• 제목/요약/키워드: cell composition

검색결과 1,419건 처리시간 0.028초

Experimental Investigation of the Effect of Composition on the Performance and Characteristics of PEM Fuel Cell Catalyst Layers

  • Baik, Jung-Shik;Seong, Dong-Mug;Kim, Tae-Min
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2007년도 춘계학술대회
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    • pp.157-160
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    • 2007
  • The catalyst layer of a proton exchange membrane (PEM) fuel cell is a mixture of polymer, carbon, and platinum. The characteristics of the catalyst layer play critical role in determining the performance of the PEM fuel cell. This research investigates the role of catalyst layer composition using a Central Composite Design (CCD) experiment with two factors which are Nafion content and carbon loading while the platinum catalyst surface area is held constant. For each catalyst layer composition, polarization curves are measured to evaluate cell performance at common operating conditions, Electrochemical Impedance Spectroscopy (EIS), and Cyclic Voltammetry (CV) are then applied to investigate the cause of the observed variations in performance. The results show that both Nafion and carbon content significantly affect MEA performance. The ohmic resistance and active catalyst area of the cell do not correlate with catalyst layer composition, and observed variations in the cell resistance and active catalyst area produced changes in performance that were not significant relative to compositions of catalyst layers.

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유전자 발현 데이터 기반 구강암에서의 세포 조성 차이 분석 (Distinct cell subtype composition using gene expression data in oral cancer)

  • 이제근
    • 한국융합학회논문지
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    • 제10권8호
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    • pp.59-65
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    • 2019
  • 암 조직에는 다양한 형태의 세포가 존재하지만, 이들의 조성을 실험적으로 확인하기는 매우 어렵다. 본 연구에서는 유전자 발현 데이터에 통계적 기계학습 모델을 적용하여 각 샘플의 세포 조성을 추론하고, 이러한 세포 조성이 암조직과 정상 조직간에 차이가 있는지를 확인하였다. 두 가지 서로 다른 회귀 모델을 이용하여 세포 조성을 예측한 결과 CD8 T cell과 Neutrophil이 구강암 조직에서 정상 조직에 비해 증가함을 확인할 수 있었다. 또한 비지도학습 중 하나인 t-SNE를 적용하여, 유추된 세포 조성에 의해 정상 조직과 구강암 조직이 서로 군집을 이루고 있음을 확인하였고, 지도 학습 기반의 다양한 분류 알고리즘들을 이용하여 세포 조성 정보를 이용하여 구강암과 정상 조직을 예측하는 것이 가능함을 보였다. 이 연구는 구강암의 면역 세포 침투에 대한 이해도를 증진하는데에 도움을 줄 수 있을 것이다.

미류나무 분화조직중 세포벽다당류의 화학적 성상 (Chemical Characteristics of Cell-Wall Polysaccharides in Differentiating Xylem of Populus deltoides M.)

  • 엄태진;박윤제
    • Journal of the Korean Wood Science and Technology
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    • 제26권3호
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    • pp.26-32
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    • 1998
  • The chemical composition of differentiating xylem of Populus deltoides M. were investigated and compared with those from sapwood. The cell wall polysaccharides were extracted sequentially from a differentiating xylem and sugar composition was analyzed with G.L.C, H.P.L.C and gel chromatograpy. The pectin substance and hemicellulose are rich in the cell wall of differentiating xylem. The $H_2O$ extract polysaccharides from differentiating xylem were composed with xylose-glucose residues which seem to be xyloglucan and a pectin. The arabinogalactan and the mannan were extracted with $Na_2CO_3$ solution and also the xylan was extracted with KOH solution. Sugar composition of each fractions in gel filteration of purified $H_2O$ polysaccharide suggests that the xyloglucan can be extracted with $H_2O$ from differentiating xylem.

