mostly from their family or friends, whereas female respondents received information from blogs, mini-homepages, or Kin-search on the Internet. Finally, female respondents showed a higher level of practice for fasting therapy than male respondents, whereas male respondents showed a higher level of practice for food therapy, drug therapy, oriental medicine therapy, and steam bath therapy. Therefore, high school should educate students to get right recognition and knowledge of diet.

Effect of Muscle Function and Muscular Reaction of Knee Joint in the Twenties on the Whole Body Vibration Exercise (전신진동운동이 20대 성인남녀의 슬관절 근기능과 근반응성에 미치는 영향)

  • Kang, Seung Rok;Jeong, Gu Young;Bae, Jong Jin;Min, Jin Young;Yu, Chang Ho;Kim, Jung Ja;Kwon, Tae Kyu
    • Journal of the Korean Society for Precision Engineering
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    • v.30 no.7
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    • pp.762-768
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    • 2013
  • This study investigated the effect of whole-body vibration on muscle function and muscular reaction in the knee joint. We recruited thirty healthy subjects and divided them into a training group, who experienced whole-body vibration, and a control group, who did not. The training group performed whole-body vibration exercises for 30 min per day, 3 days a week, for 8 weeks. We measured knee joint torque to estimate muscle strength and reaction, using BIODEX System 3. Knee joint peak torque and total work performed increased significantly in the training group, and muscle acceleration time decreased. These results suggest that stimulation by whole-body vibration can improve muscle strength and reaction by improving muscle tone and increasing blood temperature and flow speed in muscular fiber. Our results also indicate that 4 weeks of exercise with whole-body vibration is required to improve the reaction response, and six weeks to improve strength.

Evaluation of Saturday Nutrition Classes for Obese Elementary Students in Chungnam Province (비만 초등학생의 토요 영양 교실의 운영 효과 평가)

  • Park, Jin-Heui;Lee, Yong-Sook;Kim, Wan-Soo;Bae, Yoon-Jung;Lee, Ji-Eun;Choi, Yun-Hee;Jun, Ye-Sook;Choi, Mi-Kyeong
    • Journal of the East Asian Society of Dietary Life
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    • v.17 no.1
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    • pp.11-19
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    • 2007
  • This study was designed to evaluate Saturday nutrition classes for obese elementary students in Chungnam Province. Obesity index, nutrient intake, nutrition knowledge, nutrition attitude, and self-satisfaction of 36 obese elementary students were compared before and after attending nutrition classes every other Saturday for 3 months. The average age, height, weight, body fat, % body fat, and obesity index were 11.9 years, 145.5 cm, 53.3 kg, 24.5 kg, 45.7%, and 32.4%, respectively. Most of the subjects(94.5%) viewed themselves as fat. Sixty-three percent of children were discontent with their body-image. All answered that they have experience with weight control. The major methods of weight control were exercise and reduction of snacks. The mean serum cholesterol, blood glucose, GOT/GPT, and hemoglobin were 177.4 mg/dL, 90.4 mg/dL, 25.8/25.5 IU/L, 14.5 g/dL, respectively. After attending nutrition classes, the daily intakes of energy, plant protein, plant fat, carbohydrate, crude fiber, and cholesterol increased significantly. The scores for nutrition knowledge, nutrition attitude, and self-satisfaction also increased after nutrition classes, but there were no significant differences. Percent body fat decreased significantly after nutrition classes. In conclusion, nutrition education for elementary students is effective for the prevention and control of obesity. Further research is needed to develop a systematic program of nutrition education for obese children.

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Biomechanical Analysis of Human Stability According to Running Speed: A Comparative Analysis of Lyapunov Exponent and Coefficient of Variation Methods (달리기 속도에 따른 인체 안정성의 생체역학적 분석: 리아프노프 지수와 변이계수 방법의 비교 분석)

  • Ho-Jong Gil
    • Korean Journal of Applied Biomechanics
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    • v.33 no.1
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    • pp.34-44
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    • 2023
  • Objective: The purpose of this study was to examine the effects of increasing running speed on human stability by comparing the Lyapunov Exponent (LyE) and Coefficient of Variation (CV) methods, with the goal of identifying key variables and uncovering new insights. Method: Fourteen adult males (age: 24.7 ± 6.4 yrs, height: 176.9 ± 4.6 cm, weight: 74.7 ± 10.9 kg) participated in this study. Results: In the CV method, significant differences were observed in ankle (flexion-inversion/eversion; p < .05) and hip joint (internal-external rotation; p < .05) movements, while the center of mass (COM) variable in the coronal axis movements showed a significant difference at the p < .001 level. In the LyE method, statistical differences were observed at the p < .05 level in knee (flexion-extension), hip joint (internal-external rotation) movements, and COM across all three directions (sagittal, coronal, and transverse axis). Conclusion: Our results revealed that the stability of the human body is affected at faster running speeds. The movement of the COM and ankle joint were identified as the most critical factors influencing stability. This suggests that LyE, a nonlinear time series analysis, should be actively introduced to better understand human stabilization strategies.

