• 제목/요약/키워드: cause of distress

검색결과 174건 처리시간 0.024초

Acute Respiratory Distress Syndrome as the Initial Clinical Manifestation of an Antisynthetase Syndrome

  • Kim, Seo-Hyun;Park, I-Nae
    • Tuberculosis and Respiratory Diseases
    • /
    • 제79권3호
    • /
    • pp.188-192
    • /
    • 2016
  • Antisynthetase syndrome has been recognized as an important cause of autoimmune inflammatory myopathy in a subset of patients with polymyositis and dermatomyositis. It is associated with serum antibody to aminoacyl-transfer RNA synthetases and is characterized by a constellation of manifestations, including fever, myositis, interstitial lung disease, mechanic's hand-like cutaneous involvement, Raynaud phenomenon, and polyarthritis. Lung disease is the presenting feature in 50% of the cases. We report a case of a 60-year-old female with acute respiratory distress syndrome (ARDS), which later proved to be an unexpected and initial manifestation of anti-Jo-1 antibody-positive antisynthetase syndrome. The present case showed resolution of ARDS after treatment with high-dose corticosteroids. Given that steroids are not greatly beneficial in the treatment of ARDS, it is likely that the improvement of the respiratory symptoms in this patient also resulted from the prompt suppression of the inflammatory systemic response by corticosteroids.

알칼리-실리카 반응에 의한 시멘트 콘크리트 포장 파손 사례 (A Case Study for Deterioration due to Alkali-Silica Reaction in the Cement Concrete Pavement)

  • 홍승호;한승환;윤경구
    • 콘크리트학회논문집
    • /
    • 제18권3호
    • /
    • pp.355-360
    • /
    • 2006
  • 알칼리-실리카 반응은 시멘트 콘크리트 포장 및 구조물에 매우 심각한 손상을 일으킬 수 있다. 국내의 경우 알칼리-실리카 반응에 의한 피해 사례가 거의 보고되지 않아 연구는 적게 수행되고 있는 실정이다. 본 연구는 국내 고속도로 일부 노선의 시멘트 콘크리트포장에서 발생한 불규칙균열과 스폴링의 발생 원인을 분석하기 위해 수행되었다. 본 연구에서는 현장조사, 화학적인 방법 및 전자현미경(SEM)의 에너지 분석기(EDX)를 사용하여 파손 원인을 분석하였다. 조사 대상 시멘트 콘크리트 포장의 파손 유형은 불규칙 균열과 스폴링이다. 코어 시편의 균열 절단면에서 편암과 편마암 골재 주위로 백색으로 변색된 반응환이 관찰되었고, 반응 생성물에서는 $Si^{4+}>K^+$성분이 주로 분석되었다. 254nm 파장의 자외선 광선을 비추게 되면 알칼리-실리카 반응부에 화학반응에 의하여 노란색 형광 빛을 나타나는 것으로 분석되었다. 본 연구를 통하여 조사 대상 시멘트 콘크리트 포장에 발생한 불규칙 균열 및 스폴링은 주로 알칼리-실리카 반응에 의해 유발된 것으로 판정하였다.

강원도 야생동물 포유류의 조난.구조 실태분석 (Analysis of the wildlife distress and rescue of wild animal mammals in Gangwon province)

  • 박인철;이호원;김종택
    • 한국동물위생학회지
    • /
    • 제35권1호
    • /
    • pp.33-37
    • /
    • 2012
  • As people's interest about wildlife animal increases, more wildlife animal centers are developing. In South Korea, currently 120 mammal species live, and 22 of them are designated as endangered species. It is important to protect these natural treasures and endangered species, because they are being harmed by human industrial activity. For example, road expansion and poaching have led to the destruction of wildlife animal habitats, which is increasing year by year. Nevertheless, data regarding the systematic treatment of wild animals that are in distress is lacking, and it is a reality that analysis of such data is also lacking. The Kangwon Wildlife Rescue Center investigates these types of distress experienced by mammals. By analyzing the shape of the wild animals killed or injured, the center seeks an efficient and systematic way to manage such distress. The data collected from the Wildlife Animal Center from September 2007 to August 2010 includes 195 different cases, and the animals point of rescue. There are 16 species, including 87 water deer (Hydropotes inermis), 39 raccoons (Nyctereutes procyonoides), 20 roe deer (Capreolus pygargus bedfordi), 10 goral (Nemorhaedus goral), 7 siberian weasels (Mustela sibirica), 6 otters (Lutra lutra) and etc. Within the first year (September 2007 to August 2008), the number of mammals rescued was 46. In the second year (September 2008 to August 2009), 60 animals were rescued. in the third year (September 2009 to August 2010), the Wildlife Animal Center had 89 animals. We can see that these numbers are increasing, which shows that people are interested in the well-being of these animals because they are reporting animal injuries more and more. The mains form of distress caused by humans are from car accidents 67 (34.4%). Traps, and other hunting tools used by poachers are responsible for 25 (13.0%). Also, human industrial activity thus indirectly led to the starvation 25 (13.0%). and the orphaning of young animals 37 (19.0%).

