• Title/Summary/Keyword: cell movement

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THE EFFECTS OF MECHANICAL STRESS ON CULTURED BONE CELL POPULATIONS (Mechanical stress가 골조직세포군에 미치는 영향)

  • Kim, Sang-Tae;Cha, Kyung-Suk
    • The korean journal of orthodontics
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    • v.24 no.1 s.44
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    • pp.105-114
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    • 1994
  • The movement of teeth during orthodontic treatment requires bone remodeling process of bone formation and bone resolution. To find out the changes occuring in the cell itself, mechanical stress was applied to the cell populations involved in the bone metabolism. Bone tissue cell populations were isolated from fetal rat calvaria and divided into OC and OB groups. Following results were obtained from measuring the changes in acid & alkaline phosphatease activity, cyclic AMP and $PGE_2$ production in time lapse after the application of mechanical stress. 1. In case of the marker enzyme of specific bone tissue cell, acid phosphatase activity was high in OC group and alkaline phosphatase activity was high in OB group. 2. After the mechanical stress was applied, acid phosphatase activity was decreased in both OC and OB groups and alkaline phosphatase activity was increase in OB group. 3. When the mechanical stress was applied for 15, 30 and 60 minutes, the production of $PGE_2$ increased in both OC and OB groups, as the time span increased. 4. When the mechanical stress was applied for 20 and 40 minutes, the production of $PGE_2$ increased in both OC and OB groups, as the time span increased.

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Development of A System Optimum Traffic Control Strategy with Cell Transmission Model (Cell Transmission 이론에 근거한 시스템최적 신호시간산정)

  • 이광훈;신성일
    • Journal of Korean Society of Transportation
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    • v.20 no.5
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    • pp.193-206
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    • 2002
  • A signal optimization model is proposed by applying the Cell-Transmission Model(CTM) as an embedded traffic flow model to estimate a system-optimal signal timing plan in a transportation network composed of signalized intersections. Beyond the existing signal-optimization models, the CTM provides appropriate theoretical and practical backgrounds to simulate oversaturation phenomena such as shockwave, queue length, and spillback. The model is formulated on the Mixed-Integer Programming(MIP) theory. The proposed model implies a system-optimal in a sense that traffic demand and signal system cooperate to minimize the traffic network cost: the demand departing from origins through route choice behavior until arriving at destinations and the signal system by calculating optimal signal timings considering the movement of these demand. The potential of model's practical application is demonstrated through a comparison study of two signal control strategies: optimal and fixed signal controls.

A theoretical Study on the Motive of Movement in Animation (애니메이션의 Movement 동인(動因)에 대한 이론적 고찰)

  • Lee Sang-Won
    • Journal of Science of Art and Design
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    • v.3
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    • pp.62-86
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    • 2001
  • This study is based on theoretical background about movements of visual communication highlighted in digital age. Such movements are variously expressed in animation with the advancement of media, and their expression has great effect on visual art. Artists' concern and endeavor about movement expression techniques have been continued by impressionism, expressionism, futurism, cubism closely related with the birth of movie from late 19th century to early 20th century. At that time, stationary 2D space in plane screen couldn't express movement or time directly. Later, artists and designers have attempted to approach illusions in pictures or 4 dimension and movements by 2D or 3D computer graphics. The visual image in present digital age is to see, to hear, to feel by timing, so it is necessary for the most efficient way of message communication. And then, it is the time to start new, scientific, and creative study about production techniques of animation and expression of movements, since domestic animation productions are rapidly changed from cell to digital. The aim of this study is to clarify the motive of movement by theoretical inquiry of animation. Various aspects of animation as synthetic art have been examined by mathematical, scientific, and philosophical viewpoint. The results will be useful to the expression of motions for maximization of emotional effect in animation production or basic data of virtual simulation about certain situation. Therefore, such study should be managed as multidisciplinary research in the rapidly changing visual culture paradigm. namely, animation includes much more imaginative & creative power than simple function or techniques, so it has to be recognized as special synthetic art(visual art) constructing an area, the formative art with philosophical viewpoint and scientific principles.

