• IMMUNE NETWORK
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• v.11 no.5
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• pp.227-244
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• 2011

MicroRNAs (miRNAs) are small noncoding RNA molecules that negatively regulate gene expression via degradation or translational repression of their target messenger RNAs (mRNAs). Recent studies have clearly demonstrated that miRNAs play critical roles in several biologic processes, including cell cycle, differentiation, cell development, cell growth, and apoptosis and that miRNAs are highly expressed in regulatory T (Treg) cells and a wide range of miRNAs are involved in the regulation of immunity and in the prevention of autoimmunity. It has been increasingly reported that miRNAs are associated with various human diseases like autoimmune disease, skin disease, neurological disease and psychiatric disease. Recently, the identification of miRNAs in skin has added a new dimension in the regulatory network and attracted significant interest in this novel layer of gene regulation. Although miRNA research in the field of dermatology is still relatively new, miRNAs have been the subject of much dermatological interest in skin morphogenesis and in regulating angiogenesis. In addition, miRNAs are moving rapidly center stage as key regulators of neuronal development and function in addition to important contributions to neurodegenerative disorder. Moreover, there is now compelling evidence that dysregulation of miRNA networks is implicated in the development and onset of human neruodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Tourette's syndrome, Down syndrome, depression and schizophrenia. In this review, I briefly summarize the current studies about the roles of miRNAs in various autoimmune diseases, skin diseases, psychoneurological disorders and mental stress.

• Journal of Korea Foresty Energy
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• v.21 no.1
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• pp.49-55
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• 2002

A comparative study on the structure of wood and charcoals was examined by scanning electron microscopy. Four species as Quercus variabilis $B_LUME$, Quercus mongozica $F_ISCH$ , Fraxinus rhynchcphylla $H_ANCE$ and Prunus sargentii $R_EHDER$ were used for this experiment. Cell dimensions of charcoals showed more higher shrinkage than those of wood. Shape of vessels was slightly changed due to become smaller in tangential diameter. Therefore, it was considered that the decrease of charcoal yield was caused by decrease of cell dimensions as well as loss of wood components.

• Journal of Sensor Science and Technology
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• v.30 no.3
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• pp.170-174
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• 2021

As the rising attention to the medical and healthcare issue, Bio-MEMS (Micro electro mechanical systems) platform such as bio sensor, cell culture system, and microfluidics device has been studied extensively. Bio-MEMS platform mostly has high resolution structure made by biocompatible material such as polydimethylsiloxane (PDMS). In addition, three dimension structure has been applied to the bio-MEMS. Lithography can be used to fabricate complex structure by multiple process, however, non-rectangular cross section can be implemented by introducing optical apparatus to lithography technic. X-ray lithography can be used even for sub-micron scale. Here in, we demonstrated lines with round shape cross section using the tilted gold absorber which was deposited on the oblique structure as the X-ray mask. This structure was used as a mold for PDMS. Molded PDMS was applied to the cell culture platform. Moreover, molded PDMS was bonded to flat PDMS to utilize to the sub-micro channel. This work has potential to the large area bio-MEMS.

• Journal of the Korean Society of Marine Environment & Safety
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• v.17 no.4
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• pp.419-427
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• 2011

The characteristics for hydrogen production and the thermochemical properties of high temperature steam electrolysis(HTSE) device have been numerically analyzed in a two-dimension, steady-state with using the COMSOL $Multiphysics^{(R)}$. The main parameters for the calculation are applied voltage, ASR(Area-specific Resistance), temperature and pressure of the inlet gas flow. The results showed that thermal-neutral voltage was 1.2454 V and rather than the cell temperature increases or decreases with increasing applied voltage by thermal-neutral voltage starting this voltage the temperature in high voltage tended to rise and temperature in the low voltage tended to fall. And with, increasing the values of ASR, temperature inside the cell and the hydrogen production rate were decreased.

• Journal of the Korean Wood Science and Technology
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• v.16 no.2
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• pp.90-97
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• 1988

The rate of utilization of the oak cork (bark of Quercus variabilis Blume) ranges only 40-50%. Therefore, this study was carried out to investigate the chemical properties of the oak cork for increasing the utility. 1) The contents of alkali extractives, organic solvent extractives and ash in the oak cork are similar to those of other barks, but hot and cold water extractives and lignin contents are lower than those of the wood. The carbohydrate (cellulose and hemicellulose) content of the oak cork is similar to that of other barks. The suberin contents in the first and the second bark of the oak cork are 34.8 and 32.2% respectively, in the dry weight. 2) Inorganic component contents of the first bark are similar to those of the second. The pH of the first and the second bark are 3.9 and 4.2%. The caloric values of the first and second bark are 6,263 Kcal/kg, and 5,828 Kcal/kg, respectively, and these caloric values are higher than those of other barks. The sclerencymatous cell content of the first bark which is related to the quality of the oak cork is lower than that of second bark, the contents of the sclerenchymatous cell and lignin show the positive correlation. 3) In the dimension of the cross sectioned cork cell, the first bark is bigger than that of the second. The shape of the cork cell is globular shape in the early bark and discoid shape in the late bark. The cross and the radial section are the same shape, but the tangential section shows difference from the other section.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.42 no.5 s.335
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• pp.15-22
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• 2005

This paper proposes an efficient structure which is able to perform self-detection and self-repair for faults in a digital system by imitating the structure of living beings. The self-repair system is composed of artificial cells, which have homogeneous structures in the two-dimension, and spare cells. An artificial cell is composed of a logic block based on multiplexers, and a genome block, which controls the logic block. The cell is designed using DCVSL (differential cascode voltage switch logic) structure to self-detect faults. If a fault occurs in an artificial cell, it is self-detected by the DCVSL. Then the artificial cells which belong to the column are disabled and reconfigured using both neighbour cells and spare cells to be repaired. A self-repairable 2-bit up/down counter has been fabricated using Hynix $0.35{\mu}m$ technology with $1.14{\times}0.99mm^2$ core area and verified through the circuit simulation and chip test.

