• Journal of Ginseng Research
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• 제42권1호
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• pp.116-121
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• 2018

Background: Black ginseng (BG) has greatly enhanced pharmacological activities relative to white or red ginseng. However, the effect and molecular mechanism of BG on muscle growth has not yet been examined. In this study, we investigated whether BG could regulate myoblast differentiation and myotube hypertrophy. Methods: BG-treated C2C12 myoblasts were differentiated, followed by immunoblotting for myogenic regulators, immunostaining for a muscle marker, myosin heavy chain or immunoprecipitation analysis for myogenic transcription factors. Results: BG treatment of C2C12 cells resulted in the activation of Akt, thereby enhancing hetero-dimerization of MyoD and E proteins, which in turn promoted muscle-specific gene expression and myoblast differentiation. BG-treated myoblasts formed larger multinucleated myotubes with increased diameter and thickness, accompanied by enhanced Akt/mTOR/p70S6K activation. Furthermore, the BG treatment of human rhabdomyosarcoma cells restored myogenic differentiation. Conclusion: BG enhances myoblast differentiation and myotube hypertrophy by activating Akt/mTOR/p70S6k axis. Thus, our study demonstrates that BG has promising potential to treat or prevent muscle loss related to aging or other pathological conditions, such as diabetes.

• Journal of Power Electronics
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• 제7권4호
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• pp.336-342
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• 2007

This paper presents the development of a fuel cell dynamic simulator using a programmable DC power supply and LabVIEW graphical user interface. The developed simulator closely describes the static and dynamic characteristics of an actual proton exchange membrance fuel cell (PEMFC). The experimental results are provided to verify the operation of the simulator. The developed simulator can be used as a convenient and economic alternative to an actual fuel cell for developing and testing a fuel cell power conditioning system.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2012년도 추계학술대회 논문집
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• pp.3-4
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• 2012

PV 시뮬레이터는 제한된 공간에서 PCS(Power Conditioning System)의 성능을 평가하거나, 고장유무를 검사하는데 필수적인 장비이다. PV 시뮬레이터가 PV 어레이와 동일한 동작을 하기 위해서는 다양한 재질의 PV cell에 대하여 모델링이 가능해야한다. 본 논문은 EN50530에 규정되어 있는 최대전력운 전범위인 $V_{MPP}{\pm}10%$ 구간에서 발생하는 오차를 다른 PV cell 모델링 알고리즘과 비교하고 제안한 알고리즘의 우수함을 증명하였다.

• 한국수정란이식학회지
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• 제6권2호
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• pp.47-51
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• 1991

This study investigated full-term development potential of ultrarap idly frozen and thawed mouse 2-cell embryos. Mouse 2-cell embryos, dehydrated by exposure to freezing medium, were directly immersed into liquid nitrogen and thawed in 37$^{\circ}C$ water. The embryos that were frozen and thawed were cultured in uitro and transferred to foster mothers to examine there developmental potential. As a result, the frozen-thawed 2-cell embryos developed to blastocysts in vitro as a similar rate as control 2-cell embryos did(in vitro 2-cell, 86.4%; in vivo 2-cell, 90.9%; solution control, 89.9%; control, 89.7%). Normal live young were obtained from transfer of frozen-thawed embryos to the oviduct and uterus of pseudopregnant recipients (3l.4~56.7%).

• 전력전자학회논문지
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• 제15권2호
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• pp.134-141
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• 2010

소형 PEM (Proton Exchange Membrane) 연료전지 시스템은 가습이 필요치 않아 상용화의 가능성이 크지만 그 제어 방법은 뚜렷하게 정립되어 있지 않다. 따라서 본 논문에서는 소형 PEM 연료전지 시스템의 제어를 위해 이중 루프 구조의 제어방식을 정립하고 DSP (Digital Signal Processor)를 이용하여 구현한다. 일반적으로 연료전지 시스템에서 제어의 핵심 요소는 크게 공기와 수소의 공급, 스택 내부의 수분 관리, 스택의 온도 관리로 나뉜다. 별도의 가습이 없이 공랭식으로 구동되는 소형 PEM 연료전지 스택의 제어에 있어서 팬은 스택의 공기 공급과 열관리 및 수분관리를 위한 핵심적인 역할을 하며, 퍼지밸브는 스택 내부의 잉여수분을 배출한다. 제안된 방식은 이중 제어루프를 이용한 팬의 제어를 통해 팬의 과도응답을 빠르게 하여 공기의 공급 속도를 개선시키며, 연료전지 스택의 전압변화를 피드백 하여 보상해줌으로써 연료전지가 부하변동에 대해 신속한 응답 특성을 갖도록 하였다. 제안된 방법의 유용함은 60W급 소형 PEM 연료전지 시스템의 실험과 이를 이용한 노트북 컴퓨터의 구동을 통해 검증된다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1992년도 한국자동제어학술회의논문집(국내학술편); KOEX, Seoul; 19-21 Oct. 1992
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• pp.1090-1095
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• 1992