An Analysis on Fashion Model Types

  • Kim, Jung-Won;Bae, Jong-Kil
    • Fashion & Textile Research Journal
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    • v.3 no.5
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    • pp.415-422
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    • 2001
  • Focusing on working with fashion show as fashion model in South Korea, this study was develop a fashion model typology based on specific model characteristics related demographics and body, job satisfaction/dissatisfaction factors. The survey was done through questionnaire and 194 fashion models were used in the data analysis. The statistical analysis used in this study were frequency, ${\chi}^2$-test, cluster Analysis, MANOVA. ANOVA and Duncan multiple range test. The results of this study were as follows: 1) The majority of sample were as follows: unmarried, college graduate and undergraduate, resident in the Seoul, 20 to 24 yrs old female with 175-177 cm, 52-54 kg, B-W-H (33-24-35 inch). 2) The types of fashion model were classified into 4 types: showing type, lack of professionalism type, matured professionalism type, dissatisfaction with job-environment type. The model segments were profiled on levels of various job related attitude factors, job satisfaction/dissatisfaction, model education, working condition, human relation, regulation discrimination, fashion show stage level, the job of model, body & clothing, and promising job. 3) There were significant differences found between their sex, academic background, guarantee, and in all factors in their job related attitude factors, job satisfaction/dissatisfaction, model education, working condition, human relation, regulation discrimination, fashion show stage level, the job of model, body & clothing, style promising job.

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Development of a Piezoelectric Micro-machined Ultrasonic Transducer for Photoacoustic Imaging that Accounts for the Added Mass Effect of the Acoustic Medium (음향 매질의 추가질량 효과를 고려한 광음향 영상용 초소형 압전 기반 초음파 트랜스듀서의 개발)

  • Ahn, Hongmin;Moon, Wonkyu
    • Journal of Sensor Science and Technology
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    • v.29 no.1
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    • pp.33-39
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    • 2020
  • Typically, photoacoustic images are obtained in water or gelatin because the impedance of these mediums is similar to that of the human body. However, these acoustic mediums can have an additional mass effect that changes the resonance frequency of the transducer. The acoustic radiation impedance in air is negligible because it is very small compared to that of the transducer. However, the high acoustic impedance of mediums such as the human body and water is quite large compared to that of air, making it difficult to ignore. Specifically, in a case where the equivalent mass is very small, such as with a micro-machined ultrasound transducer, the additional mass effects of the acoustic medium should be considered for an accurate resonance frequency design. In this study, a piezoelectric micro-machined ultrasonic transducer (pMUT) was designed to have a resonance frequency of 10 MHz in the acoustic medium of water, which has similar impedance as the human body. At that time, the resonance frequency of the pMUT in air was calculated at 15.2 MHz. When measuring the center displacement of the manufactured pMUT using a laser vibrometer, the resonance frequencies were measured as 14.3-15.1 MHz, which is consistent with the finite element method (FEM) simulation results. Finally, photoacoustic images of human hair samples were successfully obtained using the fabricated pMUT.

A Structural Analysis of Acupuncture & Moxibustion Points in the NaeGyeong Chapter of DongUiBoGam Using Text Mining (텍스트마이닝을 이용한 동의보감의 질병인식방식과 내경편 침구법 경혈 특성 분석)

  • Lee, Taehyung;Jung, Won-Mo;Lee, In-Seon;Lee, Hyejung;Kim, Namil;Chae, Younbyoung
    • Korean Journal of Acupuncture
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    • v.30 no.4
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    • pp.230-242
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    • 2013
  • Objectives : DongUiBoGam is a representative medical literature in Korea. This research intends to structurally grasp how DongUiBoGam understands the human body and review the methods of acupuncture and moxibustion in the NaeGyeong chapter of it using text mining. Methods : The structure of DongUiBoGam was analyzed with specific parts of the book that described contents, major premises of understanding the human body, and processes of treatment. We analyzed characteristics of each acupoints in a relationship with causes of diseases & symptoms in the NaeGyeong chapter using a Term Frequency - Inverse Document Frequency(TFIDF). Results : Three different categories of pattern identification(PI) were formed after structural analysis of DongUiBoGam. Every causes of diseases & symptoms were transformed according to the three categories of PI. After analyzing the relationship between acupoints and causes of diseases & symptoms, 114 acupoints were visualized with TFIDF values of three PI categories. Conclusions : The selection of acupoints in NaeGyeong chapter of DongUiBoGam were linked to causes of diseases & symptoms based on the three PI categories. Through visualization of bipartite relationships between acupoints and causes of diseases & symptoms, we could easily understand characteristics of each acupoint.

Worst-case Development and Evaluation for Vehicle Dynamics Controller in UCC HILS (차량자세제어 최악상황 개발 및 UCC HILS 시스템 기반 성능 평가)

  • Kim, Jin-Yong;Jung, Do-Hyun;Jeong, Chang-Hyun;Choi, Hyung-Jeen
    • Transactions of the Korean Society of Automotive Engineers
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    • v.19 no.6
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    • pp.30-36
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    • 2011
  • The current test methods are insufficient to evaluate and ensure the safety and reliability of vehicle system for all possible dynamic situation including the worst case such as rollover, spin-out and so on. Although the known NHTSA Sine with dwell steering maneuvers are applied for the vehicle performance assessment, they aren't enough to estimate other possible worst case scenarios. Therefore, it is crucial for us to verify the various worst cases including the existing severe steering maneuvers. This paper includes useful worst case based upon the existing worst case scenarios mentioned above and worst case evaluation for vehicle dynamic controller in simulation basis and UCC HILS. The only human steering angle is selected as a design parameter here and optimized to maximize the index function to be expressed in terms of both yaw rate and side slip angle. The obtained scenarios were enough to generate the worst case to meet NHTSA worst case definition. It has been concluded that the new procedure in this paper is adequate to create other feasible worst case scenarios for a vehicle dynamic control system.