경남소재 일개조선소 근로자의 건강이상소견과 아르곤 용접과의 관련성 (Association between Subjective Distress Symptoms and Argon Welding among Shipyard Workers in Gyeongnam Province)

  • 최우호;진성미;권덕헌;김장락;강윤식;정백근;박기수;황영실;홍대용
    • 한국산업보건학회지
    • /
    • 제24권4호
    • /
    • pp.547-555
    • /
    • 2014
  • Objective: This study was conducted to investigate the association between subjective distress symptoms and argon welding among workers in Gyeongnam Province shipyard. Method: 31 argon and 29 non-argon welding workers were selected as study subjects in order to measure concentrations of personal dust, welding fumes and other hazardous materials such as ZnO, Pb, Cr, FeO, MnO, Cu, Ni, $TiO_2$, MgO, NO, $NO_2$, $O_3$, $O_2$, $CO_2$, CO and Ar. An interviewer-administered questionnaire survey was also performed on the same subjects. The items queried were as follows: age, height, weight, working duration, welding time, welding rod amounts used, drinking, smoking, and rate of subjective distress symptoms including headache and other symptoms such as fever, vomiting and nausea, metal fume fever, dizziness, tingling sensations, difficulty in breathing, memory loss, sleep disorders, emotional disturbance, hearing loss, hand tremors, visual impairment, neural abnormality, allergic reaction, runny nose and stuffiness, rhinitis, and suffocation. Statistical analysis was performed using SPSS software, version 18. Data are expressed as the mean ${\pm}SD$. An ${\chi}^2$-test and a normality test using a Shapiro wilk test were performed for the above variables. Logistic regression analysis was also conducted to identify the factors that affect the total score for subjective distress symptoms. Result: An association was shown between welding type (argon or non-argon welding) and the total score for subjective distress symptoms. Among the rate of complaining of subjective distress symptoms, vomiting and nausea, difficulty breathing, and allergic reactions were all significantly higher in the argon welding group. Only the concentration of dust and welding fumes was shown to be distributed normally after natural log transformation. According to logistic regression analysis, the correlations of working duration and welding type (argon or non-argon) between the total score of subjective distress symptoms were found to be statistically significant (p=0.041, p=0.049, respectively). Conclusion: Our results suggest that argon welding could cause subjective distress symptoms in shipyard workers.

한 작은 섬에서의 파라콰트 집단중독 (Mass paraquat poisoning in a small island community (case report))

  • 이성우;정태화;최강원;임정기;이덕형
    • Journal of Preventive Medicine and Public Health
    • /
    • 제22권4호
    • /
    • pp.454-465
    • /
    • 1989
  • In a small island community with a population of less than 100 residents, nine persons died and five experienced severe illnesses during the period from November 1986 to May 1988. Their initial symptoms were sore throat and fever. Renal failure and hepatitis developed within one week after the onset. Oral mucosal ulcer developed in some cases. After one week, progressive respiratory failure and dyspnea developed evidently and severe respiratory distress and hypoxia preceded those fatal cases. Chest X-ray findings revealed bilateral diffuse multiple cystic lesion with occasional multiple large emphysematous bullae. Based on these features paraquat poisoning was diagnosed and route of poisoning was investigated. In three sources of drinking water, trace amount of paraquat was detected in November 1988, six months after the incidence of recent fatal case. In November 1988, soybean sauces and soybean pastes from 12 households were found contaminated with high concentration of paraquat, the cause could not be identified. The possibility of the contamination of drinking water as the cause of this mass poisoning has been suggested.

  • PDF

Subphenotypes of Acute Respiratory Distress Syndrome: Advancing towards Precision Medicine

