| 1 |
Pizon V, Chardin P, Lerosey I, Olofsson B, Tavitian A: Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region. Oncogene 3;201-214, 1988
PUBMED
|
| 2 |
Katagiri K, Hattori M, Minato N, Irie S, Takatsu K, Kinashi T: Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase. Mol Cell Biol 20;1956-1969, 2000
DOI
ScienceOn
|
| 3 |
Chen Y, Yu M, Podd A, Wen R, Chrzanowska-Wodnicka M, White GC, Wang D: A critical role of Rap1b in B-cell trafficking and marginal zone B-cell development. Blood 111;4627-4636, 2008
DOI
ScienceOn
|
| 4 |
Kometani K, Moriyama M, Nakashima Y, Katayama Y, Wang S-F, Saito T, Hattori M, Minato N: Essential role of Rap signal in pre-TCR-mediated  -selection checkpoint in alphabeta T cell development. Blood 112;4565-4573, 2008
DOI
ScienceOn
|
| 5 |
Seet CS, Brumbaugh RL, Kee BL: Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A. J Exp Med 199;
1689-1700, 2004
DOI
ScienceOn
|
| 6 |
Kurachi H, Wada Y, Tsukamoto N, Maeda M, Kubota H, Hattori M, Iwai K, Minato N: Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product. J Biol Chem 272;8081-28088, 1997
|
| 7 |
Wang SF, Aoki M, Nakashima Y, Shinozuka Y, Tanaka H, Taniwaki M, Hattori M, Minato N: Development of Notchdependent T-cell leukemia by deregulated Rap1 signaling. Blood 111;2878-2886, 2008
DOI
ScienceOn
|
| 8 |
Grabher C, von Boehmer H, Look AT: Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia. Nat Rev Cancer 6;347-359, 2006
DOI
ScienceOn
|
| 9 |
Weng AP, Ferrando AA, Lee W, Morris JP 4th, Silverman LB, Sanchez-Irizarry C, Blacklow SC, Look AT, Aster JC: Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306;269-271, 2004
DOI
PUBMED
ScienceOn
|
| 10 |
Lin YW, Nichols RA, Letterio JJ, Aplan PD: Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma. Blood 107;2540-2543, 2006
DOI
ScienceOn
|
| 11 |
Sasagawa S, Ozaki Y, Fujita K, Kuroda S: Prediction and validation of the distinct dynamics of transient and sustained ERK activation. Nat Cell Biol 7;365-373, 2005
DOI
ScienceOn
|
| 12 |
Quong MW, Martensson A, Langerak AW, Rivera RR, Nemazee D, Murre C: Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A. J Exp Med 199;1101-1112, 2004
DOI
ScienceOn
|
| 13 |
Minato N, Kometani K, Hattori M: Regulation of immune responses and hematopoiesis by the Rap1 signal. Adv Immunol 93;229-264, 2007
DOI
PUBMED
ScienceOn
|
| 14 |
Ciofani M, Schmitt TM, Ciofani A, Michie AM, Cuburu N, Aublin A, Maryanski JL, Z\acute{u}\tilde{n}iga-Pflücker JC: Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation. J Immunol 172;5230-5239, 2004
DOI
PUBMED
|
| 15 |
Katagiri K, Maeda A, Shimonaka M, Kinashi T: RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1. Nat Immunol 4;741-748, 2003
DOI
ScienceOn
|
| 16 |
O'Neil J, Grim J, Strack P, Rao S, Tibbitts D, Winter C, Hardwick J, Welcker M, Meijerink JP, Pieters R, Draetta G, Sears R, Clurman BE, Look AT: FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors. J Exp Med 204;1813-1824, 2007
DOI
ScienceOn
|
| 17 |
Hattori M, Minato N: Rap1 GTPase: functions, regulation, and malignancy. J Biochem 134;479-484, 2003
DOI
ScienceOn
|
| 18 |
Dumortier A, Jeannet R, Kirstetter P, Kleinmann E, Sellars M, dos Santos NR, Thibault C, Barths J, Ghysdael J, Punt JA, Kastner P, Chan S: Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice. Mol Cell Biol 26;209-220, 2006
DOI
ScienceOn
|
| 19 |
Duchniewicz M, Zemojtel T, Kolanczyk M, Grossmann S, Scheele JS, Zwartkruis FJ: Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion. Mol Cell Biol 26;643-653, 2006
DOI
ScienceOn
|
| 20 |
Dupuy AG, L'Hoste S, Cherfils J, Camonis J, Gaudriault G, de Gunzburg J: Novel Rap1 dominant-negative mutants interfere selectively with C3G and Epac. Oncogene 24;4509-4520, 2005
DOI
ScienceOn
|
| 21 |
Minato N, Hattori M: Spa-1 (Sipa-1) and Rap signaling in leukemia and cancer metastasis. Cancer Sci 100;17-23, 2009
DOI
ScienceOn
|
| 22 |
Tsukamoto N, Hattori M, Yang H, Bos JL, Minato N: Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion. J Biol Chem 274;18463-18469, 1999
DOI
PUBMED
|
| 23 |
Maillard I, Tu L, Sambandam A, Yashiro-Ohtani Y, Millholland J, Keeshan K, Shestova O, Xu L, Bhandoola A, Pear WS: The requirement for Notch signaling at the betaselection checkpoint in vivo is absolute and independent of the pre-T cell receptor. J Exp Med 203;2239-2245, 2006
DOI
ScienceOn
|
| 24 |
O'Neil J, Calvo J, McKenna K, Krishanamoorthy V, Aster JC, Bassing CH, Alt FW, Kelliher M, Look AT: Activating Notch1 mutations in mouse models of T-ALL. Blood 107;781-785, 2006
DOI
ScienceOn
|
| 25 |
Bos JL, de Rooij J, Reedquist KA: Rap1 signalling: adhering to new models. Nat Rev Mol Cell Biol 2;369-377, 2001
DOI
ScienceOn
|
| 26 |
Ishida D, Kometani K, Yang H, Kakugawa K, Masuda K, Iwai K, Suzuki M, Itohara S, Nakahata T, Hiai H, Kawamoto H, Hattori M, Minato N: Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice. Cancer Cell 4;55-65, 2003
DOI
ScienceOn
|
| 27 |
Ishida D, Su L, Tamura A, Katayama Y, Wang S-F, Taniwaki M, Hamazaki Y, Hattori M, Minato N: Rap1 signal controls B cell receptor repertoire and generation of self-reactive B1a cells. Immunity 24;417-427, 2006
DOI
ScienceOn
|
| 28 |
Bos JL: Linking Rap to cell adhesion. Curr Opin Cell Biol 17;123-128, 2005
DOI
PUBMED
ScienceOn
|
webmaster