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Therapeutic Potential of Membrane Fatty Acid Modifiaction in Tumor Cells

  • Shon, Yun-Hee;Park, Kun-Young;Kim, Kwang-Soo
    • Preventive Nutrition and Food Science
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    • 제1권1호
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    • pp.143-150
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    • 1996
  • The membrane fatty acid composition of tumor cell can be modified either in cell by altering the lipid composition of the medium of during growth in animals by changing the dietaty fat composition. These modifications are associated with changes in membrane physical properties and certain cellular functions, including carrier-mediated transport and enzyme contained within the membrane. Such effects influence the transport of nutrients and chemotherapeutic agents in cancer cells .Fatty acid modification also can enhance the sensitivity of the neoplastic cell to chemotherapy. The alteration in plasma membrane composition will be affected through dietary supplementations and the potential value to cancer patients could be a better understanding of the effects of diet on responsiveness of neoplasms to chemotherapy, i.e. cancer patients' chances for a "cure" can be improved by diet changes prior to treatment.

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직접 수소화붕소나트륨/과산화수소 연료전지의 산화극 연료 조성에 관한 연구 (A Study on Anode Fuel Composition of Direct Borohydride/Hydrogen Peroxide Fuel Cell)

  • 이태훈;유수상;오택현
    • 한국수소및신에너지학회논문집
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    • 제32권6호
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    • pp.514-523
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    • 2021
  • This study investigated the effect of anode fuel composition on the performance of direct borohydride/hydrogen peroxide fuel cells (DBHPFCs). The effect of sodium borohydride (NaBH4) and sodium hydroxide (NaOH) concentrations on fuel cell performance was determined through fuel cell tests. Fuel cell performance increased with an increase in the NaBH4 concentration, whereas it decreased with an increase in the NaOH concentration. The anode fuel composition was selected as 10 wt% NaBH4+10 wt% NaOH+80 wt% H2O based on the fuel viscosity, electrochemical reaction rate, and decomposition reaction rate. DBHPFCs were also tested to analyze the effect of operating temperature and operation time on fuel cell performance. The present results can be used as a reference basis to determine operating conditions of DBHPFCs.

상백피 추출물이 미생물의 균체성분 및 형태 변화에 미치는 영향 (Effects of Treatment with the Extract from the Root Bark of Morus alba on the Cell Composition and the Shape Change of Microorganisms)

  • 박욱연;성희경;목종수;장동석
    • 한국식품위생안전성학회지
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    • 제10권3호
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    • pp.147-153
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    • 1995
  • The ethanol extract from the root bark of Morus alba showed the strongest antimicrobial activity on the growth of almost all the tested microorganisms which were food-borne pathogens and food-related microorganisms. Therefore, fatty acid composition, amino acid composition and shape change of microorganisms treated with the ethanol extract from the root bark of Morus alba were examined. In effects of treatment with the ethanol extract on the fatty acid compositions of B. subtilis, S. aureus and E. coli, fatty aicd compositions such as hexadecanoic acid (16:0) and octadecanoic acid (18:2) of the tested strains were increased but pentadecanoic acid (15:0) heptadecanoic acid (17:0) and acid (16:1) and octadecenoic acid (18:1) of E. coli were decreased. The ethanol extract did not significantly affect the aminn acid composition of the tested strains. Transmission electron micrographs of microorgani는 treated with the ethanol extract exhibited morphological changes that irregularly contracted cell surface in S. aureus and destructed cell walls in B. subtilis and E. coli.

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Plating of Permalloy Using Flow Cell

  • Jeon, S.H.;Ahn, J.H.;Kang, T.
    • 한국표면공학회지
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    • 제32권3호
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    • pp.423-427
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    • 1999
  • Electroplating of 80%Ni permalloy thin plate for magnetic core materials. was studied The convected flow of electrolyte was used for stirring methode. The current density could be increased up to 250mA/$\textrm{cm}^2$ by flow cell. The composition of electroplated layer with vespect to current density and flow rate was investigated and experimental equation to predict the composition was made. How cell yielded more uniform thickness distribution than paddle cell did. The composition distribution was also studied. The thickness was the most important factor to the permeability. The permeability of 5$\mu\textrm{m}$plated permalloy was over 2000 at 1 MHz.

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Xyloglucan in the Differentiating Xylem of the Populus deltoides M.