• Journal of the Korean Association of Geographic Information Studies
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• v.19 no.3
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• pp.127-143
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• 2016

This study explored the variability in the accuracy of dasymetric population estimation with different grid cell sizes. Dasymetric population maps for Fulton County, Georgia in the US were generated from 30m to 420m at intervals of 30m using an automated intelligent dasymetric mapping technique, population data, and original and simulated land use and cover data. The accuracies of dasymetric population maps were evaluated using RMSE and adjusted RMSE statistics. Lumped fractal dimension values were calculated for the dasymetric population maps generated from resolutions of 30m to 420m using the triangular prism surface area (TPSA) method. The results show that a grid cell size of 210m or smaller is required to estimate population more accurately in terms of thematic accuracy, but a grid cell size of 30m is required to meet an acceptable spatial accuracy of dasymetric population estimation in the study area. The fractal analysis also indicates that a grid cell size of 120m is the optimal resolution for dasymetric population estimation in the study area.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.28 no.9
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• pp.749-755
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• 2017

In this paper, a wideband microwave absorber for X-band(8~12 GHz) applications is proposed. The structure of the proposed absorber unit cell consists of a resonator with a slot and slit, a backing ground plate, and a Taconic RF-30(${\varepsilon}_r=3$, $tan{\delta}=0.0014$) substrate with a dimension of $8.5{\times}8.5{\times}0.5mm^3$. The proposed absorber has a dual resonance at 9.83 and 10.37 GHz. To demonstrate the operating principle of the proposed absorber structure at each resonance frequency, the simulated current distributions on the unit cell are analyzed. To verify the performance of the proposed absorber, a prototype absorber was fabricated with a planar array of $20{\times}20$ unit cells. The measured results exhibit two absorptivity peaks stronger than 99 % and full-width at half-maximum(FWHM) bandwidth of 1.1 GHz(9.51~10.61 GHz).

• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.9
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• pp.1347-1356
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• 2022

In this paper, we investigate the properties of CoGe thin film-based galvanic cells as a function of their dimension (cell length, width, etc.) and show their application as sensors to Arduino-based IoT sensor networks to detect water contact. Because these CoGe thin film-based galvanic cells do not require mechanical strains or temperature gradients unlike piezoelectric and thermoelectric energy harvesters, we think that these thin film-based galvanic cells are more suitable for self-powered sensor networks demanding sustainable and robust energy harvesters. In the past, a sputter-deposited CoGe thin film has not been intensively investigated for energy harvesting appilcations. Thus, in this study, we perform a feasibility study of galvanic cells composed of a sputter-deposited CoGe thin film to see if they can be applied as potential self-powered sensors. We believe that this paper will be of great help in developing even more enhanced sensor networks.

• 한국신재생에너지학회:학술대회논문집
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• 2010.06a
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• pp.58.1-58.1
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• 2010

In solar cell module manufacturing, single solar cells has to be joined electrically to strings. Copper stripes coated with tin-silver-copper alloy are joined on screen printed silver of solar cells which is called busbar. The bus bar collects the electrons generated in solar cell and it is connected to the next cell in the conventional module manufacturing by a metal stringer using conventional hot air or infrared lamp soldering systems. For thin solar cells, both soldering methods have disadvantages, which heats up the whole cell to high temperatures. Because of the different thermal expansion coefficient, mechanical stresses are induced in the solar cell. Recently, the trend of solar cell is toward thinner thickness below 180um and thus the risk of breakage of solar cells is increasing. This has led to the demand for new joining processes with high productivity and reduced error rates. In our project, we have developed a new method to solder solar cells with a laser heating source. The soldering process using diode laser with wavelength of 980nm was examined. The diode laser used has a maximum power of 60W and a scanner system is used to solder dimension of 6" solar cell and the beam travel speed is optimized. For clamping copper stripe to solar cell, zirconia(ZrO)coated iron pin-spring system is used to clamp both joining parts during a scanner system is traveled. The hot plate temperature that solar cell is positioned during lasersoldering process is optimized. Also, conventional solder joints after $180^{\circ}C$ peel tests are compared to the laser soldering methods. Microstructures in welded zone shows that the diffusion zone between solar cell and metal stripes is better formed than inIR soldering method. It is analyzed that the laser solder joints show no damages to the silicon wafer and no cracks beneath the contact. Peel strength between 4N and 5N are measured, with much shorter joining time than IR solder joints and it is shown that the use of laser soldering reduced the degree of bending of solar cell much less than IR soldering.