  • Andrea R. Levine;Carolyn S. Calfee
    • Tuberculosis and Respiratory Diseases
    • /
    • 제87권1호
    • /
    • pp.1-11
    • /
    • 2024
  • Acute respiratory distress syndrome (ARDS) is a common cause of severe hypoxemia defined by the acute onset of bilateral non-cardiogenic pulmonary edema. The diagnosis is made by defined consensus criteria. Supportive care, including prevention of further injury to the lungs, is the only treatment that conclusively improves outcomes. The inability to find more advanced therapies is due, in part, to the highly sensitive but relatively non-specific current syndromic consensus criteria, combining a heterogenous population of patients under the umbrella of ARDS. With few effective therapies, the morality rate remains 30% to 40%. Many subphenotypes of ARDS have been proposed to cluster patients with shared combinations of observable or measurable traits. Subphenotyping patients is a strategy to overcome heterogeneity to advance clinical research and eventually identify treatable traits. Subphenotypes of ARDS have been proposed based on radiographic patterns, protein biomarkers, transcriptomics, and/or machine-based clustering of clinical and biological variables. Some of these strategies have been reproducible across patient cohorts, but at present all have practical limitations to their implementation. Furthermore, there is no agreement on which strategy is the most appropriate. This review will discuss the current strategies for subphenotyping patients with ARDS, including the strengths and limitations, and the future directions of ARDS subphenotyping.

Competition Impacts on the Financial Distress of Firms in the Healthcare Sector in India

  • Venkata Mrudula, BHIMAVARAPU;Jagjeevan, KANOUJIYA;Vikas, TRIPATI;Pracheta, TEJASMAYEE;Rameesha, KALRA;Sanjeev, KADAM;Poornima, TAPAS;Shailesh, RASTOGI
    • The Journal of Asian Finance, Economics and Business
    • /
    • 제10권2호
    • /
    • pp.175-181
    • /
    • 2023
  • Competition assures improved products and services to meet customers' needs. The soundness of a firm's financial health is crucial for the country's economic well-being. Distressed companies cause investor panic, which has a knock-on effect on the economy and leads to a deterioration in the image and value of the companies. This paper aims to empirically investigate the influence of competition on financial distress (FD) in the healthcare industry using the Altman Zscore values as the proxy for FD. This study uses secondary data from ten healthcare companies operating in India between 2016 and 2020. The study's findings indicate a significant negative relation with the exogenous variables of the study, implying that a higher level of competition enhances a firm's FD or adversely affects financial health. The main implication of the study is two-pronged. Firstly, the firms' managers and decision-makers need not worry about competition as a deterrent to stability. Secondly, the policymakers need not be concerned that high competition may lead to financial stress for the firms. Therefore, this paper concludes that competition is good for firms operating in India.

Risk factors for respiratory distress syndrome in full-term neonates

  • Kim, Jin Hyeon;Lee, Sang Min;Lee, Young Hwan
    • Journal of Yeungnam Medical Science
    • /
    • 제35권2호
    • /
    • pp.187-191
    • /
    • 2018
  • Background: Respiratory distress syndrome (RDS) is a one of the most common cause of respiratory morbidity and mortality in neonates. This study was conducted to investigate the risk factors for RDS in full-term neonates. Methods: We conducted this retrospective study using medical records. The study group included 80 full-term neonates diagnosed with RDS and hospitalized in the neonatal intensive care unit between January 2012 and December 2016, at Yeungnam University Hospital. We analyzed sex, gestational age, birth weight, delivery method, maternal age, number of pregnancy, history of abortion, and complication of pregnancy. The control group included 116 full-time neonates who were hospitalized with jaundice during the same period. Results: The incidence of full-term RDS was more common in males (odds ratio [OR], 3.288; 95% confidence interval [CI], 1.446-7.479), cesarean section (OR, 15.03; 95% CI, 6.381-35.423), multiparity (OR, 4.216; 95% CI, 1.568-11.335). The other factors rendered no significant results. Conclusion: The risk factors for RDS in full-tern neonates were identified as male sex, cesarean section, and multiparity. Further studies involving more institutions are needed to clarify the risk factors for RDS in full-term infants.

Acute Respiratory Distress Syndrome after Rotavirus Infection in a C1q Nephropathy Patient: A Case Report

  • Kim, Hye Jin;Min, Jeesu;Kim, Ji Hyun;Choi, Yu Hyeon;Han, Mi Seon;Ha, Il-Soo;Kang, Hee Gyung
    • Childhood Kidney Diseases
    • /
    • 제25권2호
    • /
    • pp.122-127
    • /
    • 2021
  • C1q nephropathy is a rare glomerulopathy that typically presents with nephrotic syndrome in children. Treatment with immunosuppressive agents renders patients vulnerable to infection and its complications. Gastroenteritis is common in children, and rotavirus is a leading cause. Extraintestinal manifestations of rotavirus have recently been reported; however, there is a paucity of cases exploring the involvement of a rotavirus on the respiratory system. Acute respiratory distress syndrome (ARDS) is a rapid onset respiratory failure characterized by noncardiogenic pulmonary edema and hypoxemia. Causes of ARDS include sepsis, pneumonia, pancreatitis, aspiration, and trauma. In this paper, we report a case of ARDS after rotavirus infection in a child with C1q nephropathy who had been treated with immunosuppressive agents.