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A Study of Analysis and Comparison about Effective 'Stretch and Squash' in 3D Animation -Focusing on and - (3D 애니메이션작품에서 효율적인 스트레치와 스쿼시 적용 비교 분석에 관한 연구 -<톰과 제리(Tom and Jerry)>와 <인크레더블(The Incredibles)>을 중심으로-)

  • Kim, Yang-Soo
    • Cartoon and Animation Studies
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    • s.10
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    • pp.107-120
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    • 2006
  • The movement of characters in ceil animation is the art that gives the feeling of movement. The movement expressed naturally and well done makes the scene more dramatic and interesting. The history of 3D animation is not fully riped yet but it has shown powerful impact. The genre of 3D has come closer to us, yet it has given freshness and problems at the same time. One of the problems is the awkwardness of movement. Overplaying, stretching and squashing of character, was extremely difficult to accomplish using the prior technique of 3D so! ftware. It was not very effective so animators have avoided doing it. However, advanced technique of 3D software, so to speak, ‘stretch and squash’, overcomes the limitation of movement. The new form of character animation can be accomplished. The theme of this paper is about the analysis and comparison of ‘stretch and squash’ in cell and 3D animation.

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In vivo molecular and single cell imaging

  • Hong, Seongje;Rhee, Siyeon;Jung, Kyung Oh
    • BMB Reports
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    • v.55 no.6
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    • pp.267-274
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    • 2022
  • Molecular imaging is used to improve the disease diagnosis, prognosis, monitoring of treatment in living subjects. Numerous molecular targets have been developed for various cellular and molecular processes in genetic, metabolic, proteomic, and cellular biologic level. Molecular imaging modalities such as Optical Imaging, Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT), and Computed Tomography (CT) can be used to visualize anatomic, genetic, biochemical, and physiologic changes in vivo. For in vivo cell imaging, certain cells such as cancer cells, immune cells, stem cells could be labeled by direct and indirect labeling methods to monitor cell migration, cell activity, and cell effects in cell-based therapy. In case of cancer, it could be used to investigate biological processes such as cancer metastasis and to analyze the drug treatment process. In addition, transplanted stem cells and immune cells in cell-based therapy could be visualized and tracked to confirm the fate, activity, and function of cells. In conventional molecular imaging, cells can be monitored in vivo in bulk non-invasively with optical imaging, MRI, PET, and SPECT imaging. However, single cell imaging in vivo has been a great challenge due to an extremely high sensitive detection of single cell. Recently, there has been great attention for in vivo single cell imaging due to the development of single cell study. In vivo single imaging could analyze the survival or death, movement direction, and characteristics of a single cell in live subjects. In this article, we reviewed basic principle of in vivo molecular imaging and introduced recent studies for in vivo single cell imaging based on the concept of in vivo molecular imaging.

Efficiency Analysis Solar Cell of the Dynamic Boat's by SPA (SPA에 의한 동적인 보트의 태양전지 효율 분석)

  • Han, Jong-Ho;Lee, Jang-Myung
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.8
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    • pp.1529-1536
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    • 2011
  • Recently, worldwide government policy is pursuing saving energy and preservation. add to this, the solar cells are getting the spotlight nonpolluting energy source, using a variety of products for solar cell. in this paper, we'll make solar tracking system for suitable of dynamic boat. we knew that general boats are using fixed solar cell, it's first time to use tracking system of solar cells for boats so it is hard to application. To solve this problem in this paper we use to a magnetic compass and GPS for suitable solar tracking system of dynamic movement and to analyze fixed and tracking solar system. frist. solar tracking device is designed two-axis control system. one-axis control system is taken a magnetic compass for making efficiency defence solar tracking sensor, two-axis control system apply GPS latitude and longitude data for SPA(Solar position algorithm) so we know the azimuth and altitude. it analyze data value of accuracy comparison from result. so the proposed algorithm confirm to have validity.