This paper describes the systematic control method of process information transfer and machine cell control in FMS implementation. We have constructed an experimental FMS computer network and control system. The system hardware consists of host computer to manage process data and information transfer of machine cells, cell control computers to control machine cells(NC lathe, machining center). On the other hand, software is made up of oredr management module, NC program searching and generation module, NC part program error check module and cell control module. In this study, we could arrive at conclusion as following : The first, each task could be accomplihed by the efficient information transfer in hierachical computer network. The second, data base system of part programs and process control data is needed for the efficint information transfer and production management. Lastly, expansion of FMS control system could be achieved by the hierachical and decentralized computer control system.

• 대한한방소아과학회지
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• 제21권1호
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• pp.227-252
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• 2007

Objectives : In order to investigate the effect of Bobitang on SD rats with deteriorated immunity caused by methotrexate. Methods : The test sample were dosed once a day for 14 days by gastric gavage at a dosage 1,000, 500 and $250mg/kg/10m{\ell}$ from 2 days after last MTX-dosing, and the changes on body weight and gains, spleen weight and total blood leukocyte numbers, total lymphocyte numbers, the percentage of B-cell, T-cell, CD3+CD4+ T-cell, CD3+CD8+ T-cell and CD4+/CD8+ T-cell ratios in the blood and spleen were observed. Results : The changes on body weight gains, the spleen weight, the total blood leukocyte numbers, the total lymphocyte numbers in the blood and spleen, the ratio of T-cell in the blood and spleen, the ratio of CD3+CD4+ T-cell in the blood and spleen were increased significantly in BBT Extracts groups as compared with control group. The ratio of B-cell in the blood and spleen was not increased significantly in BBT Extracts groups as compared with control group. The percentage of CD3+CD8+ T-cell in the blood and spleen was decreased significantly in BBT Extracts groups as compared with control group. The ratio of CD4+/CD8+ T-cell in blood and spleen was increased significantly in BBT Extracts group as compared with control group. Conclusions : According to the above results, Bobi-Tang has an effect of increasing immune responses on SD rats with deteriorated immunity caused by methotrexate.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년도 학술대회
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• pp.386-389
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• 2008

In this paper grid generation of unstructured quadrilateral surface grids is described. The current approach uses conventional Advancing Front Method which is used to generate unstructured triangular grids. Grid cell size control is done by using closeness-based global interpolation method controlled by pre-described control elements. Algorithm and procedure for quadrilateral grid generation using AFM method and cell size control method are described. Examples of quadrilateral grid generation are shown, and difficulties and problems related to the current approach are also discussed.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년 추계학술대회논문집
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• pp.386-389
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• 2008

In this paper grid generation of unstructured quadrilateral surface grids is described. The current approach uses conventional Advancing Front Method which is used to generate unstructured triangular grids. Grid cell size control is done by using closeness-based global interpolation method controlled by pre-described control elements. Algorithm and procedure for quadrilateral grid generation using AFM method and cell size control method are described. Examples of quadrilateral grid generation are shown, and difficulties and problems related to the current approach are also discussed.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 학술대회 논문집 정보 및 제어부문
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• pp.511-513
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• 2005

The fuel cell system has inherent limitation such as slow response time and low fuel economy especially at the low power region, and thus, the battery system has come to be used to compensate for the fuel cell system. This type of hybrid configuration has many advantages, however, the energy management strategy is essentially required. The work in this paper presents survey on recent power management strategies for fuel cell hybrid electric vehicles. For three power management strategies: basic control method. object function-based control method, and fuzzy logic-based control method. each strategy is reviewed and discussed with other strategy.