  • Eom Tae-Jin;Park Soung-Bae
    • 펄프종이기술
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    • 제37권5호통권113호
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    • pp.25-34
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    • 2005
  • The chemical composition of the differentiating xylem of Populus deltoides M. was investigated and compared with that of sapwood. The cell wall polysaccharides were extracted sequentially from adifferentiating xylem and fractionated with gel chromatography. The sugar composition of each fraction was analyzed with G..C and H.P.L.C. The cell wall of the differentiating xylem is rich with the pectin substance and hemicellulose compared with that of sapwood. The water-extracted polysaccharides from the differentiating xylem were composed mainly of xylose and glucose residues. The sugar composition of some of the fractions in the gel filtration of purified $H_{2}O$ polysaccharide suggest that xyloglucan was extracted with $H_{2}O$ from differentiating xylem. Also, we can supposed that the purified $H_{2}O$ polysaccharide might be xyloglucan from the spectrometric data(IR and NMR) of purified $H_{2}O$ polysaccharide.

한방 입욕제 조성물이 MC/9 mast cell에서의 Th2 cytokine 발현에 미치는 영향 (Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells)

  • 장문희;최재송;최애련;안택원
    • 사상체질의학회지
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    • 제24권3호
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    • pp.80-92
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    • 2012
  • Objectives The purpose of this study is to investigate the effects of korean herbal bathing extracts composition 1 and composition 2 on Th2 cytokine production in MC/9 mast cells. Methods The effects of composition 1, 2 was analyzed by ELISA and Real-time PCR in MC/9 mast cells. Levels of IL-5, IL-13 were measured using enzyme-linked immunosorbent assays(ELISA). mRNA levels of IL-4, IL-5, IL-6, IL-13 were analyzed with Real-time PCR. Results Composition 1, 2 inhibited the IL-5, IL-13 production significantly(p<.001) in comparison to PI-control group at concentration of 100 ${\mu}g/mL$, 200 ${\mu}g/mL$. Composition 1, 2 inhibited the IL-4, IL-5, IL-13 mRNA expression significantly in comparison to PI-control group at concentration of 100 ${\mu}g/mL$, 200 ${\mu}g/mL$. Composition 1 inhibited the IL-6 mRNA expression significantly in comparison to PI-control group at concentration of 200 ${\mu}g/ml$. Composition 2 inhibited the IL-6 mRNA expression significantly in comparison to PI-control group at concentration of 100 ${\mu}g/mL$, 200 ${\mu}g/mL$. Conclusions These results indicate that composition 1, 2 has the effect of decreasing the Th2 cytokine production in the MC/9 mast cell.

Citronellol 및 Thymol이 Candida albicans 세포막 조성에 미치는 영향 (Effects of Citronellol and Thymol on Cell Membrane Composition of Candida albicans)

  • 임숙;신승원
    • 생약학회지
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    • 제40권4호
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    • pp.357-364
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    • 2009
  • Phospholipids are crucially important in a cell membrane function and could thereby influence antibiotic susceptibility. In order to investigate the antifungal mechanism the total lipid was extracted from C. albicans treated with citronellol or thymol in concentration of their minimum inhibiting concentration and the changes in phospholipids composition were analyzed using ketoconazole as control. The cell growth and total lipid synthesis in cell walls of C. albicans were inhibited by treatment with citronellol. The levels of total lipids were decreased by 35.85% compared to the control. They also showed a significant decrease in the contents of phospholipid, phosphatidylcholine(PC), phosphatidyl ethanolamine(PE) and phosphatidylinositol(PI). As the result of GC assay for total fatty acid methyl esters of PC, PE and PI in C. albicans treated with citronellol, it was found that the major fatty acid composed of three phospholipid were palmitic acid, stearic acid and oleic acid. Moreover, the pattern of the fatty acid compositions of PC, PE and PI were changed by the oil. Based on the results, the anti-Candida mechanism of citronellol or thymol might be closely associated with disrupting the permeability barriers of the fungal cell wall composition or construction.