Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Numerical Study on the Sub-Voxel Tracking Using Micro-Beads in a 3.0 T MRI

3.0 T MRI 환경에서 마이크로비드를 이용한 서브복셀 추적에 관한 수치해석적 연구

  • 한병희 (경희대학교 동서의료공학과) ;
  • 이수열 (경희대학교 동서의료공학과)
  • Published : 2007.02.28
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Abstract

In molecular imaging studies via magnetic resonance imaging, in vivo cell tracking is an important issue for the observation of cell therapy or disease behavior. High resolution imaging and longitudinal study are necessary to track the cell movement. Since the field inhomogeneity extends over several voxels, we have performed the numerical analysis using the sub-voxel method dividing a voxel of MR image into several elements and the information about the field inhomogeneity distribution around the micro-beads. We imbedded ferrite-composite micro-beads with the size of $20-150{\mu}m$ in the subject substituted for cells to induce local field distortion. In the phantom imaging with the isotropic voxel size of $200{\mu}m^3$, we could confirm the feasibility of sub-voxel tracking in a 3.0 T MRI.

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