Numerical Study on the Sub-Voxel Tracking Using Micro-Beads in a 3.0 T MRI (3.0 T MRI 환경에서 마이크로비드를 이용한 서브복셀 추적에 관한 수치해석적 연구)

  • Han, Byung-Hee;Lee, Soo-Yeol
    • Journal of Biomedical Engineering Research
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    • v.28 no.1
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    • pp.102-107
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    • 2007
  • In molecular imaging studies via magnetic resonance imaging, in vivo cell tracking is an important issue for the observation of cell therapy or disease behavior. High resolution imaging and longitudinal study are necessary to track the cell movement. Since the field inhomogeneity extends over several voxels, we have performed the numerical analysis using the sub-voxel method dividing a voxel of MR image into several elements and the information about the field inhomogeneity distribution around the micro-beads. We imbedded ferrite-composite micro-beads with the size of $20-150{\mu}m$ in the subject substituted for cells to induce local field distortion. In the phantom imaging with the isotropic voxel size of $200{\mu}m^3$, we could confirm the feasibility of sub-voxel tracking in a 3.0 T MRI.

Optimal Mobility Management of PCNs Using Two Types of Cell Residence Time (이동 통신망에 있어서 새로운 셀 체류시간 모형화에 따른 최적 이동성 관리)

  • 홍정식;장인갑;이창훈
    • Journal of the Korean Operations Research and Management Science Society
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    • v.27 no.3
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    • pp.59-74
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    • 2002
  • This study investigates two basic operations of mobility management of PCNs (Personal Communication Networks), i.e., the location update and the paging of the mobile terminal. From the realistic consideration that a user either moves through several cells consecutively or stays in a cell with long time, we model the mobility pattern by introducing two types of CRT (Cell Residence Time). Mobility patterns of the mobile terminal are classified Into various ways by using the ratios of two types of CRT. Cost analysis is performed for distance-based and movement-based location update schemes combined with blanket polling paging and selective paging scheme. It is demonstrated that in a certain condition of mobility pattern and call arrival pattern, 2-state CRT model produces different optimal threshold and so, is more effective than IID ( Independently-Identically-Distributed) CRT model. An analytical model for the new CRT model is compact and easily extendable to the other location update schemes.

Rap Signaling in Normal Lymphocyte Development and Leukemia Genesis

  • Minato, Nagahiro
    • IMMUNE NETWORK
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    • v.9 no.2
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    • pp.35-40
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    • 2009
  • Although Rap GTPases of the Ras family remained enigmatic for years, extensive studies in this decade have revealed diverse functions of Rap signaling in the control of cell proliferation, differentiation, survival, adhesion, and movement. With the use of gene-engineered mice, we have uncovered essential roles of endogenous Rap signaling in normal lymphocyte development of both T- and B-lineage cells. Deregulation of Rap signaling, on the other hand, results in the development of characteristic leukemia in manners highly dependent on the contexts of cell lineages. These results highlight crucial roles of Rap signaling in the physiology and pathology of lymphocyte development.

Langerhans Cell Histiocytosis Causing Cervical Myelopathy in a Child

  • Jang, Kun-Soo;Jung, Youn-Young;Kim, Seok-Won
    • Journal of Korean Neurosurgical Society
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    • v.47 no.6
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    • pp.458-460
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    • 2010
  • Langerhans cell histiocytosis (LCH), a disorder of the phagocytic system, is a rare condition. Moreover, spinal involvement causing myelopathy is even rare and unusual. Here, we report a case of atypical LCH causing myelopathy, which was subsequently treated by corpectemy and fusion. A 5-year-old boy presented with 3 weeks of severe neck pain and limited neck movement accompanying right arm motor weakness. CT scans revealed destruction of C7 body and magnetic resonance imaging showed a tumoral process at C7 with cord compression. Interbody fusion using cervical mesh packed by autologus iliac bone was performed. Pathological examination confirmed the diagnosis of LCH. After the surgery, the boy recovered from radiating pain and motor weakness of right arm. Despite the rarity of the LCH in the cervical spine, it is necessary to maintain our awareness of this condition. When neurologic deficits are present, operative treatment should be considered.